Clinical trials: Resolution
Chronic Plaque Psoriasis
LCD Solution Versus Calcipotriol Cream in the Treatment of Moderate Plaque Psoriasis
The purpose of this study is to compare the safety and effectiveness of a new topical LCD solution and a commercially available calcipotriol (Vitamin D) cream in reducing the symptoms of plaque psoriasis and improving the quality…
- Trial name
- NCT00705900
- Testing
- LCD, calcipotriol
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NeoStrata Company, Inc.
Cardiac Surgical Procedures, Extracorporeal Circulation; Complications
Acute Kidney Injury After Cardiac Surgery
PrimECC is a colloid priming solution for cardiopulmonary bypass/ extracorporeal circulation (ECC) based on Ringers Lactate, supplmeneted with Dextran 40 and Dextran 1.
- Conditions
- Cardiac Surgical Procedures, Extracorporeal Circulation; Complications, Acute Kidney Injury
- Trial name
- NCT04293744
- Testing
- Colloid priming solution for ECC circuit, Standard priming solution for ECC circuit
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- XVIVO Perfusion
Wound Healing Time
Enhanced Early Soft-Tissue Healing With THERAVEX Technology
randomized, double-blind clinical trial aims to evaluate the effect of different postoperative mouthwashes on early soft-tissue healing following tooth extraction
- Trial name
- NCT07580599
- Testing
- THERAVEX Total Oral Care Plus, Chlorhexidine 0.12% (Paroex), Warm saline
- Where
- Lebanon
- Volunteers
- 51 people
- Sponsor
- Biointelligent Technology Systems SL
Pulmonary Disease, Chronic Obstructive
An Efficacy Study of GSK2269557 Added to Standard Care in Subjects With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The purpose of this study is to evaluate the efficacy of GSK2269557 administered in addition to standard of care in adult subjects diagnosed with an acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT02294734
- Testing
- GSK2269557
- Where
- 17 sites in Belgium, Denmark and 3 more
- Volunteers
- 126 people
- Sponsor
- GlaxoSmithKline
Common Cold
Warming Sensation and Tolerability Study of Acetylcysteine 2% Oral Solution for Productive Cough
This is a 1-treatment arm, open label design. This 1-day study includes a screening on day of attendance at clinic, followed by a washout period of 30 minutes to 8 hours (if participants are eligible for dosing the same day).
- Trial name
- NCT02822287
- Testing
- Acetylcystine
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- GlaxoSmithKline
Lennox Gastaut Syndrome, Dravet Syndrome
Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution
This study will monitor for potential chronic liver injury and liver fibrosis, in participants treated with cannabidiol oral solution.
- Conditions
- Lennox Gastaut Syndrome, Dravet Syndrome, Tuberous Sclerosis Complex
- Trial name
- NCT05044819
- Testing
- Cannabidiol
- Where
- 26 sites in United States
- Volunteers
- 154 people
- Sponsor
- Jazz Pharmaceuticals
Healthy
LEO 27847 - Single Dose Bioavailability Study of Oral Solution Versus Tablet in Healthy Subjects
The purpose of this phase 1 study is to determine the relative bioavailability following single oral dose administration of LEO 27847 solution compared to LEO 27847 tablets in healthy male subjects as well as to determine the…
- Trial name
- NCT01143298
- Testing
- LEO 27847 oral solution
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Undergoing Esophagogastroduodenoscopy (EGD)
High Resolution Optical Imaging of the Esophagus Using the Nvision Volumetric Laser Endomicroscopy (VLE™) Imaging System
This is a single center, single arm, open label observational trial of patients undergoing EGD. The primary objective of this clinical trial is to evaluate the ability of physicians to position the NvisionVLE catheter to acquire…
- Trial name
- NCT01844921
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NinePoint Medical
Cystic Fibrosis
Study of Denufosol Inhalation Solution in Patients With Mild to Moderate Cystic Fibrosis Lung Disease
The purpose of this trial is to evaluate the effects of a single dose of denufosol versus placebo on mucociliary clearance in patients with mild to moderate CF lung disease
- Trial name
- NCT00425165
- Testing
- denufosol tetrasodium (INS37217) Inhalation Solution
- Volunteers
- 6 people
- Sponsor
- Merck Sharp & Dohme LLC
Dry Eye Disease
A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101 Ophthalmic Solution, Versus Vehicle Control in the Treatment of Dry Eye Disease in Patients With Autoimmune Disease
A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101 Ophthalmic Solution, versus Vehicle Control in the treatment of Dry Eye Disease in Patients with Autoimmune Disease
- Trial name
- NCT05629364
- Testing
- KIO-101
- Where
- Australia
- Volunteers
- 4 people
- Sponsor
- Kiora Pharmaceuticals, Inc.
COVID19
Study to Evaluate the Safety and Efficacy of VIRAZOLE® in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19_#2
This study is a Phase 1, open label, non-randomized, two-arm interventional clinical trial to evaluate the safety and efficacy of Virazole® in hospitalized adult patients who have tested positive for COVID-19 and, as a result…
- Trial name
- NCT04356677
- Testing
- 50 mg/mL Virazole, 100 mg/mL Virazole
- Sponsor
- Bausch Health Americas, Inc.
Cataract
Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
- Trial name
- NCT00703781
- Testing
- bromfenac ophthalmic solution
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Bausch & Lomb Incorporated
Dehydration
Oral Rehydration Solution and Dehydration Recovery
This is a prospective, randomized, controlled, blinded, crossover, study to evaluate the effects of an oral hydration solution.
- Trial name
- NCT06368765
- Testing
- Oral Rehydration Solution (ORS), Water
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Dry Eye
Study of VVN001 Ophthalmic Solution in Dry Eye Disease
This is a Phase 2a, multi-center, double-masked, randomized, vehicle-controlled, parallel-group study designed to evaluate the safety and tolerability and to explore the efficacy activity of VVN001 ophthalmic solution versus…
- Trial name
- NCT04556838
- Testing
- VVN001 Ophthalmic Solution 1%, VVN001 Ophthalmic Solution 5%, Vehicle
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- VivaVision Biotech, Inc
Procedural Sedation
A Trial of Intranasal Remimazolam Pharmacokinetics, Pharmacodynamics, Safety and Bioavailability
A prospective dose escalation, nine period cross-over trial assessing the safety, pharmacokinetics, bioavailability and pharmacodynamics of escalating doses of Remimazolam when administered intranasally as powder and solution in…
- Trial name
- NCT03329014
- Testing
- Remimazolam
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Paion UK Ltd.
Social Anxiety Disorder
Cannabidiol (CBD) for the Treatment of Social Anxiety Disorder
A phase 2, multicenter, double-blind, parallel group, placebo-controlled, randomized clinical study, designed to compare the efficacy, safety, and tolerability of 2 dose levels of CBD and a matching placebo for the treatment of…
- Trial name
- NCT05600114
- Testing
- Cannabidiol oral solution
- Where
- 17 sites in United States
- Volunteers
- 239 people
- Sponsor
- EmpowerPharm Inc.
Pulmonary Disease, Chronic Obstructive
Efficacy and Safety Comparison of Tiotropium Inhalation Solution (Respimat Inhaler) and Spiriva HandiHaler in COPD
Non-inferiority of lung function response to Tiotropium inhalation solution compared to Spiriva HandiHaler
- Trial name
- NCT00239447
- Testing
- Tiotropium, HandiHaler, Respimat SMI
- Where
- 11 sites in United States, Canada
- Volunteers
- 131 people
- Sponsor
- Boehringer Ingelheim
Healthy
AZD 2066 Single Dose Formulation and Food Effect Study in Healthy Volunteers
A open label two way crossover formulation and food effect study in healthy volunteers to assess the pharmacokinetics of a single dose of AZD2066 new oral solid formulation and an oral solution
- Trial name
- NCT00690404
- Testing
- AZD2066
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
A Study of Mirikizumab Solution (LY3074828) in Healthy Participants
The main purpose of this study is to assess the safety and tolerability of mirikizumab (LY3074828) solution formulation administered as a single injection compared with two injections under the skin in healthy participants.
- Trial name
- NCT07446101
- Testing
- Mirikizumab
- Where
- 5 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Single Chronic Wound, Lower Limb Wound
Telemonitoring of Chronic Wound Patients Using MyDerm, a Digital Solution: Feasibility Study
The aim of this study is to assess the feasibility of integrating myDerm for remote monitoring of chronic wounds into everyday practice, for patients over 18 years of age suffering from a single chronic wound of the lower limb…
- Trial name
- PIXAPROM (NCT06704087)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Pixacare
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