Clinical trials: Respiratory Distress Syndrome (RDS)
Respiratory Distress Syndrome, Adult, Sepsis
Early Insulin and Development of ARDS
Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) is a severe lung condition that causes respiratory failure. Symptoms usually develop within 24 to 48 hours of an original injury or illness, and people with…
- Conditions
- Respiratory Distress Syndrome, Adult, Sepsis, Hyperglycemia
- Trial name
- NCT00605696
- Testing
- Insulin
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Albert Einstein College of Medicine
Prone Position, Acute Respiratory Distress Syndrome
Prone Position With Different Types of Cushions in Patients With ARDS
The prone maneuver is a well-established therapy in ARDS. Traditionally, the maneuver is perform with thoraco-abdominal cushions.
- Trial name
- PronEIT (NCT06184490)
- Testing
- Prone position with thoraco-abdominal cushion
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
COVID-19 Infection
Clazakizumab vs. Placebo - COVID-19 Infection
The purpose of this study is to investigate the effectiveness and safety of treatment with clazakizumab compared to a placebo (inactive substance).
- Trial name
- NCT04494724
- Testing
- Clazakizumab
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Methodist Hospital Research Institute
Mild to Moderate Acute Respiratory Distress Syndrome
Post-Market Study of Low-flow ECCO2R Using PrismaLung+
PrismaLung+ is intended to provide extracorporeal carbon dioxide removal (ECCO2R) as a standalone therapy or in combination with continuous renal replacement therapy (CRRT).
- Trial name
- NCT04617093
- Testing
- PrismaLung+
- Where
- 10 sites in France
- Volunteers
- 63 people
- Sponsor
- Vantive Health LLC
ARDS, Human
Optimal PEEP Titration Combining Transpulmonary Pressure Measurement and Electric Impedance Tomography
Diagnosis and treatment of the hypoxic respiratory failure induced by severe atelectasis with the background of acute lung injury is challenging for the intensive care physicians.
- Trial name
- NCT04174014
- Testing
- Recruitment manoeuvre
- Where
- Hungary
- Volunteers
- 10 people
- Sponsor
- Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged
Respiratory Distress Syndrome, Transient Tachypnea of Newborn
The Predictive Value of Amniotic Fluid pH and Electrolytes on Neonatal Respiratory Disorders
Amniotic fluid (AF) is a complex structure with a changing content by gestational time. AF pH can be affected by both maternal and fetal conditions such as preterm ruptures of membranes, prematurity and fetal distress.
- Trial name
- NCT02813954
- Testing
- Blood Gas Sampling
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Respiratory Distress Syndrome, Ventilation Therapy; Complications
Changes in Lung Aeration and Inspiratory Effort With and Without Awake Prone
The investigators aimed to investigate the ventilation homogeneity and transpulmonary pressure during treatments of High-flow nasal cannula(HFNC) and (CPAP) on supine and prone position for COVID-19 or non-COVID-19 patients with…
- Trial name
- NCT05719103
- Testing
- With and Without Awake Prone Positioning
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Shanghai Zhongshan Hospital
Critical Illness, Sepsis
Peer Support for Post Intensive Care Syndrome Self-Management
A prospective, 2-arm, single-blind, randomized controlled clinical feasibility trial design is planned. Forty CCI survivors will be randomized (1:1) to either the PS-PICS (peer support) intervention or usual care (control) group.
- Conditions
- Critical Illness, Sepsis, Shock, Septic, Shock
- Trial name
- PS-PICS (NCT03788096)
- Testing
- Peer Support with Motivational Interviewing, Usual Care Group
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas at Austin
Acute Respiratory Failure
Physiological Effects of a New Interface on Lung Ventilation and Gas Distribution
Hypoxemic Acute Respiratory Failure (hARF) is a common reason of admission to Intensive Care. Different modalities can be used to administer oxygen, which is the first supportive treatment in these patients.
- Trial name
- NCT04619641
- Testing
- High Flow Nasal Cannula (HFNC), Continuous Positive Airway Pressure (CPAP)
- Volunteers
- 15 people
- Sponsor
- University Magna Graecia
Lung Diseases, Respiratory Distress Syndrome
Clinical Interventions in Respiratory Distress Syndrome and Neonatal Lung Injury - SCOR in Lung Biology and Diseases in Infants and Children
To conduct clinical interventions directed at neonatal lung disease and injury, with a focus on infants having surfactant-deficiency or inactivation as a component of pathophysiology.
- Conditions
- Lung Diseases, Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
- Trial name
- NCT00005683
- Sponsor
- University of Rochester
Septic Shock, Adult Respiratory Distress Syndrome
Hyperoxia and Hypertonic Saline in Septic Shock
Assessment of the effect of hyperoxia and hypertonic saline on survival in patients with septic shock Hyperoxia and hypertonic saline may have beneficial effects on organ perfusion and oxygenation and may reduce the organ failure…
- Trial name
- Hyper2S (NCT01722422)
- Testing
- oxygen and saline
- Where
- France
- Volunteers
- 441 people
- Sponsor
- University Hospital, Angers
ARDS
Preventive Strategies in Acute Respiratory Distress Syndrome (ARDS)
The investigators hypothesis is that patients at risk of ARDS, detected by LIPS (Lung Injury Prediction Score), under mechanical ventilation could benefit from a protective ventilatory strategy (used in ARDS treatment) in order…
- Trial name
- EPALI (NCT02070666)
- Testing
- Protective mechanical ventilation, Control group, Dead space
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Corporacion Parc Tauli
Bronchopulmonary Disease
Preterm Lung Patient Registry
The goal of the Preterm Lung Patient Registry is to collect data on individuals with neonatal lung disease to better understand the illness and ultimately improve their care and survival.
- Trial name
- NCT00951366
- Testing
- Patient Registry
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Boston Children's Hospital
Respiratory Distress Syndrome, Adult, Ventilator-Induced Lung Injury
Asynchrony During Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome
Asynchrony during mechanical ventilation has been poorly described in patients suffering from acute respiratory distress syndrome.
- Trial name
- NCT02732041
- Where
- 5 sites in Argentina
- Volunteers
- 103 people
- Sponsor
- Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno
COVID-19 Acute Respiratory Distress Syndrome
PRactice of Ventilation and Adjunctive Therapies in COVID-19 Patients.
PRactice of Ventilation and Adjunctive Therapies in COVID-19 Patients. An observational study of ventilation practice and adjunctive therapies in critically ill, invasively ventilated COVID-19 patients during the first and second…
- Trial name
- PRoVAcT-COVID (NCT05954351)
- Where
- Netherlands
- Volunteers
- 2,465 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Acute Respiratory Distress Syndrome
The Value of Serum MicroRNA-21-5p and LncRNAgadd7 Expression Levels in Predicting the Severity and Prognosis of ARDS ( Acute Respiratory Distress Syndrome )
By measuring the expression levels of MicroRNA-21-5p (miR-21-5p) and LncRNAgadd7 in the peripheral blood of ARDS patients, the study aims to explore the correlation between these levels and the severity and prognosis of ARDS.
- Trial name
- NCT06825754
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Shao Yuekai
Cardiac Arrest, Respiratory Distress Syndrome
Pre Hospital Evaluation of Video Laryngoscopy
The objective of this work is to compare standard intubation with video laryngoscope (Glide scope Ranger ) in French pre hospital multicentric study.
- Conditions
- Cardiac Arrest, Respiratory Distress Syndrome, Shock, Acute Post-trauma Stress State
- Trial name
- EVE (NCT01374061)
- Testing
- Classical intubation, GLIDESCOPE
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Distress Syndrome, Adult
ART - Alveolar Recruitment for Acute Respiratory Distress Syndrome Trial
Acute respiratory distress syndrome (ARDS) is a common scenario in intensive care unit. Discussions about it is exponentially growing up due its high mortality rates all over the world and low quality of life among survivors.
- Trial name
- ART (NCT01374022)
- Testing
- ART Strategy, ARDSNet Strategy
- Where
- Brazil
- Volunteers
- 1,013 people
- Sponsor
- Hospital do Coracao
Respiratory Distress Syndrome
Verification of Pulse Oximetry in Neonatal Population
The purpose of this his post-market, observational study titled Verification of Pulse Oximetry in the Neonatal Population is to gather data to further support the accuracy of Nonin's pulse oximeters when used in the neonate…
- Trial name
- NCT00751439
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Respiratory Distress Syndrome
Prone Positioning vs. Prone Positioning and NO Inhalation in COVID-19 ARDS.
The investigators aim to investigate the effects of prone positioning and prone positioning with NO inhalation for COVID-19 patients with ARDS.
- Trial name
- NCT05715788
- Testing
- Nitric oxide, prone positioning
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Zhongshan Hospital