Clinical trials: Renal Insufficiency,Chronic
Atrial Fibrillation, Elderly Patients
Glomerular Filtration Rate-Estimating Equations During Use of Direct Oral Anticoagulants in Elderly Patients
Atrial fibrillation in the elderly is a complex condition due to the high number of frequently associated comorbidities such kidney disease.
- Conditions
- Atrial Fibrillation, Elderly Patients, Chronic Kidney Disease
- Trial name
- REINACO (NCT02964546)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 116 people
- Sponsor
- University Hospital, Montpellier
Kidney Failure, Chronic
Effects of Aerobic Training in End Stage Renal Disease Patients
The investigators raised the hypothesis that exercise training would be associated with improvement in exercise tolerance and VO2 kinetics in hemodialysis patients.
- Trial name
- NCT01234688
- Testing
- Exercise training
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Federal University of Juiz de Fora
Kidney Failure, Chronic
Resistance Training and Diet in Patients With Chronic Renal Failure
This study will examine the effects of long-term adherence to a low protein diet (LPD) of 0.6 g/kg-1/d-1 with and without progressive resistance exercise training in patients with impaired renal function on body composition…
- Trial name
- NCT00018317
- Testing
- low protein diet, resistance training, combination of diet control and exercise
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Renal Insufficiency
Pirfenidone Capsule in Patients With Chronic Kidney Disease G2 and G3a Study on Safety and Pharmacokinetics
To evaluate the safety and pharmacokinetic characteristics of pirfenidone capsules in chronic kidney disease G2 and G3a patients, and to provide a basis for the phase II clinical trial program
- Trial name
- NCT04126538
- Testing
- pirfenidone capsule
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Beijing Continent Pharmaceutical Co, Ltd.
Chronic Kidney Disease, Pulmonary Embolism
Safety of Low Dose IV Contrast CT Scanning in Chronic Kidney Disease
The purpose of this study is to show that the use of low volume iso-osmolar non-ionic radio contrast medium (30 cc) in a thoracic CT Scanning procedure in a selected group of patients with chronic kidney disease (CKD) will avoid…
- Conditions
- Chronic Kidney Disease, Pulmonary Embolism, Renal Artery Stenosis, Pulmonary Cancer
- Trial name
- NCT02476526
- Testing
- Low Volume iso-osmolar non-ionic radio contrast medium, Acetylcysteine Inhalation, Sodium Bicarbonate Solution
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Greater Los Angeles Healthcare System
End-stage Renal Disease
Usefulness and Acceptability of a Connected Ergocycle for the Elderly in a Clinical Setting
Hospitalizations are harmful to patients. Without a proper intervention, it will lead to a permanent decline in physical function, especially among frail individuals.
- Trial name
- NCT05404633
- Testing
- Ergogycle prototype testing for acceptability
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Diabetic Nephropathies, Diabetic Glomerulosclerosis
Transformative Research in Diabetic Nephropathy
This is a prospective, observational, cohort study of patients with a clinical diagnosis of diabetes who are undergoing clinically indicated kidney biopsy.
- Trial name
- TRIDENT (NCT02986984)
- Testing
- There is no intervention
- Where
- 17 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Pennsylvania
Anemia, Kidney Failure
Erythropoietin Resistance in Anemia of Chronic Kidney Disease
Our goal of this pilot project is to identify inflammatory biomarkers that correlate with epo-resistance among CKD patients.
- Conditions
- Anemia, Kidney Failure, Erythropoietin
- Trial name
- NCT00526747
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Duke University
Kidney Transplant, ESRD (End Stage Renal Disease)
Improving Access to Renal Transplantation for Underserved Black Communities
The goal of this clinical trial is to learn whether the African American Transplant Access Program can be successfully replicated at another large kidney transplant program.
- Trial name
- AATAP (NCT06707038)
- Testing
- AATAP intervention
- Where
- United States
- Sponsor
- Northwestern University
Chronic Kidney Disease, IgA Nephropathy
Pilot Study of Velcade® in IgA Nephropathy
The primary objective of this study is to investigate the ability of Velcade® (bortezomib) to induce complete or partial remission in patients with severe IgA nephropathy.
- Trial name
- NCT01103778
- Testing
- Bortezomib (Velcade®)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- The Rogosin Institute
Nephrotic Syndrome
Part 1 - A Clinical Trial in Patients With Frequently Relapsing and Steroid-Dependent Nephrotic Syndrome
A Clinical Trial Investigating the Safety and Efficacy of ADX-629 in Subjects with Frequently Relapsing and Steroid-Dependent Nephrotic Syndrome
- Trial name
- NCT05599815
- Testing
- ADX-629
- Where
- 11 sites in United States
- Sponsor
- Aldeyra Therapeutics, Inc.
Arterial Hypertension
Fetuin A as a Predictor of Deterioration of Renal Function in Hypertonic Patients
Commonly used parameters (creatinine, estimated glomerular filtration rate, and urine albumin/creatinine ratio) for prediction of decline of renal function are sensitive for advanced kidney impairment.
- Trial name
- NCT05963126
- Testing
- No intervention.
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital Ostrava
Chronic Kidney Insufficiency
Diuretic/Cool Dialysate Trial
The proposed pilot study challenges the current widespread paradigm of discontinuing loop diuretics when initiating chronic HD and/or maintaining the dialysate at a constant temperature of 37 °C for all patients.
- Trial name
- DIDIT (NCT02593526)
- Testing
- Bumetanide, Cool Dialysate
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of New Mexico
Anemia of Chronic Kidney Disease
Comparison of Darbepoetin Alpha and Recombinant Human Erythropoietin for Treatment of Anemia in Children With Chronic Kidney Disease
The present study was designed to determine whether or not darbepoetin alfa is non-inferior to recombinant human erythropoietin in the treatment of anemia in children with chronic kidney disease stage 3-5 (on or not on dialysis).
- Trial name
- NCT04959578
- Testing
- Recombinant human erythropoietin, Darbepoetin Alfa
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Rufaida Mazahir
Peritoneal Dialysis (PD), End Stage Renal Disease (ESRD)
DKK3 as a Biomarker of Peritoneal Fibrosis in Peritoneal Dialysis Patients
Peritoneal dialysis (PD) uses the peritoneal membrane as a natural filter to remove waste products from the blood in patients with kidney failure.
- Conditions
- Peritoneal Dialysis (PD), End Stage Renal Disease (ESRD), Peritoneal Fibrosis, Ultrafiltration Failure
- Trial name
- PERIMARK (NCT07806708)
- Testing
- Modified Peritoneal Equilibration Test and DKK3 Biomarker Measurement
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Universität des Saarlandes
Chronic Kidney Disease
Immunologic Abnormalities, Chronic Inflammation and Oxidative Stress in Chronic Kidney Disease
The common causes of mortality are late stages of chronic kidney disease, cardiovascular disease and infections, are associated with abnormalities of the immune system, an underlying state of chronic inflammation and oxidative…
- Trial name
- NCT00793806
- Testing
- Diffuse Optical Spectroscopy
- Where
- 3 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Renal Insufficiency Chronic, Chronic Periodontitis
Effect on Teeth and Gum Cleaning in Patients With Gum and Kidney Disease
The main aim and objective of this study was to evaluate the effects of Non- surgical periodontal therapy on the subgingival microbiota and biochemical parameters in patients with chronic kidney disease and chronic periodontitis.
- Trial name
- ETGPGK (NCT02901743)
- Testing
- Scaling and Root planing
- Volunteers
- 40 people
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Chronic Kidney Diseases
Nurse-led Physician-supported Care for Patients With Chronic Kidney Disease and Multimorbidity
Chronic kidney disease (CKD) is a prevalent chronic disease and is often intertwined with the management of cardiovascular disease and the optimization of metabolic risk factors.
- Trial name
- INTEGREATCKD (NCT06372743)
- Testing
- INTEGREAT-CKD Intervention
- Where
- Singapore
- Volunteers
- 220 people
- Sponsor
- Alexandra Hospital
End Stage Renal Disease
Cinacalcet Study to Reach Kidney Disease Outcomes Quality Initiative (K/DOQI) Levels
The purpose of this study is to observe the effects of a treatment strategy that incorporates cinacalcet HCl into the management of secondary hyperparathyroidism (HPT) to K/DOQI recommended targets in subjects with end stage…
- Trial name
- NCT00113958
- Testing
- Cinacalcet
- Sponsor
- Amgen
End Stage Renal Disease, Continuous Ambulatory Peritoneal Dialysis
Open-label, Randomized Trial to Determine the Effect of Icodextrin Versus Dextrose (Dianeal 2.5%) in HOMA IR
Phase IV post-marketing study to evaluate the effect of Extraneal on the HOMA index in non-diabetic CAPD patients over the long-dwell exchange.
- Trial name
- ECOS (NCT01093547)
- Testing
- Blood samples, Measure of peritoneal ultrafiltrates
- Where
- Colombia
- Sponsor
- Vantive Health LLC
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