Clinical trials: Renal Insufficiency, Acute
End-Stage Renal Disease, Renal Dialysis
Effects of Horticultural Therapy on Acute Stress and Salivary Cortisol Levels in Hemodialysis Patients
The purpose of this study is to evaluate the acute psychological and physiological effects of a single-session structured horticultural therapy program on patients undergoing routine hemodialysis.
- Conditions
- End-Stage Renal Disease, Renal Dialysis, Acute Stress
- Trial name
- NCT07845214
- Testing
- Horticultural Therapy
- Volunteers
- 80 people
- Sponsor
- Ataturk University
Critical Illness
Use of Vasopressin in Patients at High Risk of Acute Kidney Injury Admitted to the ICU
Renal dysfunction is a frequent complication in patients admitted to intensive care units (ICUs), associated with high morbidity and mortality.
- Trial name
- NOVA-AKI (NCT06547892)
- Testing
- Vasopressin, 0,9% saline solution
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital do Coracao
Hepatorenal Syndrome, Liver Regeneration, AKI - Acute Kidney Injury
Renal Histopathology and Transcriptomic Analysis in Hepatorenal Syndrome During Liver Transplantation
Hepatorenal Syndrome (HRS) is a serious complication that can occur in patients with liver cirrhosis, characterised by kidney dysfunction, or acute kidney failure (AKI).
- Conditions
- Hepatorenal Syndrome, Liver Regeneration, AKI - Acute Kidney Injury, Liver Transplant
- Trial name
- NCT07300709
- Testing
- renal biopsy
- Where
- Hong Kong
- Volunteers
- 42 people
- Sponsor
- The University of Hong Kong
Rhabdomyolysis
Pediatric Rhabdomyolysis in the Pediatric Intensive Care Unit: A Retrospective Cohort Study
This retrospective observational cohort study aims to evaluate the clinical characteristics, causes, intensive care management, and outcomes of pediatric patients with rhabdomyolysis admitted to the Pediatric Intensive Care Unit…
- Trial name
- NCT07851987
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Hannover Medical School
Heart Failure, Congestive
Efficacy and Safety of Relaxin for the Treatment of Acute Heart Failure
Different doses of relaxin will be compared to placebo to determine efficacy and safety for the treatment of patients hospitalized with acute heart failure
- Trial name
- RELAX-AHF (NCT00520806)
- Testing
- Relaxin
- Where
- 3 sites in United States, Israel
- Volunteers
- 1,161 people
- Sponsor
- Corthera, Inc.(formerly BAS Medical, Inc.), a member of the Novartis group of companies
Sepsis-Associated Organ Dysfunction, RTT
CRRT Timing in Sepsis-associated AKI in ICU
Sepsis continues to be a major global cause of both mortality and morbidity. Furthermore, the development of acute kidney injury (AKI) in sepsis increases the risk of unfavorable outcomes.
- Trial name
- CRTSAKI (NCT03175328)
- Testing
- continuous renal replacement therapies
- Where
- 2 sites in China
- Volunteers
- 460 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Acute Kidney Injury
Biomarkers of Kidney Function in Transplant Medicine
Biomarkers of kidney function in transplant medicine is an international, multicentre, observational, non-interventional study. The project is aimed at monitoring biomarkers of acute kidney dysfunction in deceased organ donors…
- Trial name
- NCT05538234
- Testing
- Laboratory values - baseline, Medical information 12 hours before organ harvesting, Laboratory values - 12 hours after reperfusion
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- University Hospital Ostrava
Continuous Renal Replacement Therapy
Continuous Versus Conventional Volume Management During CRRT (Continuous Renal Replacement Therapy)
Use of on-line blood volume monitoring during continuous renal replacement therapy can improve volume management in acute kidney injury patients requiring renal replacement
- Trial name
- NCT01405092
- Testing
- use of continuous renal replacement machine for renal replacement, use of blood volume monitoring device in conjunction with machine used for continuous renal replacement to assess and determine volume removal
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Dallas VA Medical Center
Acute Kidney Injury, Chronic Renal Disease
Prediction of Chronic Renal Disease After Acute Kidney Injury in the Intensive Care Unit
The study aims to develop and validate a prediction score of chronic renal disease occurrence within 3 years after ICU discharge in patients who suffered an acute kidney failure during ICU stay and recovered normal renal function…
- Trial name
- PREDICT (NCT03282409)
- Where
- France
- Volunteers
- 425 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Lung Injury, Sepsis
Extracardiac Complications After Cardiac Surgery
Hypothesis of the study is that patients undergoing major cardiac surgery can develop extracardiac complications correlated to cardiopulmonary by pass.
- Conditions
- Acute Lung Injury, Sepsis, Infections, Acute Kidney Injury
- Trial name
- NCT01187004
- Where
- Italy
- Volunteers
- 164 people
- Sponsor
- University of Turin, Italy
Acute Renal Failure
Fenoldopam and Ketanserin for Acute Kidney Failure Prevention After Cardiac Surgery
The purpose of the study is to compare the effect of fenoldopam and ketanserin on kidney function preservation in patients at high risk for renal failure after cardiac surgery.
- Trial name
- NCT00557219
- Testing
- fenoldopam (Corlopam), ketanserin (Sufrexal)
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Gdansk
Thrombotic Microangiopathy, Acute Kidney Injury
French National Cohort MATRIX "Renal and Systemic Thrombotic Microangiopathy"
Thrombotic microangiopathies (TMAs) are a diverse, rare but serious group of diseases. Progress has been made regarding the epidemiology of TMA (Bayer CJASN 2019).
- Conditions
- Thrombotic Microangiopathy, Acute Kidney Injury, Hemolytic Uremic Syndrome, Nephrology
- Trial name
- MATRIX (NCT05991245)
- Testing
- Collecting datas
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Tours
Contrast Induced Nephropathy
Erythropoietin in Radiocontrast Induced Nephropathy (ERIN) Trial
Full Title: A Randomized Controlled Trial of Procrit for the Prevention of Acute Renal Failure in Patients Receiving Intravenous Contrast Primary Objective: To evaluate the efficacy of a one-time dose of intravenous…
- Trial name
- ERIN (NCT00476619)
- Testing
- erythropoeitin
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Brigham and Women's Hospital
Acute Kidney Injury
Preventing Acute Kidney Injury
Acute kidney injury increases the risk for chronic kidney disease, length of stay, readmissions and mortality. Currently the only way to diagnose acute kidney injury is with a serum creatinine or drop in urine output.
- Trial name
- NCT04376619
- Testing
- remote ischemic preconditioning, KDIGO guidelines
- Volunteers
- healthy volunteers welcome
- Sponsor
- Atlantic Health System
Renal Injury, Acute
Acute Kidney Injury : Long-term Renal and Cardiovascular Prognosis and Biomarker-based Risk Assessment
Patients who develop severe acute kidney injury (AKI) in intensive care remain at increased long-term risk of mortality, major cardiovascular events, and chronic renal complications, including prolonged dependence on renal…
- Trial name
- AKIRA (NCT07596407)
- Where
- France
- Volunteers
- 412 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Kidney Injury
Is There Any Prognostic Value of Serum Uromodulin in Sepsis Induced AKI.
To determine whether baseline (day 0; day of diagnosis),day 7 and on discharge serum uromodulin levels help predict clinical outcomes in adult patients with sepsis induced AKI.
- Trial name
- NCT07295392
- Volunteers
- 30 people
- Sponsor
- Assiut University
Acute Kidney Injury, Probiotics
Effect of Probiotics and Prebiotics in Renal Function in Septic Acute Kidney Injury Patients
Septic acute kidney injury is a condition associated with highly related to inflammatory molecules. Prebiotics and probiotics have shown to improve inflammatory cascade in animal model; In this study, the investigators propose…
- Conditions
- Acute Kidney Injury, Probiotics, Sepsis
- Trial name
- NCT03877081
- Testing
- Probiotics
- Where
- Mexico
- Volunteers
- 90 people
- Sponsor
- Hospital Civil de Guadalajara
Renal Failure
Multicenter, Prospective, Rand, PK Study of LCP-Tacro™ Compared to Prograf® Capsules in De Novo Adult Kidney Transplant
The purpose of this study is to evaluate the pharmacokinetics of LCP-Tacro tablets administered once-daily compared to Prograf capsules administered twice-daily after kidney transplantation.
- Trial name
- NCT01666951
- Testing
- LCP-Tacro tablets, Prograf
- Where
- 13 sites in United States
- Volunteers
- 36 people
- Sponsor
- Veloxis Pharmaceuticals
Acute Renal Failure
Efficacy of Erythropoietin to Prevent Acute Kidney Injury in Chronic Kidney Disease Patients Undergoing Cardiac Surgery
The purpose of this study is to demonstrate the efficacy of erythropoietin for prevention acute kidney injury in CKD patients undergoing cardiac surgery.
- Trial name
- NCT01066351
- Testing
- beta erythropoietin
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Thammasat University
Renal Transplant
A Study of the Correlation Between Donor UDP-Glc and Transplanted Kidney Function
Kidney transplantation is the preferred treatment for end-stage renal disease (ESRD), however, organ shortage is the primary bottleneck restricting the progression of organ transplantation.1 Organs from Expanded Criteria Donors…
- Trial name
- NCT06707272
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Qianghua Leng
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