Clinical trials: Reproduction
PrEP for Conception Purposes
PrEPception: Expanding Assisted Reproductive Options for Serodiscordant Couples
The purpose of this study is to observe patient response to current clinical practice utilizing TRUVADA (emtricitabine and tenofovir disoproxil fumarate) for Pre-Exposure Prophylaxis (PrEP) amongst HIV serodiscordant couples…
- Trial name
- NCT02233192
- Where
- 4 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
PCOS
Effect of Acupuncture on Anti Mullerian Hormone and Assisted Reproduction Outcome in PCOS Patients Undergoing IVF
Acupuncture at follicular phase of the cycle may improve the pregnancy rate. This study aims to compare assisted reproduction outcome between two groups of PCOS patients underwent IVF, one group received acupuncture and other…
- Trial name
- NCT01778621
- Testing
- Acupuncture(Hwato®)
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Amina Altutunji
Environmental Enteric Dysfunction (EED), Malnutrition
The Maternal EED Study
Undernutrition among women of reproductive age is more common in South Asia than in any other region. In South Asia, the prevalence of maternal undernutrition varies between 10 and 40%.
- Conditions
- Environmental Enteric Dysfunction (EED), Malnutrition, Women of Reproductive Age, Gut Microbiota
- Trial name
- NCT05862363
- Testing
- Microbiota-directed balanced energy protein (MD-BEP), Ready-to-use supplementary food-balanced energy protein (RUSF-BEP), Esophagogastroduodenoscopy (EGD)
- Where
- Bangladesh
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Pain
Study of Pain Control With Hormonal IUS Insertion
This study aims to compare pain during insertion of the Skyla® IUS using a 100mm visual analog scale (VAS) among 92 young women aged 14 to 22 years randomized to receive a paracervical (n=46) block versus a sham paracervical…
- Trial name
- SOPHI (NCT02352714)
- Testing
- Paracervical Nerve Block
- Where
- 3 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Pregnancy, Smoking
Self-Monitoring of Carbon Monoxide to Enhance Reproductive Outcomes in Women
Our goal is to study self-monitoring of smoking as a means to reduce smoking in pregnant women. Investigators hypothesize that more regular self-monitoring, text messages and feedback as provided by home carbon monoxide…
- Conditions
- Pregnancy, Smoking, Smoking Cessation
- Trial name
- NCT02246114
- Testing
- piCO+ Smokerlyzer® monitor, Text messages
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Maternal Care Patterns
Effectiveness and Acceptability of Availing Skilled Birth Attendance (SBA) Services Through Community Reproductive Health Nurses (CORN) to a Household Level at Rural Communities of Ethiopia; A Cluster Community Trial in Gedeo Zone, SNNPR
Rationale: Every year, 287,00 million women, and 3.1 million neonates continue to die, and the majority of these deaths have been identified as being avoidable.
- Trial name
- CORN (NCT02501252)
- Testing
- trained midwives and nurses working in the community to provide skilled SBA services
- Where
- Ethiopia
- Volunteers
- 2,670 people, healthy volunteers welcome
- Sponsor
- Dilla University
Contraception
An Intervention Delivered by App Instant Messaging to Increase Use of Effective Contraception Among Young Women in Bolivia
This randomised controlled trial will establish the effect a contraceptive intervention delivered by mobile phone app instant messaging on use of effective contraception in Bolivia.
- Trial name
- NCT02905526
- Testing
- Contraceptive instant messages, Mobile phone app
- Where
- Bolivia
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Health, Pregnancy
Use of Mobile Technology by Community-Based Health Workers to Promote Maternal and Child Health in Bihar, India
This study is designed to evaluate the impact of use of mobile technology by community-based health workers on health-promoting behaviors among women related to reproductive, maternal, newborn and child health and nutrition in…
- Conditions
- Health, Pregnancy, Infant, Nutrition
- Trial name
- ICT-CCS (NCT03406221)
- Testing
- Information Communication Technology Continuum of Care Service, Control Condition
- Volunteers
- 3,112 people
- Sponsor
- Stanford University
Menstrual Disorder, Premature Ovarian Failure
The Effect of HPV Vaccine on Menstrual Cycle in Women of Reproductive Age
Cervical cancer is one of the most common cancer in women, making it the fourth largest cause of female cancer mortality worldwide.
- Trial name
- NCT05838157
- Testing
- prophylactic HPV vaccine(bivalent HPV、quadrivalent HPV、9-valent HPV)
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Reproductive Health, Abortion
Effects of Prior Induced Termination of Pregnancy on Complications and Pregnancy Outcomes.
A prospective multicenter cohort study to evaluate effects of prior induced termination of pregnancy on complications and pregnancy outcomes.
- Trial name
- NCT04183829
- Testing
- induced termination of pregnancy
- Where
- 12 sites in China
- Volunteers
- 20,000 people
- Sponsor
- National Research Institute for Family Planning, China
Energy Deficiency Due to Short-term Fasting, Hormonal Contraception
Energy Deficiency on Hormones in Contraceptive Users
The purpose of the present study is to characterize the endocrine and metabolic responses to a modest, short-term energy deficiency (~250 kcal/day) across the menstrual cycle in recreationally active women using different…
- Trial name
- NCT07651800
- Testing
- Energy Deficiency of approximately ~250 kcal/day
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Southern California
Infertility
Swanson-Based Supportive Care for Infertility Stress and Coping in Couples Undergoing ART
The goal of this clinical trial is to learn if supportive care based on Swanson's Caring Theory can reduce stress and improve coping in couples undergoing infertility treatment with assisted reproductive treatment (ART)…
- Trial name
- NCT07557069
- Testing
- Swanson Caring Theory-based supportive care
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ondokuz Mayıs University
Breast Cancer, Genitourinary Cancer
Inflammatory Response and Tissue Fibrosis/ Lymphatico-venous Bypass
The goal of this clinical research study is to measure the amount of inflammatory proteins inside the body before and after lymphatico-venular bypass surgery.
- Conditions
- Breast Cancer, Genitourinary Cancer, Malignant Female Reproductive System Neoplasm, Melanoma
- Trial name
- NCT01433302
- Testing
- Punch Biopsy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- M.D. Anderson Cancer Center
Vaginal Stricture
Newly Designed Vaginal Stent to Improve Patient Comfort and Healing Following Vaginal Surgery or Vaginal Radiation
Each year, females need surgery to create a vaginal canal or pelvic radiation to treat cancer. The result is often a narrowing or scarring of their vagina. To aid in healing a stent is often placed.
- Trial name
- NCT04807387
- Testing
- Vaginal Stent A, Vaginal Stent B, Vaginal Stent
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Infertility Female
The Effect of Metformin on Fecundability in an ART(Assisted Reproductive Technology) Setting - the Correlation to Uterine Flows
The basis for obesity's impact on reproduction is not well characterised and there is a controversy whether the key organ influenced by it are the ovaries or the uterus.
- Trial name
- NCT02848950
- Testing
- Metformin
- Volunteers
- 100 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Infertility, Emotional Disorder
Online Prevention of Emotional Disorders in Women Undergoing Fertility Treatments
The main aim of this pilot study is to study the clinical utility and acceptability of a transdiagnostic psychological intervention, the Unified Protocol, delivered in online format to prevent the onset of emotional disorders in…
- Conditions
- Infertility, Emotional Disorder, Anxiety Depression
- Trial name
- RE-FER moodle (NCT06420674)
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Jorge Javier Osma López
Urinary Incontinence
Urinary Incontinence: Reproductive/Hormonal Risk Factors
This study is a continuation or follow-up of two previous studies (RRISK and RRISK2) conducted at the Kaiser Division of Research.
- Trial name
- RRISK3 (NCT00836979)
- Where
- United States
- Volunteers
- 2,161 people
- Sponsor
- Kaiser Permanente
Substance-Related Disorders, Sexually Transmitted Diseases
Adolescent Drug and HIV Prevention in South Africa
The purpose of this trial is to test the effectiveness of a classroom-based prevention program (HealthWise: Learning Life Skills for Young Adults) to reduce the risk of HIV/AIDS and STIs, as well as substance use, among…
- Trial name
- NCT00336180
- Testing
- HealthWise South Africa curriculum
- Where
- South Africa
- Volunteers
- 7,695 people, healthy volunteers welcome
- Sponsor
- Penn State University
Neural Tube Defects, Folic Acid Deficiency
Salt-FA to Increase Folate Levels
Question: How effective is folic acid-fortified iodized salt in increasing serum folate concentrations among non-pregnant and non-lactating women of reproductive age? Hypothesis: Folic acid-fortified iodized salt can increase…
- Conditions
- Neural Tube Defects, Folic Acid Deficiency, Spina Bifida, Anencephaly-Spina Bifida
- Trial name
- NCT06174883
- Testing
- Folic acid fortified iodized salt
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hydrocephalus and Neuroscience Institute
Maternal Death
Maternal Health Service Utilization Among Women of Reproductive Age in Sidama Region, Ethiopia
Introduction: Maternal health service (MHS) utilization helps to decrease maternal morbidity and mortality. However, the existing evidence is not sufficient to design effective and efficient strategies.
- Trial name
- MHSU (NCT05865873)
- Testing
- Health education
- Where
- Ethiopia
- Volunteers
- 1,126 people, healthy volunteers welcome
- Sponsor
- Hawassa University