Clinical trials: Respiratory Compliance
Childhood Asthma
Asthma Link: A Real World Application of School Supervised Asthma Therapy
The goal of this study is to assess the feasibility of a clinical trial to evaluate the impact and process of deploying school-supervised asthma therapy in a real-world setting for children with poorly controlled asthma (aged…
- Trial name
- NCT04942379
- Testing
- Asthma Link, Enhanced Usual Care
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Massachusetts, Worcester
COVID-19, Vaccine Hesitancy
COVID-19 Vaccine Hesitancy Among Nurses
The purpose of this study is to investigate the correlation of intention to receive COVID-19 vaccine, recommendation behavior, and 5C psychological antecedents among Nurses.
- Conditions
- COVID-19, Vaccine Hesitancy, Vaccination, Nurses
- Trial name
- NCT05212974
- Testing
- Questionnaires
- Where
- Taiwan
- Volunteers
- 4,258 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Inhalation, Respiratory Disease
Inhalation Therapy and Therapeutic Play
The aim of this clinical research study was to determine the effect of the use of a cartoon character mask on treatment compliance and parental satisfaction and to evaluate the effectiveness of the cartoon character mask in…
- Trial name
- INHALATION (NCT06197646)
- Testing
- Cartoon characters inhaler mask
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istinye University
Airway Obstruction, Sedation Complication
Evaluation of Medical Device for Airway Patency During Sedation (SW01-2022)
The goal of this four-part preclinical [I-II] and clinical [III-IV] trial is to compare, with randomised crossover study design [I-IV], a new medical airway device with standard procedure (biteblock or no device) for upper airway…
- Conditions
- Airway Obstruction, Sedation Complication, Safety Issues, Patient Satisfaction
- Trial name
- NCT05708651
- Testing
- Investigational device [I-IV], Comparator [I-IV]
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Stairway Medical AB
Respiratory Distress Syndrome
Comparison in Pulmonary Compliance Between Curosurf and Survanta in Preterm Infants With Respiratory Distress Syndrome
This is a null hypothesis study. The investigators hypothesize that there will be no difference in changes in dynamic compliance when measured at 15, 30, 45 and 60 minute intervals after administration of either surfactant and…
- Trial name
- NCT01537354
- Testing
- Curosurf®, Survanta®
- Where
- United States
- Sponsor
- University of Michigan
OSAHS
Self-Reported Versus Objective Measured Compliance With Oral Appliance Therapy for Obstructive Sleep Apnea Hypopnea Syndrome
Oral appliances, such as Mandibular Repositioning Appliances (MRA), have emerged as a treatment option for sleep-disordered breathing (SDB).
- Trial name
- NCT01284881
- Testing
- MRA
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Hospital, Antwerp
Anesthesia, Postoperative Complications
Evaluation of V/Q Mismatch as Predictor of Pulmonary Postoperative Complications in Patients Undergoing Major Surgery
Pulmonary postoperative complications (PPC) are among the main causes of surgical complications affecting both postoperative morbidity and mortality.
- Conditions
- Anesthesia, Postoperative Complications, Mechanical Ventilation Complication
- Trial name
- VQppc (NCT05454917)
- Testing
- Measure of ventilation/perfusion (V/Q) mismatch using Beacon ALPE (Automatic Lung Paramether Estimator)
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- Università degli Studi di Ferrara
Pulmonary Resection Surgery, One Lung Ventillation (OLV)
BMI-Adjusted PEEP During One-Lung Ventilation in Thoracic Surgery
One-lung ventilation (OLV) is required during many thoracic surgical procedures and is associated with reduced functional residual capacity, atelectasis, ventilation-perfusion mismatch, hypoxemia, and potentially…
- Conditions
- Pulmonary Resection Surgery, One Lung Ventillation (OLV), General Anesthetic
- Trial name
- SIMPLE-PEEP (NCT07851740)
- Testing
- Fixed PEEP, BMI-adjusted PEEP
- Where
- 4 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Jesús Manuel Nieves Alonso
Laparoscopic Surgery, Pneumoperitoneum
Role of Individualized PEEP Vs Fixed PEEP in Mechanical Ventilation During Laparoscopic Surgeries
To compare the effects of Individualized positive end-expiratory pressure with recruitment maneuver on respiratory parameters and oxygenation in mechanical ventilation during laparoscopic surgeries with the fixed positive…
- Conditions
- Laparoscopic Surgery, Pneumoperitoneum, Positive End Expiratory Pressure (PEEP)
- Trial name
- NCT06929078
- Testing
- Protective lung ventilation methods with different positive end-expiratory pressure during Laparoscopic Surgeries
- Where
- Pakistan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Noor-Ul-Ain
Cognitive Function, Well-Being
Singing Groups for Seniors: Well-Being, Cognitive Function and Health
The researchers' implement and measure the effects of a singing group intervention program for older adults, with an RCT design, in a natural context, on the health, well-being and cognitive function of older adults.
- Conditions
- Cognitive Function, Well-Being, Physical Function, Respiratory Function
- Trial name
- Sing4Health (NCT03985917)
- Testing
- Singing Group Intervention Program, Alternative Social and Leisure Activities
- Where
- Portugal
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Iolanda Costa Galinha
Vaccine Uptake
Boosting COVID-19 Vaccination Uptake Using Wastewater Surveillance
Vaccinations are among the most successful and critical public health interventions. Despite the enormous protection that vaccines provide to public health, both delays and refusals of vaccines (vaccine hesitancy) are on the…
- Trial name
- NCT06698497
- Testing
- Communication Campaign
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Obstructive Sleep Apnea
RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA
The goal of this randomised, double-blind phase II/III clinical trial is to determine the safety and efficacy of IHL-42X in subjects with obstructive sleep apnoea who are intolerant, non-compliant, or naïve to positive airway…
- Trial name
- REPOSA (NCT06146101)
- Testing
- IHL-42X Low Dose, IHL-42X High Dose, IHL-42X (Optimal Dose)
- Where
- 20 sites in United States
- Volunteers
- 121 people
- Sponsor
- Incannex Healthcare Ltd
Chronic Obstructive Pulmonary Disease (COPD)
Readmissions to Hospital Among Patients With COPD After Telemedicine Video Consultation - a Pilot Project
The purpose of this study was to evaluate the effects of telemedicine video-consultation (TVC) on the frequency of hospital re-admissions during 12 months follow-up after TVC among patients with chronic obstructive pulmonary…
- Trial name
- NCT02006082
- Testing
- Telemedicine video-consultation (TVC)
- Where
- Norway
- Volunteers
- 99 people
- Sponsor
- Helse Stavanger HF
Obstructive Sleep Apnea
PAP Adherence After Diet/Lifestyle Intervention in OSA Patients
The aim of this study is to explore the role of diet/lifestyle intervention on Positive airway pressure (PAP) treatment adherence in patients with obstructive sleep apnea (OSA).Specifically, we evaluated the effects of a…
- Trial name
- NCT05881824
- Testing
- MDG intervention
- Where
- Greece
- Volunteers
- 74 people
- Sponsor
- University of Crete
Chronic Obstructive Pulmonary Disease (COPD)
Validation of Questionnaire and Assessment of Patient Satisfaction for Budesonide/Formoterol Fix Combination Dry Powder Inhalers (DPI) in Chronic Obstructive Pulmonary Disease (COPD)
The aim of this study is to describe patient preferences on budesonide/formoterol fix dose combination for the treatment of their COPD, and to find those factors more strongly associated to a better attitude to medication.
- Trial name
- NCT01646424
- Where
- 20 sites in Turkey (Türkiye)
- Volunteers
- 446 people
- Sponsor
- AstraZeneca
SARS-CoV-2 Infection
EuGeni Rapid Antigen Test for the Qualitative Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Causing COVID19 Disease in Compliance With the World Health Organization (WHO)
Rapid antigen detection (RAD) tests are used to perform rapid diagnosis of SARS-CoV-2 infection based on a qualitative approach.
- Trial name
- WHO (NCT05618561)
- Testing
- EuGeni SARS-CoV-2 Antigen Rapid Diagnostic Test
- Where
- 5 sites in Croatia, Greece and 1 more
- Volunteers
- 599 people, healthy volunteers welcome
- Sponsor
- AnteoTech Ltd
Ventilator Adverse Event, Ventilator Associated Pneumonia
Effect of Angulus on Patient-elevation Compliance
Ventilator-associated events (VAE) are a scourge of critical care settings and hospital systems at large. There is extensive evidence that ventilator-associated pneumonia (VAP) and related VAEs increase mortality rates in…
- Conditions
- Ventilator Adverse Event, Ventilator Associated Pneumonia, Hospital Acquired Condition, Hospital-acquired Pneumonia
- Trial name
- NCT03496220
- Testing
- Angulus
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Angulus, LLC
Stress Disorders, Post-Traumatic, Stress Related Disorder
Mindfulness-SOS: Stress Reduction for Refugees
The COVID-19 pandemic crisis is associated with a wide range of stressors for the general population. For forcibly displaced persons (FDPs), the turmoil of this crisis is magnified significantly, and elevated pre-existing…
- Trial name
- NCT04761510
- Testing
- Mindfulness-SOS for Refugees
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Haifa
COVID-19 Infection
Evaluation of an Interactive Risk Information Tool to Increase COVID-19 Vaccination Incidence in Vaccine-hesitant People
Coronavirus (COVID-19) vaccines have saved millions of lives since release and remain a key tool in the fight against the pandemic.
- Trial name
- iWILL (NCT05193903)
- Testing
- Simulation, Text
- Where
- Germany
- Volunteers
- 1,188 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Respiratory Disease
A Pilot Study to Assess the Suitability of the HealthBeacon Injection Care Management System (ICMS) as a Remote Therapeutic Monitoring (RTM) Device
This goal of this study is to assess the suitability of the HealthBeacon Injection Care Management System (ICMS) as a Remote Therapeutic Monitoring (RTM) device for patients on injectable medications in the home-setting, for the…
- Trial name
- NCT05592769
- Testing
- HealthBeacon Injection Care Management System (ICMS)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- HealthBeacon Plc