Clinical trials: Renal Transplant Recipient
Heart Transplant Patients, Kidney Transplant Patients
Multidisciplinary Non-Pharmacological Intervention to Improve Quality of Life in Solid Organ Transplant Recipients
This is a single-center interventional study aimed at evaluating the feasibility of a multidisciplinary non-pharmacological approach based on acupuncture, telerehabilitation-based physical rehabilitation, and brain health…
- Conditions
- Heart Transplant Patients, Kidney Transplant Patients, Lung Transplant, Liver Transplanted Patients
- Trial name
- TAO (NCT07870811)
- Testing
- Acupuncture, Telerehabilitation-Based Physical Rehabilitation, Psychological Support Program
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- The Mediterranean Institute for Transplantation and Advanced Specialized Therapies
Renal Transplanted Recipients
Validity and Reliability of 6 Minute Stepper Test in Kidney Transplant Recipients
The aim of our study was to investigate the validity and reliability of the 6 minute stepper test in kidney transplant recipients.
- Trial name
- NCT06707792
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hacettepe University
Skin Cancer, Kidney Transplant Recipients
Pilot Trial of Supplemental Vitamin A and Nicotinamide
The goal of this clinical trial is to assess the feasibility and safety of oral nicotinamide (NAM; a derivative of vitamin B3 [niacin]) and vitamin A in a high-risk population of kidney transplant recipients with a history of…
- Trial name
- NCT05702398
- Testing
- Vitamin A, Nicotinamide
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rhode Island Hospital
Graft Rejection, Kidney Transplantation
Study Comparing the Safety and Efficacy of Belatacept With That of Cyclosporine in Patients With a Transplanted Kidney
The purpose of this study is to determine whether treatment with Belatacept (BMS-224818) is as efficacious as treatment with cyclosporine at preventing acute rejection and with a superior safety/tolerability profile (better…
- Conditions
- Graft Rejection, Kidney Transplantation, Renal Transplantation
- Trial name
- NCT00035555
- Testing
- Belatacept, Cyclosporine, Mycophenolate mofetil (MMF)
- Where
- 12 sites in United States
- Volunteers
- 230 people
- Sponsor
- Bristol-Myers Squibb
Hyperglycemia
Treat-to-target Trial of Basal Insulin in Post-transplant Hyperglycemia
Treat-to-target trial of basal Insulin in Post-transplant hyperglycemia (TIP): efficacy and safety of a novel protocol in renal transplant recipients receiving a tacrolimus-based immunosuppression DESCRIPTION: A prospective…
- Trial name
- TIP (NCT00830297)
- Testing
- Insulatard (long-acting insulin), Conventional
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Marcus Saemann
Renal Transplant Recipients
Research Study of ATG and Rituximab in Renal Transplantation
The purpose of this study is see if a combination of two drugs, (ATG and rituximab), given at the time of the transplant surgery, will help reduce or eliminate the need for long term immunosuppressive medication.
- Trial name
- RESTARRT (NCT01318915)
- Testing
- ATG, Rituximab, Tacrolimus
- Where
- 6 sites in United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Kidney Transplant Rejection
PROACT Pilot Trial
Kidney transplantation is considered the best option to treat end-stage kidney disease, but the recipient's immune system may respond with rejection to the transplanted organ, leading to permanent kidney damage and failure.
- Trial name
- NCT06564649
- Testing
- CXCL10 Monitoring at clinical frequency
- Where
- 3 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Kidney Transplantation
Concentration Controlled Everolimus With Reduced Dose Cyclosporine Versus Mycophenolate Mofetil With Standard Dose Cyclosporine in de Novo Renal Transplant Adult Recipients Treated With Basiliximab and Corticosteroids
The 12 Month Core Study (CRAD001A1202) was designed to evaluate the efficacy and safety comparing concentration-controlled everolimus (1.5 mg/day starting dose) with reduced dose cyclosporine and corticosteroids versus 2 g/day…
- Trial name
- NCT00658320
- Testing
- Everolimus, Mycophenolate mofetil (MMF), Basiliximab
- Where
- Japan
- Volunteers
- 122 people
- Sponsor
- Novartis
Kidney Transplant, Urinary Tract Infection(UTI)
Antibiotics for Kidney Transplant Recipients
The goal of this clinical trial is to learn if a common antibiotic called trimethoprim-sulfamethoxazole (TMP-SMX) can help prevent urinary tract infections (UTIs) in children and young adults who recently had a kidney transplant.
- Conditions
- Kidney Transplant, Urinary Tract Infection(UTI), Antibiotic Prophylaxis, Remote Patient Monitoring
- Trial name
- TASK (NCT07106125)
- Testing
- Trimethoprim-Sulfamethoxazole (TMP-SMX), Usual Care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Liver Transplantation
REnal Function in Liver Transplantation: Everolimus With Calcineurin Inhibitor (CNI)-Sparing sTrategy
The purpose of this study was, starting from the Italian clinical practice in liver transplantation, to optimize the immunosuppressive therapy, considering specific patient characteristics as alcoholic cirrhosis, hepatitis C…
- Trial name
- REFLECT (NCT02115113)
- Testing
- Everolimus, Tacrolimus
- Where
- 14 sites in Italy
- Volunteers
- 78 people
- Sponsor
- Novartis Pharmaceuticals
Kidney Transplant Rejection
The TOGETHER Project - Kidney RNA-seq Validation
The researchers are trying to develop a way to measure the risk of rejection through the validation of a blood test.
- Trial name
- TOGETHER (NCT03874299)
- Where
- 3 sites in United States
- Volunteers
- 302 people
- Sponsor
- Mayo Clinic
Chronic Allograft Nephropathy
Calcineurin Inhibitor Minimisation in Renal Transplant Recipients With Stable Allograft Function
The purpose of this trial is to ascertain whether the withdrawal of calcineurin inhibitors (CNI) will lead to less kidney transplant damage when compared with minimisation.
- Trial name
- CNIM-SRT (NCT00541814)
- Testing
- Cyclosporine
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- University Hospital Birmingham
Polyneuropathies
Sensory Neuropathy Scores Validated by Quantitative Sensory Testing and Nerve Conduction Studies for Kidney Transplant Recipients
Sensory polyneuropathy is one of the most prevalent neurological disorders and a common finding in kidney transplant recipients (KTR).
- Trial name
- SENS (NCT04664426)
- Where
- Netherlands
- Volunteers
- 196 people
- Sponsor
- University Medical Center Groningen
Kidney Disease, Chronic, Transplant Complication
Plant-based Diet for Kidney Transplant Recipients
The goal of this clinical trial is to evaluate cardiometabolic and inflammatory parameters in kidney transplant recipients after transitioning to a plant-based diet (PBD).
- Conditions
- Kidney Disease, Chronic, Transplant Complication, Hypertension, Diabetes Mellitus
- Trial name
- NCT06186843
- Testing
- Plant-based diet
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- George Washington University
Renal Transplant Rejection
Dose Adjustment of Tacrolimus Based on Home Sampling in Renal Transplant Recipients
Repeated 12-hour pharmacokinetic (PK) investigations in renal transplant recipients for parallel sampling of standard venous bloods samples and finger prick micro samples (Mitra tips).
- Trial name
- TacDrop (NCT03512431)
- Testing
- Micro sampling
- Where
- Norway
- Volunteers
- 27 people
- Sponsor
- Oslo University Hospital
Kidney Transplant Recipients
Exercise and Diet Effects in Reducing Cardiovascular Risk in Kidney Transplant Recipients
The goal of this clinical trial is to assess whether, over an observation period of 3 years, there is a reduction in cardiovascular risk, and the extent of this reduction, in a group of adult kidney transplant patients undergoing…
- Trial name
- KT-LIFESTYLE (NCT06806670)
- Testing
- lifestyle intervention
- Where
- Italy
- Volunteers
- 275 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Covid19, Kidney Transplant Infection
Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience From the Middle East
Methods: Out of 2000 kidney transplant recipients in our center in Kuwait, collecting data was started for all COVID-19-positive kidney transplant recipients till August 2020.
- Conditions
- Covid19, Kidney Transplant Infection, Risk Factor, Cardiovascular, Immunosuppression
- Trial name
- OMC-KTR (NCT04542954)
- Testing
- Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience from the Middle East
- Where
- Kuwait
- Volunteers
- 104 people
- Sponsor
- Hamid Al-Essa Organ Transplant Center
Kidney Transplantation, Anemia
Effects of Anemia Correction on Vascular and Monocyte Function in Renal Transplant Recipients
Correction of anaemia in renal transplant recipients by parenteral application of recombinant erythropoietin and if necessary iron will improve large artery function (endothelial function and elasticity), as assessed by…
- Trial name
- NCT00204334
- Testing
- darbopoeitin
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Muenster
Kidney Transplant Recipients
The Effects of Physical Activity Behavior Change in Kidney Transplant Recipients
The aim of this study is to investigate the effects of physical activity program according to motivational interviewing based on the Transtheoretical Model on cardiovascular risk factors, physical activity level, physical…
- Trial name
- NCT05425498
- Testing
- Physical activity program
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Dokuz Eylul University
Organ Grafts
Tacrolimus Minimization in Kidney Transplant Recipients Selected According to the AGORA Algorithm for Their Low Immunological Risk and Medium-term Graft Failure
The goal of this clinical trial is that validation of the non-invasive biomarkers of the AGORA algorithm should make it possible to select patients with a very low immunological risk of graft failure to authorize safe…
- Trial name
- AGORAC (NCT06235892)
- Testing
- TACROLIMUS
- Where
- 3 sites in France, Norway and 1 more
- Volunteers
- 300 people
- Sponsor
- Nantes University Hospital