Clinical trials: Reproductive Age
Reproductive Age, PCOS (Polycystic Ovary Syndrome)
Functional Proteins in Polycystic Ovary Syndrome
The concentration of functional proteins: kisspeptin, ghrelin, zonulin will be measured and compared in women with polycystic ovary syndrome (PCOS) and insulin resistance (IR), in women with PCOS without IR, and in women without…
- Trial name
- NCT06793098
- Testing
- Measurement of kisspeptin concentration, Measurement of ghrelin concentration, Measurement of zonulin concentration
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Polycystic Ovary Syndrome
Effect of Metformin and Probiotics in Reproductive-aged Patients With Polycystic Ovary Syndrome
The purpose of this clinical trial is to evaluate the safety and effectiveness on the clinical and biological parameters of reproductive-aged PCOS women after a 12-week metformin and/or probiotics administration.
- Trial name
- NCT03336840
- Testing
- Metformin tablets, ProMetS probiotics powder, 1. Metformin tablets; 2. ProMetS probiotics powder
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Iron-deficiency, Anemia
Iron-Biofortified Rice Intervention in the Philippines
The objective of this randomized efficacy feeding trial was to determine the effects of consuming iron-biofortified rice on iron status in women, compared to non-biofortified rice.
- Trial name
- NCT04623918
- Testing
- Iron-biofortified rice, Control rice
- Where
- Philippines
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Cornell University
Women of Reproductive Age, Diabetes Mellitus
Rationale and Design of Diabetes Management With Curcumin and Saffron (DMCS): a Randomised, Three Blind -Blind, Placebo-controlled Study
## Study Hypotheses Summary: Primary Hypothesis: Women with diabetes mellitus receiving the intervention will exhibit significantly lower levels of sugar indicators (FBS, HA1c, 2HPP) and lipid indicators (LDL, HDL, TG) compared…
- Trial name
- NCT06413238
- Volunteers
- 120 people
- Sponsor
- Fateme Moshirenia
Reproductive Age, PCOS (Polycystic Ovary Syndrome)
Pro- and Anti-inflammatory Cytokines in PCOS
The study will involve measurements and comparisons of the concentrations of pro-inflammatory cytokines: IL-6, TNF-α, IL-18, as well as anti-inflammatory cytokine IL-4 in women with polycystic ovary syndrome (PCOS) and insulin…
- Trial name
- NCT06793085
- Testing
- Measurement of interleukin-6 (il-6) concentration in blood serum, Measurement of fasting tumor necrosis factor α (TNF-α) concentration, Measurement of interleukin-18 (il-18) concentration
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Adolescent Behavior, Health Behavior
Exploring Enhanced HFP to Reduce Child Marriage in Bangladesh
Child marriage leads to pregnancy in adolescence, a root cause of both malnutrition and the intergenerational cycle of malnutrition.
- Conditions
- Adolescent Behavior, Health Behavior, Marriage Age
- Trial name
- NCT04758169
- Testing
- Enhanced Homestead Food Production, Control
- Where
- Bangladesh
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Helen Keller International
Infertility, Female, Intracytoplasmic Sperm Injections
Piezo-ICSI to Improve the Developmental Potential of Fertilized Oocytes in Aged Infertility Women With Assisted Reproductive Technology
The goal of this clinical trial is to test Piezo-ICSI on improving oocyte fertilization and embryo development in elderly infertile patients undergoing intracytoplasmic sperm injection (ICSI).
- Trial name
- NCT06459778
- Testing
- Piezo-ICSI
- Where
- China
- Volunteers
- 147 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Serum CNP Levels, Healthy Reproductive Age Women
Serum Levels of C Type Natriuretic Peptide in Different Reproductive Periods
Recent studies have shown that C natriuretic peptide (CNP) is produced from granulosa cells, increasing cumulative guanosine monophosphate (cGMP) production by affecting cumulus cells through natriuretic peptide receptors.It has…
- Conditions
- Serum CNP Levels, Healthy Reproductive Age Women, Healthy Perimenopausal Women, Healthy Postmenopausal Women
- Trial name
- CO (NCT04000815)
- Testing
- C Type Natriüretic Peptide
- Where
- Cyprus
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Adolescents, Anemia
Effect of Micronutrients and Life Skills Education on the Health and Nutrition of Adolescent and Young Women in Pakistan
The primary aims of this study are: 1) To evaluate the impact of supplementation with multiple micronutrients (MMN) from preconception and life skills education among women 15-18.9 years of age at enrolment on the prevalence of…
- Conditions
- Adolescents, Anemia, Pregnancy, Empowerment
- Trial name
- NCT03287882
- Testing
- Multiple micronutrients (UNIMMAP composition), Life skills based education
- Where
- Pakistan
- Volunteers
- 25,447 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Iron-deficiency, Iron Deficiency Anemia
Meals to Improve Absorption of Iron Supplements
One of the targeted objectives of Healthy People 2020 is to reduce iron deficiency among women of reproductive age (WRA). Consuming foods rich in iron and/or oral iron supplementation is typically recommended to improve iron…
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Iron Deficiency Anemia Treatment
- Trial name
- NCT04793906
- Testing
- Iron supplement with a lunch meal containing beef, Iron supplement with a lunch meal containing plant-based alternative
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Uterine Fibroids Affecting Pregnancy
Composition for Treating Uterine Fibroid (SB-UF)
Pregnenolone \& Pyridoxal Phosphate SB-UF for treating uterine fibroids in women's pregnancies to lose the size of fibroids and to dissolve fibroids.
- Trial name
- SB-UF (NCT04762316)
- Testing
- SB-UF
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- Trieu, Nguyen Thi, M.D.
HIV (Human Immunodeficiency Virus)
Evaluation of the Effectiveness of the HPV Education Program Applied to Women
This study aimed to evaluate the effectiveness of an educational program conducted by nurses on Human Papilloma Virus and its effects on women's health in women of reproductive age.
- Trial name
- NCT07468487
- Testing
- Reproductive health education program
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Okan University
Male Infertility, Advanced Paternal Age
Effectiveness of Live Motile Sperm Sorting Device on IVF Outcomes in Advanced Paternal Age
Male infertility contributes significantly to infertility, particularly in advanced paternal age men where sperm DNA fragmentation is increased.
- Conditions
- Male Infertility, Advanced Paternal Age, Assisted Reproductive Technology
- Trial name
- IVF (NCT07605182)
- Testing
- LensHooke® CA0 sperm sorting device, Density Gradient Centrifugation
- Where
- Vietnam
- Volunteers
- 378 people
- Sponsor
- Vietnam Military Medical University
Iron Deficiency
Iron Absorption From Tef-injera in Women of Reproductive Age
Anemia is one of the most common health problems all over the world with around half of preschool-aged children (<5 years) and one third of women affected.
- Trial name
- NCT01687062
- Testing
- FeSO4, reduction of phytate, NaFeEDTA
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
IVF
Ubiquinone vs. Ubiquinol Supplementation
The objective of this study is to determine if ubiquinol will result in improved reproductive outcomes in older women at a reduced oral dose compared to current standard treatment with ubiquinone.
- Trial name
- NCT06555575
- Testing
- Ubiquinone 200 Mg Oral Capsule, Ubiquinol 100 MG Oral Capsule
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trio Fertility
Bariatric Surgery Candidate, Pregnancy
bAriatric sUrgery Registration in wOmen of Reproductive Age
The use of bariatric surgery has risen subsequently over the last decade, especially in women of reproductive age. (Unplanned) pregnancies in this subgroup are not rare because of e.g.
- Trial name
- AURORA (NCT02515214)
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Reproductive Health, Time to Pregnancy
Reproductive Health of Couples of Childbearing Age: a Community Based Prospective Cohort Study
This community based prospective cohort study was established to investigate the fecundability of couples of childbearing age. Data are collected regarding age, body mass index, education, menstrual regularity as well as…
- Conditions
- Reproductive Health, Time to Pregnancy, Infertility, Risk Factor
- Trial name
- ReH-CP (NCT04068428)
- Where
- 4 sites in China
- Volunteers
- 2,313 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Hyperandrogenism
Effects of Androgen Administration on Inflammation in Normal Women
The hypothesis of this study is that DHEA administration to increase male hormone in healthy normal-weight young women to levels present in women with Polycystic Ovary Syndrome will cause an inflammatory response in white blood…
- Trial name
- NCT01753037
- Testing
- Dehydroepiandrosterone (DHEA)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Epilepsy
Counseling on the Interaction of Hormonal Contraceptives and Antiepileptics
Previous studies have shown that women on anti-seizure medications are not informed about the pharmaceutical drug interactions between anti-seizure medications (antiepileptic drugs, AEDs) and certain hormonal contraceptive.
- Trial name
- NCT02485756
- Testing
- Educational handout
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of California, San Diego
Hormonal Contraception
Quality of Life During Different Regimens of Combined Hormonal Contraceptives in Women of Reproductive Age
The aim of the present study is to investigate the psychosexual effects of combined hormonal contraception regimens, comparing them in terms of estrogen type and dosage, hormonal combination regimen and different routes of…
- Trial name
- NCT06918873
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia