Clinical trials: Renal Stone Disease
Urolithiasis
Kidney Stone Calculator
Urolithiasis is a frequent pathology, for which flexible ureteroscopy with endocorporeal laser lithotripsy has become the most frequently used surgical treatment.
- Trial name
- KSC (NCT05707988)
- Where
- France
- Volunteers
- 223 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kidney Stone
CT-Ultrasound Fusion in Guiding PCNL Puncture
Kidney stone is a common urological disease. Percutaneous nephrolithotomy (PCNL) is an important method for the treatment of kidney stones.
- Trial name
- NCT04645472
- Testing
- CT-Ultrasound
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Zhenyu Wu
Kidney Stone, Surgery
Regional Erector Spinae Analgesic Block vs Standard of Care Undergoing Percutaneous Nephrolithotomy
The purpose of this study is to determine if adding a spinal block (medicine that will numb parts of the body to block pain) along with standard pain control at the incision site will decrease the need for narcotics for pain…
- Trial name
- NCT04663269
- Testing
- 4mg PF Dexamethasone, Control Test
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Indiana University
Kidney Stone, Nephrolithiasis
Pediatric KIDney Stone (PKIDS) Care Improvement Network
The goals of this study are to improve the ability of pediatric patients and their caregivers to select surgical treatment options for kidney stones and to enable urologists to use techniques that result in the best outcomes for…
- Trial name
- PKIDS (NCT04285658)
- Testing
- Ureteroscopy, Percutaneous Nephrolithotomy, Shock Wave Lithotripsy
- Where
- 31 sites in United States, Canada
- Volunteers
- 1,290 people
- Sponsor
- Children's Hospital of Philadelphia
Renal Calculi
Effects of the Use of Adjuvant Drugs After Extracorporeal Shockwave Lithotripsy (ESWL) in Renal Calculus
The investigators objective is to study if some drugs can improve the success rate of extracorporeal shockwave lithotripsy for renal stones.
- Trial name
- NCT01215708
- Testing
- Tamsulosin
- Where
- Brazil
- Volunteers
- 136 people
- Sponsor
- University of Sao Paulo General Hospital
Kidney Calculi, Kidney Stone
Are the Stone Density and Location Useful Parameters for Small Kidney Stones?
The investigators aimed to evaluate whether these parameters could be guides for us in the selection of RIRS or Mini-PNL procedures in kidney stones that are smaller than 2 cm.
- Trial name
- NCT03503539
- Testing
- Mini percutaneous nephrolithotomy, Retrograde intrarenal surgery
- Volunteers
- 60 people
- Sponsor
- Abant Izzet Baysal University
Urolithiasis, Kidney Calculi
Safety and Efficacy of Traditional Versus Flexible and Navigable Suction Sheath in Retrograde Intra-Renal Stone Surgery
This study compares two techniques used during RIRS for the treatment of kidney stones measuring up to 20 mm. During RIRS, surgeons often use a device called a UAS to help pass instruments into the urinary system and to assist…
- Conditions
- Urolithiasis, Kidney Calculi, Nephrolithiasis
- Trial name
- NCT07286071
- Testing
- Retrograde intrarenal surgery using a ureteral access sheath with suction, Retrograde intrarenal surgery using a traditional ureteral access sheath
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Kidney Stones
Use of the PercSys MicroStent Device to Alleviate Ureteral Stone Symptoms and Hydronephrosis
Kidney stones cause severe pain. Patients with a stone lodged in the ureter (the tube that drains the bladder), require urgent treatment with a stent to relieve the blockage.
- Trial name
- NCT01637519
- Where
- 2 sites in Canada
- Volunteers
- 9 people
- Sponsor
- University of British Columbia
Renal Calculi, Urinary Calculi
Break Wave(TM) Extracorporeal Lithotripter First-in-Human Study
This is a prospective, open-label, multi-center, single-arm (non-randomized) study to assess the safety and effectiveness of breaking stones in the upper urinary tract using the SonoMotion Break Wave technology.
- Trial name
- NCT03811171
- Testing
- Break Wave extracorporeal lithotripsy
- Where
- 6 sites in United States, Canada
- Volunteers
- 70 people
- Sponsor
- SonoMotion
Urologic Injuries, Disorder of Urinary Stent
Indwelling Stent Discoloration Project
The aim of this study is to identify the root cause for the significant discolouration of Boston Scientific Percuflex based stents.
- Conditions
- Urologic Injuries, Disorder of Urinary Stent, Kidney Calculi, Urinary Tract Obstruction Due to Specified Cause
- Trial name
- NCT02007980
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Nephrolithiasis, Calcium Oxalate Kidney Stones
Vitamin E Supplementation Effect in Management of Calcium Oxalate Crystals
Nephrolithiasis is a condition characterized by the formation of crystalline stones in the urinary system. The most common component of these stones is calcium oxalate.
- Trial name
- NCT07715643
- Testing
- Control Group T0, Intervention Group T1, Intervention Group T2
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Lahore
Nephrolithiasis, Ureterolithiases
Validation of Low Dose CT for Diagnosis of Urolithiasis
The investigators have developed an extremely low dose renal computed tomography (CT) protocol that on preliminary testing has an effective dose in the range of a single view abdominal radiograph.
- Trial name
- NCT03656913
- Testing
- Extremely low dose CT
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Kidney Calculi
Initial Clinical Experience With the MONARCH Platform, Urology for the Treatment of Kidney Stones
The purpose of this study is to collect descriptive performance data using the MONARCH Platform, Urology (a novel robotic device) to perform mini-percutaneous nephrolithotomy (kidney stone removal) procedures.
- Trial name
- NCT05835323
- Testing
- Robotic-assisted mini-PCNL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Auris Health, Inc.
Kidney Stone, Calculi, Renal
Our Stone Fixation Technique to Improve Efficiency and Results of Peumatic Lithotripsy in Suction Mini-PCNL.
Prospective study to assist safty and efficieny of our technique of using peumatic lithotripsy with suction mini-pcnl.
- Trial name
- NCT07328659
- Testing
- Peumatic lithotripsy in mini-pcnl
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Yasser Gamil Elnagar
Kidney Stone
Ultrasound-guided Transmuscular Quadratus Lumborum Block for Percutaneous Nephrolithotomy
Patients undergoing percutaneous nephrolithotomy (PNL) suffer from acute postoperative pain, despite a multimodal analgesic regime.
- Trial name
- NCT02818140
- Testing
- Ropivacaine TQL block, Saline TQL block, Ropivacaine
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
Kidney Calculi
Fluoroscopy Activation Interval in SWL
Shock wave lithotripsy (SWL) is a noninvasive method widely used as the first step in treating stone disease. This study aimed to reduce radiation exposure to patients and practitioners during SWL sessions by extending the…
- Trial name
- NCT06689683
- Testing
- Shock wave lithotripsy
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people
- Sponsor
- Lütfi Kırdar City Hospital
Pediatric Kidney Disease
Ultrasonic vs. Fluoroscopic Guided PNL in Pediatric Renal Stones
Percutaneous Nephrolithotomy (PNL) was accepted as a treatment modality for large renal stones since 1980. Although radiation exposure during PNL is within the safe limits for expert endourologist, the mutagenic hazard is still…
- Trial name
- NCT03250559
- Testing
- Percutaneous nephrolithotomy
- Where
- Egypt
- Volunteers
- 6 people
- Sponsor
- Assiut University
Ureteral Calculi
The Predictive Value of Ureteral Jet Assessment With Ultrasound in Patients Presenting With Acute Renal Colic
This is a single institution, prospective study to evaluate the prognostic significance of renal and bladder ultrasound with ureteral jet assessment and its utility to evaluate the spontaneous stone passage rate of ureteral…
- Trial name
- NCT02577146
- Testing
- renal and bladder ultrasound with ureteral jet assessment
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Washington University School of Medicine
Kidney Stone
Evaluation of Pain Before and After Removal of Non-obstructive Kidney Stones
Pain associated with renal stone disease is typically caused by an obstructing stone that obstructs the flow of urine, which results in renal collecting system dilatation.
- Trial name
- ENORC (NCT03657667)
- Testing
- Ureteroscopy
- Where
- 9 sites in United States, Canada
- Volunteers
- 43 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Renal Stone, Pediatric
Flexible Ureteroscopy Versus Mini- Percutaneous Nephrolithotomy in Management of Pediatric Renal Stones Less Than 2 cm
This single-center, prospective, two-arm randomized controlled trial included 58 patients younger than 18 years who were allocated 1:1 to Mini-PCNL or FURS between June 2023 and December 2024.
- Trial name
- NCT07870200
- Testing
- Group A :Flexible ureteroscope group, Group B : Mini perc group
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Elsayed Abdelhalim Elsayed