Clinical trials: Respiration; Artificial
Dyspnea
Artificial Intelligence to Improve Physicians' Interpretation of Chest X-Rays in Breathless Patients
Identifying the cause of breathlessness in acute patients in the emergency department is critical and challenging. The chest X-ray is central but challenging to read for non-radiologist physicians.
- Trial name
- XRAI (NCT05117320)
- Testing
- AI support
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Respiratory Failure
Patient-Ventilator Dyssynchrony Detection With a Machine Learning Algorithm
This is a diagnostic study aiming to compare accuracy to detect and classify patient-ventilator dyssynchronies by a machine learning algorithm, compared to the gold-standard defined as dyssynchronies diagnosed and classified by…
- Trial name
- NCT06506123
- Testing
- Artificial Intelligence Detection and Classification of Patient-Ventilator Dyssynchronies
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Sao Paulo General Hospital
Respiration, Artificial
Practice of Mechanical Ventilation in Patients With Severe Brain Injury in China
The mechanical ventilation strategy has changed over years worldwide. Several international researches have been conducted to study the association of the use of mechanical ventilation with clinical outcomes.
- Trial name
- NCT02517073
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Capital Medical University
Respiratory Insufficiency
Respiratory Mechanics and Patient-ventilator Asynchrony Index in Patients With Invasive Mechanical Ventilation
The objective of the study is to estimate the incidence of asynchrony and to assess its relationship with respiratory mechanics. This will be a prospective cohort study, including patients under invasive mechanical ventilation.
- Trial name
- EpiSync (NCT02687802)
- Testing
- mechanical ventilation
- Where
- Brazil
- Volunteers
- 103 people
- Sponsor
- University of Sao Paulo General Hospital
COPD (Chronic Obstructive Pulmonary Disease), Artificial Intelligence
A Prospective, Multicenter, Portable Pulmonary Function Comparison Study Aimed at Evaluating the External Clinical Validation of the Chronic Obstructive Pulmonary Disease Auxiliary Diagnostic Software LH-002 (Version: 2.0.0) in Clinical Diagnosis Accuracy
Chronic Obstructive Pulmonary Disease (COPD) is widely underdiagnosed in low- and middle-income countries and regions, due to the lack of accessible tools.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Artificial Intelligence, Cough, Diagnosis
- Trial name
- NCT07888712
- Where
- China
- Volunteers
- 466 people
- Sponsor
- Ruijin Hospital
Respiratory Failure, Mechanical Ventilation Complication
Patient-ventilator Asynchrony During Mechanical Non-Invasive Assisted-ventilation in Pediatric Patients (NavPed-NI)
The purpose of this study is to document the prevalence and type of asynchronies incidence during non-invasive mechanical ventilation in pediatric patients breathing under pressure support.
- Trial name
- NavPed-NI (NCT01238757)
- Testing
- Non-invasive Ventilation under Pressure Support, Non-Invasive ventilation under NAVA
- Where
- Switzerland
- Volunteers
- 7 people
- Sponsor
- University Hospital, Geneva
Respiration, Artificial, Critical Illness
Adjunctive Clonidine in the Sedation of Mechanically Ventilated Children
Almost all critically ill children who are mechanically ventilated require sedation and analgesia. Providing effective sedation for children in the PICU requires careful balancing of the need for sedation with the adverse effects…
- Conditions
- Respiration, Artificial, Critical Illness, Conscious Sedation, Deep Sedation
- Trial name
- NAPS Pilot (NCT00959062)
- Testing
- clonidine
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Hamilton Health Sciences Corporation
Respiration Disorders
Randomized Study of Propofol Versus Fentanyl and Midazolam in Pediatric Patients Requiring Mechanical Ventilation and Sedation Therapy
OBJECTIVES: I. Assess the degree of amnesia afforded by study sedatives relative to the patient's intensive care unit experiences. II.
- Trial name
- NCT00004424
- Testing
- fentanyl, Midazolam, propofol
- Volunteers
- 120 people
- Sponsor
- FDA Office of Orphan Products Development
Out-of-Hospital Cardiac Arrest, Pulmonary Ventilation
CAvent-Ventilation During Advanced Cardiopulmonary Resuscitation in Out-of-hospital Cardiac Arrest- an Observational Study
The aim of this observational study is to investigate how ventilations is given during cardiopulmonary resuscitation (CPR) given by advanced life support providers (ALS).
- Trial name
- CAvent (NCT04237727)
- Testing
- Fluxmed GrH portable pneumotachograph
- Where
- 5 sites in Netherlands, Sweden
- Volunteers
- 241 people
- Sponsor
- Uppsala University
Respiration, Artificial
A Cluster Randomized Trial to Improve Weaning and Extubation From Mechanical Ventilation in Community Hospitals
Protocol directed weaning has been shown to reduce the duration of mechanical ventilation for patients admitted to the intensive care unit (ICU) of tertiary centres.
- Trial name
- NCT00157287
- Testing
- Evidence based weaning protocol
- Where
- 11 sites in Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Respiratory Distress Syndrome
Sustained Lung Inflation in the Delivery Room in Preterm Infants at High Risk of Respiratory Distress Syndrome
BACKGROUND. Sustained lung inflation (SLI) associated to an adequate PEEP may help the efficacy of the respiratory effort in lung of preterm infants at risk for respiratory distress syndrome (RDS) and reduce need of mechanical…
- Trial name
- SLIS (NCT01440868)
- Testing
- Sustained lung inflation
- Where
- Italy
- Volunteers
- 276 people
- Sponsor
- University of Florence
Delirium, Agitation
A Comparison of Dexmedetomidine and Haloperidol in Patients With Intensive Care Unit (ICU)-Associated Agitation and Delirium
The purpose of the study is to determine whether dexmedetomidine is a more effective medication than haloperidol in the treatment of agitation and delirium in patients receiving mechanical ventilation in an intensive care unit.
- Conditions
- Delirium, Agitation, Ventilator Weaning, Respiration, Artificial
- Trial name
- Dex (NCT00505804)
- Testing
- dexmedetomidine, haloperidol
- Volunteers
- 20 people
- Sponsor
- Austin Health
Respiration, Artificial, Epidemiology
Mechanical Ventilation Epidemiology in Argentina.
How is the epidemiology of mechanically ventilated patients in the intensive care units of Argentina?
- Trial name
- EpVAr2019 (NCT04107467)
- Where
- 154 sites in Argentina
- Volunteers
- 950 people
- Sponsor
- Argentinian Intensive Care Society
Delirium
Delirium in Mechanically Ventilated Patients
The overall purpose of this trial is to assess the relationship between a daily awakening from sedation and the prevalence of delirium, and in doing so better characterize delirium in the ICU.
- Trial name
- NCT00919698
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Chicago
Chronic Obstructive Pulmonary Disease
Intellivent ASV in Chronic Obstructive Pulmonary Disease Patients in the ICU
This study will evaluate the effect of a fully closed loop ventilation mode (Intellivent ASV) on the duration of ventilation compared to conventional modes in COPD patients.
- Trial name
- NCT02651935
- Testing
- Intellivent ASV
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
Respiratory Insufficiency, Weaning, Ventilator
Parasternal Intercostal Ultrasound vs RSBI for Weaning Prediction
Mechanical ventilation is essential in the management of critically ill patients, but deciding the proper time to wean and extubate remains a significant challenge.
- Conditions
- Respiratory Insufficiency, Weaning, Ventilator, Respiration, Artificial, Intensive Care Units
- Trial name
- NCT07144878
- Testing
- Parasternal Intercostal Ultrasound and RSBI Assessment
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Benha University
Acute Respiratory Distress Syndrome, Pneumonia in Children
Using Artificial Intelligence To Improve Ventilator Settings For Intensive Care Patients
This observational study aims to determine whether an AI-assisted decision support system can improve clinical outcomes for mechanically ventilated pediatric patients (aged 1 month to 18 years) in the PICU, compared to standard…
- Conditions
- Acute Respiratory Distress Syndrome, Pneumonia in Children, Respiratory Failure (Pediatric Patients)
- Trial name
- NCT07592039
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Wu Rongzhou
Respiration, Artificial
Ventilatory Weaning Guided by a New Index
Mechanical ventilation (MV) is an essential therapy for patients with acute respiratory failure. The ventilatory weaning process should be started when the precipitating causes of the use of the ventilatory prosthesis are…
- Trial name
- NCT04512677
- Testing
- Timed Inspiratory Effort (TIE index)
- Where
- 2 sites in Brazil
- Volunteers
- 144 people
- Sponsor
- Universidade Federal Fluminense
Respiration, Artificial, COVID-19
Healthcare-associated Infections in Severe COVID-19 During 2020
In patients who develop ARDS due to SARS-CoV-2 (CARDS), a longer duration of invasive mechanical ventilation (IMV) and ICU stay has been reported compared to ARDS not associated with SARS-CoV-2.
- Conditions
- Respiration, Artificial, COVID-19, Health Care Associated Infection
- Trial name
- COVIACS (NCT04819165)
- Testing
- COVID-19
- Where
- Argentina
- Volunteers
- 252 people
- Sponsor
- Sanatorio Anchorena San Martin
Respiration, Artificial, Critical Care
Aerosol Therapy in Intensive Care Units
Unlike in the outpatient setting, delivery of aerosols to ICU patients may be considered complex, particularly in ventilated patients.
- Trial name
- ATICU (NCT03597334)
- Testing
- aerosol therapy
- Where
- China
- Volunteers
- 1,095 people
- Sponsor
- lvshan