Clinical trials: Renal Infarction
Coronary Artery Disease, Myocardial Infarction
Aspirin Response in High Risk Patients With Coronary Artery Disease
Previous studies indicate that patients with cardiovascular disease have a variable response to aspirin. Despite treatment with aspirin a large number of patients suffer a myocardial infarction.
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Diabetes Mellitus, Renal Insufficiency, Chronic
- Trial name
- NCT01383304
- Where
- Denmark
- Volunteers
- 906 people
- Sponsor
- University of Aarhus
Death, Postoperative Complications
Study to Determine the Impact of Intraoperative Blood Pressure Management on Postoperative Outcomes (MAP-ALIVE)
The purpose of this study is to determine 1. whether intraoperative hypotension or hypertension is independently associated with postoperative mortality and morbidity 2.
- Conditions
- Death, Postoperative Complications, Myocardial Infarction, Stroke
- Trial name
- MAP-ALIVE (NCT02019342)
- Testing
- FACE quality improvement initiative (see below), Pre-quality improvement initiative
- Where
- 2 sites in United States
- Sponsor
- Washington University School of Medicine
Myocardial Infarction, Kidney Function
Renal Acute MI Study
The purpose of this study is to determine if a sizable myocardial infarction (heart attack) results in negative changes to renal structure and function (i.e. has a negative impact on the kidneys).
- Trial name
- NCT01580566
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Monash University
Multiple Myeloma
A Safety and Efficacy Study of Revlimid® 5 mg Capsules in Patients With Relapsed or Refractory Multiple Myeloma Who Have Received Long-term Treatment With it Under the Actual Condition of Use
To understand the safety and efficacy of Revlimid® 5 mg Capsules (hereinafter referred to as Revlimid) in patients with "relapsed or refractory multiple myeloma" (hereinafter referred to as "relapsed or refractory MM") who have…
- Trial name
- NCT02922543
- Where
- Japan
- Volunteers
- 361 people
- Sponsor
- Celgene
Renal Replacement Therapy, Renal Dialysis
A Clinical Trial of IntensiVE Dialysis
This study will assess clinical outcomes of extended weekly hours of haemodialysis (>= 24 hours per week) compared with standard hours of haemodialysis (<=18 hours/week) in people with ESKD.
- Conditions
- Renal Replacement Therapy, Renal Dialysis, End Stage Kidney Disease, End Stage Renal Disease
- Trial name
- ACTIVE (NCT00649298)
- Testing
- haemodialysis
- Where
- 40 sites in Australia, Canada and 2 more
- Volunteers
- 200 people
- Sponsor
- The George Institute
Leukodystrophy, White Matter Disease
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies
Leukodystrophies, and other heritable disorders of the white matter of the brain, were previously resistant to genetic characterization, largely due to the extreme genetic heterogeneity of molecular causes.
- Conditions
- Leukodystrophy, White Matter Disease, 4H Syndrome, Adrenoleukodystrophy
- Trial name
- NCT02699190
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Children's Hospital of Philadelphia
Myocardial Infarction, Diabetes Mellitus
Low Dose Ticagrelor Versus Low Dose Prasugrel in Patients With Prior Myocardial Infarction
Taken together the results from DAPT and PEGASUS-TIMI54, it appears that physicians may consider extending beyond 1 year or reinitiating treatment with a thienopyridine or ticagrelor 60mg bid in patients with a prior MI and…
- Conditions
- Myocardial Infarction, Diabetes Mellitus, Coronary Artery Disease, Renal Disease
- Trial name
- ALTIC-2 (NCT03387826)
- Testing
- Ticagrelor 60 mg, Prasugrel 5mg
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- Attikon Hospital
Coronary Disease, Acute Coronary Syndrome
European Survey of Cardiovascular Disease Prevention, Diabetes and Chronic Kidney Disease (EUROASPIRE VI)
The goal of this observational study is to provide a unique European picture of preventive action by cardiologists, other specialists and primary care physicians looking after patients with coronary heart disease (CHD)…
- Conditions
- Coronary Disease, Acute Coronary Syndrome, Unstable Angina, ST Elevation Myocardial Infarction
- Trial name
- EUROASPIRE VI (NCT06495177)
- Where
- Turkey (Türkiye)
- Volunteers
- 8,000 people
- Sponsor
- European Society of Cardiology
Acute Coronary Syndrome
Protective Effect of Early High Dose stATins On Cardiovascular and Renal Events in Acute Coronary Syndrome
Registration of all ACS patients (STEMI and NSTEMI) admitted to the cardiology ward and scheduled for early invasive strategy. The aim is to evaluate the protective effects of early (on admission) high-dose high-potency statin…
- Trial name
- PRATO-ACS (NCT04087200)
- Where
- Italy
- Volunteers
- 2,500 people
- Sponsor
- Centro Cardiopatici Toscani
Cardiogenic Shock, Cardiorenal Syndrome
Levosimendan Infusion in Critically Ill Patients With Cardiogenic Shock
To determine whether Levosimendan infusion in patients with cardiogenic shock and cardiorenal syndrome refractory to standard inotropic therapy, improves hemodynamics and renal function, whilst being safe.
- Conditions
- Cardiogenic Shock, Cardiorenal Syndrome, Acute Kidney Failure
- Trial name
- NCT04917497
- Testing
- Levosimendan
- Volunteers
- 43 people
- Sponsor
- University of Zurich
Acute Kidney Injury, Renal Insufficiency, Chronic
Acute Kidney Injury Genomics and Biomarkers in TAVR Study
In the last decade, transcatheter aortic valve replacement (TAVR) has become an increasingly utilized alternative procedure for replacing a stenotic aortic valve.
- Conditions
- Acute Kidney Injury, Renal Insufficiency, Chronic, Heart Failure, Myocardial Infarction
- Trial name
- NCT02791880
- Testing
- Transcatheter Aortic Valve Replacement
- Where
- 3 sites in United States
- Volunteers
- 61 people
- Sponsor
- University of Texas Southwestern Medical Center
Renal Infarct, Renal Infarction - Venous
Emergency Department Management of Patients With Renal Infarction
The aim of this study is to investigate laboratory parameters from medical records of patients diagnosed with renal infarction in our emergency clinic to establish early diagnostic indicators.
- Conditions
- Renal Infarct, Renal Infarction - Venous, Renal Infarction - Arterial
- Trial name
- NCT06515379
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi
Acute Myocardial Infarction
Copeptin Registry (proCORE) Biomarkers in Cardiology (BIC)-19
Registry of an interventional Study-proved Strategy (BIC-8) using Copeptin and Troponin for the Early Rule-Out of Acute Myocardial Infarction (AMI) in Patients with Suspected Acute Coronary Syndrome (ACS) and a low-to…
- Trial name
- proCORE (NCT02490969)
- Testing
- Routine management observation
- Where
- Germany
- Volunteers
- 2,256 people
- Sponsor
- Charite University, Berlin, Germany
Secondary Hyperparathyroidism, Disorder Related to Renal Transplantation
Morbidity Related to Secondary Hyperparathyroidism After Renal Transplantation
The purpose of the study is to evaluate the long term vascular morbidity and mortality in kidney transplant recipients based on one year post transplant levels of intact parathyroid hormone.
- Trial name
- SHPT-RT (NCT01741064)
- Volunteers
- 257 people
- Sponsor
- Skane University Hospital
Acute Myocardial Infarction
Effect of the Biomarker Copeptin in Managing Patients With Suspected Acute Coronary Syndrome (ACS)
Acute chest pain is commonly known to be the classic symptom of acute myocardial infarction. Of the many patients which visit the Emergency Department because of chest pain, less than half do actually suffer from an acute…
- Trial name
- BiC-8 (NCT01498731)
- Testing
- Discharge home
- Where
- 6 sites in Austria, Germany and 1 more
- Volunteers
- 902 people
- Sponsor
- Charite University, Berlin, Germany
Obstructive Sleep Apnea, Hypertension
Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans
The study has been designed to assess the effect of cyclooxygenase inhibition on blood pressure, cerebral blood flow, ventilation and renal hemodynamics following chronic intermittent hypoxia exposure.
- Conditions
- Obstructive Sleep Apnea, Hypertension, Cardiovascular Diseases, Stroke
- Trial name
- NCT01280006
- Testing
- Intermittent hypoxia, Indomethacin, Celecoxib
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Chronic Kidney Disease, Chronic Renal Failure
Karolinska Cardiorenal Theme-centre and StockholmHeartbank
Chronic kidney disease (CKD) affects 10-18% of the adult population and is becoming recognized as one of the most serious disorders causing increased risk for cardiovascular disease and death.
- Conditions
- Chronic Kidney Disease, Chronic Renal Failure, Acute Coronary Syndrome, Ischemic Heart Disease
- Trial name
- KKT (NCT01204645)
- Where
- Sweden
- Volunteers
- 10,000 people
- Sponsor
- Danderyd Hospital
ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN)
Beyond the Mehran Risk Score: Predictive Value of Total Ischemic Time for Contrast-Induced Nephropathy in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention.
Contrast-Induced Nephropathy (CIN) is a serious complication following primary percutaneous coronary intervention (PCI) in patients presenting with acute ST-segment elevation myocardial infarction (STEMI).
- Conditions
- ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN), Acute Kidney Injury
- Trial name
- NCT07826572
- Testing
- Total Ischemic Time Evaluation
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
HIV-1-infection, Coronary Microvascular Dysfunction
Improving Coronary Vascular Health in Women
Women with HIV have an increased risk of having a myocardial infarction (heart attack) as compared to women without HIV. One of the mechanisms underlying the increased risk of myocardial infarction among women with HIV may…
- Conditions
- HIV-1-infection, Coronary Microvascular Dysfunction, Metabolic Disease
- Trial name
- INFORM_2 (NCT06843902)
- Testing
- Health Education, Subspecialty clinic referral
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Chest Pain
Copeptin and Acute Coronary Syndrome Without ST-segment Elevation
The purpose of this study is to determine whether the combination of copeptine and troponin adds diagnosis information to that provided by troponin alone or the combination of troponin and myoglobin.
- Trial name
- NCT01334645
- Testing
- Copeptin
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Clermont-Ferrand