Clinical trials: Respiratory; Disorder, Functional, Impaired
Mood Disorders, Physical Inactivity
Cardiopulmonary Assesments in Mood Disorders
The importance of cardiorespiratory impact in mental diseases is generally emphasized in studies, but it is noteworthy that cardiorespiratory affects in mood disorders have not been sufficiently investigated.
- Conditions
- Mood Disorders, Physical Inactivity, Respiratory Function Impaired
- Trial name
- NCT06181123
- Testing
- Cardiorespiratory Assesments
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Hematologic Disorder
Lenalidomide as Immune Adjuvant in Patient's With Chronic Lymphocytic Leukemia (CLL)
The goal of this clinical research study is to learn if lenalidomide can increase the level of immunoglobulins (parts of the blood that may help to improve the immune system's function) and/or will improve the protective effect…
- Trial name
- NCT01924169
- Testing
- Lenalidomide, Influenza Vaccine, Pneumovax Vaccine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Unilateral Vocal Cord Paralysis
Establish Quantitative Measurements of Laryngeal Sensorimotor Functions and Evaluating the Grade of Phonation and Swallowing Impairment
Laryngeal motor and sensory nerve dysfunction may cause phonation and swallowing disturbance, which often happens after the treatment for laryngopharyngeal and esophageal cancer and may induce fatal complications such as…
- Trial name
- NCT02243722
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Chang Gung Memorial Hospital
Pain, Postoperative, Analgesic Requirement
Effect of Intraperitoneal and Intravenous Lignocaine on Pain Relief Following Laparoscopic Cholecystectomy
Laparoscopic Cholecystectomy is the treatment of choice for patients with symptomatic gall stones. For pain relief following laparoscopic cholecystectomy both intraperitoneal and intravenous administration of lignocaine has been…
- Conditions
- Pain, Postoperative, Analgesic Requirement, Stress Response, Return of Bowel Activity
- Trial name
- NCT01717222
- Testing
- Intraperitoneal Lignocaine, Intravenous Lignocaine
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Jawaharlal Institute of Postgraduate Medical Education & Research
COPD
Effects of Combined Cognitive Rehabilitation in COPD Patients
This study was to examine the effect of endurance training combined with cognitive training in patients with COPD. The intervention group underwent Cognitive Training added to Endurance Training and the control group underwent…
- Trial name
- NCT03907839
- Testing
- clinical trials
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculty of Medicine, Sousse
COVID-19
A Study to Learn About How Loss of Liver Function Affects the Blood Levels of the Study Medicine Called PF-07817883.
The purpose of the study is to learn about the safety of PF-07817883 and how PF-07817883 is processed in the body of adult participants. These participants will have different degrees of loss of liver function.
- Trial name
- NCT05884554
- Testing
- PF-07817883
- Where
- 6 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Pfizer
Inadequate or Impaired Respiratory Function, Diabetes
Effects of Respiratory Muscle Training in Obese Women
The objective of this study will be to evaluate the effects of inspiratory muscle training (IMT) on the physical fitness of obese women It is believed that the application of these exercises helps in the improvement of…
- Conditions
- Inadequate or Impaired Respiratory Function, Diabetes, Hypertension
- Trial name
- NCT03767556
- Testing
- Inspiratory muscle training
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Renal Impairment
Renal Impairment Study of PF-07321332 Boosted With Ritonavir in Adult Participants With Renal Impairment and in Healthy Participants With Normal Renal Function.
This is a Phase 1, non-randomized, open-label, 2-part study to investigate the effect of renal impairment on the pharmacokinetics (PK), safety and tolerability of a single oral dose of PF-07321332 in combination with the PK…
- Trial name
- NCT04909853
- Testing
- PF-07321332/ritonavir
- Where
- 5 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Pfizer
Stroke, Hemiplegia
Air Stacking-Assisted Diaphragmatic Breathing in Stroke
The purpose of this study is to investigate whether a diaphragmatic breathing exercise using the air stacking technique can improve respiratory function and trunk control in patients with stroke.
- Trial name
- NCT07577076
- Testing
- Air stacking-assisted diaphragmatic breathing, diaphragmatic breathing
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- jang ji-hun
Obstructive Sleep Apnea, Cognitive Impairment
12-week Tele-exercise Program in Patients With OSA
Obstructive sleep apnea (OSA) contributes to a number of adverse health effects, particularly on brain health. Chronic sleep disturbances caused by OSA could adversely affect cognitive health.
- Trial name
- NCT06467682
- Testing
- tele-exercise
- Volunteers
- 60 people
- Sponsor
- University of Cyprus
Muscle Weakness, Syndrome; Institutionalization
Effects and Costs of Respiratory Muscle Training in Institutionalized Elderly People
The global loss of muscle mass and strength associated with aging is a cause of functional impairment and disability, particularly in the older elderly (>80 years).
- Conditions
- Muscle Weakness, Syndrome; Institutionalization, Respiratory Morbidity, Cardiovascular Morbidity
- Trial name
- NCT01759992
- Testing
- Threshold® Inspiratory Muscle Trainer (treatment).
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- University of Valencia
Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE)
Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)
This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on participants living with chronic hypoxic ischemic encephalopathy (HIE) who receive an emerging…
- Conditions
- Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest, Hypoxic Ischemic Encephalopathy of Newborn
- Trial name
- GEN-HOPE (NCT07264166)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Healing Hope International
Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum
Anterior Ethmoidal Nerve Block in Prevention of Postoperative Agitation
Postoperative agitation is an important complication of general anesthesia, moreover, it has been found with high incidence in ear, nose, throat (ENT) surgeries.
- Conditions
- Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum, Chronic Rhinosinusitis (Diagnosis), Nasal Polyps
- Trial name
- NCT03427502
- Testing
- Bupivacaine-epinephrine, normal saline
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Lumbini Medical College
COVID-19 Pneumonia, Impaired Respiratory Function
Study of Efficacy and Safety of DV890 in Patients With COVID-19 Pneumonia
This clinical study was designed to assess the efficacy and safety of DFV890 for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infected patients with coronavirus disease 2019 (COVID-19) pneumonia…
- Trial name
- NCT04382053
- Testing
- DFV890, Standard of Care (SoC)
- Where
- 29 sites in Argentina, Brazil and 10 more
- Volunteers
- 143 people
- Sponsor
- Novartis Pharmaceuticals
Breast Cancer, Sarcoma
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
This is a phase 2a, randomized, double-blinded, placebo-controlled pilot clinical trial determining the impact of riluzole therapy on circulating brain derived neuropathic factor (BDNF) levels in cancer survivors (recently…
- Conditions
- Breast Cancer, Sarcoma, Gastric Cancer, Lung Cancer
- Trial name
- NCT06580002
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, Irvine
Respiratory; Disorder, Functional, Impaired
Dexamethasone and Respiratory Function After Mastectomy
Preoperative dexamethasone reduces symptoms after different surgical procedures including mastectomy in breast cancer, but the effect in the postoperative respiratory function remains unknown.
- Trial name
- Dexa-mama (NCT02305173)
- Testing
- Intravenous Dexamethasone, intravenous salin water
- Where
- Mexico
- Volunteers
- 120 people
- Sponsor
- Instituto Mexicano del Seguro Social
Respiratory; Disorder, Functional, Impaired, Respiratory Infection Other
Wood Smoke Interventions in Native American Populations
A critical need exists for efficient community-based interventions aimed at reduction of environmental exposures relevant to health.
- Trial name
- EldersAIR (NCT02240069)
- Testing
- Education (Tx1), Air Filtration Unit Treatment (Tx2)
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- University of Montana
Breast Cancer, Postoperative Pain
The Effect of Rhomboid Intercostal Block and Serratus Anterior Plane Block on Postoperative Respiratory Functions
Rhomboid intercostal block is used to block lateral cutaneous branches of intercostal nerves between T3 and T9 dermatomes. Serratus anterior plane block is used to block lateral cutaneous branches of intercostal nerves between T2…
- Conditions
- Breast Cancer, Postoperative Pain, Respiratory Function Impaired
- Trial name
- RIBSAB (NCT05547932)
- Testing
- RIB+SAP blocks
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Muğla Sıtkı Koçman University
Chronic Obstructive Pulmonary Disease (COPD)
Sensorimotor Function in COPD
The aim of this study was to investigate the level of sensorimotor function impairment according to disease stage in individuals with Chronic Obstructive Pulmonary Disease (COPD) and to determine whether functional differences…
- Trial name
- NCT07825636
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University