Clinical trials: Renin Hypertension
Glomerulonephritis, IGA, Hypertension
A Prospective Study of the Kidney Protective Effect of Aliskiren in Hypertensive Patients With IgA Nephropathy
The purpose of this study is to evaluate the effect of aliskiren, a novel direct rennin inhibitor, on renal function and progress of renal disease in hypertensive patients with IgA nephropathy.
- Trial name
- NCT01184599
- Testing
- aliskiren
- Where
- 4 sites in Japan
- Volunteers
- 30 people
- Sponsor
- Kagawa University
Preeclampsia, Hypertension
Hypertension and Urine Protease Activity in Preeclampsia
Preeclampsia (PE) is a common disorder of pregnancy that complicates 4-7% of all pregnancies. It is a serious condition with acute proteinuria and hypertension and varying degrees of edema after 20 weeks of gestation.
- Conditions
- Preeclampsia, Hypertension, Proteinuria, Pregnancy
- Trial name
- HUPP (NCT01828138)
- Testing
- Sodium
- Where
- Denmark
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Cardiovascular Diseases, Heart Diseases
Renin and Prorenin in Pregnancy
To determine the role of the prorenin-renin-angiotensin-aldosterone system (RAAS) in normal and hypertensive pregnancy.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Pregnancy Toxemias
- Trial name
- NCT00005207
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypertension, Diabetes Mellitus
Comparison of Amlodipine and Aliskiren in Diabetic Hypertensive Patient With Blood Pressure Not Controlled by Losartan
Assess if aliskiren is capable of enhancing vascular stiffness and endothelial function and compare theses effects and renin activity and concentration to those obtained with a calcium channel blocker, amlodipine, in patients…
- Trial name
- NCT01409408
- Testing
- Aliskiren, Amlodipine
- Where
- Brazil
- Sponsor
- Hospital Universitario Pedro Ernesto