Clinical trials: Respiration Rate Detection
Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8
18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases
This early phase I trial tests the use of a radioactive tracer (a drug that is visible during an imaging test) known as 18F-FMAU, for imaging with positron emission tomography/computed tomography (PET/CT) in patients with brain…
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Glioma, Malignant Brain Neoplasm
- Trial name
- NCT04752267
- Testing
- Computed Tomography, 18F-FMAU, Multiparametric Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Southern California
Lung Cancer
Clinical and Molecular Staging of Lung Cancer Stages I and IIp
The classification of lung cancer (LC) according to the degree of anatomical extension (TNM) allows the estimation of the prognosis of the patient, although its accuracy is limited.
- Trial name
- NCT03286036
- Testing
- biomarkers
- Where
- 4 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Corporacion Parc Tauli
Lung Cancer
Validation of Multiparametric Models and Circulating and Imaging Biomarkers to Improve Lung Cancer EARLY Detection.
CLEARLY will focus on validation of a multifactorial "bio-radiomic" protocol for early diagnosis of lung cancer that combines circulating biomarkers and radiomic analysis.
- Trial name
- CLEARLY (NCT04323579)
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Neoplastic Cells, Circulating
The Detection of Circulating Tumor Cells (CTCs) in Patients With Lung Cancer Undergoing Cryosurgery Combined With DC-CIK Treatment
Circulating tumor cells (CTCs) have the potential to provide a surrogate for'real-time biopsy' of tumor biological activity. Enumeration and molecular characterization of CTCs in lung cancer could play an important role in…
- Trial name
- NCT02412384
- Testing
- Flow cytometry (FCM), RT-PCR
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
Fluorescence-navigated Thoracoscopy for Detection of Small Pulmonary Nodules
Fluorescence-navigated thoracoscopic imaging with indocyanine green (ICG) is a novel technique for detection of small pulmonary nodules other than traditional radiography or intraoperative palpation.
- Trial name
- NCT04165603
- Testing
- Preoperative Infusion of Indocyanine Green
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Peking University People's Hospital
HIV Infections, Hypertension
ENHANCE-EvideNce Led Co-created HeAlth Systems interventioNs for MLTCs CarE
The goal of this study is to determine the effect of the ENHANCE intervention in improving clinical outcomes and evaluating the effects of the intervention on implementation processes and outcomes.
- Conditions
- HIV Infections, Hypertension, Diabetes Mellitus, Asthma
- Trial name
- ENHANCE (NCT06248190)
- Testing
- ENHANCE intervention (health systems)
- Where
- 32 sites in South Africa
- Volunteers
- 1,837 people
- Sponsor
- University of KwaZulu
Pulmonary Diseases, Fever
Pneumocystis Primary Infection in Non-immunosuppressed Infants
To determine the prevalence of P. jirovecii in nasopharyngeal aspirations of neonates and infants hospitalized for symptomatic respiratory infection.
- Trial name
- CAPRI-PC (NCT03740646)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Brest
Pulmonary Invasive Aspergillosis
Application of an Electronic Nose in the Early Detection of ASpergillosis
The purpose of this study is to establish the accuracy with which the eNose can discriminate patients with invasive pulmonary aspergillosis from controls.
- Trial name
- AENEAS (NCT01395446)
- Where
- Netherlands
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
COVID-19
Detection of Anti-COVID-19 Antibody Levels in an Hospital Population
COVID-19 (SARS-CoV-2) infection in health professionals represent a significant criticality both for the risk of spreading the disease and for the organizational aspects that follow.
- Trial name
- NCT04387929
- Testing
- Detection of anti-COVID-19 antibody level
- Where
- Italy
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Pancreatic Adenocarcinoma, Lung Cancer
KEBI-Cyto Study - Use of the Biocartis Idylla
Use of the Biocartis Idylla ™ platform for the detection of Epidermal Growth Factor Receptor, B-RAF and K-RAS proto-oncogene mutations in liquid based cytology specimens and blood plasma samples from patients with non small cell…
- Trial name
- NCT04236102
- Testing
- Biocartis Idylla platform - real time PCR detecting EGFR, KRAS and BRAF mutations in liquid based cytology and blood plasma samples
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Royal Cornwall Hospitals Trust
Community-Acquired Pneumonia
Early Molecular Detection Technique Coupled With Urinary Test of Infectious Agents Responsible of Children CAP
Community-Acquired Pneumonia (CAP) of children are a recurrent pathology with multiple severity scores. The etiology is never really identified, and the initial treatment is always based on probabilistic antibiotics, in the case…
- Trial name
- OptiPAC (NCT02668237)
- Testing
- OptiPAC, Usual care
- Where
- 11 sites in France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Advanced Malignant Mesothelioma, Localized Malignant Mesothelioma
EF5 in Detecting Oxygen Level and Blood Vessels in Tumor Cells of Patients Undergoing Photodynamic Therapy for Intraperitoneal or Pleural Cancer
This phase II trial is studying how well EF5 works in detecting oxygen level and blood vessels in tumor cells of patients who are undergoing photodynamic therapy for intraperitoneal or pleural cancer.
- Conditions
- Advanced Malignant Mesothelioma, Localized Malignant Mesothelioma, Malignant Ascites, Primary Peritoneal Cavity Cancer
- Trial name
- NCT00028782
- Testing
- etanidazole, therapeutic conventional surgery, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Cancer Institute (NCI)
Lung Cancer
Intensified Follow-up of Lung Cancer Using Weekly Questionnaires Via the Internet
This randomized controlled trial (RCT) will test if weekly supplementary internet-based self-monitoring of 12 core symptoms can increase survival in Danish lung cancer patients during follow-up or maintenance treatment.
- Trial name
- ProWide (NCT03608410)
- Testing
- Weekly Internet based PRO questionnaires
- Where
- Denmark
- Volunteers
- 494 people
- Sponsor
- Regional Hospital West Jutland
Colon Cancer
PET Respiratory Gating to Detect Hepatic Metastasis in Patients With Colon Cancer
This study is to examine if there is improved sensitivity in detecting hepatic lesions using respiratory gating and if there is an improvement in confidence defining lesions as benign or malignant.
- Trial name
- NCT01401309
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Southwestern Regional Medical Center
Covid19, RSV Infection
Sample Collection Study to Aid Evaluation of an Influenza A/B, Respiratory Syncytial Virus & COVID-19 Virus POC Test
Collection of Nasal Swabs, Throat Swabs and Saliva Samples from patients presenting at their designated care or testing facility displaying symptoms of either Influenza, Respiratory Syncytial Virus (RSV), SARS-CoV-2 or those who…
- Conditions
- Covid19, RSV Infection, Influenza Type A, Influenza Type B
- Trial name
- INFORM (NCT04782336)
- Testing
- Sample Collection
- Where
- 6 sites in United Kingdom
- Volunteers
- 79 people
- Sponsor
- LumiraDx UK Limited
Multiple Pulmonary Nodules, Pulmonary Emphysema
Diagnostic Value of Ultralow-dose Computed Tomography for the Detection of Pulmonary Nodules and Lung Parenchym Alterations Compared to Standard-dose CT
To investigate the diagnostic value of ultralow-dose computed tomography in the detection of pulmonary nodules and lung parenchym alterations (e.g. emphysema) compared to standard-dose-CT.
- Trial name
- RADFL (NCT02468609)
- Testing
- Ultralow-Dose-CT
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- Cantonal Hospital of St. Gallen
SARS-CoV Infection, Coronavirus
Should Palatine Tonsils be Included in the Oropharyngeal Swab for SARS-CoV-2 Molecular Testing?
Citizens who undergo testing for COVID-19 at one of two Testcenters in Copenhagen Captial Region will be invited to participate in the study.
- Conditions
- SARS-CoV Infection, Coronavirus, Corona Virus Infection
- Trial name
- NCT05611203
- Testing
- An Oropharyngeal swab
- Where
- 2 sites in Denmark
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Atelectasis Neonatal, Pneumothorax and Air Leak
Detection of Atelectasis or Pneumothorax and Resolution With Electrical Impedance Tomography (EIT) in Newborn Infants
To validate the benefits of recognizing asymmetric lung disease like atelectasis and pneumothorax in neonatal respiratory distress syndrome using electrical impedance tomography
- Trial name
- DePIcT (NCT04848727)
- Testing
- Detecting asymmetric lung disease like atelectasis or pneumothorax with electrical impedance tomography (EIT)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sharp HealthCare
Covid19
Comparison of Detection of SARS-CoV2 (COVID-19) Between Nasopharyngeal Swab Specimens and Those Obtained by Salivary Sputum
Multicenter observational study of diagnostic test validation (Research Involving the Human Person, type 3) In addition to the diagnosis by the reference method (nasopharyngeal swab), the patient will be asked to provide a saliva…
- Trial name
- COVISAL (NCT05024461)
- Testing
- Salivary test for COVID19
- Where
- French Guiana
- Volunteers
- 1,159 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Lung Cancer Screening
Lung Cancer Screening for Early Detection of Suspicious Lung Nodules in Latin America(LUCAS-LATAM)
Prospective study to assess lung cancer screening with low dose CT scan (LDCT) in Latin America (LATAM) and prospectively evaluate chest-XRay analyzed with artificial intelligence (AI) using qXRin (QURE ai) at the initial visit…
- Trial name
- LUCAS-LATAM (NCT07524803)
- Testing
- Chest X-Ray, Low Dose CT scan
- Where
- 2 sites in Colombia, Costa Rica
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Latin American Consortium for the Lung Cancer Research