Clinical trials: Renal Insufficiency,Chronic
Chronic Kidney Disease(CKD), Type 2 DM
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)
IRIS-CKD is an implementation study to improve guideline-recommended screening of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D) in the United States.
- Conditions
- Chronic Kidney Disease(CKD), Type 2 DM, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- IRIS-CKD (NCT06906627)
- Testing
- (IRIS-CKD Screening Program): Home Kit, (IRIS-CKD Screening Program): Standard Lab Order
- Where
- 7 sites in United States
- Volunteers
- 500 people
- Sponsor
- Duke University
End Stage Renal Disease, Arteriovenous Fistula
Role of Monocytes Adhesion and Vascular Lesions in Vascular Access Success or Failure in Uremic Patients
This study is designed to identify novel predictors of vascular access success or failure in chronic kidney disease patients. Despite efforts to improve placement of arteriovenous fistula (AVF) the primary failure rates are…
- Trial name
- ROMAVAS (NCT03231410)
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Chronic Renal Failure
Hyperbaric Oxygen Therapy for Renal Regeneration in Diabetic Nephropathy
Diabetes kidney disease is a leading cause for end stage renal disease in the western world. To date no treatment that can reverse renal damage exists.
- Trial name
- NCT03376282
- Testing
- Hyperbaric Oxygen oxygen therapy (HBOT)
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- Assaf-Harofeh Medical Center
Chronic Renal Failure, Hemodialysis
The Effect of CoQ10 Administration on Hemodialysis Patients
The purpose of this study is to examine whether CoQ10 administration is effective as an antioxidant in hemodialysis patients.
- Trial name
- NCT00307996
- Testing
- Coenzyme Q10 (drug)
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- University of Shizuoka
Kidney Failure, Chronic, Kidney Failure, Acute
Sodium Chloride and Contrast Nephropathy
This phase II, open, non-inferiority, randomized and controlled clinical trial is aimed to ascertain the incidence of contrast nephropathy in outpatients undergoing CT scan with contrast.
- Conditions
- Kidney Failure, Chronic, Kidney Failure, Acute, Heart Failure, Diabetes
- Trial name
- PNIC-Na (NCT03476460)
- Testing
- Oral sodium chloride, Intravenous sodium chloride
- Where
- Spain
- Volunteers
- 271 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Chronic Kidney Diseases, Heart Failure
REducing Sympathetic Activity Through Ultrasound-based Renal deneRvation in Excessive Cardiovascular Risk populaTions.
The is a non-randomized pilot trial, open-label evaluation of the physiologic response of native kidney denervation using the Paradise denervation system in CKD, End Stage Renal Disease (ESRD), and Heart failure (HF)
- Conditions
- Chronic Kidney Diseases, Heart Failure, End Stage Renal Disease
- Trial name
- RESURRECT (NCT05703620)
- Testing
- Renal Denervation
- Where
- Australia
- Volunteers
- 75 people
- Sponsor
- Royal Perth Hospital
End Stage Renal Disease
Evaluation of the GORE® ACUSEAL Vascular Graft for Hemodialysis Access
This study is a prospective, non-randomized, multi-center evaluation of the performance of the GORE® ACUSEAL Vascular Graft. The study will enroll patients with End-Stage Renal Disease (ESRD), who are either currently receiving…
- Trial name
- ACUSEAL (NCT01173718)
- Testing
- GORE® ACUSEAL Vascular Graft
- Volunteers
- 138 people
- Sponsor
- W.L.Gore & Associates
Chronic Kidney Disease, Hypertension
Urinary Uromodulin, Dietary Sodium Intake and Ambulatory Blood Pressure in Patients With Chronic Kidney Disease
In chronic kidney disease (CKD), hypertension is characterized by the phenomenon of sodium-sensitivity, i.e., the disproportionate increase in blood pressure (BP) due to an increase in dietary sodium consumption to maintain…
- Trial name
- NCT06363097
- Where
- Greece
- Volunteers
- 130 people
- Sponsor
- Aristotle University Of Thessaloniki
Chronic Renal Failure
Post-Marketing Surveillance on Long-Term Drug Use of Kiklin (Bixalomer)® Capsules in Patients With Hyperphosphatemia Receiving Peritoneal Dialysis
To evaluate the safety and efficacy of long-term use of Kiklin® Capsules in actual clinical settings.
- Trial name
- NCT01903213
- Testing
- bixalomer
- Where
- 8 sites in Japan
- Volunteers
- 123 people
- Sponsor
- Astellas Pharma Inc
Chronic Kidney Disease
Salivary Phosphorus and Level of Kidney Function
The specific purpose of this study is to describe the relationship between salivary phosphorus and kidney function, specifically as it relates to serum phosphorus, FGF23, PTH, vitamin D status and urinary excretion of phosphorus.
- Trial name
- NCT01311973
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Denver Nephrologists, P.C.
Heart Diseases, Heart Valve Diseases
Acute Kidney Injury After Cardiac Surgery
The study aims to identify the Following: - 1. incidence and mortality of cardiac Surgery associated -AKI based on the new consensus diagnostic systems of KDIGO (Kidney Disease Improving Global Outcomes). 2.
- Conditions
- Heart Diseases, Heart Valve Diseases, Heart Shock, Cardiac Disease
- Trial name
- NCT05079724
- Testing
- Cardiac Surgery
- Volunteers
- 200 people
- Sponsor
- Assiut University
Kidney Failure, Chronic
Short Term Effects of FX Dialysers on QOL and Inflammation
Background: The new hollow fibre FX-class of dialysers (Fresenius Medical Care, Bad Homburg, Germany) features a number of technological improvements that may benefit the patient.
- Trial name
- NCT00291603
- Testing
- FX-class of dialyser
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Sir Charles Gairdner Hospital
Chronic Kidney Disease
A Study of AST-120 for Evaluating Prevention of Progression In Chronic Kidney Disease Including Assessment of Quality of Life (EPPIC-2)
1) To evaluate the effectiveness of AST-120 (spherical carbon adsorbent) added to standard-of-care therapy in moderate to severe Chronic Kidney Disease (CKD), on time to first occurrence of any event of the triple composite…
- Trial name
- NCT00501046
- Testing
- AST-120
- Where
- 106 sites in United States, Argentina and 10 more
- Volunteers
- 1,015 people
- Sponsor
- Tanabe Pharma Corporation
End Stage Renal Disease
The Effects of Nutrition Supplementation and Resistance Exercise During Hemodialysis
To test the hypothesis that an exercise session combined with adequate nutritional supplementation improves skeletal muscle protein accretion during a hemodialysis session.
- Trial name
- NCT00179179
- Testing
- nutritional supplementation, exercise
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Vanderbilt University
End Stage Renal Disease
Impact of Clinical Pharmacy Services on Medication Cost and Hospitalization Rates in Hemodialysis Patients
The purpose of this study is to evaluate the effects of pharmaceutical care interventions in the ambulatory hemodialysis patients over a one-year period.
- Trial name
- NCT05952388
- Testing
- Behavioral Patient care
- Sponsor
- University of New Mexico
Chronic Kidney Disease, Patients Requiring Heparin Free Dialysis Treatments
HepZero:Heparin Free Dialysis With Evodial
The study hypothesis is that with Evodial in patients requiring heparin free dialysis, the heparin free treatment can be performed easily (without saline flushes or blood predilution) and is at least not inferior and maybe…
- Trial name
- NCT01318486
- Testing
- Heparin free dialysis technique, Evodial
- Where
- 10 sites in Belgium, Canada and 5 more
- Volunteers
- 265 people
- Sponsor
- Vantive Health LLC
Chronic Kidney Disease, Periodontitis
Chronic Kidney Disease Associated Diet
The goal of this observational study is to investigate the relationship between chronic kidney disease (CKD) and periodontitis, and to evaluate the potential mediating role of dietary inflammatory potential, measured by the…
- Conditions
- Chronic Kidney Disease, Periodontitis, Diet, Food and Nutrition
- Trial name
- NCT07427069
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Kidney Failure, Acute, Kidney Failure, Chronic
An Investigation of N-acetylcysteine and Fenoldopam as Renal Protection Agents for Cardiac Surgery
Patients with abnormal kidney function are at increased risk for complications following heart surgery, including worsening kidney function possibly requiring dialysis, a prolonged stay in the critical care unit and hospital, and…
- Conditions
- Kidney Failure, Acute, Kidney Failure, Chronic, Cardiac Surgical Procedures
- Trial name
- NCT00122018
- Testing
- N-acetylcysteine, fenoldopam
- Volunteers
- 80 people
- Sponsor
- Linda F. Barr, M.D.
Chronic Kidney Disease (CKD), Hyperkalemia
Chronic Kidney Disease, Hyperkalemia and Echocardiographic Changes
Patients with CKD ( eGFR \< \<60 mL/min/1,73 m2) presenting to emergency department with isolated hyperkalemia will be study population. Pre and post treatment ECG and echocardiographic findings will be recorded.
- Conditions
- Chronic Kidney Disease (CKD), Hyperkalemia, Hemodialysis
- Trial name
- NCT06635590
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Saglik Bilimleri Universitesi
Knee Osteoarthristis, Diabetes (DM)
The NTU JO-SMART Study
This study recruits patients with coexisting obesity and knee osteoarthritis (KOA) to implement the NTU-JO Smart Program, an innovative intervention integrating AI-assisted community-based exercise with continuous glucose…
- Conditions
- Knee Osteoarthristis, Diabetes (DM), Obesity & Overweight, Chronic Kidney Disease
- Trial name
- NCT07317310
- Testing
- NTU-JO Smart Program
- Where
- 2 sites in Taiwan
- Volunteers
- 312 people
- Sponsor
- National Taiwan University Hospital
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