Clinical trials: Reproductive Effects
Menopausal Syndrome
Effect of Soya Bean on the Female Reproductive Hormones and Menopausal Symptoms
Menopause is one of the most emotionally, physically and Psychological miserable times in a woman's life.It occurs following cessation of menses resulting in the decline of endogenous estrogen.
- Trial name
- NCT07739615
- Testing
- Soy Bean
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Alex Ekwueme Federal University Teaching Hospital
Sexual and Reproductive Health, Menopausal and Postmenopausal Women
THE EFFECT OF SEXUAL COUNSELING BASED ON THE EXPLISSIT MODEL ON SEXUAL FUNCTION, MARITAL ADJUSTMENT, AND QUALITY OF SEXUAL LIFE IN POSTMENOPAUSAL WOMEN
Sexual health is not merely about sexual dysfunction, but a complex, diverse, and multifaceted natural process encompassing a wide range of aspects of human life, extending from childhood to old age.
- Trial name
- NCT07559916
- Testing
- Group receiving sexual counseling based on the EX PLISSIT model.
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Healthy Volunteers
The Effects of Reproductive Hormones on Mood and Behavior
This study evaluates the effects of estrogen and progesterone on mood, the stress response, and brain function in healthy women.
- Trial name
- NCT00001322
- Testing
- Leuprolide Acetate 3.75, Estradiol, Progesterone
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Fatigue Syndrome, Chronic, Fatigue
Iron Therpay and Fatigue in Women of Reprodcutive Age
For the assessment of anemia and then assessment of fatigue levels in non-anemic women followed by assessment of iron levels and intervention of iron and placebo
- Trial name
- NCT06596161
- Testing
- Iron sucrose
- Where
- Pakistan
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Central Park Medical College
Reproductive Physiological Phenomena
CoQ10 Treatment to Improve Fertility in Elderly Patients
Delaying first childbirth is a progressive trend in the developed societies. Several theories tried to explain the reproductive aging, in purpose to hasten it. One of the theories include mitochondrial dysfunction with aging.
- Trial name
- NCT02010164
- Testing
- Co-enzyme Q10
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
COVID 19
Impact of Cryopreservation Methods on Post-Thaw SARS-CoV-2 in Semen Samples
Cryopreservation of seminal fluid or spermatozoa from epididymary and testicular retrieval represents a crucial tool in managing conditions of permanent or temporary infertility, as well as in cases of secretory and excretory…
- Trial name
- SEM-COV-19 (NCT06703723)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Gingivitis
EFFECT OF SCALING ON SERUM hsCRP LEVELS AND PERIODONTAL PARAMETERS IN SYSTEMICALLY HEALTHY YOUNG WOMEN WITH GINGIVITIS
Gingivitis is a highly prevalent chronic bacterial disease in susceptible children, adults and the elderly, persisting for decades in subjects, and is an essential precursor of periodontitis.
- Trial name
- NCT05639608
- Testing
- SCALING
- Where
- 2 sites in India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
In Vitro Fertilization, Intracytoplasmic Sperm Injection
Effect of GnRH Agonist vs GnRH Antagonist on IVF/ICSI Outcomes.
The aim of this prospective, non-randomised, open-label, clinical trial is to compare the effects of two pituitary suppression regimens; GnRH Agonist-Long Protocol and GnRH Antagonist-Flexible Protocol on clinical and…
- Conditions
- In Vitro Fertilization, Intracytoplasmic Sperm Injection, Infertility
- Trial name
- NCT04724343
- Testing
- Triptorelin acetate, Cetrorelix, recombinant-FSH or recombinant-FSH + human Menopausal Gonadotropin
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Fertilization in Vitro
Ejaculation Abstinence Time and Assisted Reproductive Technology Outcomes
The goal of this clinical trial is to learn if reducing the ejaculation abstinence time can improve the outcome of assisted reproductive technology.
- Trial name
- NCT06410417
- Testing
- Shorten abstinence time
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Health Knowledge, Attitudes, Practice, Training
Evaluating the Effects of Reproductive Health Training on Provider Behavior
The goal of this randomized, controlled, single blinded trial is to evaluate the medium to long-term effects of an Afrocentric sexual health curriculum on health professional students' knowledge, attitudes, and clinical skills in…
- Trial name
- THP-2 (NCT06428058)
- Testing
- Comprehensive sexual health curriculum
- Where
- Tanzania
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Disability Physical
Sexual Function and Quality of Sexual Life in Women With Physical Disabilities
This pilot randomized controlled trial will be carried out with women with physical disabilities registered at a disability center.
- Trial name
- NCT07042646
- Testing
- Sexual and Reproductive Health Training program
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Amasya University
Menopause
Healthy Transitions: Menopause Effect on Obesity, Energy Balance, and Insulin
The purpose of this study is to determine the effect of menopause on obesity, energy balance, and insulin in postmenopausal, obese women.
- Trial name
- NCT00412269
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Adenomyosis, Assisted Reproductive Technology
Low Molecular Weight Heparin on the Adenomyosis Patients'IVF-ET Outcome
In assisted reproductive technology, adenomyosis patients are characterized by lower clinical pregnancy rate, lower implantation rate and higher abortion rate.
- Trial name
- NCT04741295
- Testing
- Low molecular weight heparin
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Nanjing University
Amenorrhea, Dysmenorrhea
Reproductive Effects of Pesticide, PCB and Mercury Exposure in Laotian Immigrants
This project is examining the reproductive effects of exposure to certain compounds that are suspected to act on the endocrine system, e.g. they may act like or interfere with hormones such as estrogen.
- Conditions
- Amenorrhea, Dysmenorrhea, Oligomenorrhea, Anovulation
- Trial name
- NCT00011388
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
PCOS- Polycystic Ovary Syndrome
The Synbiotics Effects in Polycystic Ovary Syndrome: A Randomized Controlled Trial
The goal of this clinical trial is to compare the effect of synbiotics and placebo in Thai women with polycystic ovary syndrome.
- Trial name
- PCOS (NCT06169566)
- Testing
- synbiotics
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maharaj Nakorn Chiang Mai Hospital
Reproductive Health, Abortion
Effects of Prior Induced Termination of Pregnancy on Complications and Pregnancy Outcomes.
A prospective multicenter cohort study to evaluate effects of prior induced termination of pregnancy on complications and pregnancy outcomes.
- Trial name
- NCT04183829
- Testing
- induced termination of pregnancy
- Where
- 12 sites in China
- Volunteers
- 20,000 people
- Sponsor
- National Research Institute for Family Planning, China
Endometriosis, Uterine Fibroids
A Trial of SHR7280 in Healthy Subjects
The study is being conducted to evaluate the effect of high-fat meal on pharmacokinetics of SHR7280 after oral administration and the effect of SHR7280 on QT interval at low and high doses in healthy Chinese volunteers.
- Conditions
- Endometriosis, Uterine Fibroids, Assisted Reproduction
- Trial name
- NCT06969664
- Testing
- SHR7280 Tablet
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Sexual and Reproductive Health, Gynecologic Cancer Survivors
Intelligent Sexual Health Information Support System for Gynecological Cancer Patients
This study aims to develop the LillyBot Smart Sexual Health Consultation System, designed to meet the sexual health learning and consultation needs of gynecological cancer (GC) patients in Taiwan.
- Trial name
- NCT07794098
- Testing
- Intelligent Sexual Health Information Support with Proactive Nurse Researcher Contact, Intelligent Sexual Health Information Support with Safety-Triggered Nurse Researcher Contact, Usual Gynecologic Cancer Care
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Chang Gung Memorial Hospital
Polycystic Ovary Syndrome, Obesity
Effects of GLP-1RAs on Reproductive Outcomes in PCOS and Obesity
The goal of this clinical trial is to examine whether benalutide combined with metformin and healthy lifestyle education in women with PCOS and obesity prior to fertility treatment improves live birth rate and other reproductive…
- Conditions
- Polycystic Ovary Syndrome, Obesity, Infertility, Female
- Trial name
- NCT06775093
- Testing
- GLP-1 receptor agonist, Metformin, healthy lifestyle education
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Peking University Third Hospital
Infertility Female
The Effect of Metformin on Fecundability in an ART(Assisted Reproductive Technology) Setting - the Correlation to Uterine Flows
The basis for obesity's impact on reproduction is not well characterised and there is a controversy whether the key organ influenced by it are the ovaries or the uterus.
- Trial name
- NCT02848950
- Testing
- Metformin
- Volunteers
- 100 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya