Clinical trials: Resection
Lung Neoplasms, Thoracoscopic Lung Resection
Patient-Specific 3D Model-Assisted Preoperative Consultation for Thoracoscopic Lung Resection
This study is a single-center, cluster randomized controlled trial evaluating whether lung three-dimensional model-assisted preoperative consultation can improve shared decision-making in adult patients undergoing thoracoscopic…
- Conditions
- Lung Neoplasms, Thoracoscopic Lung Resection, Shared Decision Making, Preoperative Counseling
- Trial name
- NCT07686549
- Testing
- Lung three-dimensional model and reconstruction-assisted preoperative consultation, Usual preoperative consultation
- Volunteers
- 132 people
- Sponsor
- Tongji Hospital
Lung Neoplasm, Lung Cancer
Lung Ultrasound to Assess Aeration Loss After Lung Resection Surgery
The purpose of this prospective observational study is to assess perioperative changes in lung aeration after lung resection surgery using lung ultrasound, and to explore their relationship with oxygenation, inflammatory…
- Conditions
- Lung Neoplasm, Lung Cancer, Lung Resection Surgery, Thoracic Surgery
- Trial name
- THORUS (NCT04677309)
- Testing
- Perioperative lung ultrasound assessment
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Ana Broseta Lleó
Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection
Pre-incisional Infiltration With Ropivacaine Plus Diprospan for Relieving Postoperative Pain After Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is less invasive compared to traditional thoracotomy, but it is still reported that the incidence of acute pain following VATS exceeds 80%.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection, Segmentectomy, Lobectomy
- Trial name
- NCT07626489
- Testing
- Pre-incisional infiltration with ropivacaine plus diprospan
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Tiantan Hospital
Postoperative Pain, Chronic Postsurgical Pain
Perioperative Quantitative Sensory Testing and Incision Pain Mapping in Thoracic Surgery
Postoperative pain remains a common and clinically important burden after thoracic surgery and may progress to chronic postsurgical pain.
- Conditions
- Postoperative Pain, Chronic Postsurgical Pain, Thoracic Surgery, Lung Resection
- Trial name
- NCT07653932
- Testing
- Perioperative QST and incision pain mapping assessment
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Tongji Hospital
Lung Cancer (Diagnosis), Lobectomy
A Study to Explore the Early Subjective Evaluation and Objective Recovery in Lung Cancer Patients Undergoing Sublobar Resection Versus Lobectomy
The trial was designed as a single-center, non-interventional, prospective observational study to explore the role of a multimodal digital device in analyzing subjective and objective recovery in lung cancer patients undergoing…
- Conditions
- Lung Cancer (Diagnosis), Lobectomy, Sublobar Resection
- Trial name
- NCT07288710
- Where
- China
- Volunteers
- 316 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Bladder (Urothelial, Transitional Cell) Cancer Superficial (Non-Invasive), Transurethral Resection of Bladder Tumor
Evaluation of the Role of Early Second Look TURBT in Management of High Risk Non Muscle Invasive Bladder Cancer
The aim is to evaluate the intraoperative, postoperative and pathologic findings of early second look TURBT and the factors affecting these findings to assess the value of early second TURBT in the management of high risk NMIBC.
- Trial name
- NCT07642102
- Testing
- early second look transurethral resection of bladder tumor
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Video-assisted Thoracoscopic Surgery (VATS), Loxoprofen Sodium Patch
The Efficacy and Safety of Loxoprofen Sodium Patch in Relieving Postoperative Pain After Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is less invasive compared to traditional thoracotomy, but it is still reported that the incidence of acute pain following VATS exceeds 80%.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Loxoprofen Sodium Patch, Local Incision, Postoperative Pain
- Trial name
- NCT07591220
- Testing
- Loxoprofen Sodium Patch on the incision site, Loxoprofen Sodium Patch on the contralateral side
- Volunteers
- 156 people
- Sponsor
- Beijing Tiantan Hospital
Low Anterior Resection Syndrome (LARS), Rectal Neoplasm Malignant
Efficacy and Safety of Transcutaneous Posterior Tibial Nerve Stimulation on Fecal Continence in Patients Undergoing Surgery for Rectal Neoplasia
Rectal neoplasia is one of the most prevalent cancers in Spain, and the treatment of choice is total mesorectal excision (TME), as it has demonstrated significant oncological improvements.
- Conditions
- Low Anterior Resection Syndrome (LARS), Rectal Neoplasm Malignant, Quality of Life (QOL), Fecal Incontinence (FI)
- Trial name
- NCT07632196
- Testing
- Posterior tibial nerve stimulation intervention group, Control group
- Where
- 2 sites in Spain
- Volunteers
- 84 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Crohn Disease (CD), Ileocolic Resection
Evaluation of Therapeutic Strategy to Prevent Crohn's Disease Endoscopic poSToperatIve recurreNce Based on earlY Dosage of Faecal Calprotectin
Crohn's disease (CD) (> 200,000 patients in France) is a chronic inflammatory disease that can lead to progression of intestinal destruction and impaired quality of life.
- Conditions
- Crohn Disease (CD), Ileocolic Resection, Post-endoscopic Operative Reccurence
- Trial name
- DESTINY II (NCT06972901)
- Testing
- Early faecal calprotectin dosage
- Where
- 8 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Clermont-Ferrand
Low Anterior Resection Syndrome, Rectal Cancer
Transanal Irrigation for the Management of LARS
This study aims to evaluate the impact of Transanal irrigation (TAI) on the quality of life and low anterior resection symptoms (LARS) in Canadian rectal cancer survivors living with minor to major LARS.
- Trial name
- TAI-LARS (NCT05007015)
- Testing
- Transanal Irrigation
- Where
- 8 sites in Canada
- Volunteers
- 66 people
- Sponsor
- Jewish General Hospital
Intestinal Diseases, Intestinal Resection
Implementation of a Pediatric ERAS-based Protocol in Intestinal Resection With Primary Anastomosis
Enhanced Recovery After Surgery (ERAS) is a multimodal perioperative care strategy designed to reduce surgical stress, decrease postoperative complications, and accelerate recovery after surgery.
- Trial name
- PeERAS (NCT07504549)
- Testing
- Standardized Pediatric ERAS-Based Perioperative Protocol
- Where
- 9 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Michał Pasierbek
Esophagectomy, Pulmonary Wedge Resection
A Retrospective Analysis of Statin Use and Outcome After Thoracic Cancer Surgery
There is data to support an association between impaired preoperative endothelial function and adverse postoperative outcome. This study will investigate the potential association between perioperative statin use and improved…
- Conditions
- Esophagectomy, Pulmonary Wedge Resection, Pulmonary Lobectomy, Pulmonary Pneumonectomy
- Trial name
- NCT01169051
- Volunteers
- 569 people
- Sponsor
- Vanderbilt University Medical Center
Detrusor Underactivity, Transurethral Resection of the Prostate (TURP)
The Effect of Detrusor Underactivity in Determining Outcomes After Transurethral Resection of the Prostate for Treatment of Benign Prostatic Hyperplasia
The aim of this clinical trial is to evaluate the effect of detrusor underactivity on the functional and symptomatic outcomes following transurethral resection of the prostate (TURP) in benign prostatic hyperplasia patients…
- Trial name
- NCT07596537
- Testing
- transurethral resection of Prostate
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Bladder (Urothelial, Transitional Cell) Cancer, Bladder Cancer Recurrence
Association Between Irrigation Fluid Absorption and Perioperative cfDNA Dynamics After TURBT
This prospective observational cohort study aims to evaluate the association between intraoperative irrigation fluid absorption and perioperative cell-free DNA (cfDNA) dynamics in patients undergoing transurethral resection of…
- Conditions
- Bladder (Urothelial, Transitional Cell) Cancer, Bladder Cancer Recurrence, Progression of Bladder Cancer, Transurethral Resection of Bladder Tumor
- Trial name
- NCT07589413
- Testing
- Measurement of Intraoperative Irrigation Fluid Absorption and Perioperative cfDNA Profiling
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Zhiping Wang
Hepatocellular Carcinoma (HCC), Downstaging
Radiomics Subtyping to Guide Surgery vs. Maintenance Therapy After HCC Downstaging
The goal of this observational study is to learn about the long-term treatment outcomes for patients with initially unresectable hepatocellular carcinoma (HCC) who achieve successful downstaging with the combination therapy of…
- Conditions
- Hepatocellular Carcinoma (HCC), Downstaging, Liver Resection, Lenvatinib
- Trial name
- NCT07581769
- Testing
- Liver resection, TACE plus Lenvatinib and PD1 inhibiter
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Low Anterior Resection Syndrome
Paula Method of Exercises in Patients With LARS Syndrome:Randomized Controlled Trial
Sphincter sparing rectal resection surgery, either total mesorectal excision (TME) with a temporary loop ileostomy or partial mesorectal excision (PME), is the mainstay of rectal cancer treatment , however, these treatments are…
- Trial name
- NCT05682157
- Testing
- Paula Method of muscle exercises
- Where
- 2 sites in Israel
- Volunteers
- 62 people
- Sponsor
- Hadassah Medical Organization
Low Anterior Resection Syndrome, Quality of Life (QOL)
Bowel Dysfunction After Low Rectal Resection. An Pilot Study Using Psyllium Husk In Rectal Cancer Patients.
Rectal cancer constitutes 1/3 of more than 4500 annually diagnosed cases of colorectal (CRC) in Norway. With the advances in radiochemotherapy, and surgical techniques, the long-term survival rate is increasing after surgery…
- Trial name
- NCT06724198
- Testing
- Psyllium husk
- Where
- Norway
- Volunteers
- 24 people
- Sponsor
- Sykehuset Telemark
Rectal Cancer, Total Neoadjuvant Treatment
Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.
This study hypothesizes that approximately 50% of rectal cancer patients can preserve their rectum using a watch-and-wait strategy if they achieve a complete or near-complete clinical response to total neoadjuvant therapy (TNT).
- Conditions
- Rectal Cancer, Total Neoadjuvant Treatment, Neoadjuvant Therapy, Radiotherapy
- Trial name
- NCT06758830
- Testing
- Radiation Therapy, Chemoradiotherapy, Consolidation Chemotherapy
- Where
- Lithuania
- Volunteers
- 400 people
- Sponsor
- National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos
Rectal Cancer, Low Anterior Resection Syndrome
The Effects of Kegel Exercise Combined With Biofeedback Therapy on Bowel Function Recovery, Emotional Distress, and Quality of Life in Patients Following Low Anterior Resection for Rectal Cancer
This randomized controlled trial aims to evaluate the effects of combining Kegel exercise with a single biofeedback session on bowel function, emotional distress, and quality of life in patients who have undergone low anterior…
- Conditions
- Rectal Cancer, Low Anterior Resection Syndrome, LARS - Low Anterior Resection Syndrome
- Trial name
- BFT in LARS (NCT07253298)
- Testing
- Kegel Exercise with Biofeedback, Kegel Exercise Only
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- National Taiwan University Hospital
Hepatic Tumor Resection
Anesthesia on Gut Microbiota and Metabolomics
Hepatectomies are performed for the treatment of hepatic tumors and livingdonor liver transplantation. The success of liver resection relies on the remnant liver's ability to regenerate after major tissue loss.
- Trial name
- NCT04767503
- Testing
- Propofol, Desflurane
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital