Clinical trials: Renal Insufficiency, Acute
End Stage Renal Disease
Brain Swelling During Dialysis
The proposed controlled, randomized study aims to compare pre-dilution hemodiafiltration (HDF) and low flux hemodialysis (HD) regarding acute changes in the brain. The study consist of two examination days placed one week apart.
- Trial name
- BRASE (NCT01396863)
- Testing
- HDF during the first examination, HD during the first examination
- Where
- 2 sites in Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Pathogenesis, Acute Kidney Injury
Perioperative Mechanism of Acute Kidney Injury in Cardiovascular Surgery
Continuous observation of acute renal injury after cardiac surgery, at the same time retention of blood samples, to test indicators，and to select the research route from the clinical actual test results .
- Conditions
- Pathogenesis, Acute Kidney Injury, Cardiac Surgery
- Trial name
- NCT03557047
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Contrast-induced Nephropathy
Contrast-Induced Nephropathy After Revision of the Prophylaxis Threshold
After administration of intravascular iodinated contrast media Contrast-Induced Nephropathy (CIN), also known as Contrast-Induced Acute Kidney Injury (CIAKI), may occur.
- Trial name
- CINART (NCT03227835)
- Testing
- intravascular iodinated contrast material administration
- Where
- Netherlands
- Volunteers
- 1,372 people
- Sponsor
- Maastricht University Medical Center
Acute Kidney Injury
Renal Biomarkers to Predict Recovery Following Venoarterial Extracorporeal Membrane Oxygenation
The investigators objective is to assess the utility of renal biomarkers in predicting renal recovery following institution of Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO).
- Trial name
- NCT02978378
- Testing
- biomarker levels
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Milton S. Hershey Medical Center
Leukemia, Renal Toxicity
Kidney Dysfunction in Children and Young Adults Who Have Received Methotrexate for Acute Lymphoblastic Leukemia
RATIONALE: Gathering information about how often kidney dysfunction occurs in children and young adults receiving methotrexate for acute lymphoblastic leukemia may help doctors learn more about the disease and plan the best…
- Trial name
- NCT00993135
- Testing
- methotrexate, medical chart review, assessment of therapy complications
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Vanderbilt University Medical Center
Critical Illness, Hyperglycemia
Prognostic Value of Stress Hyperglycemia Ratio in Critically Ill Patients
Critically ill patients admitted to intensive care units (ICUs) frequently develop elevated blood sugar levels (hyperglycemia) as a result of acute illness-related stress, even if they do not have diabetes.
- Conditions
- Critical Illness, Hyperglycemia, Acute Kidney Injury, Multiple Organ Failure
- Trial name
- NCT07853911
- Volunteers
- 230 people
- Sponsor
- Assiut University
Acute Kidney Injury, Dexmedetomidine
The Effect of Dexmedetomidine on Kidney Function in EVAR
This study will investigate the effect of dexmedetomidine on the incidence of postoperative acute kidney injury in patients undergoing EVAR under general anesthesia
- Conditions
- Acute Kidney Injury, Dexmedetomidine, Endovascular Aortic Repair
- Trial name
- DEVAR (NCT04766047)
- Testing
- Dexmedetomidine
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- University of Thessaly
Acute Calculous Anuria, Ureteral Calculi
Intravesical Aminophylline for Urgent Ureteral Stenting in Acute Calculous Anuria
Acute calculous anuria is a urological emergency caused by ureteral stone obstruction in a solitary functioning kidney or bilateral ureteral obstruction.
- Conditions
- Acute Calculous Anuria, Ureteral Calculi, Obstructive Uropathy, Acute Kidney Injury
- Trial name
- NCT07617948
- Testing
- Intravesical Aminophylline
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Beni-Suef University
Critical Illness, COVID-19 Pneumonia
Acute Kidney Injury in Coronavirus Disease-19 (COVID-19) Patients Admitted to the Intensive Care Unit (ICU)
The aim of this study is to evaluate the rate and outcomes of COVID-19 associated acute kidney injury (AKI) and use of kidney replacement therapy (KRT) in critically ill COVID-19 patients in ICUs in several large hospitals in…
- Conditions
- Critical Illness, COVID-19 Pneumonia, Acute Kidney Injury
- Trial name
- COVID-AKI-B (NCT04997915)
- Testing
- Observational study exploring the epidemiology and outcomes of AKI in critical COVID-19 patients admitted to the ICU
- Where
- 9 sites in Belgium
- Volunteers
- 1,286 people
- Sponsor
- University Hospital, Ghent
the Arterial Stiffness
Arterial Stiffness in Patients With Sepsis
To investigate whether arterial stiffness, as defined by measuring Pulse Wave Velocity, could be identified as an independent risk factor for development of acute kidney injury in sepsis.
- Trial name
- NCT06527443
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Chemotherapy Side Effects, Machine Learning
Prospective Validation of Machine Learning Model to Predict Platinum Induced Nephrotoxicity in Cancer Patients
This study aims to investigate the utility of predictive models for chemotherapy-induced nephrotoxicity in the Taiwanese cancer population.
- Conditions
- Chemotherapy Side Effects, Machine Learning, Acute Kidney Injury, Acute Kidney Disease
- Trial name
- NCT07114276
- Testing
- Machine learning models predictions of acute kidney injury and acute kidney disease
- Where
- Taiwan
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
COVID-19, Organ Dysfunction Syndrome Sepsis
Mechanisms for Organ Dysfunction in Covid-19
The study aims to investigate organ dysfunction and biomarkers in patients with suspected or verified COVID-19 during intensive care at Uppsala University Hospital.
- Conditions
- COVID-19, Organ Dysfunction Syndrome Sepsis, Organ Dysfunction Syndrome, Multiple, Septic Shock
- Trial name
- UMODCOVID19 (NCT04316884)
- Where
- Sweden
- Volunteers
- 380 people
- Sponsor
- Uppsala University
Acute Kidney Injury, Cardiac Surgery
Amino Acid Infusion in Cardiac Surgery
The goal of this study is to see if an infusion of amino acids given to adult male and female patients during cardiac surgery can help prevent acute kidney injury that commonly occurs when patients undergo cardiac surgery needing…
- Trial name
- NCT07030933
- Testing
- Travesol 10%
- Volunteers
- 130 people
- Sponsor
- Milton S. Hershey Medical Center
Acute Myocardial Infarction, Diabetes Mellitus
Association of Long-term Conditions With Survival Following Heart Attack in England and Wales
This study aims to determine the extent to which pre-existing long-term conditions are associated with survival following a heart attack (acute myocardial infarction) using observational data from the UK's national heart attack…
- Conditions
- Acute Myocardial Infarction, Diabetes Mellitus, Peripheral Vascular Disease, Chronic Heart Failure
- Trial name
- NCT03037255
- Testing
- long term conditions
- Volunteers
- 693,633 people
- Sponsor
- Marlous Hall
Acute Kidney Injury, Renal Insufficiency, Acute
VExUS-guided Fluid Management in Patients With Acute Kidney Injury in the Intensive Care Unit
A quasi experimental study that aims to verify whether the incorporation of VExUS in patients with AKI in the Intensive Care Unit (ICU) may prompt tailored interventions to increases the number of days free from Renal Replacement…
- Conditions
- Acute Kidney Injury, Renal Insufficiency, Acute, Kidney; Disease, Acute, Critical Illness
- Trial name
- AKIVEX (NCT05240833)
- Testing
- VExUS Score
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Heart Transplantation
Remote Ischemic Preconditioning and Acute Kidney Injury in HTX
Postoperative Acute Kidney Injury (AKI) is a common complication after heart transplantation (HTX) affecting outcome of patients.
- Trial name
- RIPCAT (NCT05364333)
- Testing
- Remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
NIRS, Cardiac Surgery Associated - Acute Kidney Injury
A Comparison of Renal vs Limb NIRS for Predicting Cardiac Surgery Associated Acute Kidney Injury
Acute kidney injury (AKI) is a complication of cardiac surgery that can affect outcome. Near Infrared Spectroscopy (NIRS) is a technology that uses light to determine how well oxygenated tissues are.
- Conditions
- NIRS, Cardiac Surgery Associated - Acute Kidney Injury, Cardiac Surgery Requiring Cardiopulmonary Bypass, AKI - Acute Kidney Injury
- Trial name
- NCT06705855
- Testing
- NIRS sensor placement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Acute Kidney Injury
Preop Digifab in CABG to Reduce Ouabain Levels and Prevent AKI
Acute kidney injury (AKI) occurs in up to 30% of patients undergoing coronary artery bypass graft (CABG) surgery, and often requires patients to go on dialysis.
- Trial name
- NCT03810417
- Testing
- Digoxin Antibodies Fab Fragments, Baseline EO > 360 pM, EO < 360 pM
- Where
- 2 sites in United States
- Volunteers
- 267 people
- Sponsor
- University of Maryland, Baltimore
Acute Kidney Injury
Care Bundle and Acute Kidney Injury Progression
The goal of this clinical interventional study is to learn about the effect of implementing a care bundle in the progression of acute kidney injury (AKI) in critical patients.
- Trial name
- NCT05597332
- Testing
- Care bundle for AKI
- Volunteers
- 400 people
- Sponsor
- University of Campinas, Brazil
Acute Renal Failure, Critical Illness
Characterization of the Efficacy of Furosemide Depending on Albumin Function
During this prospective, uncontrolled and non-interventional observational study, the influence of albumin function on the efficacy of furosemide will be investigated.
- Trial name
- NCT04972617
- Testing
- albumin function analysis (ABIC)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Rostock
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