Clinical trials: Reproductive Age
BRCA1 and/or BRCA2 Variant Carriers, Fertility
Study on Fertility Parameters in Women With Germline Variants in BRCA1 and BRCA2
Pathogenic variants (PVs) in the BRCA1 and BRCA2 genes are associated with an increased risk of developing breast and ovarian cancers.
- Conditions
- BRCA1 and/or BRCA2 Variant Carriers, Fertility, Reproductive Age, Menopause
- Trial name
- BFert (NCT06710015)
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Menstrual Disorder, Premature Ovarian Failure
The Effect of HPV Vaccine on Menstrual Cycle in Women of Reproductive Age
Cervical cancer is one of the most common cancer in women, making it the fourth largest cause of female cancer mortality worldwide.
- Trial name
- NCT05838157
- Testing
- prophylactic HPV vaccine(bivalent HPV、quadrivalent HPV、9-valent HPV)
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
IVF
Ubiquinone vs. Ubiquinol Supplementation
The objective of this study is to determine if ubiquinol will result in improved reproductive outcomes in older women at a reduced oral dose compared to current standard treatment with ubiquinone.
- Trial name
- NCT06555575
- Testing
- Ubiquinone 200 Mg Oral Capsule, Ubiquinol 100 MG Oral Capsule
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trio Fertility
Child Rearing, Reproductive Behavior
Age 12 Follow-up of Early Preventive Intervention (Memphis)
To examine the impact of prenatal and infancy home visiting by nurses from child age 2 through 12.
- Conditions
- Child Rearing, Reproductive Behavior, Risk Reduction Behavior
- Trial name
- MemphisY12 (NCT00438165)
- Testing
- home visitation
- Where
- United States
- Volunteers
- 609 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Uterine Fibroids Affecting Pregnancy
Composition for Treating Uterine Fibroid (SB-UF)
Pregnenolone \& Pyridoxal Phosphate SB-UF for treating uterine fibroids in women's pregnancies to lose the size of fibroids and to dissolve fibroids.
- Trial name
- SB-UF (NCT04762316)
- Testing
- SB-UF
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- Trieu, Nguyen Thi, M.D.
Infertility, Ovulation Induction
A Clinical Trial to Determine the Effect of Lutropin Alfa on Embryo Quality and Implantation Rate in Advanced Reproductive Age
This is a multicentric, open, randomized, comparative trial aimed to assess the influence of recombinant luteinizing hormone (r-LH) supplementation during controlled ovarian stimulation (COS) in advanced reproductive age in terms…
- Trial name
- NCT01075815
- Testing
- Recombinant human luteinizing hormone (rhLH), Recombinant follicle-stimulating hormone (rFSH)
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Iodine Deficiency
Climat Impact on Urinary Iodine Concentration
Urinary iodine concentration (UIC) is the recommended biomarker of iodine status in populations. Yet, the influence of climate on UIC remains unclear.
- Trial name
- LION (NCT03215680)
- Testing
- Climate
- Where
- 2 sites in South Africa, Tanzania
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Contraceptive Device; Complications
The Contraceptive Efficacy and Safety of an Intravaginal Acetic Acid Thermoreversible Gel on Chinese Women.
The study aims to explore the efficacy and safety of an intravaginal acetic acid thermoreversible gel in Chinese women of reproductive age, comparing it with nonoxinol gel by assessing the six-month Pearl Index and the incidence…
- Trial name
- contraception (NCT06203080)
- Testing
- ancetate gel, nonoxinol gel
- Where
- 4 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Research Institute for Family Planning, China
Nutrient Deficiency
Study of Multiply-fortified Salt Among Women of Reproductive Age and Preschool Children in India
Micronutrient (MN) deficiencies are highly prevalent in India, particularly among women of reproductive age (WRA) and preschool aged children (PSC).
- Trial name
- MFS (NCT05166980)
- Testing
- Mutiply-fortified salt, Iodized salt
- Where
- India
- Volunteers
- 1,389 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Infertility, Fertility
A Trial to Compare the Efficacy and Safety of Ovarian Stimulation With GONAL-f® and Luveris® Starting on Day 1 Versus Day 6 in Women Undergoing Assisted Reproductive Technique
This is a phase IIIb, interventional, multicenter, multinational, randomised, open-label, comparative trial which primary objective is to generate data on the ovarian stimulation profile obtained when Luveris® is started either…
- Conditions
- Infertility, Fertility, Follicle Stimulating Hormone Deficiency
- Trial name
- NCT01497197
- Testing
- GONAL-f®, Luveris®, Recombinant human chorionic gonadotropin (r-hCG)
- Where
- United Arab Emirates
- Volunteers
- 174 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Pain (Visceral, Somatic, or Neuropathic), Women of Reproductive Age
Virtual Menstrual Pain Approaches in Females
This research study is testing two self-care approaches that may help prevent or reduce period pain in young females with recurrent painful menstrual cramps.
- Conditions
- Pain (Visceral, Somatic, or Neuropathic), Women of Reproductive Age, Mental Disorder, Digital Health
- Trial name
- AABQ (NCT07497711)
- Testing
- Virtual Auricular Acupressure, Virtual Baduanjin Qigong Exercise, Self Education
- Where
- Singapore
- Volunteers
- 145 people
- Sponsor
- Nanyang Technological University
Iron Metabolism Disorders
Iron Status in Women of Reproductive Age Reproductive Age
Analyzed iron status, HFE mutations and ethnicity for women in five primary care centers in the United States and Canada using de-identified data from the HEIRS study.
- Trial name
- NCT03276247
- Testing
- observation
- Where
- United States
- Volunteers
- 22,042 people
- Sponsor
- Victor Gordeuk
Polycystic Ovary Syndrome
Effect of Metformin and Probiotics in Reproductive-aged Patients With Polycystic Ovary Syndrome
The purpose of this clinical trial is to evaluate the safety and effectiveness on the clinical and biological parameters of reproductive-aged PCOS women after a 12-week metformin and/or probiotics administration.
- Trial name
- NCT03336840
- Testing
- Metformin tablets, ProMetS probiotics powder, 1. Metformin tablets; 2. ProMetS probiotics powder
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Obesity and Overweight, Anemia, Iron-Deficiency
Different Efficacy of IFA Supplementation Among Obese and Non-obese Women
This clinical trial aims to learn if there is a relationship between OWT/OB and IDA in nonpregnant women of reproductive age and its impact on iron supplementation.
- Trial name
- NCT06622551
- Testing
- Iron-folic acid supplement
- Where
- Indonesia
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Griffith University
Clinical Trial ,Phase I
Drug-drug Interaction Study: Influence of Vilaprisan on Pharmacodynamics (PD) and Pharmacokinetics (PK) of a Combined Oral Contraceptive (COC)
This study will be performed as a multi-center, randomized, double-blind study in 60 healthy women (2 groups of 30 women) to investigate ovarian activity during simultaneous intake of a COC (containing the estrogen EE and the…
- Trial name
- NCT03210246
- Testing
- Vilaprisan (BAY 1002670), Microgynon
- Where
- 2 sites in Germany
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Bayer
Iron-deficiency, Anemia
Iron-Biofortified Rice Intervention in the Philippines
The objective of this randomized efficacy feeding trial was to determine the effects of consuming iron-biofortified rice on iron status in women, compared to non-biofortified rice.
- Trial name
- NCT04623918
- Testing
- Iron-biofortified rice, Control rice
- Where
- Philippines
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Cornell University
Environmental Enteric Dysfunction (EED), Malnutrition
The Maternal EED Study
Undernutrition among women of reproductive age is more common in South Asia than in any other region. In South Asia, the prevalence of maternal undernutrition varies between 10 and 40%.
- Conditions
- Environmental Enteric Dysfunction (EED), Malnutrition, Women of Reproductive Age, Gut Microbiota
- Trial name
- NCT05862363
- Testing
- Microbiota-directed balanced energy protein (MD-BEP), Ready-to-use supplementary food-balanced energy protein (RUSF-BEP), Esophagogastroduodenoscopy (EGD)
- Where
- Bangladesh
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Endometriosis
Study Evaluating ERB-041 in Endometriosis in Reproductive-Age Women
The purpose of this investigational study is to determine if a study medication is safe and effective in reducing the symptoms associated with endometriosis; if the study medication reduces the need for pain medication for…
- Trial name
- NCT00110487
- Testing
- ERB-041
- Where
- 46 sites in United States
- Volunteers
- 200 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Infertility Survey Among Reproductive Age Women With Gynecological and Breast Cancer
This study develops infertility survey among reproductive age women with gynecological and breast cancer. This study aims to learn how women consider whether or not to try to have a baby after surviving cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT04678414
- Testing
- Healthcare Activity, Survey Administration
- Where
- United States
- Volunteers
- 1,410 people
- Sponsor
- M.D. Anderson Cancer Center
Dysmenorrhea, Dyspareunia
Study Evaluating the Safety and Efficacy of ERB-041 on Reduction of Symptoms Associated With Endometriosis in Reproductive-Aged Women
The purpose of the study is to evaluate the efficacy and safety of two doses of ERB-041 (75 mg and 150 mg) relative to placebo on the relief of endometriosis-related symptoms (dysmenorrhea, pelvic pain, and deep dyspareunia) in…
- Conditions
- Dysmenorrhea, Dyspareunia, Endometriosis, Pelvic Pain
- Trial name
- NCT00318500
- Testing
- ERB-041
- Where
- 70 sites in United States, Australia and 5 more
- Volunteers
- 150 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer