Clinical trials: Renal Injury, Acute
Sepsis, Acute Kidney Injury Due to Sepsis
Renin Angiotensin Aldosterone System In Septic Kids
Prospective observational cohort study; pediatric sepsis vs. healthy pediatric subjects and pediatric sepsis with acute kidney injury (AKI) vs without AKI.
- Conditions
- Sepsis, Acute Kidney Injury Due to Sepsis, Acute Kidney Injury (Nontraumatic)
- Trial name
- RISK (NCT06295393)
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Femur Fracture, Acute Renal Failure
Preventive Norepinephrine Infusion During Surgery for Upper Femoral Fracture and Post-operative Acute Renal Failure
The fracture of the upper extremity of the femur (FESF) is one of the most common fractures in traumatology. In France, FESF affects more than 65,000 individuals per year and could involve up to 150,000 people per year by 2050…
- Trial name
- NORAKI (NCT05566132)
- Where
- France
- Volunteers
- 676 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Acute Kidney Injury, Outcomes
The Effect of Automated Electronic Alert for Acute Kidney Injury on the Outcomes of Hospitalized Patients
Acute kidney injury (AKI) is a common disease, but diagnosis is usually delayed or missed in hospitalized patients. The automated electronic alert for AKI may help to improve the outcomes of these patients through identifying all…
- Conditions
- Acute Kidney Injury, Outcomes, Early Diagnosis
- Trial name
- NCT03736304
- Testing
- AKI alert, Usual care
- Where
- China
- Volunteers
- 4,536 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Acute Renal Failure
Brief Title:Effect of a Preoperative Calorie Restriction on Renal Function After Cardiac Surgery
The aim of this study is to assess the effect of a diet prior to cardiac surgery on the common postoperative decline of renal function. Until now, there is no known drug or procedure to preserve the kidneys from this impairment.
- Trial name
- CR_KCH (NCT01534364)
- Testing
- calorie restriction
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- University of Cologne
Renal Transplant, Renin-Angiotensin System
Renal Transplant Injury and the Renin-Angiotensin System in Kids (RETASK)
In pediatric kidney transplant patients, rejection, medication toxicity and ischemia cause early and chronic renal allograft injury, which reduces graft lifespan and patient survival.
- Conditions
- Renal Transplant, Renin-Angiotensin System, Rejection Acute Renal, Rejection Chronic Renal
- Trial name
- RETASK (NCT03317925)
- Testing
- Renal Transplantation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Wake Forest University Health Sciences
Liver Transplantation
Association of Genetic Polymorphism and Acute Kidney Injury After Liver Transplantation
Some of the liver transplantation recipients experience postoperative acute kidney injury due to various causes including genetic factors.
- Trial name
- NCT02489474
- Where
- South Korea
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Acute Kidney Injury
Differential Adaptation of Renal Function in Intense Physical Exercise
In recent years there has been a significant increase in the number of participants in high intensity and duration sports events.
- Trial name
- NCT04929418
- Testing
- 10 km continuous running, 1.5 km continuous swimming
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Clínico Universitario de Valladolid
Cardio-Renal Syndrome, Coronary Angiography
Risk Factors and Prognosis of Adverse Cardiovascular and Kidney Events After Coronary Intervention
As a single center, retrospective observation study in Guangdong Institute of Cardiovascular Diseases, this study included the main study population of patients who underwent coronary angiography and / or coronary intervention…
- Conditions
- Cardio-Renal Syndrome, Coronary Angiography, Coronary Artery Disease, Kidney Diseases
- Trial name
- NCT04407936
- Where
- China
- Volunteers
- 88,938 people
- Sponsor
- Guangdong Provincial People's Hospital
Acute Kidney Injury
Neutral Endopeptidase for Early Detection of Acute Kidney Injury After Cardiac Surgery
The investigators want to investigate if the urinary biomarker neprilysin can identify cardiac surgical patients suffering from postoperative AKI within 24 hours.
- Trial name
- NEPAKI-CS (NCT03854825)
- Testing
- Cardiac surgery
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Nephrectomy, Acute Kidney Injury
Novel Biomarkers and Postoperative Kidney Injury in Radical Nephrectomy
The incidence of acute kidney injury (AKI) after radical nephrectomy exceeds 40%. Currently, the KDIGO criteria are the recognized diagnostic standard for AKI.
- Conditions
- Nephrectomy, Acute Kidney Injury, Biomarker
- Trial name
- NCT07088874
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University First Hospital
Coronary Artery Bypass, Off-Pump, Intraoperative Hypotension
Targeted Blood-pressure Management and Acute Kidney Injury After Coronary Artery Bypass Surgery
Acute renal injury (AKI) is a common complication after cardiac surgery and is associated with worse outcomes. It is now realized that intraoperative hypotension is an important risk factor for the development of AKI.
- Conditions
- Coronary Artery Bypass, Off-Pump, Intraoperative Hypotension, Acute Kidney Injury, Preventive Medicine
- Trial name
- NCT03629418
- Testing
- Targeted blood-pressure management, Routine blood-pressure management
- Where
- China
- Volunteers
- 612 people
- Sponsor
- Peking University First Hospital
Congenital Heart Disease
Urine and Serum Biomarkers for Early Detection of Acute Kidney Injury
The purpose of this study is to find out whether a combination of new urine tests and blood tests can show kidney injury in its early stages, before kidney failure sets in.
- Trial name
- NCT01531985
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Acute Kidney Injury
Safety and Efficacy of a Selective Cytopheretic Device (SCD) in Pediatric Patients With Acute Kidney Injury (AKI).
The SCD (Selective Cytopheretic Device) is an extracorporeal device used as an adjunct to renal replacement therapy (RRT) to improve the outcomes of pediatric patients with acute kidney injury (AKI).
- Trial name
- SCD-PED-01 (NCT02820350)
- Testing
- SCD-F40
- Where
- 4 sites in United States
- Volunteers
- 19 people
- Sponsor
- CytoPherx, Inc
Acute Kidney Injury
The Effect of Sodium Bicarbonate on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery
The purpose of study is to test whether perioperative sodium bicarbonate infusion can prevent acute kidney injury following open heart surgery in infective endocarditis patients.
- Trial name
- NCT01920126
- Testing
- sodium bicarbonate, Saline
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Yonsei University
Acute Kidney Injury (Nontraumatic), Critical Illness
Impact of CRRT on Serum Carnitine and Micronutrient Levels
This study aims to investigate the changes in blood levels of micronutrients and carnitine in critically ill patients with Acute Kidney Injury (AKI) who are undergoing Continuous Renal Replacement Therapy (CRRT).
- Trial name
- NCT07467889
- Testing
- Continuous Renal Replacement Therapy (CRRT), Standard of Care (Non-CRRT Management)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Gulhane Training and Research Hospital
Acute Kidney Injury
Tunneled Dialysis Catheters Versus Non-tunneled Dialysis Catheters as First-line for Renal Replacement Therapy in the ICU
The investigators propose a randomized controlled trial to examine whether tunneled dialysis catheters should be first-line for acute kidney injury requiring renal replacement therapy (AKI-RRT) in the critical care setting…
- Trial name
- BACKDOOR (NCT03496935)
- Testing
- Tunneled versus non-tunneled dialysis catheter insertion
- Volunteers
- 102 people
- Sponsor
- Brigham and Women's Hospital
Cirrhosis, Liver, Acute-On-Chronic Liver Failure
Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Refractory Ascites
Point-of-care echocardiography (POC-Echo) is used to determine left ventricular systolic and diastolic dysfunction (LVDD), inferior vena cava (IVC) dynamics and volume status in cirrhosis and Acute-on-chronic liver failure ACLF…
- Conditions
- Cirrhosis, Liver, Acute-On-Chronic Liver Failure, Refractory Ascites, Ascites
- Trial name
- NCT05700708
- Testing
- Echocardiographic assessment
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Acute Renal Failure
A New Way to Detect Acute Kidney Injury
Acute renal failure after cardiac surgery is a common postoperative complication, affecting approximately 20% of patients. It is associated with an increase in short-term mortality and an increase in hospital stay; but is also…
- Trial name
- VEX-CARDS (NCT07198906)
- Testing
- Determination of VEXUS score and onset of chronic renal failure
- Where
- France
- Sponsor
- University Hospital, Rouen
Acute Kidney Injury, Cirrhosis
NEPH-ROSIS (NEPHrology in CirRhOSIS) Pilot Trial: A Trial to Treat Acute Kidney Injury Among Hospitalized Cirrhosis Patients
The goal of this pilot, randomized, single-blind clinical trial is to estimate the effect size of a high and low mean arterial pressure (MAP)-target algorithm among cirrhosis patients hospitalized with acute kidney injury.
- Conditions
- Acute Kidney Injury, Cirrhosis, Portal Hypertension, Hepatorenal Syndrome
- Trial name
- NEPH-ROSIS (NCT06000748)
- Testing
- MAP-Target Algorithm
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of California, San Francisco
Intraoperative Hypotension, Intraoperative Complications
Comparison of Conventional Fluid Management Protocol With Targeted Pleth Variability Index (PVI) Monitoring Protocol During Total Abdominal Hysterectomy and Bilateral Salpingooferectomy Operation
This study aims to compare the volume management methods performed by using conventional method and PVI monitoring in intraoperative fluid treatment during bilateral salpingo-oophorectomy and total hysterectomy operation.
- Conditions
- Intraoperative Hypotension, Intraoperative Complications, Hypervolemia, Acute Renal Failure
- Trial name
- NCT04775576
- Testing
- Pleth Variability Index, Conventional fluid theraphy, Anesthesia method
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
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