Clinical trials: Respiratory Distress Neonatal
Respiratory Distress Syndrome
Nasal Intermittent Positive Pressure Ventilation In Newborn Infants With Respiratory Distress Syndrome
The submitted trial is the first prospective, randomized trial comparing nasal intermittent positive pressure ventilation(NIPPV) vs nCPAP in newborn infants with respiratory distress syndrome.
- Trial name
- NCT00780624
- Testing
- NIPPV
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Third Military Medical University
Respiratory Distress Syndrome In Premature Infants
Successful Extubation and Noninvasive Ventilation in Preterm ≤ 1500g Terms
Noninvasive ventilation has been used in preterm newborn with respiratory distress syndrome in an attempt to assist failure extubation.
- Trial name
- NCT02396693
- Testing
- NIPPV, Bubble NCPAP, Ventilator NCPAP
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Neonatal Respiratory Distress Related Conditions, Neonatal Respiratory Failure
Automated Versus Manual Control Of Oxygen For Preterm Infants On Continuous Positive Airway Pressure In Nigeria
One in ten babies are born preterm (<37 weeks gestation) globally. Complications of prematurity are the leading cause of death in children under 5 years, with the highest mortality rate in Sub-Saharan Africa (SSA).
- Conditions
- Neonatal Respiratory Distress Related Conditions, Neonatal Respiratory Failure, Prematurity, Oxygen Toxicity
- Trial name
- NCT05508308
- Testing
- OxyMate, Manual oxygen control
- Where
- 2 sites in Nigeria
- Volunteers
- 49 people
- Sponsor
- Murdoch Childrens Research Institute
Cystic Fibrosis
HFN Versus NIV in Cystic Fibrosis. The HIFEN Study
Many patients with cystic fibrosis (CF) require hospitalization and/or Intensive Care Unit (ICU) admission because of acute exacerbation of chronic respiratory failure or for any acute deterioration of clinical status.
- Trial name
- NCT02262871
- Testing
- High flow nasal oxygen cannula, Noninvasive ventilation
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Unity Health Toronto
Prematurity, Respiratory Distress Syndrome
Trial of Non Invasive Ventilation for Respiratoy Distress Syndrome
The purpose of this study is to evaluate the hypothesis that nasal intermittent positive pressure(NIPP), used as a primary mode of ventilation in preterm infants with RDS, will decrease the need for conventional endotracheal…
- Trial name
- NCT00821119
- Testing
- nasal intermittent positive pressure ventilation
- Where
- 2 sites in Brazil
- Volunteers
- 200 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Acute Respiratory Distress Syndrome
Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress Syndrome
A randomized, concurrent controlled trial to assess if adding sigh breaths to usual invasive mechanical ventilation of victims of trauma who are at risk of developing ARDS will decrease the number of days they require invasive…
- Trial name
- SiVent (NCT02582957)
- Testing
- Sigh breaths
- Where
- 15 sites in United States
- Volunteers
- 524 people
- Sponsor
- University of Minnesota
Prematurity, Respiratory Distress Syndrome
Autologous Umbilical Cord Blood Transfusion for Preterm Neonates
This is a pilot study to test feasibility of collection, preparation and infusion of a baby's own (autologous) umbilical cord blood in the first 14 days after birth if the baby is born premature <35 weeks of gestation.
- Conditions
- Prematurity, Respiratory Distress Syndrome, Anemia of Prematurity, Intraventricular Hemorrhage
- Trial name
- NCT01121328
- Testing
- Autologous cord blood transfusion for preterm neonates, Autologous cord blood transfusion
- Where
- Egypt
- Sponsor
- Sahar M.A. Hassanein, MD
Prematurity, Respiratory Distress Syndrome
Comparing Different Delivery Systems of Continuous Positive Airway Pressure in Neonates
The goal of this clinical trial is to compare late preterm newborn lung physiology when supported with different continuous positive airway pressure (CPAP) devices.
- Trial name
- NCT06038565
- Testing
- RAM cannula ventilator CPAP, Occlusive interface bubble CPAP
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Neonatal Respiratory Distress, Preterm Birth
Study of the Feasibility of Early Lung Ultrasound in Neonatal Respiratory Distress in Premature Newborns Born Between 32 Weeks of Amenorrhea and 36 Weeks Plus 6 Days of Amenorrhea, Hospitalized in the Neonatal Pediatrics and Intensive Care Units of the Dijon University Hospital
Monocentric study carried out in the Neonatal and Intensive Care Units of the Dijon University Hospital. The objective is to evaluate the feasibility of performing a pulmonary ultrasound within 6 hours after admission in…
- Trial name
- REchoPP (NCT05737095)
- Testing
- Pulmonary ultrasound
- Where
- France
- Volunteers
- 69 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Respiratory Distress Syndrome in Premature Infant, Surfactant Deficiency Syndrome Neonatal
Feasibility Study - Neofact
For therapy of respiratory distress syndrome (RDS) in premature babies, there are several established options. An important therapeutic aspect is the tracheal administration of exogenous surfactant into the child's lung.
- Trial name
- NCT04086095
- Testing
- Neofact application aid
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Tuebingen
Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
Pilot Trial of Surfactant Booster Prophylaxis For Ventilated Preterm Neonates
A research study that will evaluate if giving surfactant medication to premature babies weighing < 1250 gm at birth during the second and third weeks of life will help their lungs.
- Trial name
- NCT00208039
- Testing
- Infasurf
- Volunteers
- 89 people
- Sponsor
- Children's Hospital of Philadelphia
Neonatal Respiratory Distress Syndrome
Heated, Humidified High-flow Nasal (HHHFN) Cannula vs Nasal Continuous Positive Airway Pressure in Respiratory Distress in Premature Neonates
Newborn babies who have difficulty breathing may need breathing support to help them receive enough oxygen. Two commonly used methods are heated, humidified high-flow nasal cannula (HHFNC), which delivers warmed, moist air and…
- Trial name
- NCT07891494
- Testing
- Heated Humidified High-Flow Nasal Cannula therapy, nCPAP
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Neonatal Respiratory Distress
Vaginal Misoprostol to Improve the Neonatal Respiratory Outcome
Project summary: Objective: To test the hypothesis that administration of vaginal Misoprostol before elective cesarean section will improve the neonatal respiratory outcomes in late preterm and early term neonates through…
- Trial name
- NCT03239327
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 292 people
- Sponsor
- Assiut University
Respiratory Distress Syndrome
Facilitated Tucking Position During Endotracheal Suctioning
Aim of the present study The present study will aimed to determine the effect of facilitated tucking position during endotracheal suctioning on physiological criteria and behavioural responses of the preterm neonates.
- Trial name
- NCT06428916
- Testing
- tucking position during endotracheal suctioning
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Acute Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
Invasive Ventilation Strategies for Neonates With Acute Respiratory Distress Syndrome Syndrome (ARDS)
Acute respiratory distress syndrome (ARDS) in neonates has been defined in 2017.The death rate is over 50%. HFOV and CMV are two main invasive ventilation strategies. However, which one is better needing to be further elucidated.
- Conditions
- Acute Respiratory Distress Syndrome, Bronchopulmonary Dysplasia, High Frequency Oscillation Ventilation
- Trial name
- NCT03372525
- Testing
- HFOV, CMV
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Fetal Distress, Fetal Hypoxia
Application of Electronic Endoscope in Fetal Distress
Fetal distress is a common emergency in obstetrics, which refers to the combined symptoms of fetal health and life in utero due to acute or chronic hypoxia, with an incidence of 2.7% to 38.5%.
- Trial name
- NCT06608654
- Testing
- endoscope application
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Respiratory Distress Syndrome
Study of Energy Requirements in Critically Ill Newborns
OBJECTIVES: I. Determine the total energy expenditure in term and preterm infants in both well and ill states using the doubly labeled water method.
- Trial name
- NCT00006274
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Mechanical Ventilation Complication, Respiratory Distress Syndrome in Premature Infant
Effect of Implementing Evidence Based Practices on Prevention of Associated Nasal Pressure Injuries Among Preterm Neonates With Non-Invasive Respiratory Support
This study aims to evaluate the effect of implementing evidence based practices on prevention of associated nasal pressure injuries among preterm neonates with non invasive respiratory support
- Trial name
- NCT06642285
- Testing
- Non Invasive Respiratory Support bundle
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Respiratory Distress Syndrome In Premature Infants
Safety and Efficacy Study of the Draeger Babylog VN500 Device in HFOV Mode in VLBW Neonates
The purpose of this study is to determine the safety and effectiveness of the Babylog VN500 in high frequency oscillatory ventilation (HFOV) mode as a method for treating very low birth weight (VLBW) neonates requiring invasive…
- Trial name
- NCT02445040
- Testing
- Babylog VN500 in HFOV Mode
- Where
- 14 sites in United States
- Volunteers
- 225 people
- Sponsor
- Draeger Medical Systems, Inc.
Respiratory Distress of Newborn
Comparison of Continuous Positive Airway Pressure and Non Invasive Positive Pressure Ventilation
The objective of the study is to compare the effectiveness of treatment with Non Invasive Positive Pressure Ventilation (NIPPV) and continuous positive airway pressure (CPAP) in decreasing the requirement for endotracheal…
- Trial name
- NCT03347136
- Testing
- CPAP, NIPPV
- Where
- Sri Lanka
- Volunteers
- 80 people
- Sponsor
- Ministry of Health, Sri Lanka