Clinical trials: Respiratory Compliance
Cystic Fibrosis, Patient Engagement
Cystic Fibrosis Reproductive and Sexual Health Collaborative: Building Online Research Partnerships
This is a Patient-Centered Outcomes Research Institute engagement effort aimed at training researchers/providers and patients to work in research teams together online throughout the research process (including: development…
- Trial name
- NCT04999865
- Testing
- 4-part educational program to build patient-engagement methodology capacity
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Lung Cancer
Effect of Optimal Positive End-Expiratory Pressure on Oxygenation and Intrapulmonary Shunt During One-lung Ventilation
To observe the effect of compliance guided an optimal Positive End-Expiratory Pressure（PEEP）on arterial oxygenation and intrapulmonary shunt during one-lung ventilation(OLV)，and discuss the lung protective effect of optimal PEEP…
- Trial name
- NCT03804398
- Testing
- compliance guided an optimal Positive End-Expiratory Pressure, PEEP level of 5 cmH2O
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Fujian Medical University Union Hospital
Asthma, Telemedicine
Impact of the Implementation of a Telemedicine Program on Patients Diagnosed with Asthma
Introduction: Asthma is one of the most common chronic respiratory diseases worldwide. Despite the extensive knowledge of the condition and available therapeutic options, severe asthmatic patients have poor disease control in 50%…
- Conditions
- Asthma, Telemedicine, Adherence, Treatment, Quality of Life
- Trial name
- NCT06116292
- Testing
- The mobile application ESTOI for Asthmatic patients
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Hospital Universitari de Bellvitge
Tuberculosis, Pulmonary, Medication Adherence
Evaluating Urine Isoniazid Testing to Detect Nonadherence to Tuberculosis Medications in India
Tuberculosis (TB) is the leading infectious cause of death globally. India has the largest TB epidemic, accounting for one-quarter of cases and one-third of TB deaths worldwide.
- Trial name
- NCT06526221
- Testing
- Urine isoniazid testing (IsoScreen test)
- Where
- 2 sites in India
- Volunteers
- 900 people
- Sponsor
- Tufts University
Personality, Patient Compliance
Distribution of Mood and Personality Characteristics and Their Influence on Treatment Compliance
This study intends to investigate the personality and psychological characteristics of OSA patients using classical standard scales and obtain treatment information and adherence data through prospective follow-up to summarize…
- Conditions
- Personality, Patient Compliance, Anxiety, Depression
- Trial name
- NCT07101796
- Testing
- continous positive airway pressure (CPAP)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Vaccine Refusal, COVID-19
Exploring the Effect of Video Interventions on Intentions for Continued COVID-19 Vaccination
While COVID-19 vaccine uptake has generally been high in Canada, with 83.4% of the total population having received the first two doses (i.e., primary series), additional "booster" uptake has been slower, especially among young…
- Trial name
- NCT05808413
- Testing
- Informational Video, Altruistic Video, Individualistic Video
- Where
- Canada
- Volunteers
- 3,567 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Asthma
A Computer-Based ED Intervention to Improve Pediatric Asthma Medicine Adherence
Asthma is common in children and impacts their health. There are effective medications for improving asthma, but some families have difficulty using medicines on a regular basis.
- Trial name
- ED-AMAP (NCT02787174)
- Testing
- Asthma Medication Adherence Education
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Rhode Island Hospital
Sleep Apnea Syndromes
Improving Obstructive Sleep Apnea Management Via Wireless Telemonitoring
Obstructive sleep apnea (OSA) is a major chronic condition affecting the quality of life of up to one-fifth of all Veterans. Because of disappointingly low adherence to the gold-standard treatment (continuous positive airway…
- Trial name
- NCT00682838
- Testing
- Self-management, Telemonitored care
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- VA Office of Research and Development
Sore Throat, Dysphagia
Chewing Gum and Cold Gargle on Post-Bronchoscopy Symptoms
This study aims to evaluate the effects of chewing gum and gargling with cold water on common post-bronchoscopy symptoms, such as sore throat and difficulty swallowing (dysphagia).
- Conditions
- Sore Throat, Dysphagia, Patient Satisfaction, Bronchoscopy
- Trial name
- NCT07517926
- Testing
- Chewing Gum, Cold Water Gargle
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Ankara University
Immunization; Infection, Influenza
Seasonal Influenza and Pneumococcal Vaccination in the Elderly
The elderly population and individuals with chronic diseases are at high risk for influenza and influenza-related pneumonia, and it is emphasized that taking pneumonia and influenza vaccine together is effective in reducing…
- Conditions
- Immunization; Infection, Influenza, Pneumonia, Vaccine Refusal
- Trial name
- NCT05661890
- Where
- Turkey (Türkiye)
- Volunteers
- 1,166 people
- Sponsor
- Lokman Hekim University
Asthma
Parent-Youth Teamwork in Pediatric Asthma Management
The purpose of this research study is to examine the effectiveness of a parent-youth teamwork treatment and an asthma education treatment in helping children use their asthma medicines correctly.
- Trial name
- NCT00166582
- Testing
- electronic medication monitoring system, parent-adolescent communication and problem-solving skills
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Intra-Abdominal Hypertension, Respiratory Mechanics
Intra-Abdominal Pressure, Respiratory Mechanics, and Ventilator Liberation After Emergency Major Laparotomy
This prospective observational cohort study aims to investigate the relationship between intra-abdominal pressure (IAP), respiratory system mechanics, and successful liberation from invasive mechanical ventilation in adult…
- Conditions
- Intra-Abdominal Hypertension, Respiratory Mechanics, Mechanical Ventilation
- Trial name
- IAP-VENT (NCT07889609)
- Testing
- Serial Intra-Abdominal Pressure and Respiratory Mechanics Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Chronic Obstructive Pulmonary Disease, Adherence, Treatment
Role of Inhaler Adherence and Blood Eosinophil Count in Exacerbations of COPD
This is an observational study examining inhaler adherence and subsequent changes in blood eosinophil count in exacerbations of Chronic obstructive pulmonary disease (COPD) population.
- Trial name
- INCLINE (NCT05814484)
- Where
- United Kingdom
- Volunteers
- 104 people
- Sponsor
- University of Leicester
Vaccination Hesitancy
Mobile Health-based Motivational Interviewing to Promote COVID-19 Vaccination
The objective of this study is to evaluate the preliminary efficacy and acceptability of an mobile Health-based motivational interviewing (MI) intervention to promote SARS-CoV-2 vaccination (MOTIVACC) compared to traditional…
- Trial name
- COVID-19 (NCT05977192)
- Testing
- Standard MI, Intensive MI, MOTIVACC
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Sore Throat, Tonsillitis
The BLIS Study: a Feasibility Study Assessing Compliance, Acceptability and Colonisation With Different Dosing Regimens of the Probiotic Supplement Streptococcus Salivarius K12 (Bactoblis®) in Adults
Short title The BLIS study Full title A feasibility study assessing compliance, acceptability and colonisation with different dosing regimens of the probiotic supplement Streptococcus salivarius K12 (Bactoblis®) in adults…
- Conditions
- Sore Throat, Tonsillitis, Pharyngitis
- Trial name
- NCT04297878
- Testing
- probiotic supplement Streptococcus salivarius K12 (Bactoblis®)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Pulmonary Disease, Chronic Obstructive
Influence Of Salmeterol Xinafoate/Fluticasone Propionate (50/500 µg BID) On The Course Of The Disease And Exacerbation Frequency In COPD Patients Gold Stage III And IV
This is a 12 month randomized, open-label, parallel-group study to obtain data on the frequency and variability of exacerbations in severe and very severe Chronic Obstructive Pulmonary Disease (COPD) patients (Global Initiative…
- Trial name
- NCT00527826
- Testing
- Salmeterol / Fluticasone (50/500 µg) BID fixed combination, Salmeterol / Fluticasone (50/500 µg) BID separate Inhalers
- Where
- 23 sites in Germany
- Volunteers
- 214 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis
Impact of RYALTRIS® Nasal Spray on Patients' Reported Outcomes
A real world evidence study that aims to understand the impact of RYALTRIS® nasal spray in patients with Allergic Rhinitis over a 28-day period.
- Trial name
- NCT05129306
- Testing
- Observational
- Where
- Australia
- Sponsor
- Community and Patient Preference Research Pty Ltd
Chronic Obstructive Pulmonary Disease
Long-term Effects of Non-invasive Ventilation in Hypercapnic Chronic Obstructive Pulmonary Disease (COPD) Patients
In this multicenter study the comparison of the mass flow distribution and redistribution versus the relative blood flow per lobe (as a surrogate for Ventilation/ Perfusion (V/Q) matching) with functional respiratory imaging…
- Trial name
- NCT01592656
- Testing
- Functional Respiratory Imaging, Lung compliance measurement, Non-invasive ventilation (Respironics)
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 40 people
- Sponsor
- FLUIDDA nv
Health Education, COVID-19, Quarantine, Anxiety, Pandemic
The Effectiveness of a Health Education Intervention to Reduce Anxiety in Quarantined COVID-19 Patients
we aimed to assess the impact of health education on the anxiety level of COVID-19 patients during the isolation period.
- Trial name
- NCT05715593
- Testing
- health education intervention
- Where
- Tunisia
- Volunteers
- 402 people
- Sponsor
- University of Monastir
Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Rehabilitation
Factors Associated With Acceptance of Home-Based Pulmonary Telerehabilitation in COPD
Pulmonary rehabilitation improves symptoms, exercise capacity, and quality of life in people with chronic obstructive pulmonary disease (COPD), but access and participation may be limited by travel, organizational, logistical…
- Trial name
- ACCEPT-TR (NCT07747571)
- Testing
- No intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- ADIR Association