Clinical trials: Renal Injury, Acute
Kidney Failure
Far Infrared Treatment for Kidney Diseases
Renal failure or kidney failure is a situation in which the kidneys fail to function adequately. It is divided into acute and chronic forms; either form may be due to a large number of other medical problems.
- Trial name
- NCT00599391
- Testing
- Far Infrared Radiation (5μm to 20μm wavelength)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- GAAD Medical Research Institute Inc.
Cardiac Surgery, Acute Kidney Injury
Acute Normovolemic Hemodilution in Complex Cardiac Surgery
Postoperative bleeding in cardiac surgery is a frequent complication, and cardiac surgery utilizes 15-20% of the national blood supply. Packed red blood cells (pRBCs) are associated with worse short and long term outcomes.
- Conditions
- Cardiac Surgery, Acute Kidney Injury, Congenital Heart Disease, Aortic Surgery
- Trial name
- ANH (NCT05049590)
- Testing
- Acute normovolemic hemodilution (ANH)
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of California, Los Angeles
Cardiogenic Shock, Cardiorenal Syndrome
Levosimendan Infusion in Critically Ill Patients With Cardiogenic Shock
To determine whether Levosimendan infusion in patients with cardiogenic shock and cardiorenal syndrome refractory to standard inotropic therapy, improves hemodynamics and renal function, whilst being safe.
- Conditions
- Cardiogenic Shock, Cardiorenal Syndrome, Acute Kidney Failure
- Trial name
- NCT04917497
- Testing
- Levosimendan
- Volunteers
- 43 people
- Sponsor
- University of Zurich
Coronary Artery Disease, Acute Kidney Injury
Endothelial Glycocalyx Damage in Acute Kidney Injury
Abstract Significance: Cardiac surgery-associated acute kidney injury (CSA-AKI) is common and has serious immediate and long-term sequelae.
- Trial name
- NCT05471583
- Testing
- Main group
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- King's College London
Heart Failure, Kidney Injury
Optimization of the Treatment of Acute HF by a Non Invasive Cardiac System-a Randomized Control Trial
The aim of this trial is to compare the efficacy of NICaS-directed treatment strategy to the common treatment strategy (based on clinical judgment) on morbidity and mortality in patients with decompensated congestive heart…
- Trial name
- HFNICAS (NCT02126254)
- Testing
- Hemodynamic group
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Congenital Heart Disease, Cardiopulmonary Bypass
Acetaminophen for Oxidative Stress After Cardiopulmonary Bypass
The current proposal tests the central hypothesis that acetaminophen will attenuate the oxidative stress response associated with cardiopulmonary bypass (CPB)-induced hemolysis in children undergoing cardiac surgery.
- Trial name
- NCT01228305
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center
Acute Kidney Injury
Standard vs. Accelerated Initiation of RRT in Acute Kidney Injury (STARRT-AKI: Principal Trial)
The objectives of this trial are to determine whether, in critically ill patients with severe acute kidney injury (AKI), randomization to accelerated initiation of renal replacement therapy (RRT), compared to standard initiation…
- Trial name
- NCT02568722
- Testing
- Standard RRT initiation, Accelerated RRT initiation
- Where
- 105 sites in United States, Australia and 13 more
- Volunteers
- 3,019 people
- Sponsor
- Unity Health Toronto
AKI - Acute Kidney Injury, Cardiac Surgical Procedures
rhBNP for Prevention of Cardiac Surgery-Associated Acute Kidney Injury (CSA-AKI)
Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common and serious perioperative complication, independently associated with prolonged hospitalization, increased mortality, and progression to chronic kidney disease.
- Conditions
- AKI - Acute Kidney Injury, Cardiac Surgical Procedures, Cardiopulmonary Bypass
- Trial name
- PROTECT-CS (NCT07617675)
- Testing
- Recombinant Human Brain Natriuretic Peptide (rhBNP)
- Where
- China
- Volunteers
- 694 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronavirus Infection, Covid19
Renal Biomarkers in AKI and COVID-19
Severe pneumoniae related to Coronavirus Disease (COVID-19), had a high in-hospital mortality; this condition are worst in subjects with acute kidney disease (AKI); conditioning increased mortality, days of assisted mechanical…
- Conditions
- Coronavirus Infection, Covid19, SARS (Severe Acute Respiratory Syndrome), AKI
- Trial name
- NCT04517630
- Testing
- urinary NGAL, TIMP-2, IGFBP7, IL-6, viral load and metabolomic
- Where
- Mexico
- Volunteers
- 51 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
Acute Kidney Injury
Drug-induced Kidney Injury Model
To establish the prediction model of renal dysfunction in patients with drug-induced renal injury and study the prognosis of different drug treatments
- Trial name
- NCT06939387
- Testing
- Observational study, no intervention
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Zhejiang Provincial People's Hospital
Acute Kidney Injury
Heme Arginate in Cardiac Surgery Patients
A recent analysis of over 4500 cardiac surgical patients at the Royal Infirmary of Edinburgh has confirmed that acute kidney injury (AKI) is not only a relatively common post-operative complication but is associated with…
- Trial name
- HACS (NCT02142699)
- Testing
- Heme arginate
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Edinburgh
Septic Shock, Acute Kidney Injury
MCO Membrane Efficiency in Septic Shock Patients
This is a monocentre randomized pilot study. All patients received two consecutive RRT: CVVHD with MCO filter (Ultraflux® EMiC®2) and post-Continuous Veno-Venous Hemodiafiltration (CVVHDF) with HFF(AV1000S®) in a controlled…
- Trial name
- NCT04834921
- Testing
- Ultraflux® EMiC®2
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fiorenza Ferrari
Acute Kidney Failure
Prostacyclin's Effect on Platelet Responsiveness
The researchers investigated the influence of a prostacyclin analogue (PGIA) versus unfractionated heparin (UFH) on ex vivo platelet function, during continuous venovenous hemodiafiltration.
- Trial name
- NCT00890214
- Testing
- prostacyclin, heparin
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Catholic University of the Sacred Heart
Acute Kidney Injury
A Study of Facilitators and Barriers to Improve Acute Kidney Injury in Children Through Mobile Health Intervention
The purpose of this study is to improve patient-centered care for acute kidney injury (AKI) in order to decrease the adverse health outcomes associated with this common condition.
- Trial name
- NCT04403633
- Testing
- mobile health educational tool
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
Acute Renal Failure (ARF), Acute Tubular Necrosis
Use of QRX3 for Acute Tubular Necrosis Type of Renal Failure in Hospitalized Patients ( QRX-3 in ARF)
Use of QRX-3 in hospitalized patients with pediatric and adult patients with acute tubular necrosis renal failure
- Trial name
- QRX3 in ARF (NCT07161843)
- Testing
- QRX-3
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Ebima Clifford Okundaye
Sepsis
Bioimpedance Analysis in Septic Intensive Care Unit (ICU) Patients
Patients with severe infections initially require large amounts of fluid as part of resuscitation. Later on however, problems may arise from excess fluid such as increased time on a ventilator and kidney damage.
- Trial name
- BIOVISION (NCT01379404)
- Testing
- Bioelectric Impedance Analysis
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Pyelonephritis, Prognostic
Factors and Prognosis of Obstructive Pyelonephritis Patients
Acute obstructive pyelonephritis is a condition with a high risk of complications and may require admission to the intensive care unit.
- Trial name
- PYELO-OBS (NCT06299215)
- Where
- France
- Volunteers
- 575 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Kidney Injury
Perioperative Transcutaneous Fluorescence Detection of GFR Trajectory for the Early Prediction and Diagnosis of CSA-AKI.
brief summary：The goal of this observational study is to evaluate the value of perioperative transcutaneous fluorescence glomerular filtration rate (GFR) monitoring for the early prediction and diagnosis of cardiac…
- Trial name
- NCT07749417
- Where
- China
- Volunteers
- 436 people
- Sponsor
- China National Center for Cardiovascular Diseases
Perioperative Complications, Perioperative/Postoperative Complications
Perioperative Database of Chinese Elderly Patients
The investigators aim to establish a prospective database of perioperative elderly patients from multiple regions and centers. Collected data involves postoperative complications of the central nervous system, cardiovascular…
- Conditions
- Perioperative Complications, Perioperative/Postoperative Complications, Perioperative Adverse Events
- Trial name
- PDCEP (NCT04911530)
- Testing
- no intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Chinese PLA General Hospital
Acute Kidney Injuries
C-reactive Protein & Albumin Ratio IN AKI
Acute pancreatitis (AP), defined as acute inflammation of the pancreas, it's one of the most common diseases of the gastrointestinal tract leading to hospital admission.(1) The global incidence of AP is reported between 20 and 40…
- Trial name
- NCT07335757
- Testing
- C-reactive protein to albumin ratio
- Volunteers
- 150 people
- Sponsor
- Assiut University
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