Clinical trials: Resolution
Swallowing Contraction Strength
Investigating the Correlations Between Dysphagia Symptoms and Swallowing Muscle Groups by HRPM-I
Investigating the correlation between the dysphagia symptoms and swallowing muscle groups by high resolution pharyngeal manometry with impedance
- Trial name
- NCT06006195
- Testing
- patients with dysphagia symptoms, patients without dysphagia symptoms
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Colorectal Cancer, Colonoscopy
Fixed Low-dose Simethicone Combined With Macrogol 4000 (PEG) Reduces Colon Bubble Formation in Colonoscopy
Several randomised studies have shown that the addition of low-dose Simethicone to the bowel preparation was sufficient to reduce the presence of bubbles during colonoscopy.
- Conditions
- Colorectal Cancer, Colonoscopy, Bowel Preparation Solution
- Trial name
- XIMEPEG-RL (NCT06319924)
- Testing
- Simethicone combined with Macrogol 4000 (PEG)
- Where
- 5 sites in France
- Volunteers
- 601 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Female Infertility
Recombinant Follicle-stimulating Hormone in Treatment for Infertility
This is a randomized multi-centre, assessor-blind, parallel-group study to be conducted in 250 women in the age group of 20 to 39 years (both inclusive), who are indicated to undergo COS as part of assisted reproductive…
- Trial name
- REFRESH (NCT05266924)
- Testing
- Recombinant Human Follicle Stimulating Hormone 900 IU (66.0 μg) / 1.5mL Solution for Injection in Prefilled Pen
- Where
- India
- Volunteers
- 250 people
- Sponsor
- Bharat Serums and Vaccines Limited
Glaucoma and Ocular Hypertension
A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 4 Study
This is a Phase III, randomized, double-masked, active-controlled, parallel-group, multi-center study. Subjects diagnosed with glaucoma or OHT who meet eligibility criteria at Visit 1 (Screening) will washout of their current…
- Trial name
- NCT03691662
- Testing
- DE-117 Ophthalmic Solution, Timolol Maleate Ophthalmic Solution 0.5%
- Where
- 34 sites in United States
- Volunteers
- 417 people
- Sponsor
- Santen Inc.
Diabetic Macular Edema, Hard Lipid Exudates
The Effect of Intravitreal Ranibizumab on Visual Acuity and Hard Exudate Resolution in the Treatment of Diabetic Macular Edema With Center Involved Edema and Lipid Exudates
This is an open-label, Phase I/II study of intravitreally administered 0.3mg ranibizumab in subjects with diabetic macular edema and lipid exudates in the central subfield.
- Trial name
- NCT02448446
- Testing
- ranibizumab 0.3mg
- Where
- 4 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- South Coast Retina Center; Carson, McBeath, Boswell, Inc.
Skin Lesion, Skin Cancer
Applicability of a Cellular Resolution Full-field OCT Image System for Pigmented and Non-pigmented Skin Tumors
The incidence of skin cancer has been continuously increasing over the past decades und the number of non melanoma skin cancer is well as melanoma is still going to increase.
- Trial name
- NCT05068310
- Testing
- Cellular resolution full-field optical coherence tomography, Confocal microscopy, Optical coherence tomography imaging
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Apollo Medical Optics, Ltd
Coronary Artery Disease
9 Months Extension Study of SOMVC001 Study (GALA) Vascular Conduit Preservation Solution
This is a 9-months extension to the following study, protocol number: 003-03: "A study to evaluate the use of SOMVC001 (GALA) vascular conduit preservation solution in patients undergoing coronary artery bypass grafting (GABG)".
- Trial name
- NCT02774824
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- Perrault Louis P.
Hydrocortisone, Depression
Exploring the Effects of Corticosteroids on the Human Hippocampus
Chronic corticosteroid (CS) exposure is associated with changes in memory and the hippocampus in both humans and in animal models.
- Conditions
- Hydrocortisone, Depression, Healthy Volunteers
- Trial name
- NCT03896659
- Testing
- Hydrocortisone Oral
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Keratoconjunctivitis Sicca, Dry Eye
Tavilermide Ophthalmic Solution for the Treatment of Dry Eye
The purpose of this study is to assess the safety and efficacy of 5% tavilermide and 1% tavilermide ophthalmic solutions compared with placebo ophthalmic solution in treating the signs and symptoms of dry eye.
- Trial name
- NCT03925727
- Testing
- Tavilermide ophthalmic solution
- Where
- 22 sites in United States
- Volunteers
- 623 people
- Sponsor
- Mimetogen Pharmaceuticals USA, Inc.
Postmenopausal Osteoporosis, Postmenopause
Frequency of Hyperparathyroidism in Postmenopausal Osteoporosis and Its Treatment
Recently, an increase in the prevalence of hyperparathyroidism and hypovitaminosis D in postmenopause women has been occurring in Mexico and the world.
- Conditions
- Postmenopausal Osteoporosis, Postmenopause, Hyperparathyroidism, Secondary, Hypovitaminosis D
- Trial name
- NCT05347082
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 47 people
- Sponsor
- Hospital Regional 1o de Octubre
Obesity
Next Steps: a Community-led Solution to Address Childhood Obesity
The purpose of Next Steps pilot intervention is to develop and test a new program designed to help low-income multiethnic families with overweight or obese children achieve long-term maintenance of healthful behaviors following…
- Trial name
- NCT01912859
- Testing
- Nutrition/physical activity intervention
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cerebral Stroke
Super-Resolution Ultrasound of the Brain in 3D
The goal of this proof of concept study is to determine if the visualization of the middle cerebral artery and its perforators, through 3D transtemporal ultrasound imaging, is possible thanks to an off-line analysis by 3D…
- Trial name
- ESRC3D (NCT06133179)
- Testing
- Transtemporal ultrasound with contrast product (Sonovue)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Contact Lens Solutions
Evaluation of a Multi-Purpose Solution
This study evaluates a multi-purpose solution when used on a daily wear basis by currently adapted soft contact lens wearers.
- Trial name
- NCT00710879
- Testing
- Bausch & Lomb Multi-Purpose Solution
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myocardial Ischemia
Adenosine's Effect on STunning Resolution in Acute Myocardial Infarction
The aim of this study is to evaluate the effect of adenosine on the recovery of myocardial akinesia in ST-elevation myocardial infarction (STEMI).
- Trial name
- A-STAMI (NCT05014061)
- Testing
- Adenosine
- Sponsor
- Vastra Gotaland Region
Chronic Ankle Instability, CAI, Functional Magnetic Resonance Imaging (fMRI)
fMRI Study on Cerebral Localization and Network Mechanisms of rTMS in Chronic Ankle Instability Treatment
Chronic ankle instability (CAI) is a common sports injury that often leads to recurrent injuries and functional deficits. While conventional rehabilitation can restore ankle stability, the underlying neurophysiological mechanisms…
- Trial name
- NCT06971705
- Testing
- repetitive transcranial magnetic stimulation, rTMS, ankle stability training
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Wuhan University
Healthy, Topical Anesthesia
Cryotherapy as a Topical Anesthetic in Healthy Children
In this study, the investigators aimed to compare the effects of topical anesthetic materials and cold application on pain perception.
- Conditions
- Healthy, Topical Anesthesia, Pediatric Dentistry, Cryotherapy
- Trial name
- NCT07198022
- Testing
- Cryotherapy, topical anesthetic, Topical anesthetic gel
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Coronavirus Infection
The Study of "Gam-COVID-Vac" Vaccine Against COVID-19 With the Participation of Volunteers of 60 y.o and Older
The purpose of this study: to assess the safety, tolerability and immunogenicity of the drug "Gam-COVID-Vac", a solution for intramuscular injection, at various times after vaccination in volunteers over 60 years of age
- Trial name
- NCT04587219
- Testing
- Gam-COVID-Vac
- Where
- Russia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Rhinitis, Allergic, Perennial and Seasonal
Pharmacokinetic Study of Levocetirizine Oral Solution
This study will be a single center, open-label, randomized, single dose, in the fasted condition and 2-way crossover study to evaluate the pharmacokinetics, the safety and tolerability of levocetirizine oral solution 5 mg and…
- Trial name
- NCT01622283
- Testing
- Levocetirizine, Cetirizine
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Referral and Consultation
Effectiveness of a Educational Intervention to Improve the Resolution Capacity of Primary Health Care Teams.
There is a great variability in the different primary care teams referral rate. And variability means inappropriateness somewhere in the process of care.
- Trial name
- NCT00140283
- Testing
- Educational interactive intervention
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Catalan Institute of Health
Parkinson's Disease
A Safety, Tolerability and Levodopa Pharmacokinetics Study of Repeated ND0612 in Parkinson's Disease Patients
This is a randomized, placebo-controlled, double-blind, 2-period study evaluating the safety and pharmacokinetics (PK) of ND0612 in Parkinson's disease (PD) patients on an optimized oral levodopa (LD) regimen and experiencing ≥2…
- Trial name
- ND0612/003 (NCT01883505)
- Testing
- ND0612, Entacapone
- Where
- 3 sites in Israel
- Volunteers
- 30 people
- Sponsor
- NeuroDerm Ltd.
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