Clinical trials: Respiratory Allergy
Asthma, Hypersensitivity
A Study of Inhalation of 20,000 EU CCRE in Normal Volunteers Compared to Allergic Asthmatic Individuals
This will be a single center, open label study comparing baseline characteristics of recovered sputum cells (collected on screening day) to those of cells recovered 6 hours after inhalational challenge with 20,000 EU Clinical…
- Trial name
- Endomac (NCT00839124)
- Testing
- Clinical Center Reference Endotoxin (CCRE)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Asthma
Efficacy & Safety of Symbicort® TURBUHALER® 160/4.5 µg Twice Daily & Pulmicort® TURBUHALER® 200 µg Twice Daily + Theolong® Tablet 200 mg Twice Daily in Japanese Asthmatic Patients
The primary objective of this study is to confirm the efficacy (superiority) of Symbicort® Turbuhaler® 160/4.5 µg twice daily for 8 weeks in comparison to Pulmicort® Turbuhaler® 200 µg twice daily + Theolong® tablet 200 mg twice…
- Trial name
- NCT00252785
- Testing
- Budesonide/Formoterol, Budesonide, Theophylline
- Where
- 43 sites in Japan
- Volunteers
- 340 people
- Sponsor
- AstraZeneca
Allergic Asthma
Efficacy and Safety Trial of Subcutaneous Immunotherapy in Mite Induced Asthma
The purpose of this study is to determine whether a short course of subcutaneous immunotherapy is efficacious in mite induced asthma. The efficacy is based on reduction in control medication.
- Trial name
- NCT00492076
- Testing
- Pangramin Plus D. pteronyssinus 100%
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- ALK-Abelló A/S
Asthma
Office-Based Asthma Screening Intervention
In prior work, we found that even children who have been seen by their physicians within the prior six months were frequently misclassified as having mild rather than persistent asthma.
- Trial name
- NCT00156468
- Testing
- Provider Prompt
- Where
- United States
- Volunteers
- 365 people
- Sponsor
- University of Rochester
Allergy, Asthma
Allergy and Asthma Following Children Who Were Fed Supplemented Infant Formula
Long-term cognitive outcome study of children who participated in randomized trials of LCP-supplemented formula during infancy.
- Trial name
- NCT00740974
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Rhinitis, Allergic, Perennial
Investigation of Potential Additive Inhibitory Effects on HPA-Axis of Ciclesonide Nasal Spray When Administered Concomitantly With Orally Inhaled Beclomethasone Dipropionate (HFA-BDP) in Patients With Perennial Allergic Rhinitis (PAR) (BY9010/M1-408)
The primary objective of this study is to demonstrate that there are no clinically relevant additive inhibitory effects on the HPA-axis when ciclesonide nasal spray is concomitantly administered with orally inhaled HFA-BDP.
- Trial name
- NCT00659048
- Testing
- Ciclesonide
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- AstraZeneca
Lung Diseases, Asthma
Better Asthma Outcomes: Lowering Tobacco Smoke Exposure
To improve disease outcomes through reduction in secondhand tobacco smoke exposure of children with asthma
- Trial name
- NCT00217958
- Testing
- SHS reduction intervention based on social cognitive learning theory
- Sponsor
- Palo Alto Medical Foundation
Allergic Rhinitis
Efficacy and Safety of Arbidol in the Treatment of Allergic Rhinitis
The most important treatment for AR is topical nasal medications (including nasal corticosteroids, nasal antihistamines, nasal decongestants, and nasal saline irrigation etc.), which are still limited.
- Trial name
- NCT06462417
- Testing
- Arbidol
- Where
- 2 sites in China
- Volunteers
- 15 people
- Sponsor
- Zheng Liu
Asthma
PreAsthmaControl (PAC)
The purpose of this study is to investigate the ability of budesonide, given during episodes of troublesome lung symptoms to reduce further symptoms in infants and young children at risk of developing asthma
- Trial name
- NCT00234390
- Testing
- Pulmicort (budesonide) pMDI
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- AstraZeneca
Asthma
Multisystemic Therapy to Reduce Health Disparities in Adolescents With Asthma
Asthma is a chronic lung disease that inflames and narrows the airways. Symptoms can include recurring periods of wheezing, chest tightness, shortness of breath, and coughing.
- Trial name
- NCT00916240
- Testing
- Multisystemic Therapy, Home-based, Non-Directive Family Support
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma
Study of Safety of CSJ117 in Participants With Moderate to Severe Uncontrolled Asthma
The purpose of this study is to provide safety and tolerability, pharmacokinetics and immunogenicity data for multiple CSJ117 doses inhaled once daily compared with placebo, in adult asthma participants treated with medium or…
- Trial name
- NCT04946318
- Testing
- CSJ117
- Where
- 58 sites in United States, Argentina and 12 more
- Volunteers
- 136 people
- Sponsor
- Novartis Pharmaceuticals
Acute Rhinosinusitis, Allergic Rhinitis
An Observational Study to Evaluate The Relationship of Nasal Mucus Properties and Symptoms
This is a study to learn more about the common cold from studying the nasal secretions produced during a cold or episode of allergic rhinitis.
- Trial name
- NCT01553110
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Virginia Commonwealth University
Asthma
A Pharmacokinetic/Pharmacodynamic Inhaler Comparison Study in Healthy Volunteers
A 2-group healthy volunteer study to compare a breath actuated inhaler (BAI) and a pressurised metered dose inhaler (pMDI) with and without spacer.
- Trial name
- NCT02403713
- Testing
- Fluticasone/formoterol BAI, Formoterol, Fluticasone/formoterol PMDI without spacer
- Where
- United Kingdom
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Mundipharma Research Limited
Asthma
Long-Term Study of IGE025 in Moderate to Severe Bronchial Asthma.
This study will evaluate the safety and efficacy of omalizumab up to 48 weeks in adult patients with moderate to severe bronchial asthma. THIS STUDY IS NOT ENROLLING PATIENTS IN THE UNITED STATES
- Trial name
- NCT00219323
- Testing
- Omalizumab
- Where
- Japan
- Volunteers
- 133 people
- Sponsor
- Novartis
Asthma in Children
Stress and Treatment Response in Puerto Rican Children With Asthma
This study aims to first determine whether high child stress leads to reduced response to common treatmenIs for asthma (inhaled corticosteroids and short-acting bronchodilators), and then to identify DNA methylation differences…
- Trial name
- STAR (NCT03134755)
- Testing
- Inhaled corticosteroid (mometasone)
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 249 people
- Sponsor
- University of Pittsburgh
Allergic Rhinitis
Study of Yupingfeng Powder Treating Allergic Rhinitis (AR)
Rhinitis is broadly defined as inflammation of the nasal mucosa. It is a common disorder that affects up to 40% of the population.
- Trial name
- RCMARb (NCT06608017)
- Testing
- Chinese Herbal Medicine granules
- Where
- Hong Kong
- Volunteers
- 140 people
- Sponsor
- Chinese University of Hong Kong
Asthma
Wessex Asthma Cohort of Difficult Asthma
Asthma is now widely recognised to be a heterogeneous disease. The last two decades have seen the identification of a number of biological targets and development of various novel therapies.
- Trial name
- WATCH (NCT03996590)
- Where
- 3 sites in United Kingdom
- Volunteers
- 566 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Asthma, Obesity
Obesity and Asthma: Nutrigenetic Response to Omega-3 Fatty Acids
This project will assess the effectiveness of omega-3 fatty acid supplementation in controlling asthma symptoms among obese asthmatics, and will assess if a person's genes influence response to treatment (personalized medicine).
- Trial name
- NOOA (NCT01027143)
- Testing
- omega-3 polyunsaturated fatty acids, Omega-3 Fatty Acid
- Where
- 3 sites in United States
- Volunteers
- 143 people
- Sponsor
- Nemours Children's Clinic
Asthma
Analysis of Sexual Bias in Type 2 Innate Lymphoid Cells (ILC2) in Asthmatic Patients
Asthma is more common in females than in males but the difference has not been explained yet. Group 2 innate lymphoid cells (ILC2) have recently emerged as critical players in the initiation of allergic responses but their…
- Trial name
- IL-C2 (NCT04384835)
- Testing
- Blood sample collection (one tube), Blood sample collection (five tubes)
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Toulouse
Hypertension, Diabetes
Development and Testing of a Sub-district Specific Model of 'Whole-of-government', and 'Whole-of-society' Approaches for the Prevention and Control of Non-communicable Diseases in a Sub-district of Bangladesh
Globally, non-communicable diseases (NCDs) are the leading cause of both mortality and morbidity. This intervention study aims to prevent and manage NCDs by adopting the World Health Organization's (WHO) comprehensive…
- Conditions
- Hypertension, Diabetes, Asthma, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT06453382
- Testing
- Behavioural change modification, Screening, NCD related knowledge practice and attitude
- Where
- Bangladesh
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- BRAC University
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