Clinical trials: Resolution of Pathologic Process
Breast Carcinoma, Prostate Cancer Surgery
High-resolution PET-CT Specimen Imaging for the Perioperative Visualization of Resection Margins
These are patients in whom a benign or malignant tumor was recorded requiring surgery. During that surgery, the surgeon will cut away the tumor as part of the treatment of the disease.
- Conditions
- Breast Carcinoma, Prostate Cancer Surgery, Thyroid Cancer, Parathyroid Adenomas
- Trial name
- NCT06835426
- Testing
- Single intravenous injection of the radiotracer, Imaging resected specimen using the high-resolution PET-CT specimen imager
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Intracranial Arterial Stenosis
Resuvastatin Treatment for Symptomatic Middle Cerebral Artery Stenosis Based on High-resolution Magnetic Resonance Imaging
1. It is a multicenter, open-label, sing arm study to evaluate the effects of treatment of Rosuvastatin 10-20mg in volume and morphology of atherosclerotic plague by reducing LDL-C level to or less than 70mg/dl. 2.
- Trial name
- REALM (NCT02041117)
- Testing
- Rosuvastatin
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Beijing Tiantan Hospital
Dehydration
Measuring Pain and Hydration After Tonsillectomy
Pain after tonsillectomy remains a key barrier during the post operative period. The published return rate to the emergency department for hydration and pain control is approximately 4%.
- Trial name
- NCT02011230
- Testing
- Hoist Group
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Intraventricular Hemorrhage
Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III
The overall objective of this Phase III clinical trial is to obtain information from a population of 500 ICH subjects with intraventricular hemorrhage (IVH), representative of current clinical practice and national demographics…
- Trial name
- CLEAR III (NCT00784134)
- Testing
- Alteplase, Normal saline
- Where
- 81 sites in United States, Brazil and 7 more
- Volunteers
- 500 people
- Sponsor
- Johns Hopkins University
Cataract, Presbyopia
Clinical Evaluation and Comparison of the Tecnis Symfony Optiblue and Tecnis Symfony IOLs
The goal of this clinical study is to compare the Tecnis Symfony Optiblue intraocular lens implant to the Tecnis Symfony intraocular lens implant in patients over 22 years old with cataracts in both eyes.
- Trial name
- NCT06567834
- Testing
- Tecnis Symfony Optiblue/Tecnis Symfony Optiblue Toric (Models ZXR00V/ZXW150), Tecnis Symfony/Tecnis Symfony Toric (Models ZXR00/ZXT150)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Empire Eye and Laser Center
Vital Pulp Therapies, Pulpotomy
Comparison of Sodium Hypochlorite Gel and Solution With and Without Nanoparticles for Postoperative Pain After Pulpotomy in Permanent Mandibular Molars
This randomized clinical trial aims to compare the effect of 2% sodium hypochlorite gel and solution, with and without chitosan nanoparticles, on postoperative pain following pulpotomy in mature permanent mandibular molars with…
- Conditions
- Vital Pulp Therapies, Pulpotomy, Irriversible Pulpitis, Postoperative Pain
- Trial name
- NaOCl Pulpotom (NCT07774130)
- Testing
- Sodium Hypochlorite gel 2%, Sodium hypochlorite gel 2% with chitosan nano particles, Sodium hypochlorite solution 2% with chitosan nanoparticles
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Gastroparesis
Vagus Nerve Response in Gastroparesis Patients
This study aims to characterize how vagus nerve compound action potentials (CNAPs) conduct along the vagus nerve in gastroparetic patients receiving GES therapy using a flexible, non-invasive multielectrode array (MEA).
- Trial name
- NCT04207996
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Indiana University
Acute Appendicitis
Antibiotics vs. Placebo in Acute Uncomplicated Appendicitis
Appendicectomy has been the treatment of acute appendicitis for over a hundred years. Appendicectomy, however, includes operative and postoperative risks despite being a "routine" operation.
- Trial name
- APPACIII (NCT03234296)
- Testing
- Ertapenem
- Where
- Finland
- Volunteers
- 147 people
- Sponsor
- Turku University Hospital
End Stage Renal Disease
Safety and Efficacy of the Addition of Alanyl-Glutamine-Dipeptide to Dialysis Solution in Peritoneal Dialysis
Peritoneal dialysis (PD) is a cost effective and safe form of renal replacement therapy in patients suffering from end stage renal disease.
- Trial name
- NCT01353638
- Testing
- Dipeptiven (Alanyl-glutamine-dipeptide)
- Where
- Austria
- Volunteers
- 25 people
- Sponsor
- Christoph Aufricht
Breast Cancer, Metastatic Breast Cancer
High Resolution 3D Diffusion-weighted Breast MRI
The purpose of this study is to determine how well a new MRI technique called "High resolution 3D diffusion-weighted breast MRI" detects breast cancer.
- Trial name
- NCT01315106
- Testing
- Magnetic Resonance Image Scanner
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
HIV
Imaging Trial of the Distribution of Topical Gel in the Human Vagina: Enhanced MRI Techniques to Increase Resolution
This study will assess the distribution of topical gel in the human vagina, using enhanced MRI techniques. The number and size of uncovered areas will be studied, and the upper genital tract will be examined for the presence of…
- Trial name
- NCT00260767
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Biosyn
Opioid Induced Pharyngeal and Esophageal Dysfunction
Opioid Effects on Swallowing and Esophageal Sphincter Pressure
The purpose of this study is to determine whether a dopamine receptor antagonist metoclopramide can counteract opioid induced effects on esophageal motility and lower esophageal sphincter.
- Trial name
- NCT01191645
- Testing
- naloxone, remifentanil, Sodium Chloride
- Where
- Sweden
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Atrial Fibrillation
High-resolution MRI of Atrial Fibrillation Patients Prior to Focal Impulse and Rotor Modulation (FIRM) Ablation
Patients undergoing FIRM guided ablation of atrial fibrillation will undergo high resolution MRI imaging to determine correlation of underlying anatomic fibrotic regions with FIRM targeted sites for ablation.
- Trial name
- NCT03444337
- Testing
- Catheter Ablation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Kidney Failure, Chronic, Catheter-Related Infections
Study Assessing Safety & Effectiveness of a Catheter Lock Solution in Dialysis Patients to Prevent Bloodstream Infection
The purpose of this study is determine safety and effectiveness of Neutrolin, a catheter lock solution, for prevention of central venous catheter associated bloodstream infection in hemodialysis patients.
- Trial name
- NCT02651428
- Testing
- Neutrolin, Heparin
- Where
- 5 sites in United States
- Volunteers
- 806 people
- Sponsor
- CorMedix Therapeutics
Bronchiolitis Obliterans Syndrome
Correlation of Lung Biopsy, BAL, and High Resolution CT Scan in Lung Transplantation
A major source of graft failure and dysfunction in lung transplantation is known to be bronchiolitis obliterans (BO)and its clinical correlate called bronchiolitis obliterans syndrome(BOS).
- Trial name
- NCT00528853
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Chicago
COPD Symptoms After Coil Procedure
Chronic Obstructive Pulmonary Disease (COPD) Co-Pilot AIR Substudy of CLN0014
The purpose of undertaking CLN0020, which was a Substudy of the European Coil registry (CLN0014), was to investigate the use of COPD Co-Pilot AIR™, a COPD disease management program manufactured and operated by HGE Health Care…
- Trial name
- Co-Pilot Air (NCT03267992)
- Testing
- COPD Co-Pilot AIR App
- Where
- 2 sites in Switzerland
- Volunteers
- 9 people
- Sponsor
- Boston Scientific Corporation
Mitochondrial Diseases
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip
Mitochondrial diseases are complex diseases with great clinical and genetic heterogeneity and their diagnosis is difficult. The Medical Genetics Department includes among its activities the diagnosis of these diseases.
- Trial name
- ACPA HR (NCT03857880)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Anal High Grade Squamous Intraepithelial Lesion
The Effectiveness of High Resolution Microendoscopy for People Living With HIV
The investigators have developed a portable, battery-operated, mobile high-resolution microendoscope (mHRME) that provides subcellular images of the anal epithelium, delineating the cellular and morphologic changes associated…
- Trial name
- NCT04563754
- Testing
- mHRME (Mobile High resolution microendoscope), Proflavine Hemisulfate, High resolution anoscopy
- Where
- 3 sites in United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Colorectal Cancer
Difference of Surgical Site Infection Between Using Sodium Picosulfate Solution(PicosolutionⓇ) and Oral Sulfate Tablet(ORA·FANGⓇ) in Colorectal Cancer Surgery
This is a prospective randomized study to evaluate the difference in the rate of surgical site infection between the patients who used Sodium Picosulfate solution(PicosolutionⓇ) and tablet Oral Sulphate Solution(ORA·FANGⓇ) for…
- Trial name
- NCT04593446
- Testing
- Oral Sulfate Tablet(ORA·FANGⓇ), Sodium Picosulfate Solution(PicosolutionⓇ)
- Where
- South Korea
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Epilepsy
Concomitant High-resolution Recording of Haemodynamic and Electrical Activities of Children With Typical or Atypical Absence Seizures
This study, conducted in children with typical or atypical "absence" epilepsy, will consist of noninvasive recording of the metabolic activity of the brain concomitantly with electroencephalographic recording during seizures…
- Trial name
- Absence (NCT02819427)
- Testing
- Near Infra Red Spectroscopy (NIRS), Electroencephalography (EEG)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
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