Clinical trials: Residual
Lymphoma
Monoclonal Antibodies in Detecting Residual Disease in Patients Who Have Been Treated for Non-Hodgkin's Lymphoma
RATIONALE: Diagnostic imaging procedures, such as radiolabeled monoclonal antibodies, may improve the ability to detect the residual disease in patients who have been treated for non-Hodgkin's lymphoma.
- Trial name
- NCT00003338
- Testing
- immunoscintigraphy, technetium Tc 99m epratuzumab
- Where
- 8 sites in United States, Austria and 3 more
- Volunteers
- 60 people
- Sponsor
- Gilead Sciences
Residual Gastric Contents, Pulmonary Aspiration of Gastric Contents
Effect of Fasting Recommendations Among Patients Using GLP-1 Receptor Agonists
The aim of this randomised controlled trial is to determine the effect of a 24-hour clear liquid diet compared to standard fasting guidelines on the proportion of participants who present with increased residual gastric contents…
- Trial name
- NCT06839248
- Testing
- 24-hour clear liquid diet, Standard fasting guidelines
- Where
- 2 sites in Australia
- Volunteers
- 154 people
- Sponsor
- St Vincent's Hospital Melbourne
Long Distance Running
Immediate, Residual, and Cumulative Effects of Fartlek, Hill Circuit, and Roll-On Training in Long-Distance Runners
This randomized controlled trial will compare Fartlek, hill circuit, and roll-on training in well-trained long-distance runners.
- Trial name
- IRCT-LDR (NCT07784140)
- Testing
- Fartlek training, Hill Circuit, Roll-On
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Debre Markos University
Relapsed / Refractory Multiple Myeloma
Comparing Lower Versus Standard Doses of Belantamab Mafodotin With Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma.
This study is testing whether a lower dose of belantamab mafodotin used together with pomalidomide and dexamethasone can provide similar effectiveness with fewer side effects compared with the standard dose in patients with…
- Trial name
- REBEL (NCT07748689)
- Testing
- Belantamab Mafodotin, Pomalidomide, Dexamethasone
- Volunteers
- 228 people
- Sponsor
- Polish Myeloma Consortium
IgG4-Related Diseases
A Study on the Effect of MRD Detected by FAPI PET / CT on the Recurrence of IgG4-RD
This study intends to use the new technology of fibroblast activation protein PET / CT to study whether the tiny residual lesions detected by 68Ga-FAPI PET / CT are related to the recurrence of IgG4-RD in patients with IgG4-RD…
- Trial name
- NCT07104058
- Testing
- 68Ga-FAPI PET / CT
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Luo Yaping
Peritoneal Dialysis
Study to Evaluate the Protective Effect of α-Keto Acid With Low-protein Diet on Renal Function in PD Patients
This randomized, open-label, prospective study will evaluate the renal effective effect of compound α-Keto Acid plus low protein diet in PD Patients.
- Trial name
- NCT00734552
- Testing
- α-Keto Acid with low protein diet, Normal protein diet
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Glioma, Malignant
Nimotuzumab Combined With the Stupp Regimen for Postoperative Residual Glioblastoma
This is a prospective, single-arm study. The study population consists of adult patients with a confirmed diagnosis of EGFR-positive high-grade glioma who have radiographic residual tumor following surgical resection.
- Trial name
- Nimotuzumab (NCT07707973)
- Testing
- nimotuzumab, Temozolomide, Radiotherapy
- Volunteers
- 50 people
- Sponsor
- Tianjin First Central Hospital
Multiple Myeloma
Risk Stratification and MRD-driven Maintenance for MM After ASCT
This study evaluates the maintenance strategy based on risk stratification and MRD status after stem cell transplantation. This is a single-arm, multicenter, prospective study.
- Trial name
- NCT06697483
- Testing
- Daratumumab, Lenalidomide
- Where
- 4 sites in China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Breast Cancer
A PoC Study to Evaluate Treatments' Efficacy by Monitoring MRD Using ctDNA in HR-positive/HER2-negative EBC Population
This trial is a multicenter, open-label, non-comparative, phase II, biomarker-driven adjuvant treatment study involving the periodic collection and analysis of blood samples from patients with HR-positive/HER2-negative…
- Trial name
- MiRaDoR (NCT05708235)
- Testing
- Giredestrant, Abemaciclib, Inavolisib
- Where
- 41 sites in Spain, United Kingdom
- Volunteers
- 976 people
- Sponsor
- MedSIR
Multiple Myeloma
Free From Maintenance Drug Therapy in Multiple Myeloma (The FREEDMM Trial) for Minimal Residual Disease (MRD
A pilot study to assess the risk of progression after stopping post-autologous stem cell transplant (ASCT) maintenance therapy in Minimal Residual Disease (MRD)-negative MM patients.
- Trial name
- HEME-20 (NCT05192122)
- Testing
- Discontinue maintenance therapy SOC
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois Chicago
Acute Myeloid Leukemia, Adult
Midostaurin in MRD (Minimal Residual Disease) Positive Acute Myeloid Leukemia After Allogeneic Stem Cell Transplantation
The MAURITIUS trial is a single-arm, multicenter phase II study of single treatment with midostaurin being applied to AML (acute myeloid leukemia) patients with activating FLT3 (FMS-like tyrosine kinase3) mutations and either…
- Trial name
- NCT03951961
- Testing
- Midostaurin
- Where
- 4 sites in Germany
- Volunteers
- 1 people
- Sponsor
- University of Jena
Carcinoma, Basal Cell, Intraoperative BCC Detection by Fast Raman Device
Intraoperative Detection of Residual BCC by Fast Raman
The main objective of this research is to develop a new scanning technology called the Fast Raman device, to accurately check the skin removed by the surgeon and detect any residual cancer cells; if found, additional skin can…
- Trial name
- NCT03482622
- Testing
- Fast Raman
- Volunteers
- 600 people
- Sponsor
- University of Nottingham
Insomnia, Depression
Acupuncture for Residual Insomnia Associated With Major Depressive Disorder
The purpose of this study is to evaluate the clinical effectiveness of acupuncture treatment on residual insomnia in major depressive patients.
- Trial name
- NCT00838994
- Testing
- Acupuncture
- Where
- Hong Kong
- Volunteers
- 78 people
- Sponsor
- The University of Hong Kong
Non-Small Cell Lung Cancer
A Study Comparing Sotorasib With Durvalumab in People With Non-Small Cell Lung Cancer (NSCLC)
In this study, the researchers will look at whether having participants switch from durvalumab to sotorasib when they have detectable minimal residual disease (MRD) is an effective treatment approach for locally advanced…
- Trial name
- NCT06333678
- Testing
- Durvalumab, Sotorasib
- Where
- 10 sites in United States
- Volunteers
- 10 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Sleep, Neurobehavioral Manifestations
Hangover, Congeners, Sleep and Occupational Performance
The objective is to investigate residual effects of heavy drinking, with or without hangover symptoms. The primary aim is to test several hypotheses about residual effects of heavy drinking.
- Trial name
- NCT00247585
- Testing
- Ethanol (Bourbon or Vodka)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Major Depressive Disorder
Stress Management in Depressive Disorder: Resilience Training vs. Yoga: Biological, Epigenetic, and Brain Correlates
The aim of this clinical trial is to evaluate the effects of a Resilience and Stress Management Intervention Program (RASMUS) compared with yoga on stress perception, coping strategies, depressive symptoms, anxiety, resilience…
- Trial name
- NCT06229652
- Testing
- RASMUS Resilience Training, Body-oriented Yoga
- Where
- Austria
- Volunteers
- 150 people
- Sponsor
- Medical University Innsbruck
Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia
This phase II trial studies how well cytarabine and idarubicin or daunorubicin with or without pembrolizumab work in treating patients with newly-diagnosed acute myeloid leukemia.
- Conditions
- Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Acute Myeloid Leukemia Post Cytotoxic Therapy, Secondary Acute Myeloid Leukemia
- Trial name
- NCT04214249
- Testing
- Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy
- Where
- 10 sites in United States
- Volunteers
- 49 people
- Sponsor
- National Cancer Institute (NCI)
Stage I Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocytic Leukemia
Ibrutinib in Treating Minimal Residual Disease in Patients With Chronic Lymphocytic Leukemia After Front-Line Therapy
This phase II trial studies the side effects and how well ibrutinib works in treating patients with chronic lymphocytic leukemia who responded to initial treatment used to reduce a cancer (front-line therapy) but have residual…
- Conditions
- Stage I Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocytic Leukemia, Stage III Chronic Lymphocytic Leukemia, Stage IV Chronic Lymphocytic Leukemia
- Trial name
- MERIT (NCT02649387)
- Testing
- Ibrutinib, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Mayo Clinic
Small-cell Lung Cancer, Residual Tumor
Chemoimmunotherapy Plus Residual Lesion Irradiation for the Treatment of Extensive Stage Small-cell Lung Cancer
This is a phase II trial studies the effect of chemoimmunotherapy sequential residual tumor irradiation in treating patients with extensive stage small cell lung cancer.
- Conditions
- Small-cell Lung Cancer, Residual Tumor, Radiation
- Trial name
- NCT06514118
- Testing
- residual tumor irradiation
- Where
- 3 sites in China
- Volunteers
- 70 people
- Sponsor
- Qingdao Central Hospital
Non Small Cell Lung Cancer
Local Radiotherapy for Residual Tumor Lesions During the First-line Treatment
This study aimed to confirmed that local radiotherapy for residual lesions can significantly prolong the efficacy of chemotherapy combined with immunotherapy in the initial treatment of advanced non-small cell lung cancer.
- Trial name
- NCT05205226
- Where
- China
- Volunteers
- 636 people
- Sponsor
- Hunan Province Tumor Hospital
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