Clinical trials: Reproduction Dysfunction
Sexual Dysfunction Female
Adipose Tissue-derived Mesenchymal Stem Cell (AD-MSC) Therapy for the Treatment of Sexual Function Impairment in Female
Hormones are a chemical substance synthesized and secreted by endocrine gland. Several vital hormones, including Mullerian hormone (AMH), follicle-stimulating hormone (FSH), and Estradiol (E2), play crucial roles in regulating…
- Trial name
- NCT05329662
- Testing
- Autologous adipose-derived mesenchymal stem cell administration for female with sexual functional deficiency
- Where
- Vietnam
- Volunteers
- 130 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Breast Cancer, Psychosocial Effects of Cancer and Its Treatment
Assessing Women's Attitudes About the Risk of Infertility Related to Adjuvant Therapy for Early Breast Cancer
RATIONALE: Adjuvant therapy given after surgery for early breast cancer may cause infertility. Assessing young women's attitudes and feelings about the risk of infertility may help improve the ability to plan effective treatment.
- Conditions
- Breast Cancer, Psychosocial Effects of Cancer and Its Treatment, Sexual Dysfunction and Infertility, Sexuality and Reproductive Issues
- Trial name
- NCT00062400
- Testing
- psychosocial assessment and care
- Where
- 27 sites in Belgium, Chile and 13 more
- Volunteers
- 385 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Pregnancy, Pelvic Floor Dysfunction
Female Reproductive Health in Canadian Armed Forces
This is a mixed-method study aimed at gathering new evidence on reproductive health among female service members in the Canadian Armed Forces (CAF).
- Conditions
- Pregnancy, Pelvic Floor Dysfunction, Military Personnel, Contraception
- Trial name
- BEARH2025 (NCT07524764)
- Where
- Canada
- Volunteers
- 1,121 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Erectile Dysfunction
Assess the Effect of Daily Treatment of Vardenafil 20mg or Sildenafil 100mg and Placebo on Sperm Function
Assess the effect of daily treatment of vardenafil 20mg or sildenafil 100mg and placebo on sperm function
- Trial name
- NCT00655590
- Testing
- Levitra (Vardenafil, BAY38-9456), Sildenafil
- Where
- 18 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bayer
Anxiety, Cancer Survivor
Mindfulness Intervention in Reducing Anxiety in Patients Who Have Been Treated for Gynecologic Cancer
This pilot clinical trial studies how well a mindfulness-based stress reduction (MBSR) intervention works in reducing anxiety in patients who have undergone treatment for gynecologic cancer but no longer have any sign of disease.
- Conditions
- Anxiety, Cancer Survivor, Cognitive Impairment, Depression
- Trial name
- NCT02518308
- Testing
- Mindfulness-Based Stress Reduction
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Wisconsin, Madison
Obesity, Infertility
Estrogen Sensitivity and Ovulatory Dysfunction in Obesity
The sole purpose of this study is to evaluate pathophysiology of disease. The disease state that is being evaluated is the obesity-related alterations in reproductive hormones The obesity epidemic in the United States is…
- Trial name
- NCT01381016
- Testing
- Estradiol, Gonadotropin-releasing hormone (GnRH), Progesterone
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sexual Dysfunction, Sexuality and Reproductive Issues
L-Arginine Supplements in Treating Women Who Are Cancer Survivors
RATIONALE: L-arginine supplements may improve the quality of life and sexual function in women who are cancer survivors. PURPOSE: This randomized clinical trial is studying an L-arginine supplement to see how well it works…
- Conditions
- Sexual Dysfunction, Sexuality and Reproductive Issues, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00459134
- Testing
- ArginMax
- Where
- 25 sites in United States
- Volunteers
- 186 people
- Sponsor
- Wake Forest University Health Sciences
Asherman Syndrome
Pre-clinical Endometrial Tissular Renovation Study
The endometrium is a tissue with high capacity of renewal ("self-renewal"). This process is regulated by stem cells. Recent studies have shown that bone marrow-derived stem cells (BMDSCs) contribute to tissues and organs…
- Trial name
- PreENTIRE (NCT03665649)
- Testing
- CD133+ cells isolation
- Where
- Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Igenomix
Cervical Mucus Dysfunction, Infertility, Female
Identification of Biomarkers in Cervical Mucus
Cervical mucus is a biological fluid secreted by the endocervical glandular epithelium whose quantitative and qualitative characteristics vary in response to the hormonal stimulus produced by the ovary during the woman's…
- Trial name
- IBISCUS (NCT06771401)
- Testing
- cervical mucus sampling
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Polycystic Ovary Syndrome (PCOS), Obesity & Overweight
A Clincial Study Testing Tirzepatide on Reproductive Function and Metabolic Health in Women With PCOS Who Are Overweight or Obese
This clinical study examines whether tirzepatide can improve ovarian dysfunction in premenopausal women with polycystic ovary syndrome (PCOS) who are overweight or have obesity.
- Trial name
- PERIODS (NCT07326111)
- Testing
- Tirzepatide as an adjunct to lifestyle intervention
- Where
- 2 sites in Germany
- Volunteers
- 198 people
- Sponsor
- University of Bonn
Polycystic Ovarian Syndrome (PCOS), Reproductive Health
Management of Polycystic Ovarian Syndrome-associated Reproductive Dysfunction Through Kefir Supplementation
Polycystic ovary syndrome (PCOS) affect around 6-12% of women of age 18-25 years. Kefir contains bioactive compounds such as lactic acid bacteria, yeast, peptides, polysaccharides and organic acids and acts as a good probiotic…
- Trial name
- NCT07711782
- Testing
- (C0) Control group, (G1) Experimental group
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Lahore
Lead Poisoning, Infertility
Lead, Endocrine Disruption and Reproductive Outcomes
This prospective cohort study of 400 lead exposed and 400 non-lead exposed women and their husbands assesses endocrine dysfunction and adverse reproductive outcomes.
- Trial name
- NCT00023101
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Polycystic Ovary Syndrome, Overweight and Obesity
Research of Exenatide for Overweight/Obese PCOS Patients With IGR
Compare the therapeutic effects of exenatide, metformin and their combination for 3 months on reproductive and metabolic improvements of overweight/obese PCOS patients with impaired glucose regulation.
- Conditions
- Polycystic Ovary Syndrome, Overweight and Obesity, Disorder of Glucose Regulation
- Trial name
- NCT03352869
- Testing
- Exenatide, Metformin
- Where
- China
- Volunteers
- 183 people
- Sponsor
- RenJi Hospital
Fertility Disorders, Thyroid Dysfunction
The Influence of Different Thyroid Autoantibodies on Thyroid Function and Pregnancy Outcome After Assisted Reproductive Technology
The influence of thyroid autoantibodies on thyroid function in pregnancy after fertility treatment is not well known. The objectives of the present study are: 1.
- Trial name
- TgAB (NCT04019509)
- Testing
- blood test, follow up treatment outcome
- Where
- Belgium
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility
Vascular Dysfunction in Offspring of Assisted Reproduction Technologies
The prevalence of infertility has been estimated at 9% worldwide. The steadily increasing use of assisted reproductive technologies (ART) has allowed millions of infertile couples to have children.
- Trial name
- NCT00837642
- Testing
- Transthoracic echocardiography
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Cancer Survivor, Sexual Dysfunction
Low-Dose Testosterone in Improving Libido in Postmenopausal Female Cancer Survivors
RATIONALE: The hormone testosterone may improve the libido (sex drive) in women. It is not yet known whether testosterone is effective in improving libido in female cancer survivors.
- Conditions
- Cancer Survivor, Sexual Dysfunction, Sexuality and Reproductive Issues, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00075855
- Testing
- therapeutic testosterone
- Where
- 16 sites in United States
- Volunteers
- 150 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment
Communication and Intimacy-Enhancing Therapy for Men With Early Stage Prostate Cancer and Their Partners
RATIONALE: Participating in a therapy program may enhance communication and intimacy between men with prostate cancer and their partners.
- Conditions
- Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment, Sexual Dysfunction and Infertility, Sexuality and Reproductive Issues
- Trial name
- NCT00503646
- Testing
- communication intervention, counseling intervention, questionnaire administration
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hormonal Contraception
Quality of Life During Different Regimens of Combined Hormonal Contraceptives in Women of Reproductive Age
The aim of the present study is to investigate the psychosexual effects of combined hormonal contraception regimens, comparing them in terms of estrogen type and dosage, hormonal combination regimen and different routes of…
- Trial name
- NCT06918873
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Sexual Dysfunction Male
Umbilical Cord-Derived Mesenchymal Stem Cell (VCELL 1) for Male Patients With Sexual Deficiency
Sexual functional deficiency affects largely the physical conditions, life and sexual quality of the patients. Hypogonadism affects about 4 to 5 million men in the US, and the incidence increases with age.
- Trial name
- NCT05345418
- Testing
- Umbilical Cord-Derived Mesenchymal Stem Cell for Male Patients with Sexual Deficiency
- Where
- Vietnam
- Volunteers
- 158 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Fertility Disorders, Hypothalamic Dysfunction
Reproductive Hormones During Sustained Administration of Kisspeptin
We want to find out what happens to reproductive hormone levels; Luteinising Hormone (LH), Follicle Stimulating Hormone (FSH), testosterone and oestradiol when kisspeptin is administered to people for a period of 8 days each…
- Trial name
- KisspeptPump (NCT02081924)
- Testing
- Kisspeptin 0.1, Saline, Kisspeptin 0.3
- Where
- United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Imperial College London