Clinical trials: Renal Injury, Acute
Acute Kidney Failure, Chronic Kidney Diseases
Enhancing Fluid Transfer Through the Skin, by Increased Sweat Rate, on Hemodialysis Patients
To demonstrate safety and performance of AquaPass System for improving fluid balance in hemo-dialysis patients, by increasing fluid loss via the skin.
- Trial name
- NCT06358365
- Testing
- The AquaPass System
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- AquaPass Medical Ltd.
Acute Kidney Injury
Impact of Ascorbic Acid in the Prevention of Vancomycin Induced Nephrotoxicty
A Randomized controlled trial aiming to investigate whether ascorbic acid has a role in preventing vancomycin induced nephrotoxicity or not in critically ill patients.
- Trial name
- NCT03921099
- Testing
- Ascorbic Acid
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Acute Kidney Injury
The CIRE Study (CItrate REcirculation Study)
The aim of this study is to determine the effects of AV port reversal (AVPR) on recirculation, clearance, post-filter ionized calcium and subsequently citrate dosing.
- Trial name
- CIRE (NCT02600416)
- Testing
- AV port reversal
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Ziekenhuis Oost-Limburg
Early Ventilator Associated Pneumonia, Acute Brain Injuries
PK/PD Target Attainment of Ceftriaxone for the Prevention of Early Ventilator-associated Pneumonia in Neurologically Injured Patients
Critically ill patients admitted for acute brain injury are exposed to many heath-care associated infections such as ventilator associated pneumoniae (VAP).
- Trial name
- NeuroPKVAP (NCT07450404)
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Central Hospital, Nancy, France
Acute Kidney Injury, Hypoxic-Ischemic Encephalopathy
PK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia
A phase 1 study investigating the tolerability and pharmacokinetics of caffeine citrate in neonates with hypoxic ischemic encephalopathy receiving therapeutic hypothermia.
- Conditions
- Acute Kidney Injury, Hypoxic-Ischemic Encephalopathy, Caffeine
- Trial name
- NCT05295784
- Testing
- Caffeine citrate
- Where
- 2 sites in United States
- Sponsor
- University of Arkansas
Kidney Failure, Acute
Uremic Toxins of Patients With Acute Kidney Failure
Determination of the concentration of uremic toxins of sepsis patients with or without acute kidney failure compared to the concentrations of uremic toxins of chronically uremic patients
- Trial name
- NCT00148044
- Testing
- Blood sampling for determination of uremic toxins
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Acute Kidney Injury
Study to Prevent Acute Kidney Injury After Cardiac Surgery Involving Cardiopulmonary Bypass
The objective of the study is to assess the safety and efficacy of ANG-3777 in preventing AKI compared to placebo when administered to patients at risk for developing acute kidney injury (AKI) following cardiac surgical…
- Trial name
- NCT02771509
- Testing
- ANG-3777
- Where
- 40 sites in United States, Brazil and 2 more
- Volunteers
- 275 people
- Sponsor
- Angion Biomedica Corp
Cancer, Cisplatin Adverse Reaction
Effects of DPP4 Inhibitor on Cisplatin Induced Acute Kidney Injury
Cisplatin is a potent chemotherapeutic agent, however, its nephrotoxicity manifested by acute kidney injury (AKI) often limits applicability.
- Trial name
- NCT02250872
- Testing
- Gemigliptin, Cisplatin
- Where
- South Korea
- Volunteers
- 182 people
- Sponsor
- Seoul National University Bundang Hospital
Alzheimer Disease, Late Onset, Stroke
Explore the Sharing Model Intervene to Improve the Knowledge, Attitudes, Service Intentions and Service Start-up Effects of the Eight Major Non-cancer Disease End-stage Caregivers on Well-being and Palliative Care
Since September 1st, 2009, Taiwan has begun to pay attention to the care of patients with organ failure, dementia and the elderly, and brought eight of non-cancer terminal patients into health insurance subsidies to implement the…
- Conditions
- Alzheimer Disease, Late Onset, Stroke, Heart Failure, Pulmonary Disease, Chronic Obstructive
- Trial name
- NCT05407272
- Testing
- Health Education Manual, manual
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wen-Shiou Pan
COVID19, Acute Renal Failure
The Effect of the Severity of COVID-19 Disease on the Incidence of Acute Renal Failure in ICU
Aim of the study is to determinate the frequency of acute renal failure in COVID-19 patients, its relationship with the severity of COVID-19 disease in ICU, and the ability to take precautions against these factors.
- Trial name
- NCT04799600
- Testing
- BRESCİA-COVİD Respiratory Severity Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Cardiac Surgery, Coronary Artery Bypass
An Trial of Two Dosing Regimens of AP214 for the Prevention of Kidney Injury in Patients Undergoing Cardiac Surgery
This study investigates the effect of two dose-levels of AP214 on the prevention of (acute) kidney injury after cardiac surgery.
- Conditions
- Cardiac Surgery, Coronary Artery Bypass, Aortic Aneurysm, Valve Surgery
- Trial name
- NCT01256372
- Testing
- AP214
- Where
- Denmark
- Volunteers
- 77 people
- Sponsor
- Action Pharma A/S
Acute Renal Failure
Uremic Toxins in the Intensive Care Units (ICU): Patients With Lactate Acidosis
Study of the kinetics of uremic toxins in the ICU patients with acute renal failure, in order to optimize the dialysis dose: patients with lactate acidosis.
- Trial name
- NCT00752453
- Testing
- Dialysis during 4 hours, Dialysis during 6 hours, Dialysis during 8 hours
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- University Hospital, Ghent
Decreased Vascular Flow to Kidneys
Validation of Transesophageal Echocardiography (TEE) to Measure Renal Resistive Index and to Predict Renal Injury
The study doctors are trying to determine if the TEE measurements from your stomach are helpful in measuring the blood flow to the kidneys.
- Trial name
- NCT01151774
- Where
- United States
- Sponsor
- University of Medicine and Dentistry of New Jersey
Abdomen, Acute, Myocardial Injury
MINS, AKI and Pulmonary Pathology in Patients Undergoing Acute Abdominal Surgery
Explorative study to investigate potential predictors of myocardial injury, acute kidney injury and pulmonary disorder after acute high-risk abdominal surgery.
- Conditions
- Abdomen, Acute, Myocardial Injury, Acute Kidney Injury, Pulmonary Disease
- Trial name
- NCT04681508
- Testing
- Chest CT without contrast enhancement and chest X-ray
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Nordsjaellands Hospital
Critical Illness, Sepsis
Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial
This is a prospective, unmasked, randomized, multicenter clinical trial evaluating the impact of point-of-care large language model (LLM)-based decision support on diagnostic accuracy and clinical outcomes in adult medical…
- Conditions
- Critical Illness, Sepsis, Acute Respiratory Failure (ARF), Multi-organ Failure
- Trial name
- POC-AI-ICU (NCT07293078)
- Testing
- Point-of-care large language model decision support (ChatGPT-5)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- MetroWest Artificial Intelligence Research Workgroup
AKI (Acute Kidney Injury) Due to Trauma
Acute Kidney Injury and Ultra-endurance Running
This study aims to understand how participating in the Western States Endurance Run (WSER), a 100-mile ultramarathon, affects kidney health.
- Trial name
- NCT07519408
- Testing
- Sodium Bicarbonate (NaHCO3)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Cardiac Surgery
Nicotinamide Mononucleotide in Patients Undergoing Cardiac Surgery
The investigators will perform a phase 2a, randomized, double-blind, placebo-controlled clinical trial in adult patients undergoing elective cardiac surgery to investigate the effects of oral nicotinamide mononucleotide (NMN)…
- Trial name
- NCT07013591
- Testing
- MIB-626
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Brigham and Women's Hospital
Critically Ill, Nutrition Disorders
Early Goal Nutrition Therapy Guided by Indirect Calorimetry and Nitrogen Balance Among Critically Ill Patients With Acute Kidney Injury (ENGINE Study)
The goal of this clinical trial is to investigate the effects of nutrition therapy guided by indirect calorimetry and nitrogen balance among critically ill patients with acute kidney injury.
- Conditions
- Critically Ill, Nutrition Disorders, Acute Kidney Injury
- Trial name
- ENGINE (NCT06238674)
- Testing
- indirect calorimetry and nitrogen balance, Indirect calorimetry (Standard care nutrition arm)
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Wankawee Jeerangsapasuk
Hypotension During Dialysis, Fluid Overload
Fluid Mobilization in Hospitalized Patients With Acute Kidney Injury
Hospitalized patients often suffer from an acute shutdown of kidney function secondary to infections, use of antibiotics, or use of intravenous contrast agents.
- Trial name
- NCT04522635
- Testing
- (100 ml of Albumin 25%)
- Volunteers
- 65 people
- Sponsor
- University of California, San Diego
Pediatric Kidney Disease, Acute Kidney Injury
Registry for HF20 for Pediatric CRRT Under Emergency Use Authorization
Historically, innovations for acute kidney injury (AKI) and continuous renal replacement therapy (CRRT) have centered around an adult population.
- Trial name
- NCT04836026
- Testing
- HF20™
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
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