Clinical trials: Renal Insufficiency,Chronic
Chronic Kidney Disease, Dialysis
A Study of MCI-196 in Chronic Kidney Disease Stage V Subjects on Dialysis With Hyperphosphatemia
This is a PIII multi-center, open-label, flexible dose, long-term safety study, that in conjunction with the E07(NCT00416520), E08(NCT00542386) and E09(NCT00451295) studies will allow exposure to MCI-196 for up to 52 weeks
- Conditions
- Chronic Kidney Disease, Dialysis, Hyperphosphatemia
- Trial name
- NCT00542815
- Testing
- MCI-196, Another Phosphate binder (Sevelamer)
- Where
- 115 sites in Austria, Czechia and 13 more
- Volunteers
- 632 people
- Sponsor
- Tanabe Pharma Corporation
Chronic Kidney Disease (Stage 3-4)
Impact of Mindfulness on Pain In SA
Background: Patients with end-stage renal disease (ESRD) undergoing hemodialysis often experience chronic pain, maladaptive pain cognitions, and diminished quality of life, yet evidence on mindfulness-based interventions (MBIs)…
- Trial name
- MPSA (NCT07837206)
- Testing
- Mindfulness-Based Intervention
- Where
- Saudi Arabia
- Volunteers
- 38 people
- Sponsor
- Jordan University of Science and Technology
Essential Hypertension, Cardiovascular Disease
Prognostic Value of the Circadian Pattern of Ambulatory Blood Pressure for Multiple Risk Assessment
The HYGIA study was designed to investigate prospectively 1. the prognostic value of ambulatory blood pressure (BP) monitoring among subjects primarily evaluated at primary care settings 2.
- Conditions
- Essential Hypertension, Cardiovascular Disease, Stroke, Chronic Kidney Disease
- Trial name
- HYGIA (NCT00741585)
- Testing
- Any antihypertensive medication alone or in combination, Ambulatory blood pressure monitoring
- Where
- 20 sites in Spain
- Volunteers
- 21,983 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Chronic Kidney Disease
Loop Diuretics in Chronic Kidney Disease
The purpose of this study is to verify the efficacy of diuretic therapy on blood pressure control and left ventricular mass in patients affected by chronic kidney disease
- Trial name
- NCT00478543
- Testing
- Furosemide
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Campania Luigi Vanvitelli
End Stage Renal Disease, Hemodialysis Complication
The Effect of Home-Based Tele-Exercise on Dialysis Patients
The objective of the trial is to assess key areas of uncertainty regarding the use of synchronous home-based tele-exercise in future practice and research, including issues relating to feasibility, safety and potential for…
- Trial name
- NCT06313892
- Testing
- Home-based Exercise
- Where
- Iran
- Volunteers
- 26 people
- Sponsor
- Pardis Specialized Wellness Institute
Chronic Kidney Disease
Assessing Manual Components of Brazilian Children and Adolescents on Hemodialysis
The purpose of this study was to assess the handgrip strength; fine motor skills; and hand sensitivity of Brazilian children and adolescents with Chronic Kidney Diseases (CKD).
- Trial name
- NCT03065361
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Chronic Kidney Disease (CKD) Stage 5, Peritoneal Dialysis Access
PD Catheter Survival: Modified Percutaneous vs Moncrief-Popovich
Peritoneal dialysis (PD) catheter placement technique may affect catheter survival, functionality and infection risk. The Moncrief-Popovich (subcutaneous burying or embedding) technique was developed to reduce exit-site/tunnel…
- Trial name
- NCT07465445
- Testing
- Embedded Peritoneal catheter placement, Modified Percutaneous PD catheter placement
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Civil de Guadalajara
ESRD
Antibiotic Lock Solutions in the Prevention of Catheter Related Bacteremia
To study the efficacy of an antibacterial/anticoagulant solution instilled into the hemodialysis (HD) catheters after each treatment ("antibiotic lock solution - ALS") to prevent catheter related bacteremia (CRB) and to salvage…
- Trial name
- NCT00294502
- Testing
- Gentamycin/citrate, Minocycline/EDTA
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Chronic Renal Disease
The Lighthouse Tenofovir Cohort Study
Lighthouse, in cooperation with the University Heidelberg Public Health Institute and the University Köln (Cologne) would like to set up a cohort to study baseline characteristics and long-term clinical outcomes of patients using…
- Trial name
- LighTen (NCT02381275)
- Testing
- Tenofovir Disoproxil Fumarate
- Where
- Malawi
- Volunteers
- 1,500 people
- Sponsor
- Lighthouse Trust
Anemia, Renal Insufficiency, Chronic
Maintenance Treatment of Renal Anemia in Dialysis Subjects
The purpose of this study is to evaluate the efficacy and safety of molidustat in comparison to darbepoetin alfa in dialysis subjects with renal anemia who are treated with Erythropoiesis-Stimulating Agents (ESAs).
- Trial name
- MIYABI HD-M (NCT03543657)
- Testing
- Molidustat (BAY85-3934), Darbepoetin alfa
- Where
- 53 sites in Japan
- Volunteers
- 229 people
- Sponsor
- Bayer
End-stage Renal Disease, Thrombocytopathy
Cohort Study Comparing Short Daily Hemodialysis (HD) With Conventional HD
This study is examining the effects of short daily hemodialysis on platelet function, fluid volume control, arterial stiffness and patient quality of life, as compared to conventional hemodialysis.
- Conditions
- End-stage Renal Disease, Thrombocytopathy, Cardiovascular Diseases
- Trial name
- NCT00182156
- Where
- Canada
- Sponsor
- McMaster University
Chronic Renal Failure, Anemia
Safety & Efficacy of Pegolsihematide for Treatment of Anemia in Participants on Dialysis
The purpose of this study is to evaluate the safety and efficacy of multiple intravenous doses of pegol-Sihematide in participants with chronic kidney disease (CKD) who are on dialysis.
- Conditions
- Chronic Renal Failure, Anemia, Dialysis
- Trial name
- NCT02586402
- Testing
- pegol-Sihematide, Epoetin Alfa
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Renal Insufficiency, Chronic, Food Insecurity
Penn Produce Prescription and Chronic Kidney Disease Study
The goal of this pilot clinical trial is to examine the feasibility, acceptability, and likely effect of a produce prescription intervention on patient-centered outcomes, health behaviors and health outcomes, among food insecure…
- Trial name
- NCT06561412
- Testing
- Produce Prescription
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pennsylvania
Renal Insufficiency, Chronic, Kidney Failure, Chronic
Almond Milk With Vitamin D: Impact on Vitamin D Status
The overall goal is to enhance vitamin D status in a safe and effective manner. A 3-week randomized comparator-controlled trial among a cohort of adults with CKD (stages 3-5) (n=24) will test the main objective: Evaluate the…
- Trial name
- NCT05165173
- Testing
- NanoD4CKD, MicroD4CKD
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Florida
Coronary Artery Disease, Cerebral Vascular Disease
Pilot Study: Cardiovascular Events in High Risk Orthopedic Surgical Patients
This is a non-randomized, non-interventional pilot observational study designed to follow high-risk patients through their surgical and hospital stay.
- Conditions
- Coronary Artery Disease, Cerebral Vascular Disease, Peripheral Artery Disease, Renal Insufficiency
- Trial name
- NCT01809730
- Where
- United States
- Sponsor
- NYU Langone Health
Infection, Heart Failure
Home Hospital for Suddenly Ill Adults
The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be…
- Conditions
- Infection, Heart Failure, COPD, Asthma
- Trial name
- NCT03524222
- Testing
- Home Hospitalization
- Where
- 2 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Brigham and Women's Hospital
Heart Failure, Chronic Obstructive Pulmonary Disease (COPD)
Epidemiological Cluster Evaluation in Patients Admitted to Internal Medicine, With at Least One of the Following Diagnoses: Heart Failure, COPD, Renal Failure. The FADOI IN-CluDiMI Study
Improved medical care has led to an increase in both the age and clinical complexity of patients admitted to Internal Medicine wards, characterized by multiple chronic diseases.
- Conditions
- Heart Failure, Chronic Obstructive Pulmonary Disease (COPD), Chronic Kidney Disease (CKD)
- Trial name
- IN-CluDiMI (NCT07660757)
- Where
- Italy
- Volunteers
- 4,500 people
- Sponsor
- Fadoi Foundation, Italy
Chronic Kidney Disease
Telemonitoring to Improve Outcomes of Patients With Chronic Kidney Disease (CKD)
The purpose of this study is to determine if the adoption of a chronic care model in conjunction with tele monitoring and case management can reduce the risk of death, hospitalization, emergency room visits, or admission to a…
- Trial name
- NCT01446029
- Testing
- Video Telemonitoring Device with Clinical Care Modules
- Where
- United States
- Volunteers
- 601 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Chronic Kidney Disease(CKD), Chronic Kidney Disease Requiring Chronic Dialysis
Investigation of the Validity, Reliability, and Responsiveness of BETY-BQ in Chronic Kidney Disease, on Dialysis, and Kidney Transplantation
A review of the literature has shown that Chronic Kidney Disease (CKD) is strongly associated with an increasing degree of psychosocial impact, such as depression and anxiety and a decrease in quality of life.
- Conditions
- Chronic Kidney Disease(CKD), Chronic Kidney Disease Requiring Chronic Dialysis, Kidney Transplantation
- Trial name
- NCT06591702
- Testing
- Questionnaire study
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Hacettepe University
Chronic Kidney Disease
Study to Assess Relative Bioavailability and Safety of AZD5718 in Healthy Volunteers
This study will be a randomised, open-label, 3-period, 3-treatment, single-dose, crossover study in healthy subjects The study will be performed at a single study centre in the United Kingdom.
- Trial name
- NCT04734275
- Testing
- AZD5718
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
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