Clinical trials: Resolution
Fractures, Bone
Hi-Res IR Thermography for the Diagnosis of Toddler's Fractures
This is a pilot proof of feasibility study to explore the efficacy of high resolution thermal imaging (HRTI) to screen for toddler's fractures.
- Trial name
- NCT05536622
- Testing
- High resolution infrared imaging
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Nasal Allergies, Allergies
Safety and Efficacy of AL-53817 Nasal Spray Solution
The purpose of this study was to determine the maximum tolerated dose of AL-53817 (Stage A) and evaluate the safety and efficacy of AL-53817 for the treatment of allergic rhinitis (Stage B).
- Trial name
- NCT01454505
- Testing
- AL-53817 nasal spray solution, Vehicle nasal spray
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Healthy
Relative Oral Bioavailability of BI 44847 as Suspension Compared to Tablet and the Influence of Food Anf of BI 44847 as Solution Compared to Tablet in Healthy Male Volunteers
Study to investigate the relative oral bioavailability of 400 mg BI 44847 as suspension vs. 400 mg BI 44847 as tablet, to investigate a food effect on the 400 mg tablet pharmacokinetic (PK) and to investigate relative oral…
- Trial name
- NCT02211937
- Testing
- BI 44847 solution, low dose, BI 44847 suspension, high dose, BI 44847 tablet, low dose
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Swallowing Function
Detecting the Changes of Swallowing Function in Oral Cancer Patients
The evidence of swallowing changes in oral cancer patients is still limited. This study aimed to investigated the swallowing changes in these patients by using the videofluoroscopy (VFSS) and high resolution impedance manometry…
- Trial name
- NCT04862637
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- National Taiwan University Hospital
Periodontitis
Diode Laser and Green Indocyanine in the Non-surgical Treatment of Periodontitis
This is a parallel-group, randomized controlled clinical trial aimed to evaluate the clinical and microbiological effects of the adjunctive topical use of diode laser and green indocyanine in the full-mouth ultrasonic debridement…
- Trial name
- NCT04671394
- Testing
- FMUD + DLIG, FMUD + ST
- Volunteers
- 24 people
- Sponsor
- University of Campania Luigi Vanvitelli
Cystic Fibrosis in Adults, Chronic Colonization With Pseudomonas Aeruginosa
Detection of Reductions in Cystic Fibrosis Airway Inflammation While Using Aztreonam Lysine Solution
In cystic fibrosis, there is a critical need for better predictors of treatment response. The investigators have identified a panel of white blood cell biomarkers which can be directly measured as a blood test in subjects with…
- Trial name
- NCT01736839
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- National Jewish Health
Androgenetic Alopecia
A Study of the Safety, Tolerability, and Efficacy of Topical SM04554 Solution in Male Subjects With Androgenetic Alopecia (AGA)
The purpose of this study is to characterize the safety, tolerability, and efficacy of topical SM04554 solution (0.15% and 0.25%) applied to the scalp of male subjects with Androgenetic Alopecia (AGA).
- Trial name
- NCT02275351
- Testing
- Topical SM04554 solution, Topical vehicle solution
- Where
- 24 sites in United States
- Volunteers
- 302 people
- Sponsor
- Biosplice Therapeutics, Inc.
Oral Cancer Screening
Non-invasive Methods for Oral Cancer Screening
Oral cancer is a common cancer worldwide, with approximately 250,000 new cases annually and a high mortality rate. Its major risk factors include smoking, alcohol consumption, and betel nut chewing.
- Trial name
- HRME (NCT07249437)
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Nail Psoriasis
Study to Evaluate the Efficacy and Safety of P-3073 Nail Solution in the Treatment of Nails Affected by Psoriasis
The purpose of this study is to confirm the clinical efficacy and the safety of P-3073 in patients affected by isolated psoriatic nail(s) and/or those with psoriatic nails and concomitant mild to moderate plaque psoriasis.
- Trial name
- NCT02606760
- Testing
- P-3073, Vehicle of P-3073
- Where
- 7 sites in Bulgaria, Czechia and 5 more
- Volunteers
- 378 people
- Sponsor
- Polichem S.A.
Skin Diseases, Infectious
Effect of an Antiseptic Solution on the Skin Microbiome
The objective of this study is simulate the clinical use of an antiseptic solution in a 24 hour window and the recovery to baseline conditions at 1 month following application.
- Trial name
- NCT05608382
- Testing
- sterile Phosphate Buffer Saline, SGW13
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Center for Innovation and Research Organization
Surgical Site Infection, Surgical Wound
Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies
The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients…
- Conditions
- Surgical Site Infection, Surgical Wound, Surgical Incision, Emergency Laparotomies
- Trial name
- NCT05989386
- Testing
- 0.9% saline solution, Povidone-iodine Swab
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Dow University of Health Sciences
Blepharitis
Safety and Efficacy Study of AzaSite® in Subjects With Blepharitis
The purpose of this study is to evaluate the safety and efficacy of AzaSite® ophthalmic solution, 1% on signs \& symptoms of blepharitis and tear cytokine and eyelid bacterial load levels
- Trial name
- NCT00629941
- Testing
- AzaSite®
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Merck Sharp & Dohme LLC
Respiratory Distress Syndrome, Adult
Evaluation of Safety & Efficacy of BIO-11006 Inhalation Solution in Patients With ARDS
This Phase IIa pilot study is a placebo controlled, multicenter study to evaluate safety and efficacy of aerosolized BIO-11006 Inhalation Solution in ARDS patients.
- Trial name
- NCT03202394
- Testing
- BIO-11006
- Where
- 5 sites in United States
- Volunteers
- 38 people
- Sponsor
- BioMarck Pharmaceuticals, Ltd.
Alpha-1 Antitrypsin Deficiency
The Use of High Resolution Chest Computed Tomography in Alpha-1 Antitrypsin Deficiency
Individuals with a deficiency of alpha-1 antitrypsin (AAT) often develop emphysema. Traditional lung function tests may not be the most accurate way to measure the progression of emphysema.
- Trial name
- QUANTUM-1 (NCT00532805)
- Where
- 7 sites in United States
- Volunteers
- 49 people
- Sponsor
- Medical University of South Carolina
Keratoconus, Pellucid Marginal Corneal Degeneration
Safety & Effectiveness of the PXL-Platinum 330 System for CXL Using Riboflavin Solution
Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Collagen Cross-linking in Eyes With Corneal Thinning Conditions
- Conditions
- Keratoconus, Pellucid Marginal Corneal Degeneration, Corneal Degeneration, Corneal Ectasia
- Trial name
- NCT04667572
- Testing
- PXL-330 Platinum device for crosslinking with Peschke riboflavin solution
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Cornea Associates of Texas
Non-infectious Anterior Uveitis
SOLACE Trial - A Phase 3 Trial in Subjects With Non-infectious Anterior-uveitis.
A Phase 3, randomized, double-masked, vehicle-controlled trial to evaluate the safety and efficacy of ADX-102 ophthalmic solution in Subjects with non-infectious anterior-uveitis.
- Trial name
- NCT03131154
- Testing
- ADX-102 Ophthalmic Solution (0.5%), Vehicle of ADX-102 Ophthalmic Solution
- Where
- 27 sites in United States
- Volunteers
- 123 people
- Sponsor
- Aldeyra Therapeutics, Inc.
End-stage Renal Disease (ESRD), Peritoneal Dialysis (PD)
Amino Acid (15) Peritoneal Dialysis Solution for Nutritional Improvement in Peritoneal Dialysis Patients
The goal of this clinical trial is to assess whether Amino Acid (15) Peritoneal Dialysis Solution can improve the nutritional status of adults with end-stage kidney disease who have received peritoneal dialysis for 6 months or…
- Conditions
- End-stage Renal Disease (ESRD), Peritoneal Dialysis (PD), Nutritional Status, Renal Replacement Therapy
- Trial name
- AA15-PD-Nut-SH (NCT07370441)
- Testing
- amino acid (15) peritoneal dialysis solution
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai 10th People's Hospital
Asthma
Multicentre Post-market Study of Ectoin® Inhalation Solution in Treatment of Asthma.
The goal of this multi-centre, prospective, open-label, single-arm, post-market clinical follow-up study is to further strengthen the already existing clinical evidence for supportive treatment and symptoms alleviation in asthma…
- Trial name
- EIL-AST (NCT05699941)
- Testing
- Ectoin® Inhalation Solution
- Where
- 5 sites in Poland
- Volunteers
- 204 people
- Sponsor
- Bitop AG
Preoperative Skin Preparation
Evaluating Safety and Effectiveness of Octenidine Dihydrochloride
The purpose of this study is to evaluate the safety and effectiveness of a topical antiseptic for preoperative skin preparation
- Trial name
- NCT03140254
- Testing
- Chlorhexidine gluconate, N,N'-(1,10-decanediyldi-1(4H)-Pyridinyl-4-ylidene)-Bis-(1-octanamine) Dihydrochloride
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Warts, HPV
Study With Candida Antigen for Treatment of Warts
The purpose of this study is to look at how people respond to the treatment of warts through use of the Candida antigen to get an immune response to rid the body of human papillomavirus (HPV).
- Trial name
- NCT00569231
- Testing
- Candida Antigen
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Arkansas
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