Clinical trials: Respiratory Allergy
Seasonal Allergic Rhinitis
Effect of a Probiotic on Seasonal Allergic Rhinitis Symptoms
The purpose of the current study is to evaluate the efficacy of administering a probiotic in adult human subjects suffering from allergic rhinitis during seasonal grass pollen exposure.
- Trial name
- NCT01653652
- Testing
- Probiotic, Maltodextrin
- Where
- Germany
- Volunteers
- 131 people
- Sponsor
- Société des Produits Nestlé (SPN)
Asthma
Albuterol DPI (A006) Clinical Study-B3:Efficacy, Dose-ranging and Safety Evaluation
This study evaluates the efficacy, dose-ranging and safety profiles of A006, an Albuterol dry powder inhaler (DPI), in the dose range of 110 to 220 mcg per dose in comparison to a DPI Placebo Control and an Albuterol metered dose…
- Trial name
- A006-B3 (NCT02210806)
- Testing
- A006 DPI, Proventil® MDI
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Asthma
A Computerized Asthma Management System in the Pediatric Emergency Department
The primary goal of this study is that the combination of a computerized asthma reminder system with implementation of an guideline will increase utilization and adherence of guideline-driven care, leading to improved patient…
- Trial name
- NCT01070147
- Testing
- Computerized Asthma Management System
- Where
- United States
- Volunteers
- 1,631 people
- Sponsor
- Vanderbilt University Medical Center
Asthma
Non-Interventional Study to Describe the Clinical Management in Asthmatic Patients (NICMA)
Asthma is a heterogenic chronic disease that affects more than 300 million people worldwide, which it's characterized by acute symptomatic episodes of varying severity, including intermittently inflammation and narrowing of the…
- Trial name
- (NICMA) (NCT06811155)
- Where
- Spain
- Volunteers
- 288 people
- Sponsor
- Hospital Universitario Virgen de la Victoria
Asthma, Electrophilic Fatty Acids
Electrophilic Fatty Acid Derivatives in Asthma
Asthma is an inflammatory disease, which means it causes swelling in the lungs to cause shortness of breath and/or wheezing. There are several asthma medications that help to reduce this problem.
- Trial name
- EFADA (NCT01733485)
- Testing
- Aspirin, Indomethacin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Sally E. Wenzel MD
COVID-19
Effect Of Calcitriol On Neutrophil To Lymphocytes Ratio And High Sensitivity C-Reactive Protein Covid-19 Patients
This research is a study that compares the administration of calcitriol with the outcomes of COVID-19 patients
- Trial name
- NCT05765617
- Testing
- Calcitriol
- Where
- Indonesia
- Volunteers
- 16 people
- Sponsor
- Universitas Sebelas Maret
Asthma
A Comparison of Mometasone Furoate DPI Versus Budesonide DPI in Budesonide DPI in Asthmatics (Study P04880)
This study will be an open-label, parallel-group comparison of Mometasone Furoate Dry Powder Inhaler (MF-DPI) 200 mcg once daily in the evening with two puffs vs.
- Trial name
- NCT00442117
- Testing
- mometasone furoate dry powder inhaler, Budesonide DPI
- Volunteers
- 180 people
- Sponsor
- Organon and Co
Chronic Respiratory Diseases
Intestinal Microbiota in COPD and Asthma
The composition of the intestinal microbiota, the level of lipopolysaccharides, TMAO in the blood, and other parameters of patients with COPD (n=50), asthma (n=50) and the control (n=40) will be assessed as factors associated…
- Trial name
- MicrObAs (NCT04802317)
- Testing
- Identification of the composition of the intestinal microbiota
- Where
- Russia
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Asthma
A Study to Compare the Efficacy of Fluticasone Furoate/Vilanterol Inhalation Powder With Usual Inhaled Corticosteroids (ICS)/Long Acting Beta Agonists (LABA) in Persistent Asthma
The combination of FF, an ICS and VI, an orally inhaled LABA has been developed as a once-daily combination therapy for the long-term maintenance treatment of asthma in adults and children >=12 years of age.
- Trial name
- NCT02446418
- Testing
- Fluticasone Furoate, Vilanterol, Fluticasone propionate
- Where
- 93 sites in France, Germany
- Volunteers
- 423 people
- Sponsor
- GlaxoSmithKline
Asthma
Pneumococcal Vaccines in Patients With Asthma
Investigators are assessing if patients with asthma respond better to the Pneumovax vaccine if they are given Prevnar initially.
- Trial name
- NCT03260790
- Testing
- PCV13, PPSV23
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Mayo Clinic
Asthma
The Role of Vitamins E and C in Maintaining Lung Health in People With Asthma
This study will determine if airway antioxidant levels in allergic asthmatics are enhanced with a combination of vitamin E and vitamin C therapy.
- Trial name
- VITAS (NCT00142610)
- Testing
- Vitamin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of North Carolina, Chapel Hill
Obstructive Sleep Apnea, Coronary Heart Disease
Long-term Effects of CPAP on Lipidemia and Hs-CRP Levels in OSA Patients
The increased risk of atherosclerotic morbidity and mortality in patients with obstructive sleep apnea (OSA) has been linked to hypertension, insulin resistance, dyslipidemia, and systemic inflammation.
- Trial name
- NCT02127177
- Testing
- Continuous Positive Airway Pressure Ventilator
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Asthma
Dose Response of Fractional Exhaled Nitric Oxide (FeNO) to Inhaled Steroids in Mild-to-moderate Asthma
Asthma is a chronic disease, which means that it cannot be cured, but the investigators can use inhalers and tablets to control the symptoms.
- Trial name
- NCT00995657
- Testing
- Fluticasone Propionate
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University of Dundee
Allergy
Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of QGE031 in Japanese Atopic Male Subjects
This study will evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of QGE031 in Japanese atopic male subjects in order to determine the eligibility of Japanese patients in subsequent clinical…
- Trial name
- NCT01596712
- Testing
- QGE031
- Where
- Japan
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Perennial Allergic Rhinitis
Children, Perennial Allergic Rhinitis (PAR), l-t Growth
The purpose of this study is to compare the effect of Rhinocort nasal spray with placebo on growth in children with perennial allergic rhinitis over 12 months.
- Trial name
- NCT00641212
- Testing
- Budesonide
- Volunteers
- 209 people
- Sponsor
- AstraZeneca
Asthma, Severe Persistent Asthma
Implications and Stability of Clinical and Molecular Phenotypes of Severe Asthma
The Severe Asthma Research Program III is an NIH cooperative agreement involving 7 clinical centers that encompass a multidisciplinary partnerships between asthma clinician-scientists and scientists with expertise in immunology…
- Trial name
- SARPIII (NCT01748175)
- Testing
- Triamcinolone Acetonide
- Where
- United States
- Volunteers
- 715 people, healthy volunteers welcome
- Sponsor
- Sally E. Wenzel MD
Asthma, Major Depressive Disorder
Treating Caregiver Depression to Improve Childhood Asthma: Impact and Mediators
The investigators propose a one-year, repeated measures, within-subject design to examine the impact of improved caregiver depression on child asthma outcomes.
- Trial name
- NCT02809677
- Testing
- Non-Interventional
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- University of Texas Southwestern Medical Center
Asthma
Acupoint Massage Combined With Ear Point Pressing Beans
Objective: To explore the application effect of acupoint massage combined with ear point pressing beans in the remission stage of asthma.
- Trial name
- NCT06650917
- Testing
- the experiment group were treated acupoint massage combined with ear point pressing beans, the control group were treated with acupoint massage
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hai'an Hospital of TCM001
Asthma, Chronic Obstructive Pulmonary Disease
Usability and Acceptability Study of the P-STEP Mobile Application
Assess the usability and acceptance of the P-STEP app, through allowing participants with specific chronic conditions to pilot the app for 12-weeks.
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease, Coronary Heart Disease
- Trial name
- NCT05830318
- Testing
- P-STEP Mobile Application
- Where
- United Kingdom
- Volunteers
- 178 people
- Sponsor
- University of Leicester
Asthma, Allergic Rhinitis
Assessment of Oxidative Stress Markers in the Upper and Lower Airways of Atopic Children Treated With Nebulized Beclomethasone
Although it is well known that the presence of uncontrolled inflammation in upper airways may compromise the control of asthma and may favor the progression of asthma toward more severe grades of disease, few studies addressed…
- Trial name
- NCT01113489
- Testing
- beclomethasone dipropionate
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Fondazione C.N.R./Regione Toscana "G. Monasterio", Pisa, Italy
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