Clinical trials: Renal Transplant Patient
Kidney Transplant
A Study Of CP-690,550 In Stable Kidney Transplant Patients
This was a Phase 1 dose escalation study to evaluate the safety, tolerability and pharmacokinetics of 28-day treatment of CP-690,550 in stable renal allograft recipients.
- Trial name
- NCT01710033
- Testing
- CP-690,550 5 mg BID, CP-690,550 15 mg BID, CP-690,550 30 mg BID
- Where
- 11 sites in United States
- Volunteers
- 28 people
- Sponsor
- Pfizer
Renal Transplantation
Safety and Efficacy Study of Rituximab in Renal Transplantation
Current strategies for the medical management of transplant patients are largely focused on the prevention and treatment of T-lymphocyte mediated processes.
- Trial name
- NCT00255593
- Testing
- rituximab
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Karolinska University Hospital
HIV-1 Infection, Chronic Renal Insufficiency
Renal Transplantation and Raltegravir in HIV-Infected Patients
The aim of this study is to evaluate the incidence of acute renal graft rejection 6 months after transplantation in HIV-infected patients under three antiretroviral drugs regimen including Raltegravir.
- Trial name
- ANRS153TREVE (NCT01453192)
- Testing
- Raltegravir
- Where
- 14 sites in France
- Volunteers
- 27 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Disorder Related to Transplantation, Virus Diseases
Replacement of Lamivudine by Telbivudine to Improve Renal Function
Nephrotoxicity is one of the adverse effects of lamivudine and dosage of lamivudine has to be reduced if patients' renal function is insufficiency. Telbivudine may improve glomerular filtration rate.
- Conditions
- Disorder Related to Transplantation, Virus Diseases, Injury Due to Exposure to External Cause
- Trial name
- NCT02447705
- Testing
- telbivudine
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Organ or Tissue Transplant; Complications
Pharmacokinetic Study of ENVARSUS in Adult De-novo Kidney Transplant Patients
Open-label, multicentre, randomized clinical trial to compare the pharmacokinetics of ENVARSUS® tablets and ADVAGRAF® capsules administered once daily in adult de-novo kidney transplant patients.
- Trial name
- NCT02500212
- Testing
- ENVARSUS®, ADVAGRAF®
- Where
- 7 sites in France
- Volunteers
- 75 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
End-stage Heart Failure
Acute Reno-Cardiac Action of Dapagliflozin In Advanced Heart Failure Patients on Heart Transplant Waiting List
In the DAPA-HF trial, the use of dapagliflozin, an inhibitor of sodium-glucose cotransporter 2 (SGLT2), reduced significantly the risk of worsening heart failure or death from cardiovascular causes compared to placebo among…
- Trial name
- ARCADIA-HF (NCT04782245)
- Testing
- Dapagliflozin 10mg
- Where
- France
- Sponsor
- Hospices Civils de Lyon
End Stage Renal Failure on Dialysis
Data Collection Registry of the HeRO Graft for End Stage Renal Disease Patients Receiving Hemodialysis
Data Collection Registry of the HeRO Graft for End Stage Renal Disease Patients Receiving Hemodialysis
- Trial name
- NCT02164175
- Testing
- HeRO Graft implant for dialysis access
- Where
- 3 sites in United States
- Sponsor
- Merit Medical Systems, Inc.
End-Stage Renal Disease Requiring Haemodialysis, Bladder Dysfunction
IMPACT OF DIALYSIS DURATION AND DIURESIS ON BLADDER CAPACITY AND COMPLIANCE IN END STAGE RENAL DISEASE PATIENTS AWAITING RENAL TRANSPLANT
Patients with end-stage renal disease (ESRD) who are on dialysis for a long time may experience bladder problems as their urine output decreases and normal bladder filling is lacking.
- Trial name
- ESRD (NCT07570771)
- Testing
- Observational Assessment
- Where
- Pakistan
- Volunteers
- 87 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Impaired Glucose Tolerance, Kidney Transplantation
Glucose Control in Pre-Diabetic Renal Transplant Patients
Development of New-Onset Diabetes after Transplantation (NODAT) is common and serious complication after kidney transplantation.
- Trial name
- GCPD (NCT01346254)
- Testing
- Vildagliptin, Pioglitazone, Life-Style Modification
- Where
- Austria
- Volunteers
- 51 people
- Sponsor
- Marcus Saemann
Kidney Transplant; Complications, Cardiovascular Diseases
Romanian Kidney Transplant Cardiovascular Risk Registry
Kidney transplantation (KT) represents the best treatment for patients with end-stage kidney disease, being associated with improved outcomes and reduced mortality.
- Trial name
- ROKET-CV (NCT04451356)
- Testing
- Bioimpedance Spectroscopy, Arterial Stiffness, Echocardiography
- Where
- Romania
- Volunteers
- 300 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Tooth Loss, Disorder Related to Renal Transplantation
Osseointegrated Dental Implants in Kidney Transplanted Patients
The evaluation of the bone, using several techniques and on several aspects will be the purpose to study the possible impact of the kidney transplant (and, extensively, the pre-transplant dialysis, the organ replacement and the…
- Trial name
- NCT02513602
- Testing
- Dental implant insertion
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- University of Trieste
Renal Insufficiency, Chronic, Organ Graft
Therapeutic Education of Chronic Renal or Renal Transplant Patient in the Management of EPO Injections
In chronic kidney disease, ESAs (Erythropoiesis-stimulating agents) are used to treat anemia. This anemia is due to decreased renal production of erythropoietin (EPO), a hormone that stimulates the production of red blood cells…
- Trial name
- SELFEPO (NCT03481686)
- Testing
- Patients with injections of ESA
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Rennes University Hospital
Covid19, Kidney Transplant Infection
Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience From the Middle East
Methods: Out of 2000 kidney transplant recipients in our center in Kuwait, collecting data was started for all COVID-19-positive kidney transplant recipients till August 2020.
- Conditions
- Covid19, Kidney Transplant Infection, Risk Factor, Cardiovascular, Immunosuppression
- Trial name
- OMC-KTR (NCT04542954)
- Testing
- Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience from the Middle East
- Where
- Kuwait
- Volunteers
- 104 people
- Sponsor
- Hamid Al-Essa Organ Transplant Center
Kidney Transplant Rejection, Kidney Transplant; Complications
Added Value of 18 FDG Pet-scanner in Diagnosis and Management of Subclinical Rejection in Kidney Transplant Patients
The renal biopsy (RB) represents the gold-standard for the diagnosis of acute renal transplant rejection (AR), and allows early verification of a so-called "subclinical" rejection, ie without any clinical or biological…
- Trial name
- NCT04702022
- Testing
- 18FDG PET / CT
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University of Liege
De Novo Transplant Disease
Prospective Study to Measure Vascular Parameters (Ancillary Study of ADEQUATE)
The purpose of this study is to compare parallel-group effects between 4 months and 12 months post-transplantation 2 values of target residual concentrations of Advagraf on vascular parameters in de novo renal transplant patients.
- Trial name
- ADEQUATEartère (NCT02154854)
- Testing
- Tacrolimus targeted half-dose, Tacrolimus targeted plain dose
- Where
- 11 sites in France
- Volunteers
- 104 people
- Sponsor
- University Hospital, Tours
SARS-CoV-2 Infection, Active Immunization
Saxon SARS-CoV-2 Infection and Vaccination Study in Dialysis Patients, Solid Organ Recipients and Staff
To investigate short- (3 and 8 weeks) and long-term (6, 9, 12, and 18 months) immune protection or response at the humoral and cellular levels before and after SARS-CoV-2 infection or vaccination in patients with moderately…
- Conditions
- SARS-CoV-2 Infection, Active Immunization, Immune Response, Immunosuppression
- Trial name
- DIA-Vacc (NCT04799808)
- Where
- Germany
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Kidney Transplant
A Prospective, Open Label Study of CERtican in KIdney Transplantation
A prospective, open label study of CERtican in KIdney transplantation
- Trial name
- CERKI (NCT01594268)
- Testing
- Everolimus
- Where
- 4 sites in South Korea
- Volunteers
- 54 people
- Sponsor
- Novartis Pharmaceuticals
Kideny Transplant Recipients With High Cardiovascular Risk Score
PCSK 9 Inhibition as Secondary Prevention in Renal Transplant Patients
From this randomized controlled study, we aim to: A.Do do cardiovascular risk stratification of renal transplant recipients who are followed up in Hamed Al-Essa organ transplant center of Kuwait. B.
- Trial name
- NCT04665830
- Testing
- Evolocumab
- Where
- Kuwait
- Volunteers
- 200 people
- Sponsor
- Hamid Al-Essa Organ Transplant Center
SIOD, Cystinosis
Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor
This is a single center, non-randomized, non-controlled open-label phase 1b/2a trial of performing sequential αβdepleted-HSCT and KT in patients requiring KT to prevent kidney rejection post-KT, in the absence of any post-KT…
- Conditions
- SIOD, Cystinosis, FSGS, SLE Nephritis
- Trial name
- NCT05508009
- Testing
- Cyclophosphamide 1200 mg/Kg, Fludarabine, Cyclophosphamide 100 mg/Kg
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Alice Bertaina
Kidney Transplantation, Exercise
Efficiency of a Whole Body Vibration Training Program in Adult Renal Transplanted Patients
Evaluate the effectiveness of a Whole body vibration training program on quadriceps muscle strength, functional capacity and respiratory muscle strength in adult renal transplant recipients
- Trial name
- NCT03120377
- Testing
- Platform
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco