Clinical trials: Respiratory Infection Virus
Chronic Obstructive Pulmonary Disease
Human Immunodeficiency Virus (HIV)and Chronic Obstructive Pulmonary Disease (COPD)
Highly active antiretroviral therapy (HAART) has considerably improved survival of HIV-infected patients. Opportunist diseases and cancers linked to immunodepression have largely regressed.
- Trial name
- HIV and COPD (NCT01639274)
- Testing
- COPD prevalence
- Where
- France
- Volunteers
- 639 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Covid-19
Oral Curcumin, Quercetin and Vitamin D3 Supplements for Mild to Moderate Symptoms of COVID-19
The present study is aimed to investigate the treatment benefits of a combination of dietary supplements quercetin, curcumin and vitamin D3 as add-on therapy to the routine care for early mild symptoms of COVID-19 infection in…
- Trial name
- NCT04603690
- Testing
- Complementary therapy, Standard of care
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Long COVID-19
Long COVID-19 Intervention (COVIDL/MIQoL)
The goal of this clinical trial is to assess the effectiveness of a multicomponent intervention in individuals with Long COVID. The main questions it aims to answer are: Does the intervention increase quality of life, mental…
- Trial name
- COVIDL/MIQoL (NCT06492590)
- Testing
- Multicomponent intervention
- Where
- Spain
- Volunteers
- 74 people
- Sponsor
- Consorci Sanitari de Terrassa
Non Small Cell Lung Cancer, Influenza Vaccine
Impact of Inactivated Trivalent Influenza Vaccine on NSCLC Patients Receiving PD-1 / PD-L1 Inhibitors
This project is to assess the immunogenicity, safety and overall survival impact of intramuscular injection of trivalent influenza vaccine in non-small cell lung cancer (NSCLC) patients with PD-1/PD-L1 inhibitor treatment.
- Trial name
- NCT04355806
- Testing
- PD-1/PD-L1 inhibitors, Inactivated trivalent influenza vaccine
- Where
- 2 sites in China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Influenza, H1N1 2009 Influenza
Rapid Evaluation of Pandemic H1N1 Influenza Vaccine in Adults Receiving Seasonal Influenza Vaccine
The purpose of this study is to assess the safety and effectiveness (immune response) to a licensed H1N12009 influenza vaccine in adults when given at the same time or prior to the seasonal influenza vaccine.
- Trial name
- NCT01000584
- Testing
- Arepanrix, Vaxigrip 2009/2010
- Where
- 4 sites in Canada
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- David Scheifele
Coronavirus Infection
Early Intervention in COVID-19: Favipiravir Verses Standard Care
Currently we do not know how best to treat patients infected with COVID-19. This study is looking at whether randomising participants to either favipiravir or to usual care, can help patients with suspected or proven COVID-19…
- Trial name
- PIONEER (NCT04373733)
- Testing
- Favipiravir, Standard of care management
- Where
- 6 sites in Brazil, Mexico and 1 more
- Volunteers
- 502 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
SARS-CoV-2, Influenza
A Safety, Reactogenicity, and Immunogenicity Study of mRNA-1073 (COVID-19/Influenza) Vaccine in Adults 18 to 75 Years Old
The primary goal of this study is to evaluate the safety, reactogenicity, and immunogenicity of mRNA-1073 compared to co-administered mRNA-1010 and mRNA-1273 vaccines and to the individual vaccines alone in healthy participants.
- Trial name
- NCT05375838
- Testing
- mRNA-1073, mRNA-1010, mRNA-1273
- Where
- 14 sites in United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Tonsillitis, Hypertrophy
Immune Response To Intranasal Influenza Vaccination
This research during the last decade has focused on the kinetics of the systemic and local immune response to parenteral influenza vaccine in humans.
- Trial name
- NCT01866540
- Testing
- FLUENZ
- Where
- Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Covid19
Outpatient Use of Ivermectin in COVID-19
Covid 19, a novel coronavirus, causes infection that, while mild to moderate in many people, can lead to severe disease in a significant portion.
- Trial name
- NCT04530474
- Testing
- Ivermectin Pill
- Where
- United States
- Sponsor
- Temple University
Hemophilia Arthropathy
COVID-19 Quarantine on Musculoskeletal Status in Hemophilia
Background. The recurrence of hemarthrosis in patients with congenital coagulopathies favors the development of a progressive, degenerative and intra-articular lesion (hemophilic arthropathy) that mainly affects the knees, ankles…
- Trial name
- HemoCov (NCT04491318)
- Testing
- Observational
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Influenza, Common Cold
Pomegranate Products for Prevention of Common Cold
Pomegranate has a long history of use in folk medicine. There is vast data on the health benefits of pomegranate fruit and juice.
- Conditions
- Influenza, Common Cold, Cough, Headache
- Trial name
- NCT00617318
- Testing
- Pomegranate
- Where
- United States
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- Texas Heart Institute
Dysphagia, Covid19
Dysphagia Management During COVID-19 Pandemic
The current study is aimed to determine the procedures applied in the dysphagia clinics during the COVID-19 pandemic period. A questionnaire consisting of 30 questions will be implemented.
- Trial name
- NCT04509752
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
COVID-19
Safety and Immunogenicity Study of an Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19
This study is a randomized, double-blinded, and placebo-controlled phase Ia/IIa clinical trial of the Inactivated SARS-CoV-2 Vaccine to evaluate the safety and immunogenicity of the vaccine in healthy people aged 18~59 Years.
- Trial name
- NCT04412538
- Testing
- Low dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule, Low dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 14-day schedule, Medium dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule
- Where
- China
- Volunteers
- 942 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
Gastrinoma, Glucagonoma
Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors
RATIONALE: Everolimus and vatalanib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Conditions
- Gastrinoma, Glucagonoma, Insulinoma, Metastatic Gastrointestinal Carcinoid Tumor
- Trial name
- NCT00655655
- Testing
- everolimus, vatalanib, pharmacological study
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Mayo Clinic
COVID-19 Pandemic, COVID-19 Vaccines
UNAIR Inactivated COVID-19 Vaccine as Homologue Booster (Immunobridging Study)
The goal of this open-label clinical trial is to evaluate the safety and immunogenicity of INAVAC (Vaksin Merah Putih - UNAIR SARS-CoV-2 (Vero Cell Inactivated)) Vaccine as Homologue Booster in Adult Subjects in Indonesia.
- Conditions
- COVID-19 Pandemic, COVID-19 Vaccines, COVID-19 Virus Disease
- Trial name
- NCT06259578
- Testing
- INAVAC (Vaksin Merah Putih - UA- SARS CoV-2 (Vero Cell Inactivated) 5 μg
- Where
- Indonesia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Dr. Soetomo General Hospital
Respiratory Syncytial Virus Infections
A Study of the Safety and Efficacy of A-60444 in Adults With Respiratory Syncytial Virus (RSV) Infection Following HSCT
Objectives Primary Objectives: Pilot Study: A preliminary assessment of the exposure and safety of oral A-60444 in post-stem cell transplant patients with RSV infection.
- Trial name
- NCT00232635
- Testing
- A-60444
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Arrow Therapeutics
Pneumocystis Carinii Pneumonia
Corticosteroids Therapy and Pneumocystis Jirovecii Pneumonia (PCP)
To explore the effects of corticosteroid therapy on pulmonary fibrosis and potentially pneumothorax in patients with mild PCP (pO2 >70mmHg) combined with the standard of care treatment of antibiotic therapy.
- Trial name
- NCT00636935
- Testing
- Antibiotics only, Antibiotics + Corticosteroids, Corticosteroids + antibiotics
- Where
- United States
- Sponsor
- George Washington University
COVID-19, Asymptomatic COVID-19
A Clinical Evaluation of Proof Diagnostics Test System Including the Proof Diagnostics Reader and COVID-19 Test
To determine the accuracy of Proof Diagnostics COVID-19 Test in the intended, symptomatic and suspected/at-risk asymptomatic population and point-of-care use as compared to a standard molecular comparator, Quidel Lyra SARS-CoV-2…
- Trial name
- NCT05331976
- Testing
- Proof Lab Test System
- Where
- 3 sites in United States
- Volunteers
- 276 people
- Sponsor
- Proof Diagnostics
Diphtheria, Tetanus
Assessment of the Immunogenicity and Safety of PENTAXIM™ in Philippines
The present clinical study will assess the immunogenicity and reactogenicity of the subsequent administration of Aventis Pasteur's DTacP-IPV//PRP~T combined vaccine (PENTAVAC™/PENTAXIM), as a three-dose primary vaccination in 6…
- Conditions
- Diphtheria, Tetanus, Polio, Pertussis
- Trial name
- NCT00254917
- Testing
- Diphteria, Tetanus, Polio, Acellular Pertussis, Hib vaccine
- Where
- Philippines
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- Sanofi
COVID-19
Study for Efficacy and Safety Assessment of the Drug RADAMIN®VIRO for COVID-19 Postexposure Prophylaxis
This is Double-Blind, Placebo-Controlled Multicentre Clinical Phase III Study conducted in 10 medical facilities. The objective of the study is to evaluate efficacy and safety of the drug Drug RADAMIN®VIRO, Lyophilisate for…
- Trial name
- NCT05722691
- Testing
- Double-Stranded RNA sodium salt
- Where
- 10 sites in Russia
- Volunteers
- 800 people
- Sponsor
- Promomed, LLC