Clinical trials: Renal Injury, Acute
Acute Kidney Injury in Patients With Liver Cirrhosis
Acute Kidney Injury in Patients With Liver Cirrhosis
In our locality, limited studies have discussed AKI in patients with liver cirrhosis and its outcome, therefore we aim to highlight the incidence, patterns, risk factors, and outcomes of acute kidney injury in patients with liver…
- Trial name
- NCT06343389
- Testing
- serum creatinine
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Sohag University
Acute Kidney Injury, Fluid Overload
Forced Fluid Removal in High Risk Acute Kidney Injury
The objective of this pilot trial is to assess the feasibility of forced fluid removal in patients admitted to the intensive care unit (ICU) with high-risk AKI and severe fluid overload.
- Conditions
- Acute Kidney Injury, Fluid Overload, Critical Illness
- Trial name
- FFAKI (NCT02458157)
- Testing
- Furosemide (Furix), Continuous renal replacement therapy (CRRT), Resuscitation
- Where
- 3 sites in Denmark
- Volunteers
- 21 people
- Sponsor
- Nordsjaellands Hospital
Contrast-Associated Acute Kidney Injury, Acute Kidney Injury
Contrast Volume as a Predictor of Kidney Injury Following Contrast-Enhanced CT
Iodinated contrast dye used during computed tomography (CT) scans can sometimes cause kidney stress or damage, known as contrast-associated acute kidney injury (CA-AKI).
- Conditions
- Contrast-Associated Acute Kidney Injury, Acute Kidney Injury, Contrast-Induced Nephropathy, Acute Renal Failure
- Trial name
- NCT07813819
- Volunteers
- 1,112 people
- Sponsor
- Assiut University
Acute Kidney Injury
To Examine Whether Urinary Partial Oxygen Pressure Measurements Are Indicative of the Postoperative Occurrence of Acute Kidney Injury (AKI) in Individuals Who Have Undergone Liver Transplantation
Postoperative acute kidney injury (AKI) is a frequent occurrence among liver transplant recipients and results in considerable mortality and morbidity.
- Trial name
- NCT06121167
- Testing
- urinary partial oxygen pressure
- Volunteers
- 98 people
- Sponsor
- Inonu University
Acute Kidney Injury, Septic Shock
Macro and Micro Haemodynamic Responses to Shock in the Renal and Systemic - MICROSHOCK - RENAL
An observational study of the state of the renal and systemic circulations in patients with early septic shock. Both macro and microvascular parameters will be assessed using echocardiography, sublingual incident dark field…
- Trial name
- NCT03713307
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- King's College London
Diabetes Mellitus, Chronic Kidney Disease
Rosuvastatin Prevent Contrast Induced Acute Kidney Injury in Patients With Diabetes
The number of cardiac angiography and percutaneous coronary interventions (PCI) has increased steadily in recent years. This has resulted in the increasing incidence of contrast-induced acute kidney injury (CIAKI).
- Trial name
- TRACK-D (NCT00786136)
- Testing
- rosuvastatin
- Where
- 53 sites in China
- Volunteers
- 2,998 people
- Sponsor
- Shenyang Northern Hospital
Contrast Induced Acute Kidney Injury
Monitoring Renal Blood Flow With Contrast Enhanced Ultrasound During Coronary Angiogram
Contrast induced nephropathy (CN) is a common cause of acute kidney injury and is associated with increased morbidity and mortality and healthcare cost.
- Trial name
- NCT01544036
- Testing
- perflutren
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Virginia
Acute Kidney Injury
PK and PD of Sequential Multiple Ascending, Repeat Doses of Oral CXA-10 in Healthy Obese Male Subjects
The main purpose of this trial is to demonstrate the safety, tolerability and pharmacokinetics (PK) of CXA-10 and its metabolite(s) administered as multiple ascending oral doses over 14 days to healthy obese male volunteers.
- Trial name
- NCT02460146
- Testing
- CXA-10
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Complexa, Inc.
Covid19, Acute Kidney Injury
Urine Alkalinisation in COVID-19
Since the outbreak of coronavirus disease 2019 (COVID-19), more than 100,000 patients have died in the United Kingdom. Acute kidney injury is common in critically ill patients with COVID-19.
- Trial name
- NCT04806061
- Testing
- Sodium bicarbonate, standard care
- Where
- 2 sites in United Kingdom
- Volunteers
- 80 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Renal Impairment, Limb Ischemia, Critical
Ultra-low Dose Contrast for Endovascular Procedures
The purpose of this protocol is to study the safety and feasibility of using ultra-low dose iodinated contrast agent for infrainguinal endovascular revascularization procedures in patients with chronic limb-threatening lower limb…
- Trial name
- ULTRA-LOW (NCT06835127)
- Testing
- Infrainguinal peripheral endovascular revascularization
- Where
- Greece
- Volunteers
- 18 people
- Sponsor
- Attikon Hospital
Liver Cancer, Adult
Risk Stratification and Proactive Nursing Intervention for Acute Kidney Injury Following Interventional Therapy in Patients With Liver Cancer
This study focuses on the early identification and precision prevention of acute kidney injury (AKI) following interventional therapy in patients with liver cancer.
- Trial name
- NCT07681817
- Testing
- Risk-stratified active nursing intervention group, Standard care (usual post-interventional nursing care)
- Volunteers
- 200 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Acute Kidney Injury (AKI)
Precision-Medicine Diagnostic Support in Hospitalized Veterans With Acute Kidney Injury
Acute kidney injury (AKI) affects up to 20% of hospitalized Veterans and is strongly associated with morbidity and death. AKI is a diverse condition and timely and accurate diagnosis of the type of AKI is critical to begin…
- Trial name
- PRECISE-AKI (NCT07217808)
- Testing
- PRECISE-AKI Clinical Decision Support Tool
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- VA Office of Research and Development
Diabetes Mellitius
Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 As Biomarkers of AKI in Children With DKA
Type 1 diabetes mellitus (T1DM) is a common, chronic, metabolic disorder that has significant consequences for physical and emotional development .
- Trial name
- AKI (NCT06032325)
- Testing
- Neutrophil Gelatinase and Kidney Injury Molecule-1
- Volunteers
- 48 people
- Sponsor
- Assiut University
Acute Kidney Injury, Acute Interstitial Nephritis
Biorepository to Support Research in Kidney Diseases
To support advances in the understanding of pathophysiology and therapies of kidney diseases by creating a BioBank of kidney tissue, DNA, plasma, and urine from patients with kidney diseases.
- Conditions
- Acute Kidney Injury, Acute Interstitial Nephritis, Kidney Diseases
- Trial name
- NCT04343417
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Yale University
Critical Illness, COVID-19 Pneumonia
Acute Kidney Injury in Coronavirus Disease-19 (COVID-19) Patients Admitted to the Intensive Care Unit (ICU)
The aim of this study is to evaluate the rate and outcomes of COVID-19 associated acute kidney injury (AKI) and use of kidney replacement therapy (KRT) in critically ill COVID-19 patients in ICUs in several large hospitals in…
- Conditions
- Critical Illness, COVID-19 Pneumonia, Acute Kidney Injury
- Trial name
- COVID-AKI-B (NCT04997915)
- Testing
- Observational study exploring the epidemiology and outcomes of AKI in critical COVID-19 patients admitted to the ICU
- Where
- 9 sites in Belgium
- Volunteers
- 1,286 people
- Sponsor
- University Hospital, Ghent
Acute Kidney Injury, Acute Renal Failure
Review of Trend in Incidence and Characteristics of Hospital-acquired Acute Kidney Injury in Hospital Selayang
This retrospective cohort study aims to investigate the incidence, risk factors and outcomes of Hospital-acquired Acute Kidney Injury in Hospital Selayang, a tertiary hospital at Malaysia, over 15 years.
- Conditions
- Acute Kidney Injury, Acute Renal Failure, Kidney Failure, Acute, Hospital Acquired Condition
- Trial name
- HA-AKI-HS (NCT03353389)
- Testing
- No AKI, CA-AKI, HA-AKI
- Where
- Malaysia
- Volunteers
- 170,000 people
- Sponsor
- Selayang Hospital
Acute Kidney Injuries, Acute Kidney Disease
Trimethoprim-Sulfamethoxazole (TMP/SMX) Prophylaxis After Acute Kidney Injury to Prevent Post-discharge Infections
Official Title Trimethoprim-Sulfamethoxazole (TMP/SMX) Prophylaxis After Acute Kidney Injury to Prevent Post-discharge Infections: A Randomized, Double-Blind, Placebo-Controlled Trial Brief Summary Acute kidney injury (AKI) is…
- Conditions
- Acute Kidney Injuries, Acute Kidney Disease, Acute Kidney Injury (AKI)
- Trial name
- NCT07224997
- Testing
- Drug: Trimethoprim-Sulfamethoxazole (TMP/SMX) 160/800 mg tablets every 48 hours
- Volunteers
- 120 people
- Sponsor
- Hospital Civil de Guadalajara
Acute Kidney Injury, COVID
Pediatric Acute Kidney Injury in COVID-19
This study is an observational registry of children with or suspected to have SARS CoV2 (COVID-19) admitted to pediatric intensive care units (PICU).
- Trial name
- SPARC-1 (NCT04466306)
- Where
- 47 sites in United States, Canada and 5 more
- Volunteers
- 400 people
- Sponsor
- Children's Healthcare of Atlanta
Heart Failure Acute, Renal Dysfunction
Contrast-Induced Acute Kidney Injury Prevention in Acute Heart Failure
The K-PROSE study is a randomized clinical investigation evaluating strategies to prevent contrast-induced acute kidney injury (CI-AKI) in patients hospitalized with acute heart failure and moderate renal dysfunction (eGFR 30-75…
- Trial name
- K-PROSE (NCT07550790)
- Testing
- Furosemide, 0.9 % Normal Saline
- Where
- South Korea
- Volunteers
- 190 people
- Sponsor
- Jin Joo Park
Acute Kidney Injury
ProNephro NGAL Test for Early Detection of Acute Kidney Injury in Adult ICU Patients (ALPACA)
The purpose of this study is to evaluate the performance of the ProNephro AKI™ (NGAL) test for identifying critically ill adults at risk of developing moderate to severe acute kidney injury (KDIGO Stage 2/3) within 48 to 72 hours…
- Trial name
- ALPACA (NCT07751913)
- Testing
- ProNephro AKI™ (NGAL)
- Where
- 4 sites in United States
- Volunteers
- 800 people
- Sponsor
- BioPorto Diagnostics
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