Clinical trials: Respiratory Compliance, active
Asthma, Nonadherence, Medication
Symptom-driven ICS/LABA Therapy for Patients With Asthma Non-adherent to Daily Maintenance Inhalers
Inhaler nonadherence is a common problem that has been estimated to account for approximately 60% of all asthma-related hospitalizations.
- Trial name
- NCT05111262
- Testing
- Adherence to symptom driven budesonide/formoterol as compared to adherence to maintenance ICS and symptom-driven SABA
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine
Bronchopulmonary Dysplasia, Pulmonary Hypertension Due to Lung Diseases and Hypoxia
Ventilator Pressure and Optimization of Compliance and Hemodynamics
In preterm infants < 34 weeks' gestation at birth receiving respiratory support with invasive positive pressure ventilation, the positive end-expiratory pressure (PEEP) of best compliance will increase the cardiac output and…
- Conditions
- Bronchopulmonary Dysplasia, Pulmonary Hypertension Due to Lung Diseases and Hypoxia, Extreme Prematurity, Ventilator Lung; Newborn
- Trial name
- VPOCH (NCT06512935)
- Testing
- Increase in the PEEP followed by decrease in the PEEP, Decrease in the PEEP followed by increase in the PEEP
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Alabama at Birmingham
Cystic Fibrosis, Cystic Fibrosis Liver Disease
Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER)
RECOVER is a prospective, multicenter observational study designed to measure the real world clinical effectiveness of elexacaftor/tezacaftor/ivacaftor (ETI) triple combination therapy in people with cystic fibrosis initially…
- Conditions
- Cystic Fibrosis, Cystic Fibrosis Liver Disease, Cystic Fibrosis in Children, Adherence, Medication
- Trial name
- RECOVER (NCT04602468)
- Testing
- Elexacaftor/Tezacaftor/Ivacaftor
- Where
- 7 sites in Ireland, United Kingdom
- Volunteers
- 206 people
- Sponsor
- Royal College of Surgeons, Ireland
Cardio-vascular Disease, Depression Disorders
Supporting Patients Starting New Medicines: Evaluating the myCare Start Service in Switzerland
In Phase B, the aim is to evaluate the myCare Start service in routine care within the ambulatory primary care medicine and community pharmacy setting in Switzerland.
- Conditions
- Cardio-vascular Disease, Depression Disorders, Diabetes, COPD
- Trial name
- myCare Start-I (NCT07036471)
- Testing
- myCare Start
- Where
- Switzerland
- Volunteers
- 1,600 people
- Sponsor
- University of Geneva, Switzerland
Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH), Pulmonary Arterial Hypertension (PAH)
imprOving Adherence to Pulmonary artErial hyperteNsion Treatment With teLemedicIne and patieNt guidaNce
Pulmonary arterial hypertension (PAH) is a progressive condition with high morbidity, frequent hospitalizations, and risk of right heart failure. Despite advances in treatment, poor adherence remains a major challenge.
- Conditions
- Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH), Pulmonary Arterial Hypertension (PAH), Pulmonary Arterial Hypertension
- Trial name
- OPENLINE (NCT06850792)
- Testing
- Telemedicine-Based Adherence Support
- Where
- Brazil
- Volunteers
- 61 people
- Sponsor
- University of Sao Paulo General Hospital
Screening Compliance, Lung Cancer (Diagnosis)
Increasing Lung Cancer Screening Uptake Among Emergency Department Patients
The objective of the proposed clinical trial is to determine if we can increase LCS among ED patients using a combination of facilitated referral to an LCS program plus text message reminders to get screened.
- Conditions
- Screening Compliance, Lung Cancer (Diagnosis), Lung Cancer Diagnosis, Lung Cancer
- Trial name
- NCT07287085
- Testing
- Facilitated referral and text messaging, Basic Referral (enhanced control arm)
- Where
- United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Lung Cancer
Scale of Therapeutic Adherence to Respiratory Rahabilitation for Lung Cancer
The goal of this non experimental, transversal instrument study is to Construct and determine the reliability and validity of the Scale of Therapeutic Adherence for Respiratory Rehabilitation in Lung Cancer in Mexican patients…
- Trial name
- STA-RR-LC (NCT06477302)
- Testing
- Scale of Therapeutic Adherence to Respiratory Rahabilitation for Lung Cancer (STA-RR-LC)
- Where
- Mexico
- Volunteers
- 281 people
- Sponsor
- Instituto Nacional de Cancerologia de Mexico
Sleep Apnea, Obstructive
Long-term Efficacy, Tolerance and Compliance of Panthera D-SAD® Mandibular Advancement Orthosis in Sleep Apnea
Obstructive sleep apnea (OSA) is a common, chronic and serious medical condition. Oral appliance therapy (OAT) also called mandibular advancement orthosis (MAO) provides long-term therapy for OSA patients.
- Trial name
- PANTHERA (NCT05461417)
- Testing
- D-SAD
- Where
- France
- Volunteers
- 337 people
- Sponsor
- Panthera Dental Inc.
Pulmonary Tuberculosis, Treatment Adherence
Effectiveness of Psychosocial Counseling in Patients With a New Tuberculosis Diagnosis
Introduction: Newly diagnosed TB patients frequently experience psychological distress, stigma, and concerns regarding treatment duration, side effects, and social consequences, which may negatively affect adherence.
- Conditions
- Pulmonary Tuberculosis, Treatment Adherence, Mental Health
- Trial name
- NCT07703696
- Testing
- psychosocial counseling
- Where
- Indonesia
- Volunteers
- 108 people
- Sponsor
- Universitas Diponegoro
Acute Respiratory Distress Syndrome ARDS
Driving Pressure-guided Tidal Volume Ventilation in the Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) is associated with high mortality, some of which can be attributed to ventilator-induced lung injury (VILI) when artificial ventilation is not customized to the severity of lung injury.
- Trial name
- DRIVENT (NCT06322758)
- Testing
- Tidal volume customization in the acute respiratory distress syndrome
- Volunteers
- 750 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obstructive Sleep Apnea, Coronary Disease
Patients with Coronary Artery Disease or At High Cardiovascular Risk: Measuring Compliance with Treatment for Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea (OSA) is a sleep disorder characterised by partial or total obstruction of the oro-pharyngeal carrefour during sleep.
- Conditions
- Obstructive Sleep Apnea, Coronary Disease, Cardiovascular Diseases
- Trial name
- PACOAM (NCT06568159)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Obesity &Amp; Overweight, Hypertension
A Prospective Randomnised Controlled Trial Comparing Overall Patient Compliance in a Bariatric Surgical Pathway Using the Standard Versus a More Intensified and Interactive Version of the "Get Ready" Smartphone Application.
The aim of this study is to assess the impact of a newly intensified digital platform following bariatric surgery. This will be measured using several questionnaires.
- Conditions
- Obesity &Amp; Overweight, Hypertension, Obstructive Sleep Apnea (OSAS), Diabetes Mellitus ( Type 1 and Type 2)
- Trial name
- NCT07297342
- Testing
- GetReady application, Intensified GetReady application
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Sint Dimpna Ziekenhuis Geel
Asthma in Children, Intellectual Disabilities (F70-F79)
Smart Inhaler and Remote Asthma Management in Adolescents With Intellectual and Developmental Disabilities
Correct use of daily medications containing inhaled corticosteroids is key for asthma control, yet children with intellectual and developmental disabilities (IDD) face additional barriers to proper inhaler use.
- Conditions
- Asthma in Children, Intellectual Disabilities (F70-F79), Developmental Disability, Autism Spectrum Disorder
- Trial name
- IDD (NCT07746921)
- Testing
- Use of active remote smart inhaler in the home setting, Use of passive remote smart inhaler in the home setting
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Children's Hospital Los Angeles
Medication Adherence, Quality of Life
ECHO-COPD: Impact of a Pharmacist-Led Health Belief Model-Based Educational Intervention Among Chronic Obstructive Pulmonary Disease Patients
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease associated with substantial morbidity and mortality, impaired quality of life, and healthcare costs.
- Conditions
- Medication Adherence, Quality of Life, Cost, Health Belief Model
- Trial name
- ECHO-COPD (NCT07815353)
- Testing
- Pharmacist-Led HBM-Based Educational Intervention
- Where
- Saudi Arabia
- Volunteers
- 140 people
- Sponsor
- Rabia Hussain
Healthy Participants
Educational VR Game Intervention to Enhance Hygiene Practices in Primary School Children
The goal of this observational study is to investigate if VR game-based educational intervention can enhance primary schoolchildren's compliance with hygiene practices to prevent the transmission of SARS-CoV-2 and other upper…
- Trial name
- NCT07168759
- Testing
- VR game -based education program
- Where
- China
- Volunteers
- 2,160 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Head and Neck Cancers, Laryngeal Carcinoma
Telemedicine Follow-Up for Early Laryngeal Cancer: a Randomized Controlled Trial Comparing Care Close to Home Versus Standard of Care
The goal of this clinical trial is to evaluate whether Telemedicine follow-up is a satisfactory and safe alternative to traditional follow-up care for patients treated for early glottic (vocal cord) cancer, particularly those who…
- Trial name
- Telemedicine (NCT06940505)
- Testing
- Telemedicine Follow-up
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- University Medical Center Groningen
Obstructive Sleep Apnea
Exploring the Use of Phototherapy to Improve CPAP Compliance
Photobiomodulation (PBM) is a type of light therapy like lasers and LEDs. PBM was previously known by different terms like "low-level laser therapy" (LLLT) or "photobiostimulation." LLLT, despite its name, can also have effects…
- Trial name
- NCT06960161
- Testing
- Phototherapy
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Lung Cancer, Quality of Life
Improvement of Quality of Life (QoL) Using Preference-Oriented QoLMonitoring in Patients with Lung Cancer
The purpose of the study is to determine whether a preference-oriented quality of life monitoring with defined diagnostic and therapeutic options improves quality of life in patients with lung cancer during routine follow-up care.
- Trial name
- LePaLuMo (NCT06252233)
- Testing
- patient- and physician-centered QoL monitoring
- Where
- 8 sites in Germany
- Volunteers
- 220 people
- Sponsor
- University of Bayreuth
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis
We are studying the effect of a mind-body treatment for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with or without Long COVID (LC).
- Trial name
- MILES (NCT06933173)
- Testing
- Dynamic neural retraining system
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of Alberta
Tuberculosis, Pulmonary, Medication Adherence
Evaluating Urine Isoniazid Testing to Detect Nonadherence to Tuberculosis Medications in India
Tuberculosis (TB) is the leading infectious cause of death globally. India has the largest TB epidemic, accounting for one-quarter of cases and one-third of TB deaths worldwide.
- Trial name
- NCT06526221
- Testing
- Urine isoniazid testing (IsoScreen test)
- Where
- 2 sites in India
- Volunteers
- 900 people
- Sponsor
- Tufts University