Clinical trials: Respiratory Allergy
Severe Asthma
Register Schweres Asthma - German Asthma Net e.V.
The German Asthma Net e.V. focusses on science and research in patients with severe asthma. This includes, in particular, the optimization of medical care and treatment for patients with severe asthma as well as the elucidation…
- Trial name
- NCT06035289
- Where
- 45 sites in Germany
- Volunteers
- 4,500 people
- Sponsor
- German Asthma Net e.V.
Allergic Asthma, Bronchial Inflammation
Fish Oil and Asthma in House Dust Mite Allergy
Native populations consuming high amounts of fish suffer less from allergic diseases. The purpose of this study is to determine whether polyunsaturated fatty acids (fish oil) might have a disease modifying influence on asthmatics…
- Conditions
- Allergic Asthma, Bronchial Inflammation, House Dust Mite Allergy
- Trial name
- NCT00380926
- Testing
- polyunsatturated fatty acids (fish oil)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Chronic Obstructive Pulmonary Disease, Asthma
Lung Deposition of Beclometasone Dipropionate/Formoterol Fumarate/Glycopyrronium Bromide Administered Via pMDI in Healthy, Asthmatic and COPD Patients
The purpose of this study is to investigate the lung deposition and distribution pattern of Beclometasone dipropionate/Formoterol Fumarate/Glycopyrronium Bromide using a Gamma-scintigraphic technique after inhalation of a single…
- Trial name
- NCT02975843
- Testing
- Beclometasone dipropionate/Formoterol Fumarate/Glycopyrronium
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Hypersensitivity, Hay Fever
Immunological Analysis of Lymph Node Tissue After Intralymphatic Immunotherapy: A Prospective Case Control Study
Allergy is a public health problem as more than 20% of western society is affected by it. Symptomatic treatment of allergy suffices with less severe allergy.
- Conditions
- Hypersensitivity, Hay Fever, Rhinitis, Allergic, Seasonal, Rhinoconjunctivitis
- Trial name
- ILIT-FNA (NCT05960266)
- Testing
- Polvac Grass+Rye
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University of Zurich
Asthma, Wheezing
Pulmonary Epithelium, Immunology and Development of Asthma: Breathing Together
The investigators want to know why some babies wheeze and some of these go on to develop asthma. The investigators are going to find out if babies who develop wheeze and asthma have abnormal airway lining cells (taken from the…
- Trial name
- NCT04063631
- Where
- United Kingdom
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Asthma Exacerbation, Quality of Life
Application of Telehealth Technology in Asthma Management
Background: While effective treatments are available, asthma control is sub-optimal for many asthma patients. To help patients self-manage their asthma symptoms, provision of an asthma action plan (AAP) in written format (wAAP)…
- Conditions
- Asthma Exacerbation, Quality of Life, Medication Adherence
- Trial name
- NCT05484037
- Testing
- CANATEXTS
- Where
- 3 sites in Canada
- Volunteers
- 620 people
- Sponsor
- University of British Columbia
Post-nasal Drip, Seasonal Allergic Rhinitis
Desloratadine With Oxybutynin for the Treatment of Seasonal Allergic Rhinitis and Post-Nasal Drip (Study P04258)(COMPLETED)
This was a 1-week study of desloratadine (DL) plus oxybutynin (OXY) at two dose levels in the treatment of post-nasal drip in participants with seasonal allergic rhinitis.
- Conditions
- Post-nasal Drip, Seasonal Allergic Rhinitis, Rhinorrhea
- Trial name
- NCT00816972
- Testing
- Desloratadine 2.5 mg, Oxybutynin 2.5 mg
- Volunteers
- 540 people
- Sponsor
- Organon and Co
Asthma
Study Evaluating the Effects of AIR645 on Allergen-Induced Airway Responses in Subjects With Mild Atopic Asthma
To assess the efficacy of inhaled AIR645 in the suppression of the Asthmatic Responses in subjects with mild asthma inhaling an allergen.
- Trial name
- NCT00941577
- Testing
- AIR645, Physiologic saline solution
- Where
- 3 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Altair Therapeutics, Inc.
Asthma
Efficacy and Safety of QGE031versus Placebo and Omalizumab in Patients Aged 18-75 Years With Asthma
This study assessed the effect on asthma control of different dose levels and regimens of QGE031 in asthma patients that are inadequately controlled with inhaled steroid and beta-2 agonist medication. Safety was assessed also.
- Trial name
- NCT01716754
- Testing
- QGE031, Omalizumab
- Where
- 150 sites in United States, Argentina and 22 more
- Volunteers
- 471 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
Fluticasone/Salmeterol (FP/SM) Versus Double the Dose Fluticasone (FP) in Patients With Mild to Moderate Asthma
The purpose of this study is to compare the effects of Fluticasone/ salmeterol combination and double the dose of fluticasone on airway hyper-responsiveness to methacholine in a randomised, double blind, double dummy, cross-over…
- Trial name
- CLE001 (NCT00830505)
- Testing
- fluticasone/salmeterol, fluticasone
- Where
- United Kingdom
- Volunteers
- 38 people
- Sponsor
- University of Dundee
Asthma
Montelukast Post-Marketing Comparative Study With Ketotifen (0476-379)
The clinical study evaluates the safety of montelukast and compares montelukast to ketotifen, used as a control drug, in terms of improvement in morning peak expiratory flow (am pef) over first 2 weeks in patients with pediatric…
- Trial name
- NCT00446056
- Testing
- MK0476, montelukast sodium / Duration of Treatment: 4 Weeks, Comparator: ketotifen / Duration of Treatment: 4 Weeks
- Volunteers
- 188 people
- Sponsor
- Organon and Co
Bronchial Asthma
Long-term Study of Safety and Efficacy of Roflumilast in Japanese Patients With Bronchial Asthma (20 to 71 y) (APTA-2217-07).
The aim of this long-term study is to investigate the effect of roflumilast (APTA-2217) on the long-term safety in patients with asthma, who completed the 24-week evaluation of study APTA-2217-05.
- Trial name
- NCT00246922
- Testing
- Roflumilast
- Where
- Japan
- Volunteers
- 150 people
- Sponsor
- AstraZeneca
Asthma
Efficacy and Safety Study of Budesonide Novolizer Dry Powder Inhaler 200μg to Treat Chinese Patients With Mild to Moderate Asthma
This is an open-label, randomized, parallel Group, multicenter study to evaluate the efficacy and safety of budesonide novolizer dry powder inhaler compared with budesonide turbuhaler dry powder inhaler in Chinese mild to…
- Trial name
- NCT01269437
- Testing
- Budesonide dry powder inhaler
- Where
- 11 sites in China
- Volunteers
- 332 people
- Sponsor
- NovaMed Pharmaceuticals Inc.
Allergy, Eczema
Melbourne Infant Study - Bacille Calmette Guérin (BCG) for Allergy & Infection Reduction
1. To determine if BCG immunisation at birth, compared to no BCG immunisation, leads to a reduction in measures of allergy and infection in the first 12 months of life. 2.
- Conditions
- Allergy, Eczema, Respiratory Tract Infections
- Trial name
- MIS BAIR (NCT01906853)
- Testing
- BCG
- Where
- 2 sites in Australia
- Volunteers
- 1,272 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Seasonal Allergic Rhinitis
Bepotastine Besilate Nasal Sprays in the Treatment of Seasonal Allergic Rhinitis (SAR)
This study will examine dose ranging characteristics of bepotastine besilate nasal spray compared to placebo nasal spray in 600 male or female subjects 12 years of age and older with active seasonal allergic rhinitis (SAR) and a…
- Trial name
- NCT01753739
- Testing
- Bepotastine besilate
- Where
- United States
- Volunteers
- 617 people
- Sponsor
- Bausch & Lomb Incorporated
Asthma
Research in Severe Asthma (RISA) Trial
The purpose of this study is to evaluate the safety and efficacy of the Alair System for the treatment of severe refractory asthma.
- Trial name
- NCT00214539
- Testing
- Bronchial Thermoplasty with the Alair System, Control
- Volunteers
- 34 people
- Sponsor
- Boston Scientific Corporation
Allergic Bronchopulmonary Aspergillosis, Asthma
Allergic Bronchopulmonary Aspergillosis Prescreening Study
This prescreening study is being conducted to diagnose ABPA in selected patients with asthma and to increase the potential number of eligible participants for the ongoing Study 601-0018 of PUR1900 in subjects with ABPA.
- Conditions
- Allergic Bronchopulmonary Aspergillosis, Asthma, ABPA
- Trial name
- NCT05903612
- Where
- United Kingdom
- Sponsor
- Community Pharmacology Services Ltd
Asthma
An Observational Study to Investigate How Patients Experience the Ability to Adjust Their Asthma Maintenance Medication
An observational study to investigate how patients experience the ability to adjust their asthma maintenance medication according to instructions received from their physician.
- Trial name
- INVOLVE (NCT00577265)
- Volunteers
- healthy volunteers welcome
- Sponsor
- AstraZeneca
Asthma
Telemedicine Enhanced Asthma Management Through the Emergency Department
In the US, children from minority ethnic and racial backgrounds suffer disproportionately from asthma and account for substantially more emergency department (ED) visits and hospitalizations than non-minority children.
- Trial name
- TEAM-ED (NCT02752165)
- Testing
- TEAM-ED, Enhanced Usual Care
- Where
- United States
- Volunteers
- 384 people
- Sponsor
- University of Rochester
Sleep Apnea, Obstructive, Asthma, Exercise-Induced
Pulmonary Disorders During Exercise in Patients With Obstructive Sleep Apnea
Purposes: 1. To investigate whether patients with severe obstructive sleep apnea syndrome (OSAS) are at higher risk for exercised-induced bronchoconstriction (EIB) due to baseline airway inflammation compared with age, gender…
- Trial name
- NCT00916773
- Testing
- continuous positive airway pressure (CPAP)
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
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