Clinical trials: Renal Stone Disease
Kidney Calculi, Crohn's Disease
Calcium Supplements Strategy for Kidney Stones Prevention in Crohn's Patients
Hospitalization for kidney stones in the Inflammatory Bowel Disease (IBD) population is common, particularly among Crohn's patients who had a small bowel resection.
- Trial name
- NCT01735461
- Testing
- Calcium Carbonate
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Hypouricemia, Renal, Urolithiasis
A Randomized Clinical Trail of The Effect of Postoperative Uric Acid Control on Stone Recurrence and Renal Function in Patients With Hyperuricemia of Urolithiasis.
The purpose of this study was to explore the effects of uric acid control on stone recurrence and renal function in patients with calculi of hyperuricemia through a prospective controlled study.
- Trial name
- NCT04398251
- Testing
- Febuxostat 40mg Tab, Non-drug control group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xuhui Central Hospital, Shanghai
Renal Stone
Stone Clearance in Patients With Upper Ureteric Stones Using Extracorporeal Shock Wave Lithotripsy Compared With Extracorporeal Shock Wave Lithotripsy Combined With Tamsulosin Therapy
Extracorporeal shock wave lithotripsy (ESWL) is the least invasive and effective treatment for upper ureteric stones with a stone clearance rate of 60-90%.
- Trial name
- NCT05725122
- Testing
- Extracorporeal shock wave lithotripsy, Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy.
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Services Hospital, Lahore
Nephrolithiasis
Mature Vinegar Prophylaxis Against Recurrent Calcium Oxalate Nephrolithiasis
Kidney stones are one of the most common disorders of the urinary tract and cause a great deal of morbidity and economic loss. Because of the high recurrence rate, researchers are interested in finding medicinal therapies to…
- Trial name
- NCT03092908
- Testing
- mature vinegar
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Stones
AR Projections for Eye-gaze Evaluation in Phantoms
This project aims to develop an augmented reality (AR) tool to enhance skill acquisition for endoscopic kidney stone surgery. Of the 100,000 patients who undergo an endoscopic kidney stone treatment annually in the United States…
- Trial name
- NCT07161024
- Testing
- Augmented reality
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Kidney Stone
Outcomes in Lower Pole Kidney Stone Management Using Mini-PCNL Compared With Retrograde Intra Renal Surgery
Due to the anatomic characteristics of the lower calyx, lower pole stones are difficult to be eliminated through the ureter, even if the stones had been fragmented.
- Trial name
- NCT05714423
- Testing
- Mini-PCNL, RIRS
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Services Hospital, Lahore
Hyperoxaluria, Nonalcoholic Fatty Liver Disease
A Study of BMN 255 in Participants With Non-Alcoholic Fatty Liver Disease And Hyperoxaluria
The purpose of this study is to test the safety of BMN 255 and to learn about the effect BMN 255 has on you and your hyperoxaluria associated with NAFLD, and compare these effects with a placebo.
- Conditions
- Hyperoxaluria, Nonalcoholic Fatty Liver Disease, Kidney Stone
- Trial name
- NCT06138327
- Testing
- BMN 255
- Where
- 7 sites in United States
- Sponsor
- BioMarin Pharmaceutical
Urothelial Carcinoma, Renal Cell Carcinoma
Prospective Trial for Examining Hematuria Using Computed Tomography
The primary objective is to evaluate whether one-phase nephrographic CT (experimental) is sufficient to detect urothelial cell carcinoma in patients with hematuria compared to the traditional four-phase CT (control).
- Conditions
- Urothelial Carcinoma, Renal Cell Carcinoma, Renal Cyst, Renal Stone
- Trial name
- PROTEHCT (NCT04077359)
- Testing
- CT
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Oslo University Hospital
Obesity, Kidney Stones
Influence of Hypocaloric Diet on Urinary Lithogenic Factors of Obese Patients With Kidney Stones
The objective of this study is to evaluate the influence of low-calorie diet on serum and urinary metabolic parameters of obese adults with urinary calculi and lithogenic metabolic abnormalities.
- Trial name
- NCT02690662
- Testing
- Hypocaloric diet
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Kidney Stone, Nephrolithiasis
Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of Surgeon Behavior and Post-operative Outcomes
The goal of this study is to evaluate the influence of real-time intrarenal pressure measurement availability on surgeons' behavior during ureteroscopy while using the ureteroscope LithoVue Elite.
- Trial name
- ELITE (NCT06576661)
- Testing
- INTRARENAL PRESSURE MONITORING VISIBLE
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Kidney Stone
Adjunct Inversion for Lower Pole Stone
This is a randomized controlled trial comparing extracorporeal shockwave lithotripsy (ESWL) with and without simultaneous adjunct controlled inversion therapy in the treatment of lower pole caliceal stone.
- Trial name
- NCT01852669
- Testing
- Inversion, Shock Wave Lithotripsy, Hydration
- Volunteers
- 140 people
- Sponsor
- Monash University
Kidney Stones
Alfuzosin for Medical Expulsion Therapy of Ureteral Stones
The goal of this study is to conduct a prospective controlled trail of four currently approved Department of Defense (DOD) - formulary medications for use as medical expulsion therapy (MET) for kidney stones.
- Trial name
- MET (NCT00713739)
- Testing
- Alfuzosin, nifedipine, doxazosin
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University
UTI, Stone, Kidney
Evaluation of Novel Disposable Flexible Ureteroscope for the Treatment of Renal Calculi
This study is designed to provide an evaluation of currently available disposable flexible ureteroscopes in real-world conditions.
- Trial name
- NCT05646069
- Testing
- Storz Flex-XC1 Disposable Flexible Ureteroscope, Storz Flexible Digital Ureteroscope
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Northwestern University
Nephrolithiasis, Kidney Stone
Observational Approach Versus Surgical Intervention for Stones
The aims of the Observational Approach versus Surgical Intervention for Asymptomatic Stone (OASIS) trial are: 1) to determine whether observation compared to upfront surgery results in less healthcare-related life disruption due…
- Trial name
- OASIS (NCT07718802)
- Testing
- Surgery, Observation
- Where
- 4 sites in United States
- Volunteers
- 1,658 people
- Sponsor
- Children's Hospital of Philadelphia
Kidney Calculi, Ureteral Calculi
Impact of Humid-Heat on Gut-Tryptophan-Stone Pathway
Investigating the differences in gut microbiota composition and tryptophan metabolite levels between kidney stone patients and healthy individuals, with special focus on: 1.
- Trial name
- NCT07043374
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Kidney Stone
Comparison of the Efficacy of Flexible Ureteroscope and Percutaneous Nephroscopic Surgery in the Treatment of 2-4cm Kidney Stones
Urolithiasis is a common disease in urology. With the continuous progress of science and technology, the treatment of kidney lithiasis has undergone revolutionary changes, and the previously commonly used open surgical lithotomy…
- Trial name
- NCT06507176
- Testing
- flexible ureteroscopic lithotripsy, percutaneous nephrolithotomy
- Where
- China
- Volunteers
- 224 people
- Sponsor
- The First Hospital of Jilin University
Kidney Stones, Nephrolithiasis
Effect of Diet Orange Soda on Urinary Lithogenicity
Beverages containing citrate may be useful in increasing urine citrate content and urine pH. Such changes in urine chemistry could help prevent kidney stones. Diet orange soda has more citrate than other similar beverages.
- Conditions
- Kidney Stones, Nephrolithiasis, Urolithiasis
- Trial name
- NCT01330940
- Testing
- Orange soda
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- VA New York Harbor Healthcare System
Urinary Lithiasis
Evaluation of the Safety and Performance of the Hydrustent® Biodegradable Hydrogel Ureteral Stent
The goal of this clinical investigation is to evaluate whether the Hydrustent® medical device is safe and if maintain the urinary flow inside the ureter in adults.
- Trial name
- Hydrustent (NCT06719089)
- Testing
- Biodegradable double loop ureteral stent, PolyUrethane Double Loop Ureteral Stent
- Where
- 4 sites in Portugal
- Volunteers
- 134 people
- Sponsor
- Hydrumedical
Kidney Stones
Acoustic Impedance Matching in ESWL Coupling
The purpose of this study is to investigate the effect of different salt concentrations (tonicity) in the coupling fluid used during Extracorporeal Shock Wave Lithotripsy (ESWL).
- Trial name
- NCT07585435
- Testing
- Hypotonic degassed water coupling, Isotonic (0.9% NaCl) coupling, Hypertonic (3% NaCl) coupling
- Where
- Turkey (Türkiye)
- Volunteers
- 294 people
- Sponsor
- Konya City Hospital