Clinical trials: Renal Insufficiency, Chronic
Kidney Diseases, Kidney Transplant
TreaT-Assay: the New Frontier for the Diagnosis of Acute Rejection in Kidney Transplantation
Kidney transplantation is the standard therapy for end-stage renal disease. Acute rejection (AR) or chronic rejection along with reactive donor immunity, which counteracts organ acceptance, are among the greatest medical…
- Conditions
- Kidney Diseases, Kidney Transplant, Kidney Disease, End-Stage
- Trial name
- NCT06801262
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
THROMBOSED AV GRAFTS
Pilot Study of IVUS Imaging During Endovascular Interventions of Failing Hemodialysis Access Grafts
This pilot study will provide data to aid in the planning of a follow-up multi-center randomized, controlled trial (RCT). As such, the sample size for this pilot is not driven by formal statistical hypothesis testing.
- Trial name
- NCT01929369
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Volcano Corporation
Chronic Kidney Diseases
Cerebrovascular Dysregulation in Chronic Kidney Disease
The purpose of this study is to test whether or not regular exercise training may improve brain blood flow regulation in patients with chronic kidney disease (CKD).
- Trial name
- NCT05571605
- Testing
- Exercise, Stretching
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of North Texas, Denton, TX
Chronic Kidney Disease Requiring Chronic Dialysis
Integrating BIA and eGFR for Nutritional Status in Hemodialysis Patients
This study looks at how measurements of body composition from Bioelectrical Impedance Analysis (BIA) and estimates of kidney function (eGFR) can be applied together to better assess the health of people on hemodialysis.
- Trial name
- NCT06873880
- Where
- Estonia
- Volunteers
- 30 people
- Sponsor
- University of Tartu
Chronic Kidney Disease (Stage 3-4)
Effect Of Education On Adherence, Self Care And Well-Being Of Patients With Chronic Kidney Disease
ABSTRACT Aim: The aim of the study was evaluate the effect of education provided to patients diagnosed with chronic kidney disease on adherence to illness, self-care, and well-being. Design: A randomised controlled trial.
- Trial name
- NCT07309861
- Testing
- Educational with chronic kidney disease
- Where
- Turkey (Türkiye)
- Volunteers
- 119 people
- Sponsor
- Trakya University
Chronic Kidney Disease, End Stage Kidney Disease
Reduction of Mortality Prior to and During the First 90 Days of Dialysis Through a Renal Rehabilitation Program
The mortality rate of treated patients with end stage renal disease(ESRD)is 22 deaths patient-years at risk in 2006. Incident patients with ESRD are most vulnerable within the first 90 days of dialysis, with an annualized…
- Conditions
- Chronic Kidney Disease, End Stage Kidney Disease, Cardiovascular Disease
- Trial name
- NCT00792454
- Testing
- exercise training
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- MaineHealth
Chronic Kidney Disease
An Observational Study to Learn More How Chronic Kidney Disease Gradually Changes Over Time in Adults Using Electronic Healthcare Records (CKD Natural History Study)
This is an observational study in which the health data of people with chronic kidney disease are studied using electronic healthcare records.
- Trial name
- CKD-NH (NCT05914259)
- Testing
- No Intervention
- Where
- Germany
- Volunteers
- 969,394 people
- Sponsor
- Bayer
Hyperphosphatemia, End Stage Renal Disease
Ferric Citrate for the Treatment of Hyperphosphatemia in Patients With Chronic Kidney Disease Undergoing Hemodialysis
To evaluate the efficacy and safety of ferric citrate tablet in the control of serum phosphorus levels in patients with chronic kidney disease undergoing hemodialysis.
- Conditions
- Hyperphosphatemia, End Stage Renal Disease, ESRD
- Trial name
- NCT04456803
- Testing
- Ferric citrate tablet, Sevelamer carbonate tablet
- Where
- 20 sites in China
- Volunteers
- 239 people
- Sponsor
- Sinomune Pharmaceutical Co., Ltd
Paediatric Kidney or Liver Transplantation, Chronic Kidney Disease
Prevention of Human Papillomavirus (HPV) Infection in Paediatric Kidney and Liver Transplant Recipients and in Paediatric Patients With Advanced Chronic Kidney Disease
Due to their immunosuppressive therapy, solid-organ transplant (SOT) recipients bear a 10 to 100 times higher risk of human papillomavirus (HPV)-associated malignancies than healthy individuals.
- Trial name
- NCT03100682
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- University Hospital Heidelberg
Kidney Failure, Chronic
Use of Tinzaparin for Anticoagulation in Hemodialysis
The HEMO-TIN trial is designed to look at both the safety (bleeding risk) and effectiveness (clotting risk) of tinzaparin compared with unfractionated heparin for anticoagulation in hemodialysis patients.
- Trial name
- HEMO-TIN (NCT01930396)
- Testing
- Tinzaparin, Unfractionated Heparin
- Where
- Canada
- Volunteers
- 191 people
- Sponsor
- Christine Ribic
Inflammation, Chronic Kidney Disease
Pentraxin-3 in Chronic Renal Failure
The aim of the study is to measure Pentraxin-3 levels in patients on hemodialysis, peritoneal dialysis and those in the pre-dialysis period; and to compare these groups with the control group; so as to investigate the eligibility…
- Trial name
- NCT01397773
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Haseki Training and Research Hospital
ANCA Associated Vasculitis
Multicenter Cohort Study of AAV in Hunan of China
This study aimed to explore the incidence of Anti-neutrophil cytoplasmic antibody (ANCA）-associated vasculitis (AAV) progression and its association with adverse consequences.
- Trial name
- NCT05315141
- Testing
- No Intervention
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xiangya Hospital of Central South University
Chronic Kidney Disease, Diabetes Mellitus
Facilitating Improvements in Kidney Health Using a Smartphone App Counseling Program in Patients With Diabetes
This pilot study tests the feasibility of dietary app-supported tele-counseling in the treatment of patients with stage 1-3a chronic kidney disease (CKD) and diabetes.
- Conditions
- Chronic Kidney Disease, Diabetes Mellitus, Albuminuria
- Trial name
- FitKidney (NCT03015480)
- Testing
- Remote counseling
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Geisinger Clinic
Myocardial Infarction, Cerebral Infarction
Acute Myocardial Infarction and Acute Cerebral Infarction (AMIAC) Registry and Follow-up
A registry of consecutive patients who were admitted and diagnosed with acute myocardial infarction or acute cerebral infarction were conducted at the Guangdong General Hospital or the First Affiliated Hospital of Guangzhou…
- Conditions
- Myocardial Infarction, Cerebral Infarction, Chronic Kidney Diseases, Mortality
- Trial name
- AMIAC (NCT03166696)
- Where
- 3 sites in China
- Volunteers
- 30,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Chronic Kidney Disease
Evaluation of New Markers to Assess Kidney Function
Glomerular filtration rate (GFR) is widely accepted as the best index of kidney function in health and disease, and accurate values are required for optimal clinical decision making and in large-scale epidemiologic studies and…
- Trial name
- NCT00938561
- Testing
- Inulin
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Calcific Uremic Arteriolopathy (CUA), Calciphylaxis
European Calciphylaxis Registry Network
Observational, registry, prospective, non-interventional collection of CUA patient data. Patient treatment is carried out within clinical routine, at the discretion of the physicians and according to existing treatment…
- Trial name
- EuCalNet (NCT02635373)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- RWTH Aachen University
Severe Renal Impairment
Prophylactic Desmopressin Before Native Kidney Biopsy in Severe Renal Impairment
This study evaluated whether giving desmopressin before a native kidney biopsy reduces bleeding complications in adults with severe renal impairment (eGFR <30 mL/min/1.73 m²).
- Trial name
- NCT07840313
- Testing
- Desmopressin Acetate, NO DESMOPRESSIN
- Where
- Pakistan
- Volunteers
- 250 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Renal Failure, Chronic, Renal Transplantation
Immunoregulatory Effects of Immunoglobulin Induction Therapy in Renal Transplant Recipients
The aim of this randomized prospective study in renal transplant recipients is to investigate immunological short and long-term effects of an IVIG induction therapy.
- Trial name
- NCT00176059
- Testing
- intravenous immunoglobulins (IVIG), kidney transplantation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Giessen
Dialysis; Complications, Heparin-induced Thrombocytopenia
Multicenter Study on Dialysis Modalities for End-stage Chronic Renal Failure Patients With Heparin-induced Thrombocytopenia
This research is based on the hypothesis that the Hydrolink®-NV dialysis membrane could allow the realization of quality dialysis with a significant reduction in the doses of Orgaran®, or even a total cessation of the…
- Conditions
- Dialysis; Complications, Heparin-induced Thrombocytopenia, Chronic Renal Failure
- Trial name
- MODIATIH (NCT05586854)
- Testing
- Hydrolink NV membrane
- Where
- France
- Volunteers
- 20 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Chronic Kidney Disease
A Study of PRT-201 Administered Immediately After Radiocephalic Arteriovenous Fistula(AVF) Creation in Patients With Chronic Kidney Disease (CKD) (PATENCY-1)
This research study is designed to assess the safety and effectiveness of an experimental drug called PRT-201 in patients both receiving or expecting to receive dialysis who have chronic kidney disease and who are undergoing…
- Trial name
- NCT02110901
- Testing
- PRT-201
- Where
- 35 sites in United States
- Volunteers
- 349 people
- Sponsor
- Proteon Therapeutics
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