Clinical trials: Renal Injury, Acute
Acute Kidney Injury, Chronic Kidney Diseases
Impact on Mortality of Screening for Kidney Disease Associated With a Specialized Intervention During Hospitalization in a Territorial Hospital Trust
Kidney disease in its chronic or acute form shares many risk factors for initiation, progression and prognosis with an increase in morbidity and mortality, the length of hospitalization and the cost associated with stages of…
- Trial name
- WARNING KD (NCT05033652)
- Testing
- WARNING KD
- Where
- 3 sites in France
- Volunteers
- 1,179 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Cardiac Diseases, Cardio-pulmonary Bypass
A Monitoring System Based on the Multifactorial Dynamic Perfusion Index to Predict and Prevent the Onset of Postoperative Acute Kidney Injury After Cardiac Surgery, Based on a Dynamic Collection of Hemodynamic and Clinical Parameters During Cardiopulmonary Bypass
This project is based on a predictive alghorithm (Multifactorial Dynamic Perfusion Index-MDPI) already published and covered by a patent.
- Conditions
- Cardiac Diseases, Cardio-pulmonary Bypass, Acute Kidney Injury, Adult Cardiac Surgery
- Trial name
- PEQUOD 2 (NCT06786416)
- Testing
- PEQUOD
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS Policlinico S. Donato
Coronary Artery Bypass Surgery
TEE Monitoring and the Incidence of Postoperative Acute Kidney Injury in Coronary Artery Bypass Grafting
TEE has a definite effect on the evaluation of cardiac structure and function in perioperative cardiac surgery. However, in CABG, previous studies on TEE mainly focused on whether to change the surgical plan rather than improve…
- Trial name
- NCT05139108
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Qianfoshan Hospital
Vancomycin, Staphylococcal Infections
Vancomycin-Associated Acute Kidney Injury: A Cross-Sectional Study From a Multi- Center in China
The objective of this study was to investigate the current situation of vancomycin (VAN)-associated acute kidney injury (VA-AKI) in China and identify the risk factors for VA-AKI, as well as to comprehensively examine the risk…
- Conditions
- Vancomycin, Staphylococcal Infections, Adverse Effect, Acute Kidney Injury
- Trial name
- NCT03456544
- Testing
- Vancomycin
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Peking University First Hospital
Kidney Failure, Acute
Evaluation of Neutrophil Gelatinase-associated Lipocalin (NGAL) in Early and Evolving Acute Kidney Injury
Some patients who undergo cardiovascular surgery requiring cardiopulmonary bypass will develop a kidney injury following their surgery.
- Trial name
- EVOLVE (NCT00445809)
- Where
- 11 sites in United States, Canada
- Volunteers
- 355 people
- Sponsor
- Abbott RDx Cardiometabolic
Acute Kidney Injury Requiring Continuous Renal Replacement Therapy
Low-intensity Versus Medium-intensity Continuous Kidney Replacement Therapy for Critically Ill Patients
This clinical trial aims to investigate whether the low treatment intensity (12 mL/kg/hr, low-dose hemodialysis/filtration) or the medium treatment intensity (25 mL/kg/hr, standard-dose hemodialysis/filtration) is more effective…
- Trial name
- LIMIT (NCT06014801)
- Testing
- Dialysate fluid, Filtration replacement fluid
- Where
- 9 sites in Japan
- Volunteers
- 400 people
- Sponsor
- Jikei University School of Medicine
Critical Illness, Acute Kidney Injury
Development of a Web-based Multicenter Registry on the Use of oXiris Membrane for EBPTs in Critically Ill Patients
The use of extracorporeal blood purification therapies (EBPT) is becoming increasingly widespread worldwide in everyday clinical practice, particularly in the critical care setting.
- Conditions
- Critical Illness, Acute Kidney Injury, Sepsis, Systemic Inflammatory Response Syndrome
- Trial name
- NCT03807414
- Testing
- oXiris
- Where
- 12 sites in Italy
- Volunteers
- 270 people
- Sponsor
- Careggi Hospital
Cardiac Surgery Associated - Acute Kidney Injury, Cardiac Surgery With Cardiopulmonary Bypass
Inhaled Nitric Oxide for Prevention of Postoperative AKI in High-Risk Cardiac Surgery Patients
The goal of this clinical trial is to learn if giving inhaled nitric oxide during heart surgery can prevent acute kidney injury (AKI) in patients who are at high risk of developing this complication.
- Trial name
- NCT07544147
- Testing
- Inhaled Nitric Oxide (iNO)
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Shanghai Zhongshan Hospital
Heart Failure
Non-steroidal Anti-inflammatory Drugs (NSAIDs) and Risk of Acute Kidney Injury in Patients With Heart Failure
The purpose of this study is to evaluate whether non-steroidal anti-inflammatory drugs (NSAIDs) were associated with acute kidney injury (AKI) in patients with heart failure.
- Trial name
- NCT02642081
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Dissection of Thoracic Aorta
Prevention of Acute Kidney Injury by Erythropoietin in Thoracic Aorta Surgery With Hypothermic Cardiac Arrest
During thoracic aortic surgery, hypothermic cardiac arrest causes aortic ischemia and reperfusion (IR) periods, respectively. Aortic ischemia results in an ischemic insult to the lower extremities and successive reperfusion…
- Trial name
- NCT01369732
- Testing
- recombinant human erythropoietin, saline
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Yonsei University
Acute Kidney Injury
Amino Acid Supplementation in Continuous Renal Replacement Therapy
ICU patients treated with continuous renal replacement therapy is recruited prior to start of treatment. Blood samples are drawn and then dialysis start without amino acid supplementation.
- Trial name
- AARRT (NCT06835816)
- Testing
- Amino acid supplementation (Glavamin, Fresenius Kabi)
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska University Hospital
Acute Renal Failure
Clearance of Inflammatory Cytokines During Renal Replacement Therapy Using the EMIC®2 Filter
This study will be conducted in patients with sepsis and acute kidney injury needing renal replacement therapy. The aim is to investigate whether continuous renal replacement therapy with the EMIC®2 filter leads to removal of…
- Trial name
- ClicAKI (NCT03231748)
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Hantavirus Nephropathy, Hantavirus Infection
Hantavirus Nephropathy in North-Eastern France : Severity Risk Factors and Prognostic Tools
Hantaviruses are emerging pathogens responsible for hemorrhagic fever with renal syndrome. Severity risks factors aren't consensual in litterature, mostly related to scandinavian cohorts.
- Trial name
- HANTA-NE (NCT05415904)
- Testing
- HANTA-NE
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Central Hospital, Nancy, France
Acute Kidney Injury, Contrast Media Toxicity
Curcuminoids and Contrast-induced Acute Kidney Injury
The objective of this study was to evaluate the role of curcuminoids in the prevention of CI-AKI in CKD patients.The result of the study was prophylactic administration with curcuminoids in addition to standard treatment reduce…
- Conditions
- Acute Kidney Injury, Contrast Media Toxicity, Curcuminoid, Chronic Kidney Diseases
- Trial name
- NCT04890704
- Testing
- Curcuminoid
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Acute Kidney Injury
Prognosis of Acute Kidney Injury:China Collaborative Study on AKI（CCS-AKI）Study
Acute kidney injury (AKI) is a common clinical syndrome, especially in the hospital patients. AKI is recognized as an important risk factor for incident chronic kidney disease, accelerated progression to end-stage renal…
- Trial name
- NCT03061786
- Where
- China
- Sponsor
- XinLing Liang
Sepsis, Acute Kidney Injury
Identifying Risk Factors for Developing AKI in Sepsis
A study to evaluate the prevalence of Acute Kidney Injury (AKI) in patients with Diabetic Ketoacidosis (DKA) and sepsis using data collected prospectively to a patient registry.
- Conditions
- Sepsis, Acute Kidney Injury, Diabetic Ketoacidosis
- Trial name
- NCT04825639
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Cardiff and Vale University Health Board
Kidney Injury
Acute Kidney Injury in Poly Trauma Patients
The aim of this study is to identify the incidence and the factors associated with acute kidney injury in adult poly trauma patients
- Trial name
- NCT06108765
- Volunteers
- 100 people
- Sponsor
- Assiut University
Acute Kidney Injury
The Effect of Nafamostat Mesilate in Prolonging Filter Patency With Patients on Continuous Renal Replacement Therapy
Continuous renal replacement therapy (CRRT) has been considered as an effective modality for renal replacement therapy in hemodynamically unstable patients within intensive care unit (ICU) except for the necessity of…
- Trial name
- NCT01761994
- Testing
- Anticoagulation with nafamostat mesilate
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Yonsei University
Acute Kidney Injury
The Goal dIrected perFusion Trial in Cardiac Surgery
Previous studies (1-5) have demonstrated that oxygen delivery (DO2) and carbon dioxide production (VCO2) during cardiopulmonary bypass (CPB) are associated with renal outcome in cardiac surgery.
- Trial name
- GIFT (NCT02250131)
- Testing
- Perfusion targeted at oxygen delivery
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- IRCCS Policlinico S. Donato
Acute Kidney Injury
Role of Neuronal Guidance Proteins as Diagnostic Markers for Acute Kidney Injury (AKI)
Acute kidney failure remains one of the most challenging entities to diagnose in clinical medicine, especially in the field of intensive care.
- Trial name
- NEUKID (NCT05924269)
- Volunteers
- 600 people
- Sponsor
- University Hospital Tuebingen
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