Clinical trials: Respiration Rate Detection
Cystic Fibrosis (CF), New Diagnostics
Study to Enable New Diagnostics for Pulmonary Microbes in People With CF
Sputum culture has been the best approach to detect harmful bacteria in the lungs of people with cystic fibrosis (CF). With the widespread use of new CF therapies (like Trikafta and Alyftrak), it is more difficult for people with…
- Trial name
- SEND-CF (NCT07312734)
- Where
- 9 sites in United States
- Volunteers
- 300 people
- Sponsor
- Chris Goss
Sleep Disordered Breathing (SDB), Sleep Apnea
Detection of Sleep Stages and Arousals Using Neural Network Classifiers
The objective of this clinical study is to evaluate the accuracy of the Smart Mask V1 System (herein 'Smart Mask') in measuring sleep stages-Stage N1/N2, Stage N3, Rapid Eye Movement (herein 'REM'), and WAKE-arousals, and the…
- Trial name
- SSAM (NCT07136272)
- Testing
- SSAM, Polysomnography, EnsoSleep
- Where
- 3 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Pathway Medtech, LLC.
Tonsillitis
Detection of Group A Streptococcus (GAS) in Oral Cavity
The investigators intend to screen children who are suspected of having GAS tonsillitis. From each child we will take a throat culture and saliva sample to screen for molecular evidence of GAS.
- Trial name
- NCT02972437
- Testing
- sample taking
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Pleural Neoplasms, Mesothelioma
The ISET (Isolation by Size of Epithelial Tumor Cells) and the CellSearch Methods in Malignant Pleural Mesothelioma
Malignant pleural mesothelioma (MPM) has a growing incidence and in spite of early diagnostic, their outcome remains dismal. The evolution of MPM is often local with rare distant metastases.
- Conditions
- Pleural Neoplasms, Mesothelioma, Pneumothorax, Parathyroid Neoplasms
- Trial name
- NCT01776385
- Testing
- Blood sampling, Control Group
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pneumothorax, Cardiac Surgery
Nurse-performed Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax.
This is a prospective, single-center, observational, cross-sectional cohort study, comparing nurse-performed bedside lung ultrasound to standard portable CXR, for the detection of pneumothorax in the cardiac surgery patient…
- Trial name
- NCT04678726
- Testing
- Lung ultrasound assessment for ruling out pneumothorax
- Sponsor
- University Health Network, Toronto
Interstitial Lung Disease
Endobronchial Ultrasound Transbronchial Needle Aspiration Of Enlarged Mediastinal In Interstitial Lung Disease
The aim of this study is to assess the findings of mediastinal/hilar LN sampling by EBUS-TBNA in patients with non-sarcoidosis interstitial lung disease ( ILD) who demonstrate LN enlargement on chest imaging.
- Trial name
- NCT04331548
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Lung Cancer (Suspected or Confirmed), Cryoablation
One-stop Diagnosis and Treatment for Suspected Lung Cancer: Combined RBS, nClE, OBCT and Ablation
Using RBS as the navigation and treatment platform, precisely navigate to the target lesion. Utilize r-EUBS and nCLE to identify the lesion, and when the confocal AI model recognizes the lesion as malignant, perform a biopsy.
- Conditions
- Lung Cancer (Suspected or Confirmed), Cryoablation, Robotic Bronchoscopy System, Confocal Laser Endomicroscopy
- Trial name
- One-stop (NCT07521618)
- Testing
- Ablation
- Volunteers
- 30 people
- Sponsor
- Guangzhou Medical University
Respiratory Failure
Patient-Ventilator Dyssynchrony Detection With a Machine Learning Algorithm
This is a diagnostic study aiming to compare accuracy to detect and classify patient-ventilator dyssynchronies by a machine learning algorithm, compared to the gold-standard defined as dyssynchronies diagnosed and classified by…
- Trial name
- NCT06506123
- Testing
- Artificial Intelligence Detection and Classification of Patient-Ventilator Dyssynchronies
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Sao Paulo General Hospital
Non-small Cell Lung Cancer
The Detection Of Circulating Tumor Cells (CTC) In Patients With NSCLC Undergoing Definitive Radiotherapy Or Chemoradiotherapy
CTC levels collected pre-surgery will be correlated with pathological samples.
- Trial name
- NCT02135679
- Testing
- Radiotherapy
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant
Xpert MTB/XDR Clinical Evaluation Trial
FIND and partners intend to address the need for a multi- and extensively drug-resistant tuberculosis (M/XDR-TB) diagnostic solution for patients in settings with a high burden of drug-resistant tuberculosis (DR-TB) though the…
- Trial name
- NCT03728725
- Testing
- Cepheid Gene Xpert MTB/XDR
- Where
- Moldova
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Hypertension, Pulmonary
A Study for the Identification of Biomarker Signatures for Early Detection of Pulmonary Hypertension (PH)
The primary purpose of this study is to identify and develop biomarker signatures based on circulating micro ribonucleic acid (RNA) in the blood samples associated with high risk of pulmonary hypertension (PH) to assist in the…
- Trial name
- CIPHER (NCT04193046)
- Testing
- Blood Sample
- Where
- 49 sites in United States, Belgium and 7 more
- Volunteers
- 907 people
- Sponsor
- Janssen Research & Development, LLC
Atelectasis Neonatal, Pneumothorax and Air Leak
Detection of Atelectasis or Pneumothorax and Resolution With Electrical Impedance Tomography (EIT) in Newborn Infants
To validate the benefits of recognizing asymmetric lung disease like atelectasis and pneumothorax in neonatal respiratory distress syndrome using electrical impedance tomography
- Trial name
- DePIcT (NCT04848727)
- Testing
- Detecting asymmetric lung disease like atelectasis or pneumothorax with electrical impedance tomography (EIT)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sharp HealthCare
Cystic Fibrosis
Detection of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity in Rectal Tissues From Human Subjects
This is a pilot study. The purpose of the study is to facilitate the development of a new biomarker of cystic fibrosis transmembrane conductance regulator (CFTR) function using rectal tissue.
- Trial name
- NCT01078740
- Where
- 3 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- CF Therapeutics Development Network Coordinating Center
Lung Infection
Detecting Lung Infections Through Vibration
The purpose of this study is to test a lung air vibrator device for vibrating air inside the lung. This exploratory diagnostic trial will test a novel and non-invasive means of detecting lower airway infections using exhaled…
- Trial name
- NCT02056860
- Testing
- Group 1 will receive 15 Hz, Group 2 will receive 30 Hz, Group 3 will receive 60 Hz
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Florida
Acute Lung Injury
Biomarkers in Exhaled Breath Condensates in Acute Lung Injury: Early Detection and Outcome Predictors
Metabolomics, or metabonomics, is a large-scale approach to monitoring as many as possible of the compounds involved in cellular processes in a single assay to derive metabolic profiles.
- Trial name
- NCT01503723
- Testing
- Determined by intended physician
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Asthma, Bronchial
Wheeze Detection in Adults During Dynamic Bronchial Situations Measured by PulmoTrack® 2010 With WIM-PC™ Technologies Recording
The PulmoTrack® 2010 with WIM-PC™ Technologies device, indicated for acoustic pulmonary function measurement that quantifies the presence of wheezing.
- Trial name
- NCT00644462
- Testing
- PulmoTrack® 2010 with WIM-PC™ Technologies
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- KarmelSonix Ltd.
Lung Cancer
A Study to Evaluate Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Lung Malignancies
This Phase 2 study is an open-label, single-arm trial where each patient is his/her own "intrapatient" control. All patients will receive a single dose of pegsitacianine prior to standard of care surgery.
- Trial name
- NCT05048082
- Testing
- pegsitacianine, Tumor resection surgery
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- OncoNano Medicine, Inc.
Lung Cancer, Smoking
Pulmonary Nodule Detection: Comparison of an Ultra Low Dose vs Standard Scan.
Lung cancer screening programs are still discussed in Europe today, and one of the concern is radiation due to iterative CT. The aim of this monocentric, prospective, non randomized study is to compare an ultra low dose chest CT…
- Conditions
- Lung Cancer, Smoking, Radiation Exposure
- Trial name
- npUBD (NCT03305978)
- Testing
- Ultra low dose chest CT, Low dose chest CT
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Grenoble
Chronic Obstructive Pulmonary Disease (COPD), Environmental Exposure
Detection and Characterization of COPD in Dairy Farmers
A pilot study from the investigators group suggests that the prevalence of chronic obstructive pulmonary disease (COPD) among dairy farmers is higher than in the general population.
- Trial name
- BALISTIC (NCT02540408)
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Bronchiolitis Obliterans
Hyperpolarized 129Xe MRI for the Assessment of BOS With Late Onset LONIPC
The development of bronchiolitis obliterans syndrome (BOS) and other late onset non-infectious pulmonary complications (LONIPCs) following hematopoietic stem cell transplantation (HSCT) is associated with a significantly worse…
- Trial name
- BOS-MRI (NCT04029636)
- Testing
- Inhaled Hyperpolarized Xenon-129
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Hamilton Health Sciences Corporation