Clinical trials: Renal Impairment
Protein-Energy Malnutrition, Kidney Failure, Chronic
Egg Albumin-Based Protein Supplement Versus Renal-specific Supplement in Hemodialysis Patients
Malnutrition is seen frequently in hemodialysis units in most developing countries. Malnutrition increases morbidity and mortality in this population and its treatment improves patient survival and health status The purpose of…
- Conditions
- Protein-Energy Malnutrition, Kidney Failure, Chronic, Hemodialysis
- Trial name
- NCT01981083
- Testing
- Egg albumin-based protein supplement, Renal-specific oral supplement
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Centro Medico Lic Adolfo Lopez Mate
Acute Kidney Injury
Clinical Validation of NAVOY® Acute Kidney Injury in Swedish ICU Patients
The study aims to evaluate the performance of the prediction algorithm NAVOY® AKI in a Swedish adult ICU patient population versus fulfilment of KDIGO diagnostic criteria.
- Trial name
- ExTRACT (NCT05424874)
- Where
- Sweden
- Volunteers
- 304 people
- Sponsor
- AlgoDx
Chronic Kidney Diseases, Overweight and Obesity
Effect a Honey, Spice-blended Baked Good Has on Salivary Inflammation Markers in Adults: a Pilot Study
The purpose of this research is to determine the effect a spiced-infused baked good has on inflammatory biomarkers in adults who are overweight and/or who has chronic kidney disease.
- Trial name
- NCT05055362
- Testing
- Honey Spice Group
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Florida
Ischemia, Fatty Acid-Binding Proteins
Kidney and Intestinal Markers for Early Detection of Organ Injury After Endovascular Aortic Repair
This study aims to investigate the predictive value of novel biomarkers and contrast-enhanced ultrasonography for early detection of abdominal end-organ (kidney and intestinum) hypoperfusion and ischemia in patients undergoing…
- Conditions
- Ischemia, Fatty Acid-Binding Proteins, Mesenteric Vascular Disease, Acute Kidney Injury
- Trial name
- KISMED (NCT01915446)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Regensburg
Hemodialysis, Hypercholesterolemia
Malnutrition and Inflammation in Dialysis Patients in Taiwan
According to the reports of the United States Renal Data System (USRDS), there is a 25% annual mortality rate with nearly 50% of all reported maintenance hemodialysis (HD) patient deaths attributed to atherosclerosis-related…
- Conditions
- Hemodialysis, Hypercholesterolemia, Malnutrition, Inflammation
- Trial name
- NCT00173823
- Where
- Taiwan
- Volunteers
- 1,500 people
- Sponsor
- National Taiwan University Hospital
Chronic Kidney Disease, Diet Interventions
Dine and DASH Into Wellness Pilot Study
The purpose of this study is to determine the feasibility and acceptability of a16-week diet coaching program enhanced with cooking classes to improve adherence to the Dietary Approaches to Stop Hypertension (DASH) diet among…
- Conditions
- Chronic Kidney Disease, Diet Interventions, Disease Prevention
- Trial name
- NCT07175896
- Testing
- Immediate delivery of low-sodium DASH (Dietary Approaches to Stop Hypertension) diet group coaching plus hand-on cooking program, Delayed delivery of low-sodium DASH (Dietary Approaches to Stop Hypertension) diet group coaching plus hand-on cooking program
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Duke University
Kidney Failure, Chronic
Creation of Arteriovenous Ante-brachial Fistula Under Axillary Block Versus Local Anesthesia : Impact on Early Complications
Recommended by the KDOQI vascular access guidelines, antebrachial arteriovenous fistula is the best primary vascular access for hemodialysis in patients with end stage renal disease.
- Trial name
- FAV ss ALR (NCT02722096)
- Testing
- Axillary block anesthesia with Ropivacaine and Lidocaine, Local anesthesia with Ropivacaine and Lidocaine
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Hospices Civils de Lyon
Chronic Kidney Failure
Phase III Study to Investigate the Safety and Efficacy of Fermagate and Sevelamer Hydrochloride
Magnesium iron hydroxycarbonate is a phosphate binder that absorbs phosphate from food, reducing the amount that the body can absorb.
- Trial name
- NCT00844662
- Testing
- Fermagate, Sevelamer hydrochloride
- Where
- 109 sites in United States, Belgium and 13 more
- Volunteers
- 1,000 people
- Sponsor
- Ineos Healthcare Limited
Kidney Failure,Chronic
Safety, Effectiveness and Manipulability Evaluation of a Domestic PD Machine
This study is a randomized, multi-center，crossover study of a domestic FM peritoneal dialysis machine and Baxter HOMECHOICE.It aims to verify safety, effectiveness and manipulability of a domestic peritoneal dialysis machine.
- Trial name
- NCT02525497
- Testing
- FM peritoneal dialysis machine, HOMECHOICE peritoneal dialysis machine
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Chinese PLA General Hospital
Dialysis Patients
Intradialytic Exercise With Blood Flow Restriction in Hemodialysis Patients
The main objective is to evaluate in hemodialysis patients the effects of two intradialytic rehabilitation programs based on physical exercise, with or without the application of blood flow restriction, on myocardial stunning and…
- Trial name
- ERO-CARD (NCT07269379)
- Testing
- Chronic phase - HDEX/HDBFRE, Acute phase - HDEX/HDBFRE
- Where
- 2 sites in France
- Volunteers
- 108 people
- Sponsor
- University of Avignon
End-Stage Renal Disease
Aspirin in the Prevention of Cardiovascular Events in Hemodialysis Patients
The study is prospectively initiated to: (1) evaluate the alterations in platelet function to aspirin therapy and the prevalence of aspirin resistance in patients with chronic kidney disease undergoing hemodialysis, and (2)…
- Trial name
- NCT01198379
- Testing
- aspirin
- Where
- Taiwan
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Contrast Induced Acute Kidney Injury
Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI
This phase 2 study is to assess the safety and efficacy of APX-115 active doses in Contrast Induced Acute Kidney Disease compared to placebo following multiple oral dosing in patients with undergoing percutaneous coronary…
- Trial name
- NCT05758896
- Testing
- Isuzinaxib (APX-115)
- Where
- 14 sites in United States, South Korea
- Volunteers
- 218 people
- Sponsor
- Aptabio Therapeutics, Inc.
Chronic Disease, Chronic Diseases in Adolescence
Home-based Aerobic Training Among Adolescents With Chronic Diseases During COVID-19 Pandemic
Data show that the coronavirus disease 2019 (COVID-19) symptoms can be severe in 4% and 3% of the adolescents aged 11-15 years and ≥ 16 years, respectively.
- Conditions
- Chronic Disease, Chronic Diseases in Adolescence, Chronic Disease of Immune System, Chronic Kidney Diseases
- Trial name
- NCT04458246
- Testing
- Exercise training group
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- University of Sao Paulo
Renal Insufficiency, Chronic, Diabetes Mellitus, Type 2
Pilot Assessment of the Effects of Bardoxolone Methyl on Renal Perfusion, Systemic Haemodynamics and Cardiac Function in Patients With Chronic Kidney Disease and Type 2 Diabetes
This study is to evaluate the variability of several pharmacodynamic measures of kidney function, cardiovascular function, cerebral perfusion, and haemodynamics.
- Trial name
- NCT01551446
- Testing
- Bardoxolone Methyl
- Sponsor
- Biogen
End Stage Renal Disease (ESRD)
Study of Myfortic in Combination With Tacrolimus and Thymoglobulin in Early Corticosteroid Withdrawal
To determine the safety and efficacy of a new formulation of Myfortic in combination with tacrolimus and thymoglobulin.
- Trial name
- NCT00374803
- Testing
- Mycophenolic Acid (Myfortic)
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Cincinnati
Acute Kidney Injury
Molecular Effects of Vitamin B3 (Niacinamide) in Acute Kidney Injury
This is a single center, randomized, single-blind, placebo-controlled study to evaluate the safety and biochemical effects of niacinamide on metabolic parameters of the kidney in patients undergoing cardiac surgery.
- Trial name
- NCT02701127
- Testing
- Oral niacinamide, 1 gram daily, Oral niacinamide, 3 gram daily
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Beth Israel Deaconess Medical Center
Infection, Heart Failure
Prediction of 30-Day Readmission Using Machine Learning
This is a retrospective observational study drawing on data from the Brigham and Women's Home Hospital database. Sociodemographic and clinic data from a training cohort were used to train a machine learning algorithm to predict…
- Conditions
- Infection, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT04849312
- Where
- 2 sites in United States
- Volunteers
- 372 people
- Sponsor
- Brigham and Women's Hospital
Acute Kidney Injury
The Furosemide Stress Test, Electrolytes Response and Renal Index in Critically Ill Patients
Aim of the present study is to compare the response to furosemide stress test in term of diuresis and electrolytes and of the renal index in mechanically ventilated patients at admission and after 3 days in patients with and…
- Trial name
- NCT04215419
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Hospital San Paolo
End Stage Renal Disease (ESRD)
Effect of PMR on Pain In Patients With ESRD
Background: Patients with chronic end-stage renal disease (ESRD) commonly experience chronic pain, which significantly impair their quality of life.
- Trial name
- NCT07061028
- Testing
- Progressive Muscle Relaxation, Control Group
- Where
- Jordan
- Volunteers
- 104 people
- Sponsor
- Jordan University of Science and Technology
Valvular Disease, Valvular Heart Disease
Epidemiology and Long-term Outcome of Patients With VHD
Valvular heart diseases are significant problem in Polish population. Coexistence of coronary artery disease in patients with VHD increases the risk of death and affects further therapeutic strategy.
- Conditions
- Valvular Disease, Valvular Heart Disease, Aortic Valve Stenosis, Mitral Insufficiency and Aortic Stenosis
- Trial name
- BIA-WAD (NCT04527367)
- Testing
- Innovative medical technologies in invasive cardiology and cardiac surgery
- Where
- Poland
- Volunteers
- 2,500 people
- Sponsor
- Medical University of Bialystok
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