Clinical trials: Renal Impairment
Chronic Kidney Disease
The Prevention of Contrast Induced Nephropathy by Sarpogrelate in Patients With Chronic Kidney Disease
Background: Contrast-induced nephropathy (CIN) is a serious clinical problem associated with increased morbidity and mortality, particularly in patients with chronic renal insufficiency.
- Trial name
- NCT01165567
- Testing
- sarpogrelate
- Where
- South Korea
- Volunteers
- 212 people
- Sponsor
- Seoul National University Boramae Hospital
End Stage Renal Failure, Hemodialysis Access Failure
Outcomes for One-stage and Two-stage Brachial Basilic Arteriovenous Fistulas
An arteriovenous (AV) fistula is essential for patients with kidney failure on dialysis. There is no clear data on the best method to create a new brachial basilic AV fistula (BBAVF), so the choice between a single procedure and…
- Conditions
- End Stage Renal Failure, Hemodialysis Access Failure, Arterio-venous Fistula
- Trial name
- NCT04376567
- Testing
- One stage approach
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Tze-Woei Tan
Acute Kidney Failure
BNP (Nesiritide) vs. Placebo to Protect Kidney Function in Patients Undergoing Heart Bypass Surgery.
Use of BNP (nesiritide) vs placebo to help protect kidney function in patients undergoing heart bypass surgery.
- Trial name
- NCT00252200
- Testing
- Neseritide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Chronic Kidney Disease, Decision-making
A Video Decision Support Tool to Assist Elderly Patients in ESRD Treatment Decision-making
In the United States, it is estimated that there are approximately 630,000 patients who have ESRD with two-thirds of those patients subsequently receiving maintenance dialysis.
- Trial name
- NCT02698722
- Testing
- End-stage renal disease treatment options
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Chronic Kidney Diseases
Assessing Bone Calcium Content in Children With Kidney Disease Treated With Two Different Medicines
This is an open label, time series trial. The trial is likely to be single centre (additional sites will only be opened if necessary) and will involve 25 children with chronic kidney disease (stage 3b, 4-5) or on dialysis.
- Trial name
- CAL-BAL (NCT04120922)
- Testing
- calcium carbonate, sevelamer carbonate
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University College, London
Cardiac Surgery, Vasoplegia
Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin II
The study intervention focuses on exploring the use of angiotensin II as a primary vasopressor compared to norepinephrine in cardiac surgery patients to investigate whether angiotensin II can reduce the occurrence of…
- Trial name
- PAN-AKI (NCT06615102)
- Testing
- Angiotensin II, Noradrenalin
- Where
- 4 sites in Germany
- Volunteers
- 1,022 people
- Sponsor
- Universität Münster
End Stage Renal Disease, Hemodialysis Patients
Association Between Dose Dialysis by Kt and Mortality
The aim of this study is to assess whether patients receiving current recommendations of an adequate dialysis dose by Kt adjusted for body surface area improved survival at 24 months compared to those who do not get it, as well…
- Trial name
- NCT01932853
- Where
- Spain
- Volunteers
- 6,129 people
- Sponsor
- NephroCare Spain
Stable Angina, Acute Kidney Injury
CI-AKI in Patients With Stable CAD and Comorbidities. Are we Doing Better?
Patients aged 18-89 with stable CAD and comorbidities receiving optimal medical treatment requiring PCI with iodinated contrast media.
- Conditions
- Stable Angina, Acute Kidney Injury, Contrast-induced Nephropathy
- Trial name
- NCT04014153
- Testing
- Iodinated contrast media
- Volunteers
- 1,023 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
End Stage Renal Failure, Neuropathic Pain
Qutenza for Critical Ischaemia in End Stage Renal Failure
Critical ischaemia is pain at rest as the result of poor blood flow and lack of oxygen being delivered to the tissues. It normally affects the hands and feet and can be very debilitating.
- Trial name
- NCT01704339
- Testing
- QUTENZA
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Emma Aitken
Anemia of Chronic Kidney Disease
PBF-1681 (Ferric Citrate) for the Treatment of IDA in Patients With NDD-CKD
To assess the safety and effectiveness of PBF-1681 for the treatment of Iron Deficiency Anemia in patients with Non-Dialysis Dependent Chronic Kidney Disease.
- Trial name
- NCT04543812
- Testing
- Ferric citrate
- Where
- 12 sites in Taiwan
- Volunteers
- 141 people
- Sponsor
- Panion & BF Biotech Inc.
Kidney Transplantation, Delayed Graft Function
Context - Remote Ischemic Conditioning in Renal Transplantation - Effect on Immediate and Extended Kidney Graft Function
The purpose of this study is to determine whether remote ischemic conditioning can improve the outcome after renal transplantation with deceased donor.
- Conditions
- Kidney Transplantation, Delayed Graft Function, Acute Kidney Injury, Glomerular Filtration Rate
- Trial name
- Context (NCT01395719)
- Testing
- Remote ischemic conditioning
- Where
- 4 sites in Denmark, Netherlands and 1 more
- Volunteers
- 220 people
- Sponsor
- University of Aarhus
Type 2 Diabetes Mellitus, Chronic Kidney Disease
A Study to Learn More About Chronic Kidney Disease (CKD) in Patients With Type 2 Diabetes Mellitus (T2DM)
In this observational study, data from the recent past of patients with type 2 diabetes mellitus and chronic kidney disease will be studied.
- Trial name
- CKD-T2DM (NCT05004428)
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 336,376 people
- Sponsor
- Bayer
To Determine If Blood Level (NGAL) Could Accurately Early Detect Acute Renal Damage in All Patients Requiring Critical Care
NGAL in Prediction of AKI and Patient Outcomes
This single-center prospective non-randomized observational research included 120 critically ill persons, at Sohag University hospital's critical care unit.
- Trial name
- NGAL AKI (NCT06691607)
- Testing
- Serum NGAL level
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Sohag University
Acute Kidney Injury
Algorithm for Oliguria in Septic Shock
Acute Kidney Injury (AKI) develops in 88% to 30% of critically ill patients admitted to an intensive care unit and is a strong predictor of mortality.Therefore any management strategy that prevents progression of renal risk to…
- Trial name
- AMOSS (NCT02338895)
- Testing
- Ultrasound
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Chronic Renal Failure
Open Label Trial to Establish the Equivalence Between ANDY-Disc® and Ultrabag® in Patients on CAPD.
Apart from haemodialysis, continuous ambulatory peritoneal dialysis (CAPD) is another effective therapy for end stage renal disease (ESRD).
- Trial name
- NCT00255619
- Testing
- Baxter's UltraBag® and FMC Andy·Disc®
- Where
- 6 sites in Malaysia
- Volunteers
- 264 people
- Sponsor
- Ministry of Health, Malaysia
Chronic Kidney Disease
Empowering Patients On Choices for Renal Replacement Therapy (Aim 1)
The EPOCH-RRT study seeks to fill knowledge gaps by gaining more understanding of chronic kidney disease (CKD) patients' priorities; assessing the comparative benefits of hemodialysis (HD) versus peritoneal dialysis (PD), with…
- Trial name
- EPOCH-RRT (NCT01952600)
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- Arbor Research Collaborative for Health
Chronic Kidney Disease
A Pilot Study for PK/PD Parameter of Colchicine in Chronic Kidney Disease Patient.
A pilot study for PK/PD parameter of colchicine in Chronic kidney disease patient.
- Trial name
- NCT01173107
- Testing
- colchicine
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Anemia of Chronic Kidney Disease
To Evaluate the Efficacy of Three Times Weekly (TIW) Vadadustat Compared to Standard of Care ESA in Patients With Anemia of CKD Receiving In-Center Hemodialysis
This is a multi-center, randomized (1:1), open-label, active-controlled, pragmatic study of the efficacy of vadadustat administered three times a week compared to standard of care erythropoiesis-stimulating agent for the…
- Trial name
- NCT06901505
- Testing
- Erythropoiesis-Stimulating Agent (ESA), Vadadustat
- Where
- 18 sites in United States
- Volunteers
- 353 people
- Sponsor
- Akebia Therapeutics
Acute Renal Failure
Assessment of Metabolic Response in Critically Ill Patients With Acute Renal Failure
We hypothesize that a nutritional supplementation with higher than standard protein content (2.0 gm/Kg/day vs 1.4 gm/Kg/day) will result in improved whole-body net protein balance when administered to critically ill patients with…
- Trial name
- NCT00179166
- Testing
- TPN nutritional supplement
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Vanderbilt University
Chronic Kidney Diseases
The Renal Protective Effects of Remote Ischemic Preconditioning in Patients With Chronic Kidney Disease
The incidence of Chronic kidney disease (CKD) is showing an upward trend, but the therapeutic effect of treatment is limited. Remote ischemic conditioning (RIC) has the potential to safeguard remote organs via the repeated…
- Trial name
- NCT06501222
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Yuanjun Yang
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.