Clinical trials: Resolution
Glaucoma, Ocular Hypertension
Efficacy and Safety Study of OPC-1085EL Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension
The purpose of this study is to determine the efficacy and safety of OPC-1085EL ophthalmic solution in comparison with carteolol long-acting ophthalmic solution in subjects who are insufficiently responsive to carteolol…
- Trial name
- NCT02105285
- Testing
- OPC-1085EL ophthalmic solution, Carteolol long-acting ophthalmic solution
- Where
- Japan
- Volunteers
- 193 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Absorption, Pharmacokinetic
Clinical Study to Compare the Effect of an Oral Rehydration Solution on the Rate of Absorption of Functional Ingredients
The objective of this study was to compare the individual pharmacokinetics of functional ingredients included in an oral rehydration solution (ORS) with or without the inclusion of active base ingredients (carbohydrate and…
- Trial name
- NCT06524674
- Testing
- Hydration Multiplier + Energy, Hydration Multiplier + Sleep, Energy Comp
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Liquid I.V.
Chronic Heart Failure, Iron-deficiency
Evaluating Iron Protein Succinylate Oral Solution in Treating Chronic Heart Failure and Iron Deficiency
This study aims to evaluate the effect of standard heart failure therapy plus oral solution with protein succinylate iron compared to placebo on the primary end point of 6 minute walk distance at 24th week in patients with…
- Trial name
- NCT03344523
- Testing
- Iron protein succinylate oral solution, standard treatment
- Volunteers
- 600 people
- Sponsor
- Lee's Pharmaceutical Limited
Trapeziometacarpal Osteoarthritis
Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)
Thumb osteoarthritis or trapeziometacarpal osteoarthritis (TMO) is a common and painful form of hand arthritis that limits thumb mobility and hand function, affecting patients' quality of life.
- Trial name
- CASITOA (NCT06401317)
- Testing
- Saline Solution (NaCl 0,9%), Triamcinolone Acetonide
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Université du Québec à Trois-Rivières
Multiple Sclerosis
Immunogenicity and Safety Study of Serum-Free Avonex
To evaluate the immunogenicity of a serum-free pre-formulated solution of Avonex when given to interferon beta naive patients with relapsing/remitting multiple sclerosis.
- Trial name
- NCT00912860
- Testing
- Interferon beta-1a
- Volunteers
- 155 people
- Sponsor
- Biogen
Oesophageal Motility Disorder
Correlation Between Clinical Signs and High-resolution Manometry Data in Children
High resolution oesophageal manometry (HRM) is the gold standard for the diagnosis of oesophageal motility disorder. Standard esophageal manometry has been replaced since 2000 by high resolution manometry.
- Trial name
- NCT03662490
- Testing
- High resolution oesophageal manometry
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Parkinson's Disease
Study on Tolerability of Repeat i.c.v. Administration of sNN0031 Infusion Solution in Patients With PD
This is a phase I, randomised, placebo-controlled study to assess the safety and tolerability of two 2-weeks cycles of i.c.v. administration of sNN0031 infusion solution to patients with PD of moderate severity with persisting…
- Trial name
- NCT02408562
- Testing
- i.c.v. infusion of sNN0031 by an Implanted infusion system, i.c.v. infusion of aCSF by an Implanted infusion system
- Where
- 5 sites in Germany, Sweden and 1 more
- Volunteers
- 1 people
- Sponsor
- Newron Sweden AB
Contrast Induced Nephropathy
Effect of Sodium Bicarbonate Solution in Decreasing the Incidence of Contrast Induced Nephropathy (CIN)
Radio Contrast Induced Nephropathy (RCIN) remains a well recognized complication in patients undergoing diagnostic or interventional procedures requiring radiographic contrast agents.
- Trial name
- NCT00514150
- Testing
- Sodium Bicarbonate plus normal saline 0.9%, normal saline 0.9%
- Where
- Iran
- Volunteers
- 265 people
- Sponsor
- Tehran University of Medical Sciences
Chronic Graft-versus-host Disease
Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2)
To assess the efficacy of R348 Ophthalmic Solutions administered for 12 weeks to subjects evaluated by objective and subjective measures.
- Trial name
- DROPS-2 (NCT02040623)
- Testing
- R348 Ophthalmic Solution, 0.2%, R348 Ophthalmic Solution, 0.5%
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Rigel Pharmaceuticals
Otomycosis
Clinical Study to Assess the Efficacy and Safety of G238 Compared to Clotrimazole Otic Solution in the Treatment of Otomycosis
The purpose of this study is to evaluate the safety and efficacy of G238 for the treatment of otomycosis
- Trial name
- NCT01993823
- Testing
- G238, Clotrimazole
- Where
- Spain
- Volunteers
- 190 people
- Sponsor
- Salvat
Sleep Disturbance, Cognitive Change
Integrating Systematic Data of Medicine to Explore the Solution for Healthy Aging (ISDHA) Phase 4
This project aims to build up the comprehensive health database of geriatric medicine for middle-aged and elderly people in Taiwan.
- Conditions
- Sleep Disturbance, Cognitive Change, Aging
- Trial name
- NCT07414680
- Where
- 2 sites in Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Common Cold, Rhinitis Viral
BАbykids Spray In Common Cold
The purpose of this post market clinical investigation is to demonstrate that Healsea® Babykids alleviates symptoms of the acute rhinitis phase with better efficacy than isotonic saline solution used as Placebo in children above…
- Trial name
- BASICC (NCT05819203)
- Testing
- Healsea Babykids
- Where
- 3 sites in Bulgaria
- Volunteers
- 200 people
- Sponsor
- Lallemand Pharma AG
Malaria, Diarrhea
Integrated Community Case Management Study in Eastern Province, Zambia
This study will provide important evidence to the Ministry of Community Development, Mother and Child Health (MCDMCH) and the Ministry of Health (MOH) on how to effectively implement iCCM with a focus on improving both the flow…
- Conditions
- Malaria, Diarrhea, Pneumonia
- Trial name
- NCT02866097
- Testing
- mHealth inventory management, Supportive supervision, ICCM current standard of care
- Where
- Zambia
- Volunteers
- 3,840 people
- Sponsor
- Zambia Center for Applied Health Research and Development
Endoscopic Retrograde Cholangiopancreatography (ERCP), Choledocholithiasis
Role of Prophylactic Aggressive Hydration to Prevent Post-ERCP Pancreatitis
Endoscopic Retrograde Cholangiopancreatography, also called ERCP, is a procedure used to diagnose and treat disorders of the bile ducts and pancreas.
- Conditions
- Endoscopic Retrograde Cholangiopancreatography (ERCP), Choledocholithiasis, Bile Duct Disorder, Biliary Obstruction
- Trial name
- NCT07417020
- Testing
- Aggressive intravenous hydration with lactated Ringer's solution, Standard intravenous hydration with lactated Ringer's solution
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Lahore General Hospital
Bacterial Infections, Eye Infections
Study of AzaSite Versus Vigamox Concentrations in the Conjunctiva and Aqueous Humor in Subjects Undergoing Routine Cataract Surgery
The purpose of this study is to evaluate the drug concentrations in the conjunctiva and aqueous humor of AzaSite™ compared to Vigamox® in subjects undergoing routine cataract surgery
- Conditions
- Bacterial Infections, Eye Infections, Cataract Extraction
- Trial name
- NCT00575380
- Testing
- AzaSite Eye Drops, Vigamox Eye Drops
- Where
- 13 sites in United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Paget's Disease of Bone
A Research Study to Test the Effectiveness of MK0217 in Patients With Paget's Bone Disease (0217-206)(COMPLETED)
To test the safety, effectiveness of MK0217 when taken once a week for six months in treating patients with Paget's bone disease.
- Trial name
- NCT00480662
- Testing
- alendronate
- Volunteers
- 60 people
- Sponsor
- Organon and Co
Diabetic Macular Edema
OCT-angiography in Diabetic Patients
Around the world there is an increasing incidence of diabetes mellitus, with millions of people affected. In this population, diabetic macular edema (DME) is the most common cause of visual impairment.
- Trial name
- NCT02870803
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Retina Clinic, Sao Paulo, Brazil
Subjects With Cerebral Hemorrhage
Evaluate the Efficacy and Safety of Different Doses of Edaravone Dexborneol Concentrated Solution for Injection Combined With Conventional Medical Therapy in the Treatment of Patients With Cerebral Hemorrhage
The SIM0355-201 trial is a multicenter, randomized, double-blind, placebo-controlled exploratory clinical trial with the main study objective of evaluating the safety and tolerability of different doses of Edaravone Dexborneol…
- Trial name
- NCT05953103
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Simcere Pharmaceutical Co., Ltd
Peritonitis, Intoxication
Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Peritonitis
This study evaluates the efficacy and safety of Rheosorbilact®, solution for infusion ("Yuria-Pharm" LLC), in comparison with Ringer's Lactate, solution for infusion, in a complex therapy of peritonitis.
- Trial name
- NCT03771170
- Testing
- Rheosorbilact®, Ringer lactate
- Where
- 10 sites in Georgia, Moldova and 2 more
- Volunteers
- 180 people
- Sponsor
- Yuria-Pharm
Dry Eye Syndromes
Efficacy and Safety Study for Ecabet Ophthalmic Solution for Treating Dry Eye Syndrome
The purpose of this study is to determine whether ecabet ophthalmic solution is an effective treatment for dry eye syndrome
- Trial name
- NCT00198536
- Testing
- Ecabet 2.83%, Ecabet 3.70%, Vehicle
- Where
- 3 sites in United States
- Volunteers
- 159 people
- Sponsor
- Bausch & Lomb Incorporated
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