Clinical trials: Respiratory Distress Syndrome (RDS)
Injuries, Acute Brain
Protective Ventilatory Strategy in Severe Acute Brain Injury
Acute respiratory distress syndrome (ARDS) occurs in almost 20% of patients with severe acute brain injury and is associated with increased morbidity and mortality.
- Trial name
- PROLABI (NCT01690819)
- Testing
- Conventional Ventilatory Strategy, Protective Ventilatory Strategy
- Where
- Italy
- Volunteers
- 524 people
- Sponsor
- University of Turin, Italy
ARDS, Human, Mechanical Ventilation Complication
Smartphone Application for Initiation of Protective Ventilation. Clinical Impact of Instrumental Dead Space Reduction
Clinical evaluation of a new educative tools (Smartphone application) based on impact of instrumental dead space reduction after initiation of protective ventilation during mechanical ventilation.
- Conditions
- ARDS, Human, Mechanical Ventilation Complication, Humidifier Lung
- Trial name
- Ventilo (NCT04390360)
- Testing
- Protective ventilation implementation, Protective ventilation with HME, Protective ventilation with Heated humidifier
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Laval University
Acute Respiratory Distress Syndrome in Children
Assessment of Airway Opening Pressure in Invasively Ventilated Children
Acute respiratory distress syndrome (ARDS) in children is associated with significant morbidity and mortality. Current studies seek to individualize the management of children by defining several phenotypes, based until now…
- Trial name
- AOP-KID (NCT07262541)
- Testing
- Measurement of airway opening pressure
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Distress Syndrome, Adult, Covid19
High-Dose Vitamin C Treatment in Critically Ill COVID-19 Patients
Acute respiratory failure due to COVİD-19 pneumonia has poor prognosis and high mortality . Both the lack of an effective antiviral treatment and the low level evidence of the recommendations presented in the guidelines on other…
- Trial name
- NCT04710329
- Testing
- Ascorbic acid
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Respiratory Distress Syndrome (RDS), Neonatal Diseases and Abnormalities
Nasal High Frequency in Preterm Neonates
One of the most commonly used non-invasive methods is nasal continuous positive airway pressure (nCPAP). Although high frequency ventilation (HFV) has been applied in many neonatal intensive care units, nasal high frequency…
- Trial name
- NCT06687083
- Testing
- nasal high frequency oscillatory ventilation mode, nasal continuous positive pressure ventilation mode
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Coronavirus, SARS-CoV-2
Hemodynamic Characteristics of Patients With SARS-CoV-2
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been declared a public health emergency of international concern.
- Conditions
- Coronavirus, SARS-CoV-2, COVID-19, Acute Respiratory Distress Syndrome
- Trial name
- PiCCOVID (NCT04337983)
- Testing
- Transpulmonary thermodilution, Echocardiography
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Bicetre Hospital
ARDS (Acute Respiratory Distress Syndrome), VILI (Ventilator-induced Lung Injury)
Real-Time Algorithm-Driven Ventilation Feedback to Improve Lung-Protective Ventilation in Patients With ARDS (REALVENT-study)
The REALVENT trial is designed to evaluate whether a real-time, algorithm-driven ventilation feedback strategy can improve lung-protective ventilation (LPV) achievement rates in critically ill patients receiving invasive…
- Conditions
- ARDS (Acute Respiratory Distress Syndrome), VILI (Ventilator-induced Lung Injury), Respiratory Failure, Critical Illness
- Trial name
- REALVENT (NCT07307066)
- Testing
- REal-time Algorithm-driven Ventilation feedback to improve lung-protective ventilation in critically, Standard ICU care
- Where
- China
- Volunteers
- 208 people
- Sponsor
- Peking Union Medical College Hospital
Deglutition Disorders, Respiratory Distress Syndrome In Premature Infants
Effect of Nasal Continuous Positive Airway Pressure on The Pharyngeal Swallow in Neonates
Oral feeding of neonates while on nasal continuous positive airway pressure (NCPAP) is a common practice in many neonatal intensive care units (NICU) all over the country.
- Conditions
- Deglutition Disorders, Respiratory Distress Syndrome In Premature Infants, Respiratory Aspiration, Newborn, Premature
- Trial name
- NCT02661256
- Testing
- NCPAP, Varibar® Thin Liquid Barium Sulfate for Suspension
- Volunteers
- 7 people
- Sponsor
- NYU Langone Health
Covid19, Acute Respiratory Distress Syndrome
The MEseNchymal coviD-19 Trial: MSCs in Adults With Respiratory Failure Due to COVID-19 or Another Underlying Cause
This is a pilot, multi-centre, open-label randomised controlled study to assess the early efficacy of intravenous (IV) administration of CYP-001 in adults admitted to an intensive care unit (ICU) with respiratory failure
- Trial name
- MEND (NCT04537351)
- Testing
- CYP-001
- Where
- 5 sites in Australia
- Volunteers
- 14 people
- Sponsor
- Cynata Therapeutics Limited
Respiratory Distress Syndrome, Adult, Septic Shock
Immunglobulin M Enriched Intra Venous Immunoglobulin (IVIG) Therapy in Adult Respiratory Distress Syndrom (ARDS) Patients
57 patients with Adult Respiratory Distress Syndrome (ARDS) requiring Extracorporeal membrane oxygenation (ECMO) therapy were analyzed retrospectively.
- Trial name
- IVIG (NCT02961166)
- Testing
- IgM enriched Immunoglobulins
- Where
- Germany
- Volunteers
- 57 people
- Sponsor
- University Hospital Tuebingen
Lung Injury, ARDS
Point-of-care Lung Ultrasound (POCUS)-Integrated Study of Admitted Patients With COVID-19
This study seeks to define the ultrasound profile of patients with COVID-19, and document the progression of these ultrasound findings to develop prognostication and clinical decision instruments that can help guide management of…
- Conditions
- Lung Injury, ARDS, Acute Cardiac Event, Covid19
- Trial name
- PIOS-COVID (NCT05228717)
- Testing
- Point of Care Ultrasound
- Where
- 4 sites in United States
- Volunteers
- 240 people
- Sponsor
- Olive View-UCLA Education & Research Institute
Pregnant Women Receive Celesten
Betamethasone and Severity of Hyaline Membrane Disease
Primary purpose: to study the relationship between betamethasone placental transfer and the occurrence and severity of the Hyaline Membrane Disease.
- Trial name
- b-Mhyalines (NCT01854840)
- Where
- France
- Volunteers
- 127 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Newborn Respiratory Distress Syndrome
HHHFNC (Heated Humidified High-Flow Nasal Cannula) Versus NCPAP for Respiratory Distress Syndrome of Prematurity
Preterm infants ranging from 29+0 to 36+6 weeks+days are randomly assigned to one of the following treatments as non invasive respiratory support if they develop mild to moderate Respiratory Distress Syndrome within 72 hrs from…
- Trial name
- NCT02570217
- Testing
- HHHFNC, NCPAP
- Where
- Italy
- Volunteers
- 316 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
ARDS, COVID-19
Monitoring Anticoagulation in Patients on ECMO for Severe Lung Failure
A monocentric observational study evaluates the accuracy of anticoagulation monitoring in critically ill patients on ECLS (extracorporeal life support) using new markers of the effect of direct thrombin inhibitors and also the…
- Trial name
- NCT06038682
- Testing
- Argatroban Injection, Heparin
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Respiratory Ilness, Respiratory Distress Syndrome, Adult
Effect of Implementing Sleep Care Bundle on Nurses' Practice and Patients' Outcomes
Sleep is a fundamental physiological requirement for the human body to heal and overcome an illness or injury . Good sleep is essential for patient recovery and restoration of normal daily functions .
- Trial name
- NCT06775210
- Testing
- supportive sleep care, care bundle
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Mansoura University
Covid-19, ARDS, Human
Nebulized Heparin for the Treatment of COVID-19 Induced Lung Injury
Randomized, placebo controlled study to determine if nebulized heparin may reduce the severity of lung injury caused by the novel coronavirus, also known as COVID-19
- Conditions
- Covid-19, ARDS, Human, Acute Lung Injury
- Trial name
- NCT04397510
- Testing
- Heparin, 0.9% Sodium-chloride
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Frederick Health
Acute Respiratory Distress Syndrome (ARDS)
Clinical Trial of CG-BM1 Allogeneic Human Bone Marrow Mesenchymal Stem Cell Injection in the Treatment of Acute Respiratory Distress Syndrome
1. To evaluate the safety and tolerability of CG-BM1 for the treatment of patients with Acute Respiratory Distress Syndrome. 2. To observe the preliminary effectiveness of CG-BM1 in treating Acute Respiratory Distress Syndrome…
- Trial name
- CGBM1-ARDS-I01 (NCT07892950)
- Testing
- CG-BM1
- Where
- China
- Volunteers
- 15 people
- Sponsor
- GuangZhou Cellgenes Biotechnology Co., Ltd.
Sepsis, ARDS (Acute Respiratory Distress Syndrome)
Research on Risk Assessment and Early Warning Models for Adverse Clinical Outcomes in Critically Ill Patients
This is a medical research study that uses information from past patient hospital records. It focuses on three serious conditions that often affect critically ill patients: sepsis (a life-threatening body-wide infection), ARDS (a…
- Conditions
- Sepsis, ARDS (Acute Respiratory Distress Syndrome), AKI - Acute Kidney Injury
- Trial name
- NCT07317817
- Testing
- No intervention (Observational study)
- Where
- China
- Volunteers
- 55,940 people
- Sponsor
- Chongqing Medical University
COVID-19
Decitabine for Coronavirus (COVID-19) Pneumonia- Acute Respiratory Distress Syndrome (ARDS) Treatment: DART Trial
This is a a randomized double blind placebo controlled Phase 2 trial with a 12 patient lead-in to evaluate safety, prior to full enrollment to an additional 28 patients (for a total of 40 patients) to assess efficacy of…
- Trial name
- DART (NCT04482621)
- Testing
- Decitabine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Johns Hopkins University
Surfactant Deficiency Syndrome Neonatal, Respiratory Distress Syndrome, Newborn
Fast Assessment of Surfactant Deficiency in Preterm Infants to Speed up Treatment
Recently the investigators have developed a point of care test (LS-test) to measure surfactant as lecithin in gastric aspirates from preterm infants.
- Conditions
- Surfactant Deficiency Syndrome Neonatal, Respiratory Distress Syndrome, Newborn, Bronchopulmonary Dysplasia
- Trial name
- FAST2 (NCT05638568)
- Testing
- LS test
- Where
- 4 sites in Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.