Clinical trials: Renal Stone Disease
Stone;Renal
Flexible Ureteroscopy Versus Mini-Percutaneous Nephrolithotomy for Treatment of Renal Stones
Management of nephrolithiasis is evolving rapidly, and various minimally-invasive urological procedures are currently available for treating patients with renal stones, including extracorporeal shockwave lithotripsy (ESWL)…
- Trial name
- NCT03932370
- Testing
- Flexible ureteroscopy, mini-Percutaneus nephrolithotomy
- Where
- Egypt
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Assiut University
Kidney Calculi
Suction Mini-PCNL Versus Standard PCNL for the Management of 2-4cm Kidney Stones
Percutaneous nephrolithotomy (PCNL) is recommended as the first-line treatment choice for kidney stones larger than 2cm in international guidelines .
- Trial name
- NCT05088213
- Testing
- suction mini percutaneous nephrolithotomy, standard percutaneous nephrolithotomy
- Where
- China
- Volunteers
- 960 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Calculi
Efficacy of Potassium Sodium Hydrogen Citrate Therapy on Renal Stone Recurrence and/or Residual Fragments After Shockwave Lithotripsy and Percutaneous Nephrolithotomy in Calcium Oxalate Urolithiasis
Extracorporeal shock wave lithotripsy (ESWL) and Percutaneous nephrolithotomy (PCNL) become the therapy of choice for renal stone.
- Trial name
- NCT01329042
- Testing
- Potassium-sodium citrate
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ouiheng International Healthcare Co., Ltd
Stone, Kidney, Child, Only
Shock Wave Lithotripsy Using Fluoroscopic Versus Ultrasonic Localization
Epidemiological studies have shown a progressive increase in the incidence of pediatric urolithiasis over the past few decades.
- Trial name
- NCT05413603
- Testing
- ultrasonic focus Shock wave lithotripsy, fluoroscopic focus Shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Egymedicalpedia
Nephrolithiasis
Tissue Sensor for Semirigid Thulium Fiber Laser Ureterolithotripsy
Tissue Sensor (TS) is a technology designed to automatically deactivate laser emission when contact between the laser fiber and tissue is detected.
- Trial name
- Tissue Sensor (NCT07835113)
- Testing
- Semirigid TFL ureterolithotripsy with Tissue Sensor activated., Semirigid TFL ureterolithotripsy with Tissue Sensor deactivated.
- Volunteers
- 121 people
- Sponsor
- Botkin Hospital
Kidney Stones
Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy
The Investigators objective is to compare the clinical efficacy of a single-day protocol with a short-course protocol for PCNL. The investigator hope is to reduce the use of possibly unnecessary prolonged antibiotic use, reduce…
- Trial name
- NCT02579161
- Testing
- cephalosporins, Fluoroquinolones, Clindamycin
- Where
- 2 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Large Renal Stone
A Comparative Study Between Anterior and Posterior Pyelotomy in Transperitoneal Laparoscopic Pyelolithotomy
Large renal pelvic stones are frequently managed with percutaneous nephrolithotomy (PCNL) but laparoscopic pyelolithotomy (LPL) can be an alternative procedure when performed by skilled surgeons to achieve excellent outcomes in…
- Trial name
- NCT06394219
- Testing
- traditional transperitoneal laparoscopic pyelolithotomy, modified transperitoneal laparoscopic pyelolithotomy
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Ureteral Stones, Ureteral Calculi
Antibiotic Prophylaxis Before Shock Wave Lithotripsy
This is a two arm, double blind RCT comparing the use of a single dose ciprofloxacin prior to SWL to saline alone. The multicenter trial will be conducted with a pragmatic emphasis including both high volume and low volume sites…
- Conditions
- Ureteral Stones, Ureteral Calculi, Nephrolithiasis
- Trial name
- APPEAL (NCT03692715)
- Testing
- Ciprofloxacin
- Where
- 10 sites in Brazil, Canada and 7 more
- Volunteers
- 1,732 people
- Sponsor
- Clinical Urology and Epidemiology Working Group
Nephrolithiasis, Renal Calculi
Comparison of Extracorporeal Shock Wave Lithotripsy Versus Retrograde Intrarenal Surgery in the Management of Renal Calculi
This study is being carried out in patients with kidney stones measuring between 1 and 2 centimeters. Kidney stones are common in Pakistan and can cause severe pain, infection, and repeated hospital visits.
- Trial name
- NCT07261995
- Testing
- Extracorporeal Shock Wave Lithotripsy (ESWL), Retrograde Intrarenal Surgery (RIRS)
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Ziauddin Hospital
Stone, Kidney, Lithiasis Renal
Standard-PCNL vs Mini-PCNL vs Super-mini PCNL for the Treatment of ≥2 cm Renal Stone
Background: Standard-PCNL was considered as the first choice for ≥2 cm renal stones. Miniaturized technique Mini-PCNL has also been implicated in the past two decades.
- Conditions
- Stone, Kidney, Lithiasis Renal, Surgery
- Trial name
- NCT03771365
- Testing
- Standard-PCNL, Mini-PCNL, SMP
- Volunteers
- 3,000 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Renal Calculi
Energy Ramping Versus Fixed Dose ESWL
This clinical trial compares two techniques of extracorporeal shock wave lithotripsy (ESWL) - energy ramping versus fixed dose - in adult patients with renal stones.
- Trial name
- NCT07334236
- Testing
- Extracorporeal shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- mohammed Abdelhafez
Ureteral Stent-Related Symptoms
Alfuzosin and Mirabegron for Double-J Stent Symptoms
This prospective randomized controlled trial investigates the effects of alfuzosin, mirabegron, and their combination on stent-related symptoms and outcomes in patients undergoing DJ stent placement after retrograde intrarenal…
- Trial name
- NCT07018934
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- University of Gaziantep
Lithiasis, Nephrolithiasis
Study of the Administration of a Food Supplement in Patients With Lithiasis Treated With Extracorporeal Shock Wave Lithotripsy.
The extracorporeal shock wave lithotripsy (ESWL) is the treatment of choice for most stones in any of their locations. It is about breaking the stone without surgically intervening on the patient and getting him to expel the…
- Trial name
- FAGOTRICIA (NCT05525130)
- Testing
- Food supplement
- Where
- 3 sites in Spain
- Volunteers
- 81 people
- Sponsor
- Arafarma Group, S.A.
Gallbladder Stones, Kidney Transplantation
Silent Gallbladder Stone in Kidney Transplantation Recipients: Should it be Treated?
Treatment and follow-up strategies for silent gallbladder (GB) stones in patients before KT (Kidney transplantation) remain unknown.
- Trial name
- NCT05945511
- Where
- South Korea
- Volunteers
- 2,295 people
- Sponsor
- Seoul National University Hospital
Nephrolithiasis
RIRS With Flex Suction Sheath vs. PCNL for 2-3 cm Renal Stones
This is a multicenter, randomized controlled trial comparing retrograde intrarenal surgery (RIRS) using a tip-flexible suction access sheath with standard percutaneous nephrolithotomy (PCNL) for the treatment of 2-3 cm unilateral…
- Trial name
- NCT07058402
- Testing
- Retrograde Intrarenal Surgery (RIRS) with Tip-Flexible Suction Access Sheath, Standard Percutaneous Nephrolithotomy (PCNL)
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Changhai Hospital
Nephrolithotomy Percutaneous, Kidney Calculi
Percutaneous Nephrolithotomy Without a Ureteral Catheter
Conventional Percutaneous nephrolithotomy (PCNL) surgery requires the patient to first undergo retrograde transurethral ureteroscopic insertion of the ureteral catheter in the lithotomy position, and then change the patient to…
- Trial name
- NCT05598671
- Testing
- PCNL without reverse insertion of a ureteral catheter
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital of University of South China
Kidney Stones, Urolithiasis
Evaluation of Stone Composition in Surgical Kidney Stone Patients in Vietnam
This is a prospective observational study conducted at Binh Dan Hospital, Ho Chi Minh City, Vietnam, from July to December 2023.
- Conditions
- Kidney Stones, Urolithiasis, Nephrolithiasis
- Trial name
- STONE-VN (NCT07038954)
- Testing
- Stone Composition Analysis
- Where
- Vietnam
- Volunteers
- 222 people
- Sponsor
- Binh Dan Hospital
Urinary Calculi
A Prospective Multicenter Randomized Controlled Trial of Flexible And Navigable Suction Ureteral Access Sheath Combined With Needle Perc for the Treatment of Partial Staghorn Renal Calculi
The goal of this clinical trial is to learn if flexible and navigable suction ureteral access sheath combined with needle perc works to treat partial staghorn renal calculi. It will also learn about the safety of drug ABC.
- Trial name
- NCT06914986
- Testing
- Performed flexible and navigable suction ureteral access sheath combined with needle perc, PCNL
- Volunteers
- 344 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Stone, Urinary, Stone, Kidney
Effect of Preop Stent Duration on SFR and Secondary Intervention in RIRS
This study aims to evaluate how placing a stent before surgery (preoperative stenting or passive dilation) affects the success rate of retrograde intrarenal surgery (RIRS), which is performed for kidney stones.
- Trial name
- NCT07052188
- Testing
- without any preoperative stenting, (DJ) stent placed with sedation and undergo RIRS within 2-4 weeks, Patients will have a DJ stent placed with sedation and undergo RIRS within 4-6 weeks.
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people
- Sponsor
- Bedreddin Kalyenci
Cystinuria, Nephrolithiasis, Calcium Oxalate
Use of an Herbal Preparation to Prevent and Dissolve Kidney Stones
We will investigate the safety and effectiveness of a mixture of 9 east Indian herbs known as Cystone regarding their ability to dissolve existing kidney stones and prevent formation of new ones.
- Trial name
- NCT00381849
- Testing
- Cystone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic