Clinical trials: Renal Insufficiency, Chronic
Renal Insufficiency, Chronic
Effects of Fasting Mimetic Diet on Nephropatic Patients
Fasting mimetic diet (FMD) showed positive effects on cardiovascular risks. Purpose of the trial is to evaluate FMD effects on patients affected by chronic kidney disease (CKD), through the stimulation of kidney stem cells and…
- Trial name
- NCT04490252
- Testing
- Fasting mimetic diet
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- University of Roma La Sapienza
Chronic Kidney Diseases
RENACTIF: Reduction of the Thrombotic Phenotype in Renal Insufficiency With N-AcetylCysteine
Chronic Kidney Disease (CKD) is a known risk factor of cardiovascular morbidity and mortality. In CKD, decline of renal function results in the accumulation of uremic toxins in blood and tissue, such as Indoxyl Sulfate (IS).
- Trial name
- RENACTIF (NCT03636932)
- Testing
- N-acetylcysteine (NAC), Blood sample
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Coronary Calcification
Effects of Fhytomenadione on Coronary Artery Calcification of Hemodialysis Patients
Until 2013 the reported incidence of chronic kidney disease varied widely between countries, reporting the highest prevalence Taiwan, the region of Jalisco in Mexico and United States, with 458, 421 and 363 individuals per…
- Trial name
- NCT04247087
- Testing
- phytomenadione
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Mexicano del Seguro Social
End Stage Renal Disease (ESRD), Peritoneal Dialysis Complication
The Effect of Exercise on Low Back Pain in Peritoneal Dialysis Patients
The goal of this randomized controlled trial is to find out if exercise can help reduce low back pain and improve quality of life in people receiving peritoneal dialysis (PD).
- Trial name
- NCT07000006
- Testing
- Home-based Core Stability Exercise
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Pardis Specialized Wellness Institute
Kidney Diseases, End Stage Renal Disease
Ixazomib for Desensitization
The purpose of this research study is to find out how well ixazomib (the study drug) works to desensitize highly sensitized kidney transplant recipients.
- Trial name
- IXADES (NCT03213158)
- Testing
- Ixazomib Oral Capsule
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Wisconsin, Madison
Iron Deficiency Anemia, Iron Deficiency Anaemia
An Extension Trial to Assess the Safety of Re-dosing of Iron Isomaltoside/Ferric Derisomaltose (Monofer®/Monoferric®)
Evaluate safety and efficacy of intravenous (IV) iron isomaltoside/ferric derisomaltose re-dosing, in subjects who were previously treated with iron isomaltoside/ferric derisomaltose.
- Trial name
- FERWON-EXT (NCT02962648)
- Testing
- Iron isomaltoside/ferric derisomaltose
- Where
- 22 sites in United States
- Volunteers
- 103 people
- Sponsor
- Pharmacosmos A/S
Acute Kidney Injury, Contrast Media Toxicity
Curcuminoids and Contrast-induced Acute Kidney Injury
The objective of this study was to evaluate the role of curcuminoids in the prevention of CI-AKI in CKD patients.The result of the study was prophylactic administration with curcuminoids in addition to standard treatment reduce…
- Conditions
- Acute Kidney Injury, Contrast Media Toxicity, Curcuminoid, Chronic Kidney Diseases
- Trial name
- NCT04890704
- Testing
- Curcuminoid
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
End Stage Renal Disease
Fluid Overload in Peritoneal Dialysis
The objective of this study is to determine the effectiveness of treating peritoneal dialysis (PD) patients with fluid overload by a structured nurse-lead intervention protocol.
- Trial name
- NCT02557347
- Testing
- Aggressive fluid management
- Where
- Hong Kong
- Volunteers
- 102 people
- Sponsor
- Chinese University of Hong Kong
Heart Transplantation
Exchange of Azathioprine by Mycophenolatmofetile and Cyclosporine A Dose Reduction After Heart Transplantation
The purpose of this study is to improve or save renal function by optimizing the immunosuppressive regimen by reducing the Cyclosporine A dose and the exchange of Azathioprine by Mycophenolatmofetile, which is an effective…
- Trial name
- NCT00359814
- Testing
- Mycophenolatmofetile, Cyclosporin A
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Hannover Medical School
Chronic Renal Failure
A Multicenter, Randomized, Open-labeled, Cross-over, Active-controlled, Phase IV Clinical Trial to Evaluate the Preference of Formulation and the Efficacy and Safety of Renamezin and Kremezin in Pre-dialysis Patients With Chronic Renal Failure
A Multicenter, Randomized, Open-labeled, Cross-over, Active-controlled, Phase IV Clinical Trial to Evaluate the Preference of Formulation and the Efficacy and Safety of Renamezin and Kremezin in Pre-dialysis Patients With Chronic…
- Trial name
- NCT02681952
- Testing
- Renamezin capsule, Kremezin granule
- Where
- South Korea
- Volunteers
- 153 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Hyperkalemia
Pharmacodynamic & Safety of Patiromer in Children & Adolescents (2-<18 Yrs) With Chronic Kidney Disease and Hyperkalemia
The purpose of this study is to evaluate the change in serum potassium levels from start of treatment to Day 14, when patiromer is administered at different doses, once daily, in children 2 - < 18 years of age with chronic kidney…
- Trial name
- EMERALD (NCT03087058)
- Testing
- Patiromer
- Where
- 30 sites in United States, Bulgaria and 5 more
- Volunteers
- 23 people
- Sponsor
- Vifor Pharma, Inc.
Kidney Transplantation, End Stage Kidney Disease (ESRD)
Novel Desensitization Kidney Transplantation
This proposal's objective is to determine whether belatacept, in conjunction with a proteasome inhibitor can be used to safely increase the likelihood of finding an acceptable donor for highly HLA sensitized kidney transplant…
- Trial name
- NCT05345717
- Testing
- Belatacept Injection
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Chicago
Complication of Dialysis, Chronic Kidney Disease
Efficacy of Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation in Hemodialysis Patients
The purpose of this study is to examine the effect of 6 months of daily beta-hydroxy beta-methylbutyrate (HMB) supplementation on the physical function and the health of bones, arteries and heart in hemodialysis patients.
- Conditions
- Complication of Dialysis, Chronic Kidney Disease, Muscle Loss, End Stage Renal Disease
- Trial name
- NCT01837238
- Testing
- HMB
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Illinois at Urbana-Champaign
Chronic Kidney Diseases
Beetroot Extract Supplementation Associated With an Exercise Protocol for Chronic Kidney Disease Patients
Chronic kidney disease (CKD) patients often present systemic inflammation and oxidative stress, resulting in metabolic disorders and high rates of disease-associated cardiovascular death.
- Trial name
- NCT06286748
- Testing
- Beetroot juice
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Universidade Federal Fluminense
End Stage Renal Disease, ESRD
Safety and Efficacy Assessments of NeoKidney® in ESRD Patients Treated With Short Daily Hemodialysis
The goal of this clinical investigation is to asses the safety and efficacy a new sorbent-based hemodialysis device, NeoKidney® in ESRD patients treated with short daily hemodialysis.
- Trial name
- FIH Caen (NCT06024135)
- Testing
- NeoKidney
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Nextkidney S.A.
End Stage Renal Disease, Continuous Ambulatory Peritoneal Dialysis
Open-label, Randomized Trial to Determine the Effect of Icodextrin Versus Dextrose (Dianeal 2.5%) in HOMA IR
Phase IV post-marketing study to evaluate the effect of Extraneal on the HOMA index in non-diabetic CAPD patients over the long-dwell exchange.
- Trial name
- ECOS (NCT01093547)
- Testing
- Blood samples, Measure of peritoneal ultrafiltrates
- Where
- Colombia
- Sponsor
- Vantive Health LLC
Lean Body Mass, Chronic Kidney Diseases
Novel Equations for Estimating Lean Body Mass in Patients With Chronic Kidney Disease
Simplified methods to estimate lean body mass (LBM), an important nutritional measure representing muscle mass and somatic protein, are lacking in non-dialyzed patients with chronic kidney disease (CKD).
- Trial name
- NCT04074278
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University First Hospital
End Stage Renal Disease, Nutrition
Endocannabinoids in End Stage Renal Disease
To investigate the relationship between dietary intake, body habitus, and endocannabinoid levels in end stage renal disease patients as compared to matched controls.
- Trial name
- NCT01477515
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Chronic Kidney Disease
Empowering Patients On Choices for Renal Replacement Therapy (Aim 3) (EPOCH-RRT)
Empowering Patients On Choices for Renal Replacement Therapy (EPOCH-RRT) study seeks to identify factors that matter the most to patients with kidney disease and study how they are impacted by different types of dialysis.
- Trial name
- EPOCH-RRT (NCT02488317)
- Testing
- Decision Aid
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Arbor Research Collaborative for Health
Renal Insufficiency, Chronic
Neurovascular Transduction During Exercise in Chronic Kidney Disease
The purpose of this study is to find out why patients with chronic kidney disease (CKD) have poor exercise capacity and to explore what causes an increase in blood pressure during exercise (i.e.
- Trial name
- NeurovEx (NCT02947750)
- Testing
- 6R-BH4, Folic acid, Exercise training
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Emory University
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