Clinical trials: Renal Insufficiency,Chronic
Chronic Kidney Diseases, Acute Kidney Injury
The Stockholm CREAtinine Measurements Project
The Stockholm CREAtinine Measurements (SCREAM) project is a healthcare utilization cohort including, at present, all adult residents in Stockholm between 2006 and 2021.
- Conditions
- Chronic Kidney Diseases, Acute Kidney Injury, Diabetes Mellitus, Cardiovascular Diseases
- Trial name
- SCREAM (NCT06239129)
- Testing
- Initiation of specific medications, Undertaking of specific procedures, Abnormalities in specific laboratory tests
- Volunteers
- 3,200,000 people
- Sponsor
- Karolinska Institutet
Chronic Kidney Disease
Effects of a Non-Calcium Based Phosphate Binder on FGF23 Levels in Chronic Kidney Disease
Fibroblast Growth Factor 23 (FGF23) is a molecule that has been implicated in the homeostasis of phosphorus. Elevated FGF23 levels are well-documented in patients with Chronic Kidney Disease (CKD) and are inversely correlated…
- Trial name
- NCT01308242
- Testing
- Sevelamer Carbonate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Hemodialysis, Ischemia Preconditioning
Assessment of the Impact of Repeated Ischemic Preconditioning Episodes on Hemodynamic and Metabolic Parameters in Patients at Various Stages of Chronic Kidney Disease
The aim of our study is to evaluate the impact of repeated episodes of ischemic quenching on changes in blood pressure, heart rate and laboratory parameters of inflammation in patients with kidney diseases.
- Conditions
- Hemodialysis, Ischemia Preconditioning, Chronic Kidney Disease, Blood Pressure Disorders
- Trial name
- NCT07746102
- Testing
- Preconditioning with control ischemic episodes
- Where
- 2 sites in Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Restless Legs Syndrome, End-Stage Renal Disease
A Sleep Laboratory Study to Investigate the Safety and Efficacy of the Rotigotine Skin Patch in Subjects With Restless Legs Syndrome and End-Stage Renal Disease Requiring Hemodialysis
This is a sleep laboratory study to evaluate the efficacy and safety of Rotigotine in subjects with Restless Legs Syndrome and End-Stage Renal Disease requiring hemodialysis.
- Trial name
- NCT01537042
- Testing
- Rotigotine
- Where
- 15 sites in United States, Austria and 4 more
- Volunteers
- 30 people
- Sponsor
- UCB BIOSCIENCES GmbH
Hypertension Resistant to Conventional Therapy, Kidney Failure, Chronic
Chemical Renal Ethanol Sympatholysis Under CT Guidance Use for the Control of Therapy-Resistant Hypertension
In this study the investigators are going to assess the feasibility of this innovate technique of renal sympathetic denervation by translumbar access under ct-guidance.
- Trial name
- SCRATCH (NCT02653222)
- Testing
- Renal sympathicolysis, Ambulatory Blood Pressure Monitoring, Magnetic Resonance Angiography
- Where
- 2 sites in France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Grenoble
Renal Insufficiency, Chronic, Organ Graft
Therapeutic Education of Chronic Renal or Renal Transplant Patient in the Management of EPO Injections
In chronic kidney disease, ESAs (Erythropoiesis-stimulating agents) are used to treat anemia. This anemia is due to decreased renal production of erythropoietin (EPO), a hormone that stimulates the production of red blood cells…
- Trial name
- SELFEPO (NCT03481686)
- Testing
- Patients with injections of ESA
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Rennes University Hospital
Chronic Kidney Diseases
Effects of Prebiotic Supplementation and Exercise on Inflammatory Markers, Vascular Function and Cognition in CKD
The study is primarily designed to examine the effect of 16 weeks of prebiotic supplementation (resistant starch)and moderate intensity aerobic training on markers of inflammation in stage 3-4 patients with chronic kidney disease.
- Trial name
- NCT03689569
- Testing
- Resistant starch, Exercise, Starch
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Springfield College
Chronic Kidney Disease, Insulin Resistance
Study of Vitamin D3 Supplementation in Patients With Chronic Kidney Disease
The purpose of this study is to evaluate the impact of vitamin D3 supplementation on the insulin resistance in non-diabetic patients with chronic kidney disease (CKD) stages 3-4, vitamin D deficiency/insufficiency and elevated…
- Conditions
- Chronic Kidney Disease, Insulin Resistance, Vitamin D Deficiency
- Trial name
- VitaD-CKD1 (NCT00893451)
- Testing
- cholecalciferol (TillVal-D)
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Sahlgrenska University Hospital
Chronic Renal Insufficiency
Effect of Cytokines on Growth of Children With Chronic Kidney Failure
Children with chronic kidney failure often do not grow well. This study examines the possible causes of growth failure in these children and the response to recombinant human growth hormone.
- Trial name
- NCT00194883
- Testing
- Recombinant Human Growth Hormone
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weill Medical College of Cornell University
Chronic Kidney Disease
Symptom Assessment And Management For Adults With CKD In Vietnam
Adults with chronic kidney disease (CKD) have many symptoms that lower their quality of life and put a huge burden on the healthcare system.
- Trial name
- SAM-CKD (NCT07186361)
- Testing
- Symptom Assessment and Management Program (SAM-CKD) which is delivered via Smart Kidney mobile app
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Griffith University
Chronic Kidney Diseases
Impact of Chronic Kidney Disease on Postural Stability in Children
Background: Chronic kidney disease is associated with comorbid conditions that result in physical impairments. Objectives: Investigate the impact of chronic kidney disease (CKD) on postural stability in children compared with age…
- Trial name
- NCT04411927
- Testing
- assessment of postural stability
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cairo University
CKD (Chronic Kidney Disease) Stage 5T, Diabetes Mellitus
Observational Study to Evaluate the Safety and Efficacy of Polyclonal Antibodies in Simultaneous Pancreas Kidney Transplant Recipients
A single-centre, prospective, observational study to evaluate the safety and efficacy of Polyclonal Antibodies in simultaneous Pancreas Kidney Transplant recipients.
- Conditions
- CKD (Chronic Kidney Disease) Stage 5T, Diabetes Mellitus, Simultaneous Pancreas Kidney Transplantation
- Trial name
- PAISPK (NCT03470961)
- Testing
- Anti-Tlymphocyte Globulins, Anti-Thymocyte Globulins
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Tianjin First Central Hospital
Kidney Failure
Evaluation of the Efficacy and Tolerance of Plasmapheresis by Double Cascade Filtration in a University Centre
A study is being carried out to evaluate the biological, technical and clinical/biological efficacy of this technique, the practice of which is standardized in the department, in order to evaluate our practices and to improve…
- Trial name
- DFPPSURV (NCT04261205)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Infection, Heart Failure
Prediction of Patient Deterioration Using Machine Learning
This is a retrospective observational study drawing on data from the Brigham and Women's Home Hospital database. Sociodemographic and clinic data from a training cohort were used to train a machine learning algorithm to predict…
- Conditions
- Infection, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT05045742
- Testing
- Traditional vital sign alarms versus the BioVitals Index vs the National Early Warning Score 2
- Where
- 2 sites in United States
- Volunteers
- 526 people
- Sponsor
- Brigham and Women's Hospital
Hemodialysis, End Stage Kidney Disease (ESKD)
Dialysis Less Frequently in the Elderly
Many people who have kidney failure require hemodialysis treatments to stay alive. Hemodialysis is a procedure that cleans the blood of the toxins and fluids that build up when kidneys don't work.
- Trial name
- DLITE (NCT07738731)
- Testing
- Twice weekly hemodialysis, Thrice weekly hemodialysis treatment
- Where
- 11 sites in Canada
- Volunteers
- 210 people
- Sponsor
- Queen's University
Chronic Kidney Disease
DD-study: Diet or Diuretics for Salt-sensitivity in Chronic Kidney Disease
In this clinical study the anti-hypertensive response to dietary salt restriction is compared with the anti-hypertensive response to the diuretics hydrochlorothiazide/amiloride in adult patients with chronic kidney disease.
- Trial name
- DD (NCT02875886)
- Testing
- Amiloride, Hydrochlorothiazide, Low-sodium diet
- Where
- Netherlands
- Volunteers
- 28 people
- Sponsor
- Erasmus Medical Center
Chronic Kidney Failure
Observational Study of Kibow Biotics in Dialysis Patients
A specifically formulated probiotic product comprised of defined and tested microbial strains may afford renoprotection in what has been generally called "Enteric DialysisTM".
- Trial name
- NCT01450670
- Testing
- Kibow Biotics
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kibow Pharma
Infection, Heart Failure
Remote Physician Care for Home Hospital Patients
This study examines the implications of providing remote physician care to home hospitalized patients compared to usual home hospital care with in-person/in-home physician visits.
- Conditions
- Infection, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT04080570
- Testing
- Remote Visit
- Where
- 2 sites in United States
- Volunteers
- 172 people
- Sponsor
- Brigham and Women's Hospital
Hemodialysis, Kidney Disease, Chronic
Intradialysis Exercise Functional Capacity, Body Composition and Survival in Hemodialysis Patients
Chronic kidney disease and renal replacement treatments (hemodialysis, peritoneal dialysis, kidney transplant) produce various alterations at the level of muscle, bones, fat content and the heart; can alter physical capabilities…
- Conditions
- Hemodialysis, Kidney Disease, Chronic, Physical Activity, Physical Deconditioning
- Trial name
- NCT06788054
- Testing
- intradialysis exercise
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Universidad de Guanajuato
Sarcopenia, Chronic Kidney Disease
The Effects of Frailty on Chronic Kidney Disease
Frailty is a syndrome characterized by decreased reserve and diminished resistance to stressors. The proposed research will evaluate the association of frailty with chronic kidney disease (CKD).
- Trial name
- NCT02775305
- Testing
- Frail
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- San Francisco Veterans Affairs Medical Center
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