Clinical trials: Respiratory Allergy
Asthma in Children, Exercise Induced Asthma
The Rainbow Study - the Effect of Feedback on Asthmatic Symptom Perception
Asthma is a common childhood disease that is characterized by chronic airway inflammation and episodic expiratory airflow obstruction.
- Trial name
- NCT06702735
- Testing
- Rainbow tool, Feedback
- Where
- Netherlands
- Volunteers
- 39 people
- Sponsor
- Medisch Spectrum Twente
Chronic Rhinitis
A Study of RhinAer Stylus for Treating Chronic Rhinitis
Post-market study to continue to evaluate the effectiveness of the RhinAer Stylus for chronic rhinitis and the effect of treatment on inflammatory biomarkers.
- Trial name
- BIOKLEAR (NCT06599736)
- Testing
- RhinAer Stylus
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Aerin Medical
Asthma
Comparative Effectiveness of a Breath-operated Albuterol Inhaler in Asthma Patients With Poor Inhaler Technique
This study was designed to examine the effectiveness of a breath-operated albuterol inhaler in asthma patients who have difficulty using their standard "press-and-breathe" inhaler.
- Trial name
- NCT00054964
- Testing
- Albuterol HFA-BOI, Albuterol HFA-MDI
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Asthma
To Confirm Equivalent Bronchodilator Efficacy of the Test Product Compared to the Reference Product
The purpose of this study is to confirm equivalent bronchodilator efficacy of the test product compared to the reference product.
- Trial name
- BUFODIL (NCT02308098)
- Testing
- Budesonide/Formoterol Easyhaler 320/9 ug/inhalation 4 inh, Budesonide/Formoterol Easyhaler 320/9 ug/inhalation 1 inh, Symbicort Turbuhaler 320/9 ug/inhalation 4 inh
- Where
- Bulgaria
- Volunteers
- 72 people
- Sponsor
- Orion Corporation, Orion Pharma
Asthma, Common Cold
Effects of Pleconaril Nasal Spray on Common Cold Symptoms and Asthma Exacerbations Following Rhinovirus Exposure (Study P04295)
This is a randomized, multi-center, double-blind, placebo-controlled study evaluating the efficacy of pleconaril nasal spray in preventing asthma exacerbation and common cold symptoms in asthmatic participants exposed to…
- Conditions
- Asthma, Common Cold, Picornavirus Infection, Rhinovirus
- Trial name
- NCT00394914
- Testing
- Pleconaril
- Volunteers
- 311 people
- Sponsor
- Merck Sharp & Dohme LLC
Rhinovirus, RSV Infection
Impact of the Covid-19 on RSV
The magnitude of seasonal RSV epidemics brings each year new logistical challenges for the hospitalization of young infants with bronchiolitis that overwhelm hospital capacities and lead to specific winter plans with…
- Trial name
- IPCoVRS-2 (NCT05348616)
- Testing
- epidemiology
- Where
- 2 sites in France
- Volunteers
- 600 people
- Sponsor
- Hospices Civils de Lyon
Allergic Rhinitis, Allergic Conjunctivitis
The Effects of Ectoin® Allergy Nasal Spray and Ectoin® Allergy Eye Drops Compared to Placebo
The primary objective of this study is to assess the relative efficacy of Ectoin® Allergy Eye Drops and Ectoine® Allergy Nasal Spray compared to placebo, by evaluating Total Nasal Symptom Score (TNSS) and Total Ocular Symptom…
- Trial name
- PPL-003 (NCT01471184)
- Testing
- Ectoin® Allergy Nasal Spray and Ectoin® Allergy Eye Drops
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Bitop AG
Pulmonary Sarcoidosis
Antibody Response to Influenza Vaccine in Patients With Sarcoidosis
The purpose of this study is to determine the efficacy of influenza vaccine (antibody response) in patients with sarcoidosis.
- Trial name
- IVS (NCT00828828)
- Testing
- Influenza Vaccine
- Where
- Iran
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Asthma, Breast Cancer
Collaborative Self-Management Support in Chronic Conditions - Qualitative Study
The management of chronic conditions is a challenge for health systems worldwide, particularly in the context of an aging population, and requires urgent improvement of health services.
- Conditions
- Asthma, Breast Cancer, Stroke
- Trial name
- CoSMaS-ql (NCT03262428)
- Testing
- Semi-structured interviews
- Where
- France
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Sarcoidosis, SARS-CoV2 Infection
Immune Response to SARS-CoV-2/COVID-19 Vaccination in Sarcoidosis
People with sarcoidosis, particularly those with significant lung and/or cardiac involvement, who become infected with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) are likely at increased risk of complications or…
- Conditions
- Sarcoidosis, SARS-CoV2 Infection, Vaccine Response Impaired
- Trial name
- NCT05089565
- Testing
- Assay of (1) the level of anti-spike IgG antibody, and (2) interferon-gamma release in response to SARS-CoV-2 antigen stimulation
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Respiratory Failure, Status Epilepticus
Pilot Simulation RCT of Telemedical Support for Paramedics
This study evaluates the impact of video communication via telemedicine on the quality of emergency care provided to children by paramedic teams supported by a remote physician in a simulated out-of-hospital setting.
- Conditions
- Respiratory Failure, Status Epilepticus, Status Asthmaticus, Cardiopulmonary Arrest
- Trial name
- NCT03742167
- Testing
- Telemedicine
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Boston Medical Center
Asthma
Stimulation of the Cervical Sympathetic Ganglion for Treatment of Asthma
The purpose of this study is to evaluate if stimulating the nerve involved with airway constriction, while undergoing procedures that are known to cause asthma exacerbations, decreases the level of asthma attack experienced.
- Trial name
- NCT01724307
- Testing
- Neurostimulation of stellate ganglion
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Jonathan Parsons
Allergic Bronchopulmonary Aspergilloses
A Study Evaluating Vitamin D in Allergic Bronchopulmonary Aspergillosis Complicating Asthma
Allergic bronchopulmonary aspergillosis (ABPA) is a immunological pulmonary disorder caused by hypersensitive reaction to spores of Aspergillus fumigatus.
- Trial name
- NCT03133299
- Testing
- Glucocorticoids, Vitamin D
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Rhinitis, Allergic, Seasonal, Asthma
Randomized, Placebo Controlled, Crossover Study in an Environmental Challenge Chamber to Assess Safety & Efficacy of Three Oral Doses of BI 671800 Versus Fluticasone Propionate and Montelukast in Sensitive Seasonal Allergic Rhinitis Patients Out of Season
The objective of the current study is to investigate the efficacy, safety and tolerability of BI 671800 ED using three dose levels of BI 671800 ED (50 mg, 200 mg and 400 mg), administered twice daily compared to FP (fluticasone…
- Trial name
- NCT01007721
- Testing
- BI 67100 ED 25 mg, BI 671800 ED 100 mg
- Where
- Germany
- Volunteers
- 146 people
- Sponsor
- Boehringer Ingelheim
Wegener Granulomatosis, Microscopic Polyangiitis
Vasculitis Illness Perception (VIP) Study
The purpose of this study is to learn about how patients with vasculitis think about their illness and to assess to what extent patient perceptions of illness are associated with physical, mental, and social functioning
- Conditions
- Wegener Granulomatosis, Microscopic Polyangiitis, Churg-Strauss Syndrome, Polyarteritis Nodosa
- Trial name
- NCT02190916
- Where
- United States
- Volunteers
- 707 people
- Sponsor
- University of South Florida
Lung Diseases, Medication Compliance
Uncontrolled Lower Respiratory Symptoms in the WTC Survivor Program
The purpose of this study is to understand why patients in the World Trade Center program have continuing breathing problems. This study will improve investigators understanding of breathing problems among individuals with World…
- Trial name
- NCT02024204
- Testing
- Fluticasone propionate 230mcg for 3 Months, Current Treatment or no treatment, Salmeterol 21mcg for 3 Months
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Asthma
Alternate Nostril Breathing With Incentive Spirometry on Lung Function Among Asthma Patients
To compare effects of Alternate Nostril Breathing exercise with incentive spirometer on lung functions (forced vital capacity, forced expiratory volume, and peak expiratory flow rate) in Asthma patients.
- Trial name
- NCT07110116
- Testing
- Alternate nostril breathing with Incentive Spirometery, Incentive spirometery
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Rhinitis
Effectiveness of Individualized Homeopathic Treatment in Perennial Allergic Rhinitis
A total of 41 adults with perennial allergic rhinitis were enrolled in a first double-blind placebo-controlled phase for six months, and treated on a weekly basis with sublingual doses of single individualized homeopathic…
- Trial name
- NCT00822406
- Testing
- homeopathic medicine
- Volunteers
- 41 people
- Sponsor
- University of Sao Paulo
Lung Cancer, Lymphoma
Improving Genomic Profiling and Reducing Time to Cancer Treatment Via Targeted Use of Endoscopic Ultrasound
Aim: To investigate whether the novel 3rd generation FNB needle provides a better diagnostic accuracy than a standard FNA needle in EUS-B guided diagnosis of common deep seated thoracic malignancies (lung cancer and lymphoma).
- Conditions
- Lung Cancer, Lymphoma, Sarcoidosis
- Trial name
- IMPROVED (NCT06848738)
- Testing
- FNB, FNA
- Where
- 3 sites in Denmark
- Volunteers
- 362 people
- Sponsor
- Zealand University Hospital
Asthma
An ADME Study of [14C]AZD4604 and the Absolute Bioavailability of AZD4604
The Sponsor is developing the test medicine, AZD4604, as a potential treatment for asthma. Asthma is a common lung condition caused by inflammation (swelling) of the breathing tubes that carry air in and out of the lungs, causing…
- Trial name
- NCT06157255
- Testing
- AZD4604 Inhalation Powder, 1 mg, [14C]AZD4604 Solution for Infusion 6 μg/mL (NMT 37.0 kBq/5 mL), [14C]AZD4604 Oral Solution, 4 mg (NMT 37.0 kBq)
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
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