Clinical trials: Respiratory Allergy
Asthma
A Double Blind Open Label Comparator Study to Compare Treatments in 4 to 11 Year Old Patients With Asthma
The purpose of the study is to characterize the pharmacokinetic profiles of fluticasone propionate and/or salmeterol when delivered as a single oral inhalation dose of Fp MDPI and FS MDPI.
- Trial name
- NCT02680561
- Testing
- Fluticasone Propionate MDPI, Fluticasone Propionate/Salmeterol MDPI, Fluticasone propionate/salmeterol
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Asthma (Diagnosis)
Effects of Wet Cupping Therapy in Patients With Asthma
This study evaluated the effects of wet cupping therapy on immune modulation, pulmonary function, and quality of life in adults with asthma.
- Trial name
- WCT-ASTHMA (NCT07764042)
- Testing
- Wet Cupping Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Medipol University
Asthma
Impact of Aerobic Exercise on Asthma Morbidity
Asthma is a chronic disorder of the airways primarily driven by increased airway inflammation, and is an escalating medical problem in Canada.
- Trial name
- Ex-Asthma (NCT00953342)
- Testing
- Aerobic exercise, Usual care
- Where
- 3 sites in Canada
- Volunteers
- 66 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Asthma
Implementation of Evidence-based Breathing Retraining for Patients With Asthma in Region Zealand
This study aims to implement the evidence-based intervention breathing retraining into clinical care of patients with symptomatic asthma irrespective of asthma severity or comorbidities, and in a diverse multicentre setting to…
- Trial name
- EmBRAiZ (NCT05531370)
- Testing
- Breathing Retraining
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Naestved Hospital
Asthma, Cough
Mannitol-Induced Cough Challenge in Healthy Controls and Subjects With Mild Allergic Asthma
The study aim is to investigate if changes in osmolarity using mannitol challenge can evoke coughing reproducibly in mild allergic asthmatics compared with healthy controls and if salbutamol can affect this.
- Trial name
- MICC (NCT03620422)
- Testing
- Mannitol, Salbutamol 5mg/mL, Sodium Chloride 0.9% Inhl 3Ml
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- McMaster University
Allergic Rhinitis With Asthma
Efficacy and Safety of Yiqi Wenyang Sanhan Formula Combined With Acupoint Application in Patients With Combined Allergic Rhinitis and Asthma Syndrome During Remission and Yang-Deficiency Syndrome
Allergic rhinitis-asthma syndrome is a clinical comorbid condition involving both upper and lower airway allergic inflammation, reflecting the concept of "one airway, one inflammatory response." Epidemiological studies have…
- Trial name
- NCT07540351
- Testing
- Yiqi Wenyang Sanhan Formula Combined with Acupoint Application
- Volunteers
- 188 people
- Sponsor
- Beijing Daxing District Hospital of Integrated Chinese and Western Medicine
Asthma
Bioequivalence Study to Compare Fluticasone Furoate (FF) 1-strip Inhaler With FF 2-strip Inhaler and With FF/Vilanterol Combination
The purpose of this study is to determine the bioequivalence of fluticasone furoate (FF) inhalation powder (single strip configuration) compared with FF inhalation powder (two strip configuration) and compared with FF /…
- Trial name
- NCT01485445
- Testing
- Fluticasone Furoate (200mcg unit strength), Fluticasone Furoate/Vilanterol (200/25mcg unit strength)
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Asthma in Children, Lung Function Decreased
Lung Function Variability in Children and Adolescents
Long-term variability analysis of peak expiratory flow (PEF) and forced expiratory volume in 1 s (FEV1) has been successfully used in research to predict the exacerbation of the disease in adult individuals with asthma.
- Trial name
- LUV (NCT04163146)
- Testing
- Measurements of PEF and FEV1
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Patras
Exercise Induced Asthma
Trial on the Effect of Budesonide/Formoterol and Inhaled Budesonide Alone on Exercise-Induced Asthma
The purpose of this study is to find out if Symbicort® (budesonide/formoterol), a new combination asthma medication, is more effective than budesonide alone in controlling exercise induced asthma.
- Trial name
- NCT01070888
- Testing
- Budesonide/Formoterol, Budesonide
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Boston Children's Hospital
Asthma Bronchiale, COPD
Bronchodilator Response in COPD and Asthma: Correlation Between Spirometry, IOS Indices, and Dyspnea Relief
A bronchodilator reversibility test is widely used in the diagnosis and management of obstructive lung diseases. Bronchodilators relieve symptoms in asthma and COPD.
- Conditions
- Asthma Bronchiale, COPD, Bronchodilation, Spirometry
- Trial name
- NCT07364188
- Testing
- Bronchodilator
- Volunteers
- 120 people
- Sponsor
- Allergi- og Lungeklinikken, Elsinore
Asthma
Environmental Mycobiota: In-depth Characterisation and Determinants Involved in Asthma Emission
The analysis of the exposome of severe asthmatic patients and its correlation with the response profile to biotherapies used in the treatment of severe asthma and/or the frequency of exacerbations, could make it possible to…
- Trial name
- MyCADO (NCT05789927)
- Testing
- Assessment of the microbial exposome
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Bordeaux
Asthma, Lung Diseases
Comparison of Two Medication Adherence Strategies to Improve Asthma Treatment Adherence
This is a randomized, controlled study that will compare two medication adherence strategies in adults with moderate or severe persistent asthma as a method for improving or maintaining treatment adherence.
- Trial name
- NCT00115323
- Testing
- Problem Solving, Attention Control
- Where
- United States
- Volunteers
- 397 people
- Sponsor
- University of Pennsylvania
Asthma, Eczema
Bacille Calmette-Guérin (BCG) Vaccine and Atopy
The prevalence of asthma and allergic diseases is increasing worldwide. Infections and vaccinations in childhood may have an impact on the subsequent development of asthma and allergy.
- Conditions
- Asthma, Eczema, Food Hypersensitivity
- Trial name
- NCT01420705
- Where
- Guinea-Bissau
- Volunteers
- 487 people
- Sponsor
- Bandim Health Project
Asthma
A Single-Dose Study of MK-8351 in a Lung Allergen Challenge (MK-8351-003)
The primary hypothesis of the study is single doses of MK-8351 will reduce the baseline early asthmatic response (EAR) as assessed by area under the curve from 0-3 hours (AUC0-3hr) of forced expiratory volume (FEV1) when compared…
- Trial name
- NCT01926002
- Testing
- Low-Dose MK-8351, High-Dose MK-8351
- Sponsor
- Merck Sharp & Dohme LLC
Asthma
New Version Pulmicort Turbuhaler USA Children
A comparison of the safety, efficacy and budesonide pharmacokinetics of the currently approved Pulmicort Turbuhaler with a new version of the inhaler, in children and adolescents who have asthma.
- Trial name
- NCT00642161
- Testing
- budesonide
- Volunteers
- 430 people
- Sponsor
- AstraZeneca
Asthma
A Study to Evaluate the Effectiveness and Safety of MEDI-528 in Adults
To study the effectiveness and safety of multiple-doses of MEDI-528 on asthma control in adult participants with uncontrolled, moderate-to-severe, persistent asthma.
- Trial name
- NCT00968669
- Testing
- MEDI528 30 mg, MEDI528 100 mg, MEDI528 300 mg
- Where
- 57 sites in United States, Argentina and 8 more
- Volunteers
- 329 people
- Sponsor
- MedImmune LLC
ASTHMA
Risk Factors Associated to Difficult-to-control Asthma
Several studies have demonstrated the efficacy of asthma treatment but despite being correctly diagnosed, conveniently prescribed and adherent to the therapeutics, 5% to 10% of asthmatics do not reach disease control.
- Trial name
- NCT01089322
- Testing
- inhaled corticosteroid plus LABA plus oral corticosteroid
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Rafael Stelmach
T Cell Response to Asthma in HIV-infected Patients Before and After Starting Treatment
Children With HIV and Asthma (CHIVAS)
To explore allergen-specific effector and regulatory T cell response in HIV-infected children before and after HAART initiation
- Trial name
- NCT01644370
- Testing
- HAART
- Where
- 2 sites in Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration
Asthma
Validity and Reliability of the 6-minute Stepper Test in Patients With Asthma
Asthma is a chronic respiratory disease that can negatively affect exercise tolerance and functional capacity due to airway inflammation, variable airflow limitation, and symptom-related activity avoidance.
- Trial name
- NCT07357805
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Gazi University
Bronchial Asthma
Pulmicort Respules 0.25/0.5 Specific Clinical Experience Investigation
The purpose of this study is to investigate the safety and efficacy for long term treatment of the drug in children aged 6 months and < 5 years on bronchial asthma in daily clinical usage.
- Trial name
- NCT01232322
- Volunteers
- 633 people
- Sponsor
- AstraZeneca
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.